Posted at the Institutional Resources for Unique Collection and Academic Archives at Tokyo Dental College, Available from http://ir.tdc.ac.jp/
Title
A novel calcium phosphate bone graft for socket
preservation
Author(s)
Wei, Jen, Chang
Journal
歯科学報, 113(4): 418-418
URL
http://hdl.handle.net/10130/3149
Tooth extraction is one of the most widely performed procedures in dentistry today and it has been histori-cally well documented that this procedure may induce significant dimensional changes of the alveolar ridge. Past studies have concluded that human reentry studies showed horizontal bone loss of 29% to 63% and vertical bone loss of 11% to 22% after 6 months following tooth extraction. In the past decades, a lot of the biomaterials were developed to preserve the bone volume after tooth extraction.
Type I collagen which is the main component of extracellular matrix of bone tissue that can serve as an ex-cellent delivery system for growth factor and assist the angiogenesis. Calcium phosphate ceramics have been investigated extensively because their mineral chemistry resembles that of human bone. Therefore, the collagen bone graft matrix used in this study is a mixture consisting of bioresorbable purified fibrillar collagen and hydroxyapatite/β-tricalcium phosphate（HAp/β-TCP）ceramic.
In this study, a novel HA/β-TCP-collagen composite, collagen, bovine xenograft collagen were investigated under anethesia. Quantative analysis of the extraction ridge and histological analysis were done. The results showed HA/β-TCP-collagen composite performed as a newly biomimetic composite biomaterial that com-bines osteoconductivity with osteoinductivity in the socket bone preservation after tooth extraction.
≪プロフィール≫
＜略 歴＞
１９９５年 DDS, Taipei Medical University, Taipei, Taiwan
１９９７年 MSD, Taipei Medical University, Taipei, Taiwan
２００５年 PhD, School of Dentistry at Matsudo, Nihon University, Japan
２００７年−２０１１年 Assistant Professor, College of Oral Medicine, Taipei, Taiwan
２００７年− Board Director, Academy of Dental Implantology, ROC, Taiwan
２０１１年− Associate Professor, College of Oral Medicine, Taipei, Taiwan
２０１１年− Associate Secretary General, Taiwan Dental Association, Taiwan
A novel calcium phosphate bone graft for socket preservation
Wei Jen Chang DDS, MS, PhD
Associate Professor School of Dentistry, College of Oral Medicine, Taipei Medical University
姉妹校交流招待講演
学 会 講 演 抄 録 ４１８
