研究業績・活動報告2009

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(1)東北大学多元物質科学研究所. 研究業績・活動報告 2009 年 (平成 21 年)12 月. Institute of the Multidisciplinary Research for Advanced Materials Tohoku University Sendai, Japan.

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(3) 多元物質科学研究所. 研究業績・活動報告目次研究活動報告 ·········································································· 多元設計研究部門 ·············································································································. 1 1. 多元制御研究部門 ············································································································· 27 多元解析研究部門 ············································································································· 40 融合システム研究部門 ······································································································· 63 資源変換・再生研究センター ······························································································ 75 先端計測開発センター ······································································································· 97 多元ナノ材料研究センター ································································································· 107 新産業創造物質基盤技術研究センター ·················································································· 117 窒化物ナノ・エレクトロニクス材料研究センター ··································································· 119 寄附研究部門・研究ステーション ························································································ 131. 研究会報告 ············································································· 142 学会発表講演目録 ···································································· 186 多元設計研究部門 ············································································································· 186 多元制御研究部門 ············································································································· 205 多元解析研究部門 ············································································································· 225 融合システム研究部門 ······································································································· 240 資源変換・再生研究センター ······························································································ 259 先端計測開発センター ······································································································· 268 多元ナノ材料研究センター ································································································· 274 窒化物ナノ・エレクトロニクス材料研究センター ··································································· 282 寄附研究部門・研究教授・技術室・その他 ············································································ 289. 研究業績目録 ·········································································· 293 多元設計研究部門 ············································································································· 293 多元制御研究部門 ············································································································· 301 多元解析研究部門 ············································································································· 311 融合システム研究部門 ······································································································· 319 資源変換・再生研究センター ······························································································ 328 先端計測開発センター ······································································································· 337 多元ナノ材料研究センター ································································································· 341 新産業創造物質基盤技術研究センター ·················································································· 344 窒化物ナノ・エレクトロニクス材料研究センター ··································································· 346 寄附研究部門・研究教授・技術室・その他 ············································································ 350. 業績目録著者索引 ···································································· 353.

(4) 1. 研究活動報告. ࠙◊✲άືሗ࿌ࠚ㻌 ᩍ ෸ ຓ. ᩍ. ⾲㠃ᶵ⬟タィ◊✲ศ㔝㸦2009.1㹼2009.12㸧㻌 ᤵ㸸 ୍Ⰽ ᐇ ᤵ㸸 ୕ᮧ⪔ྖ ᩍ㸸 ᡴ㉺㞞ோ. ཷク◊✲ဨ㸸㔠ཎṇ඾ ༤ኈ◊✲ဨ㸸 ὥ┦㍤㸪ᮤග⇶ ኱ Ꮫ 㝔 ⏕㸸 ⸨⏣೺㈨㸪㔠ᐉ୰㸪ᚿ⏣㞝ኴ㸪Ọᶫᾈ஧㸪㤿ሙ♸ḟ㸪 ຍ⸨㈼୍㸪ඵᮌὒග㸪ᒣ⏣᫂ᚨ㸪ࣈ࢔ࢫࢵࢡ͌࢔࢝ࣛ ࣡ࢵࢺ㸪㟷ᒣఏ㸪ᐑ⬥኱㸪㛗ཎ໷♸ 㻌 ᮏ◊✲ศ㔝࡛ࡣࠊ㉸㧗⣧ᗘ⣲ᮦస〇ࡢࡓࡵࡢ⢭〇ᡭἲ࠾ࡼࡧࣉࣟࢭࢫࡢ㛤Ⓨࠊ㧗⣧ᗘ⣲ᮦࡢ≉ᛶゎ ᫂࡜୙⣧≀ࡢ୚࠼ࡿᙳ㡪ࡢゎ᫂➼࡟ࡘ࠸࡚◊✲ࢆ⾜ࡗ࡚࠸ࡿ㸬㻜㻥ᖺࡢ◊✲ࡣ௨ୗࡢࡼ࠺࡟ᴫᣓࡉࢀࡿ㸬㻌㻝㻚䜲䜸䞁஺᥮ἲ䛻䜘䜛㔠ᒓ䛾㧗⣧ᗘ໬䛻㛵䛩䜛◊✲㻌㏆ᖺࡢ༙ᑟయ㟁Ꮚ⏘ᴗ࡟࠾࠸࡚ࠊ㧗⣧ᗘ㔠ᒓࡢᙺ๭ࡣࡲࡍࡲࡍ㧗ࡲࡗ࡚ࡁ࡚࠸ࡿࠋ㧗⣧ᗘ㔠ᒓࢆస 〇ࡍࡿᡭẁ࡜ࡋ࡚‵ᘧ࡟ࡼࡿ⢭〇ἲࡣ㔜せ࡛࠶ࡾࠊᮏ◊✲ศ㔝࡛ࡣ≉࡟࣒࢝ࣛἲࢆ⏝࠸ࡓ࢖࢜ࣥ஺᥮ ἲ࡟╔┠ࡋ⣔⤫ⓗ࡞◊✲ࢆ⾜ࡗ࡚࠸ࡿࠋ࢖࢜ࣥ஺᥮⢭〇ἲ࡟࠾ࡅࡿᇶ♏ࡣࠊ⁐ᾮ࠿ࡽࡢྛ࢖࢜ࣥ✀ࡢ ࢖࢜ࣥ஺᥮ᶞ⬡࡬ࡢ྾╔࣭⬺㞳཯ᛂཬࡧ࣒࢝ࣛἲࢆ⏝࠸ࡓྛ࢖࢜ࣥ✀ࡢࢡ࣐ࣟࢺࢢ࣒ࣛⓗศ㞳࡛࠶ࡿࠋ ᮏᖺࡢ◊✲ᡂᯝࢆ௨ୗ࡟グࡍࠋ (a) ሷ㓟㓟ᛶỈ⁐ᾮ୰࡟࠾ࡅࡿMoཬࡧWࡢ㝜࢖࢜ࣥ஺᥮ᶞ⬡࡬ࡢ྾╔ᣲື 㧗⼥Ⅼ㔠ᒓࡢ⣧ᗘࢆ♧ࡍሙྜࠊ㧗⼥Ⅼ㔠ᒓྠኈࡢ┦஫ศ㞳ࡀᅔ㞴࡛࠶ࡾࠊࡲࡓ㏻ᖖࡢ⏝㏵࡛ࡣ㧗⼥ Ⅼ㔠ᒓࡢ㧗ᗘ࡞㝖ཤࡣồࡵࡽࢀ࡚࠸࡞࠸ࡓࡵࠊẕ㔠ᒓ௨እࡢ㧗⼥Ⅼ㔠ᒓࡣ୙⣧≀࡜ࡋ࡚⪃៖ࡋ࡞࠸ࡢ ࡀ୍⯡ⓗ࡛࠶ࡿࠋࡋ࠿ࡋ࡞ࡀࡽࠊ㔠ᒓᮏ᮶ࡢᛶ㉁ࢆ▱ࡿࡓࡵ࡟ࡣศ㞳ࡀᅔ㞴࡛࠶ࡿඖ⣲ࡢ㝖ཤࡣ୙ྍ Ḟ࡛࠶ࡿࠋMoࡣᾮᬗࣃࢿࣝࡢ㓄⥺ᮦ࡟ࡶ౑⏝ࡉࢀࠊ௒ᚋࠊ᭱ඛ➃㟁Ꮚࢹࣂ࢖ࢫ࡬ࡢ᭦࡞ࡿᛂ⏝ࡀᮇᚅ ࡉࢀࡿᮦᩱ࡛࠶ࡿࠋ௨ୖࡢほⅬ࠿ࡽMoࡢ㧗⣧ᗘ໬ᢏ⾡ࡢ☜❧ࡣ㔜せ࡛࠶ࡿ࡜⪃࠼ࡽࢀࡿࠋࡑࡇ࡛ࠊᮏ ᖺࡣMo࡜Mo࡟ከࡃྵࡲࢀࡿWࡢሷ㓟㓟ᛶ⁐ᾮ୰࡟࠾ࡅࡿ㝜࢖࢜ࣥ஺᥮ᶞ⬡࡬ࡢ྾╔ᣲືࢆㄪᰝࡋࡓࠋ (b) Cuࡢ㧗⣧ᗘ໬࡟㛵ࡍࡿ◊✲ ḟୡ௦ULSIࡢᐇ⌧࡟ࡣࠊCu㓄⥺ᖜࡢᚤ⣽໬(<100 nm)࡟క࠺㓄⥺᢬ᢠቑ኱࡟ࡼࡿ㓄⥺㐜ᘏࡀ኱ࡁ࡞ㄢ㢟࡛࠶ࡿࠋࡇࢀ࡟ᑐࡋࠊCuࡵࡗࡁ㓄⥺ࡢ㉸㧗⣧ᗘ໬࡟ࡼࡾ⤖ᬗ⢏ᚄࡢᆒ୍࣭⢒኱໬ࢆ⾜࠺ࡇ࡜࡛ࠊ㓄 ⥺᢬ᢠపῶࡀᮇᚅࡉࢀࡿࠋࡑࡢ㧗⣧ᗘ໬࡟ࡣཎᩱࡢ㧗⣧ᗘ໬ࡀᚲせ࡛࠶ࡿࠋᮏ◊✲ศ㔝࡛ࡣࡇࢀࡲ࡛ ࡟ࡶ౯ᩘไᚚ㝜࢖࢜ࣥ஺᥮ἲ࡟ࡼࡿCuࡢ㧗⣧ᗘ໬ࢆᐇ⌧ࡋ࡚ࡁࡓࡀࠊᚑ᮶ἲ࡛ࡣᕤ⛬ࡀ」㞧࠿ࡘᅇ཰ ⋡ࡀప࠸ࡓࡵᕤᴗ໬࡟ࡣ㐺ࡉ࡞࠸ࠋࡑࡇ࡛ࠊศ㞳ᕤ⛬ࢆ෌᳨ウࡋࠊከẁ࣒࢝ࣛἲࢆ᪂ࡓ࡟⪃᱌ࡋࡓࠋ ᮏᖺࡣከẁ࣒࢝ࣛἲ࡟ࡼࡿCuࡢ⢭〇ຠ⋡ࠊᅇ཰⋡ࢆㄪᰝࡋࠊᮏἲࡀ㠀ᖖ࡟᭷⏝࡞᪉ἲ࡛࠶ࡿ஦ࢆ᫂ࡽ ࠿࡟ࡋࡓࠋ௒ᚋࡣࠊᐇ㝿࡟Cuࡢ⢭〇ࢆ⾜࠸ࠊ㔞⏘໬ᕤ⛬ࡢᐇ⌧ࡢᇶ♏ⓗ▱ぢࢆ⵳✚ࡍࡿࠋ (c) Hf࡜Zr࡜ࡢ┦஫ศ㞳࡟㛵ࡍࡿ◊✲ HfO2䜔ZrO2䛿La2O3➼䛸ඹ䛻ḟୡ௦ULSI䛾䝀䞊䝖⤯⦕⭷ᮦᩱ䛸䛧䛶ᮇᚅ䛥䜜䛶䛔䜛䚹ULSI䛻௦⾲䛥䜜䜛㟁 Ꮚ䝕䝞䜲䝇䛻౑⏝䛥䜜䜛ᮦᩱ䛿㧗⣧ᗘ䛷䛒䜛஦䛜せồ䛥䜜䜛䚹䛧䛛䛧䛺䛜䜙䚸HfO2䜔ZrO2䛾ཎᮦᩱ䛷䛒䜛Hf䜔 Zr䛾⣧ᗘ䛿⌧≧䛷඘ศ䛻㧗䛔䛸䛿ゝ䛘䛺䛔䚹≉䛻Hf䛸Zr䛾┦஫ศ㞳䛿㞴䛧䛟䚸ᕷ㈍㧗⣧ᗘရ䛻䛚䛔䛶䜒䚸Hf 䛻䛿Zr䛜0.1 mass%⛬ᗘ䚸Zr䛻䛿100 mass ppm⛬ᗘ䛾Hf䛾ΰධ䛜ぢ䜙䜜䜛䚹䛭䛣䛷䚸ᮏ◊✲ศ㔝䛷⣔⤫ⓗ䛻 ◊✲䛧䛶䛝䛯㝜䜲䜸䞁஺᥮⢭〇ἲ䛻䜘䜛Hf䛸Zr䛾ศ㞳䜢᳨ウ䛩䜛஦䛸䛧䛯䚹௒ᖺᗘ䛿䚸䛣䜜䜎䛷䛻᫂䜙䛛䛻䛧䛯 Hf䛸Zr䛾ሷ㓟⁐ᾮ୰䛻䛚䛡䜛㝜䜲䜸䞁஺᥮ᶞ⬡䜈䛾྾╔ᣲື䜢ᇶ䛻䚸ከẁ䜹䝷䝮ἲ䛻䜘䜛ศ㞳ᐇ㦂䜢⾜䛳䛯.

(5) 研究活動報告. 䛭䛾⤖ᯝ䚸Hf୰䛾Zr䜢1/300䛻ῶ䛪䜛஦䛾ฟ᮶䜛䝥䝻䝉䝇䜢㛤Ⓨ䛧䛯䚹䛣䛾᪉ἲ䛻䜘䜜䜀䚸୍⯡ⓗ䛻ᕷ㈍㧗⣧ ᗘHf䛻5,000 mass ppmྵ䜎䜜䜛Zr䜢15 mass ppm๓ᚋ䜎䛷㝖ཤྍ⬟䛷䛒䜚䚸ᚑ᮶ἲ䛷䛿ᚓ䜙䜜䛺䛛䛳䛯┿䛾㧗⣧ᗘHf䜢స〇ฟ᮶䜛஦䜢♧䛩䚹௒ᚋ䛿䜹䝷䝮䜢኱ᆺ໬䛧䚸ᐇ㝿䛻Zrྵ᭷㔞䛾ᑡ䛺䛔㧗⣧ᗘHf䜢స〇䛩䜛䚹䠎㻚㻌㧗⣧ᗘ㼆㼚㻻స〇䝥䝻䝉䝇䛾㛤Ⓨ䛸໬ᏛẼ┦㍺㏦ἲ䛻䜘䜛䠶䡊䠫䝞䝹䜽༢⤖ᬗ䛾ᡂ㛗㻌 ┤᥋㑄⛣ᆺ༙ᑟయZnO(Eg㸻3.4eV㸸ᐊ )ࡣⓎග⣲Ꮚ➼࡬ࡢᛂ⏝ࡀᮇᚅࡉࢀ࡚࠸ࡿࡀࠊఏᑟᆺ࠾ࡼࡧ Ḟ㝗ไᚚࡢᅔ㞴ᛶ➼ࡢၥ㢟ࢆ᭷ࡋࠊࡑࡢゎỴ࡟ࡣ㧗⣧ᗘZnO౑⏝ࡀ୙ྍḞ࡛࠶ࡿࠋᮏ◊✲࡛ࡣࠊᕷ㈍ࡢ 4NZnࢆཎᩱ࡟ࠊZnCl2HClỈ⁐ᾮ࡟ࡼࡿ㝜࢖࢜ࣥ஺᥮⢭〇ࢆ୺࡜ࡋࡓ㧗⣧ᗘZnO〇㐀ࣉࣟࢭࢫࢆ㛤Ⓨ ࡋࡓࠋࡉࡽ࡟ZnO༢⤖ᬗࢆ⫱ᡂࡋࠊ༙ᑟయ⏝⣲ᮦ࡜ࡋ࡚ࡢホ౯ࢆ⾜ࡗࡓࠋ㝜࢖࢜ࣥ஺᥮⢭〇࡛ࡣࠊ୺࡞ ୙⣧≀࡛࠶ࡿPb, Cu, Fe, Cd, Ag➼ࡀ㝖ཤࡉࢀࠊࡲࡓCl➼ࡢ୙⣧≀ࡣAr㞺ᅖẼ୰㧗 ↠↝(1473~1673K) ࡛ᴟపῶ໬ࡉࢀࠊ⣧ᗘ5N௨ୖࡢ㧗⣧ᗘZnOࢆᚓࡓࠋࡇࢀࢆཎᩱ࡟ࠊ໬Ꮫ㍺㏦ἲ࡟ࡼࡾ⫱ᡂࡋࡓZnO༢ ⤖ᬗࢆPL ᐃ࡛ホ౯ࡋࡓ⤖ᯝࠊ᫂░࡞ບ㉳ᏊⓎගࡀㄆࡵࡽࢀࠊ㧗ရ఩⤖ᬗ࡛࠶ࡿࡇ࡜ࢆ᳨ドࡋࡓࠋ 㻌䠏㻚㻌 Ỉ⣲䝥䝷䝈䝬⁐ゎ䛻䜘䜛㧗⼥Ⅼ㔠ᒓ䛾㧗⣧ᗘ໬㻌 7Lࠊ7Lྜ㔠ࡢ㧗ရ఩໬ࢆ┠ⓗ࡟ࠊᕷ㈍ࡢࢫ࣏ࣥࢪ7L බ⛠⣧ᗘ㸣

(6) ࠊ7L$O9ྜ㔠 $O9

(7) ࢆࠊa+$Uࣉࣛࢬ࣐⁐ゎ Ẽᅽࠊ㹼PLQ

(8) ࡋࠊ୙⣧≀ࡢ⵨Ⓨ㝖ཤࡸྜ㔠ᡂศࡢኚ໬࡟ᑐ ࡍࡿຠᯝࢆ᳨ウࡋࡓࠋࢫ࣏ࣥࢪ7L࡛ࡣࠊ7L࡟㍑࡭⵨Ẽᅽࡀ㧗࠸)H$O0Q&X&O➼ࡢ୙⣧≀ࡀࣉࣛࢬ࣐ Ỉ⣲⃰ᗘࡢቑຍ࡛ຠ⋡ⓗ࡟⵨Ⓨ㝖ཤࡉࢀࡓࠋ7L$O9ྜ㔠࡛ࡣࠊ$O⤌ᡂపୗࡣ㸣௨ෆ࡟ᢚ࠼ࡽࢀࠊ ș┦Ᏻᐃ໬ඖ⣲ࡢ)H6L1L&U➼ࡢ⵨Ⓨᦆኻࡶᑡ࡞ࡃࠊ୍᪉0Q1D0J3E&O࡞࡝⵨Ẽᅽࡀ┦ᙜ࡟㧗࠸୙ ⣧≀ࡣ㎿㏿࡟㝖࠿ࢀࠊ7Lྜ㔠ࡢ㧗ရ఩໬࡟ᑐࡍࡿỈ⣲ࣉࣛࢬ࣐⁐ゎࡢ᭷⏝ᛶࡀ♧၀ࡉࢀࡓࠋ 㻌䠐㻚㻌䜲䜸䞁䝡䞊䝮䝕䝫䝆䝅䝵䞁ἲ䛸䛭䛾ᚋ䛾㓟໬ฎ⌮䛻䜘䜛㓟໬䠤䡂ⷧ⭷䛾స〇䛚䜘䜃ホ౯䛻㛵䛩䜛◊✲㻌㧗ㄏ㟁⋡ࢆ᭷ࡋࠊ6Lᇶᯈୖ࡛⇕ⓗ࡟Ᏻᐃ࡞+I2ⷧ⭷ࡣࠊ௒ᚋࡢ8/6,ࢤ࣮ࢺ⤯⦕⭷࡜ࡋ࡚ᮇᚅࡉࢀ࡚࠸ ࡿࡀࠊⷧ⭷ࡢ㧗ရ఩໬ࡸ࣮ࣜࢡ㟁ὶపῶ➼ࡀㄢ㢟࡛࠶ࡿࠋᮏ◊✲࡛ࡣ,%'ἲ࡟ࡼࡾ+Iⷧ⭷ᙧᡂᚋࠊప 㓟໬࡟ࡼࡾ+I2ⷧ⭷ࢆᙧᡂࡋࠊࡑࡢ⤌⧊ࡸ㟁Ẽⓗ≉ᛶࡢྥୖࢆᅗࡗࡓࠋ,%'࡛ࡣᇶᯈࣂ࢖࢔ࢫ 9

(9) ༳ ຍ࡛⦓ᐦ࣭ᖹ⁥࡞+Iⷧ⭷ࡀᚓࡽࢀࠊࡇࢀࢆప 㓟໬㸦㓟⣲Ẽὶ୰ࠊΥࠊ㹼PLQ㸧ࡍࡿࡇ࡜࡛ࠊ ࣈࣜࢫࢱ࣮ࡢ↓࠸࢔ࣔࣝࣇ࢓ࢫ+I2ⷧ⭷ࡀᙧᡂࡉࢀࡓࠋࡲࡓࠊప 㓟໬᫬࡟89↷ᑕࡍࡿࡇ࡜࡛໬Ꮫ㔞ㄽ ⓗ⤌ᡂ࡟㏆࠸ Ḟ㝗ࡢᑡ࡞࠸

(10) +I2ⷧ⭷ࡀᚓࡽࢀࠊ࣮ࣜࢡ㟁ὶࡢపῶ࡟᭷⏝࡞ࡇ࡜ࢆ᫂ࡽ࠿࡟ࡋࡓࠋ 㸳㔠ᒓࡢప 㓟໬࡟㛵ࡍࡿ◊✲ ᴟࡵ࡚ⷧ࠸㓟໬⭷ཌࡢ ᐃ࡟᭷⏝࡞ศග࢚ࣜࣉࢯ࣓ࢺ࣮ࣜἲࢆ⏝࠸ࠊ1ẼᅽO2ࡲࡓࡣAr+O2࢞ࢫ୰࡛ ࡢin-situ ᐃ࡟ࡼࡾࠊ㔠ᒓࡢప 㓟໬㸦ᐊ 㹼360Υ㸧࡟㛵ࡍࡿ⣔⤫ⓗ࡞◊✲ࢆ㐍ࡵ࡚࠸ࡿࠋ๓ᖺᗘࡣࠊ Cu༢⤖ᬗࢆᑐ㇟࡟ࠊ㓟໬㏿ᗘࡣ(100)»(111)>(110)࡛㠃᪉఩౫Ꮡᛶࡀ࠶ࡿࡇ࡜ࠊࡲࡓ㓟໬ᶵᵓࡢ⭷ཌ౫Ꮡ ᛶ(⣙5 nm௨ୗ࡛㏫ᑐᩘ๎ࠊ5~25 nm࡛୕஌๎ࠊ⣙25 nm௨ୖ࡛ᨺ≀⥺๎)ࢆ᫂ࡽ࠿࡟ࡋࡓࠋᮏᖺᗘࡣNi ༢⤖ᬗ(100), (110), (111)ࡢప 㓟໬ࢆ᳨ウࡋࡓࠋCu࡜ྠࡌࡃNiࡢሙྜࡶ⭷ཌ౫Ꮡࡀほᐹࡉࢀࠊ⣙40 n m௨ୗ࡛㏫ᑐᩘ๎ࠊ40 nm௨ୖ࡛୕஌๎࡟ᚑ࠺ࡇ࡜ࢆ᫂ࡽ࠿࡟ࡋࡓࠋ 㻌䠒㻚㻌 ᨺᑕ⥺᳨ฟჾ⏝໬ྜ≀༙ᑟయ䛾㧗⣧ᗘ໬䛻㛵䛩䜛◊✲㻌㻌㻌 ᨺᑕ⥺᳨ฟჾ⏝ᮦᩱ࡟ࡣࠊ㧗᢬ᢠ࠿ࡘ࢟ࣕࣜ࢔ࡢ㧗⛣ືᗘࡀせồࡉࢀࡿࡓࡵࠊ㧗⣧ᗘ໬ࡀᚲせ࡜ࡉ ࢀࡿࠋ3E,ࡣ᳨ฟ≉ᛶࡢ㧗ឤᗘ໬ࡢせᅉ࡛࠶ࡿཎᏊ␒ྕࡀ኱ࡁࡃࠊᨺᑕ⥺᳨ฟჾ⏝ᮦᩱ࡜ࡋ࡚ὀ┠ࡉࢀ ࡚࠸ࡿࡀࠊᕷ㈍ᮦᩱࡢ⣧ᗘࡣప࠸ࡢࡀ⌧≧࡛࠶ࡿࠋᮏᖺᗘࡣࠊ+:(ἲ࡟ࡼࡿⷧ⭷ᙧᡂࢆヨࡳࡿ࡜࡜ࡶ࡟ࠊ ༢⤖ᬗᡂ㛗ἲࢆ☜❧ࡋࠊཎᩱ⣧ᗘ࡜ᨺᑕ⥺᳨ฟ≉ᛶ࡜ࡢ㛵ಀࢆ᫂ࡽ࠿࡟ࡋࡓࠋ㻌. 2.

(11) 3. 研究活動報告. 䛆◊✲άືሗ࿌䛇㻌㻌 ᩍ ຓ. ගᶵ⬟タィ◊✲ศ㔝䠄2009䠊1䡚2009䠊12䠅㻌 ᤵ㻌㻦࿴⏣೺ᙪ㻌 ᩍ㻌㻦Ⲩᮌಖᖾ㻘㻌 ᆏᮏΎᚿ㻌. ኱ Ꮫ 㝔 ⏕㻌㻦㐲⸨⤮᲍Ꮚ䠈ᑠ㔝ᑎెᏊ䠈ᑎෆ⨾㤶䠈ᮧୖ㻌 ៅ㻘㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌 Ⳣཎ㻌 ၏㻘㻌㧗ᶫಇ⾜㻘㻌 ⴗᗞᑦ㐨㻘㻌 Ỉ㇂㐩ဢ㻌㻌. ᮏ◊✲ศ㔝䛷䛿 DNA 䜔 RNA䚸䛭䛧䛶䝍䞁䝟䜽㉁䛺䛹⏕య㧗ศᏊ䛾ḟୡ௦䜲䞁䝔䝸䝆䜵䞁䝖ᆺ䝘䝜䝞䜲䜸ᶵ ⬟ᮦᩱ䜈䛾ᛂ⏝䜔ගᶵ⬟ᮦᩱ䜈䛾ᒎ㛤䚸䛥䜙䛻⏕యศᏊ䛾ᵓ㐀ኚ໬䛸ᶵ⬟ไᚚ䛾ゎ᫂䜢┠ᣦ䛧䛯㧗᫬㛫ศ ゎ⬟෇஧Ⰽ䝇䝨䜽䝖䝹 ᐃ⿦⨨䛾㛤Ⓨ䜢┠ᣦ䛧䚸◊✲άື䜢⾜䛳䛶䛔䜛䚹2009 ᖺ䛾◊✲άື䛸䛧䛶䛿䚸௨ୗ 䛾䜘䛖䛻ᴫᣓ䛥䜜䜛䚹㻌㓝⣲άᛶࢆά⏝ࡋࡓ㑇ఏᏊ἞⒪⸆ຠᯝࡢ㣕㌍ⓗྥୖࢆ┠ᣦࡋࡓ࣌ࣉࢳࢻࣜ࣎᰾㓟࣌ࣉࢳࢻ᰾㓟 '1$ ࣓࢟ࣛேᕤ᰾㓟ࡢྜᡂ࡜ 51$ ㄆ㆑ไᚚ࠾ࡼࡧ 51DVH+ άᛶ࡟㛵ࡍࡿ◊✲ ᙜ◊✲ᐊ࡛ࡣࠊ࢞ࣥ⣽⬊≉␗ⓗ࢔ࣥࢳࢭࣥࢫ㑇ఏᏊ἞⒪⸆㛤Ⓨࢆ┠ᣦࡋࠊእ㒊่⃭ᛂ⟅ᆺேᕤ᰾㓟࡜ ࡋ࡚࣌ࣉࢳࢻࣜ࣎᰾㓟 (PRNA)ࢆタィ࣭ྜᡂࡋࠊሷᇶ㓄ิ≉␗ⓗ࡟┦⿵ⓗ࡞ DNA ࡜㘒ᙧᡂࡍࡿࡔࡅ࡛ ࡞ࡃࠊࡑࡢ㘒ᙧᡂ㺃ゎ㞳ࢆ࣍࢘◁Ꮡᅾୗࠊሷᇶ㒊ࡢ㓄ྥኚ໬ࢆ㥑ືຊ࡜ࡋ࡚ pH 6.2 ࡜ 7.2 ࡢ㛫࡛ on-off ไᚚྍ⬟࡛࠶ࡿࡇ࡜ࢆሗ࿌ࡋ࡚࠸ࡿ 1ࠋࡋ࠿ࡋࠊࡇࡢ PRNA-RNA 㘒యࡣ RNase H ࡢᇶ㉁࡟࡞ࡾ㞴࠸࡜ ண᝿ࡉࢀࡿࠋࡇࡢࡼ࠺࡞⫼ᬒࢆ㋃ࡲ࠼ࠊᮏᖺᗘࡣ mRNA ࡜ࡢ㘒యࡀ RNase H ࡢᇶ㉁࡜࡞ࡾࠊゐ፹㔞࡛ 㧗࠸࢔ࣥࢳࢭࣥࢫᶵ⬟Ⓨ⌧ࡀᮇᚅ࡛ࡁࡿ DNA ࡜ࠊᏳᐃ࡞㘒యࢆᙧᡂࡍࡿ PNA ࠾ࡼࡧㄆ㆑ไᚚᶵ⬟ࢆ ᢸ࠺ PRNA ࢆ⼥ྜࡋࡓ PRNA-PNA-DNA (PRPD)࣓࢟ࣛ (Figure 1)ࡢྜᡂ࡜᰾㓟ㄆ㆑࡞ࡽࡧ࡟ RNase H άᛶ࡟ࡘ࠸࡚ሗ࿌ࡋࡓࠋඛࡎึᮇⓗ࡞◊✲࡜ࡋ࡚ PRNA-PNA 㒊ศࡀ U/T 㐃⥆㓄ิ࡛࠶ࡿ PRPD ࣓࢟ࣛ ศᏊࡀྜᡂࡋࡑࡢ DNA ࡸ RNA ࡜ࡢ┦஫స⏝ࠊ࡞ࡽࡧ࡟ RNA ࡜ࡢ㘒యࡢ RNaseH άᛶ࡟ࡘ࠸࡚ホ౯ ࡋࠊⰋዲ࡞⤖ᯝࢆᚓࡓࠋࡋ࠿ࡋࠊࡇࡢ PRPD ࣓࢟ࣛศᏊࡣ୕㔜㙐ࢆᙧᡂࡋ࡚࠸ࡿࠋ࢔ࣥࢳࢭࣥࢫ㑇ఏ Ꮚ἞⒪⸆࡜ࡋ࡚ᛂ⏝ࡍࡿࡓࡵ࡟ࡣࠊ஧㔜㙐ࢆᙧᡂࡍࡿࣉ࣭ࣜࣥࣆ࣑ࣜࢪࣥΰྜ㓄ิࢆ᭷ࡍࡿ PRPD ࢟ ࣓ࣛศᏊࡢྜᡂࡀᚲせ࡛࠶ࡿࠋࡑࡇ࡛ࠊ஧㔜㙐ࢆᙧᡂࡍࡿࣉ࣭ࣜࣥࣆ࣑ࣜࢪࣥΰྜ㓄ิࢆ᭷ࡍࡿ PRPD ࣓࢟ࣛศᏊࢆྜᡂࡋࠊࡑࡢ᰾㓟ㄆ㆑࡞ࡽࡧ࡟ RNase H άᛶ࡟ࡘ࠸᳨࡚ウࡋࡓࠋ ࠙⤖ᯝ࣭⪃ᐹࠚ PRPD ࣓࢟ࣛ ࡣࠊDNA ⮬ືྜᡂᶵ࡟ ࡼࡾ࢔࣑ࣀᮎ➃ࢆ᭷ࡍࡿ DNA ࢆྜᡂ ࡋࡓᚋ࡟ࠊ⥆ࡃ CPG ୖ࡛ࡢ Fmoc ࣌ࣉ ࢳࢻᅛ┦ྜᡂἲ࡟ࡼࡾ Fmoc- PRNAࠊ Fmoc- PNA ࢆ㡰ḟᑟධࡍࡿࡇ࡜࡟ࡼ ࡾྜᡂࡋࠊHPLC ࡟ࡼࡾ༢㞳⢭〇ࡍࡿ ࡇ࡜࡟ࡼࡾᚓࡓࠋࡲࡓ⏕ᡂ≀ࡣ MALDI-TOF Mass ࡟ࡼࡾྠᐃࡋࡓࠋ PRPD ࣓࢟ࣛࡢሷᇶ㓄ิࡣ PRNA 㒊ࡀ U (PRPD1)ࠊPRNA 㒊ࡀ C (PRPD2)ࠊ PRNA 㒊ࡀ U ࡜ C (PRPD3)ࡢ୕✀㢮ࢆ ྜᡂࡋࡓࠋ. Figure 1. Chemical Structure of PRPD Chimera..

(12) 4. 研究活動報告. ᚓࡽࢀࡓ PRPD ࣓࢟ࣛࢆ⏝࠸ࠊ┦⿵ⓗ DNA ࡞ࡽࡧ࡟ RNA ࡟ᑐࡍࡿ㘒యㄆ㆑ไᚚ࡟ࡘ࠸᳨࡚ウࡋࡓࠋ ࡲࡎࡑࢀࡒࢀࡢ PRPD ࣓࢟ࣛ࡜ DNA ࡞ࡽࡧ࡟ RNA ࡜ࡢ㘒యࡣࠊCD ࢫ࣌ࢡࢺࣝ࠿ࡽ 1:1 㘒యࢆᙧᡂࡋ ࡚࠸ࡿࡇ࡜ࡀ♧၀ࡉࢀࡓࠋḟ࡟ PRPD ࣓࢟ࣛ࡜ DNA ࡞ࡽࡧ࡟ RNA ࡜ࡢ㘒యࡢᏳᐃᛶࢆ⼥ゎ ᗘ (Tm) ࢆᣦᶆ࡜ࡋ᳨࡚ウࡋࡓ (⾲ 1)ࠋPRPD ࣓࢟ࣛ࡜ DNA ࡜ࡢ㘒యࡢࡑࢀࡒࢀࡢ Tm ࡣࠊDNA/DNA 㘒యࡢ Tm ࡼࡾࡶᑠࡉ࠸್࡜࡞ࡗࡓࡀࠊPRPD/RNA 㘒యࡢ Tm ࡣ PRPD/DNA 㘒యࡢ Tm ࡟ẚ࡭࡚ 15 ᗘ௨ୖࡶ኱ࡁࡃࠊ PRPD ࣓࢟ࣛࡣ RNA ≉␗ⓗ࡟㘒యࢆᙧᡂࡍࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋࡲࡓࠊ㏫ࡢ㓄ྥᛶࡢ㓄ิࢆ᭷ࡍ ࡿ DNA ࡜ࡢΰྜ⣔࡟࠾࠸࡚ࡣࠊTm ࡀ 13 ᗘ௨ୖపୗࡍࡿࡇ࡜࠿ࡽࠊPRPD ࣓࢟ࣛࡣ࢔ࣥࢳࣃࣛࣞࣝ㓄 ྥᛶࢆ᭷ࡋ࡚࠸ࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋࡲࡓࡇࡢᏳᐃ࡞ PRPD/RNA ࠾ࡼࡧ PRPD/DNA 㘒య࡟ 20 mM ࡢ࣍࢘◁ࢆῧຍࡍࡿ࡜ Tm ࡣ 5 ᗘ⛬ᗘపୗࡋࠊ࣍࢘㓟ࢆእ㒊ᅉᏊ࡜ࡍࡿᶆⓗ RNA ࡟ᑐࡍࡿㄆ㆑࣭㘒య ᙧᡂไᚚᶵ⬟ࢆ᭷ࡍࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋ ḟ࡟ࠊPRPD2ࠊPRPD3 ࠾ࡼࡧ PRPD4 ࡜ RNA ࡜ࡢ㘒యࡢ RNase H άᛶ࡟ࡘ࠸࡚ DNA/RNA 㘒యࡢษ ᩿άᛶ࡜ẚ㍑᳨ウࡋࡓࠋ㓝⣲ RNase H ࡣࠊE.Coli RNase H1 (Mw; 17569.96, 0.049 mg/ml (0.1 OD))ࢆ⏝࠸ ࡓࠋࡇࡢᐇ㦂ࡣࠊ1 mol ࡢ PRPD ࡸ DNA ࡜ࠊ5’ᮎ➃࡟ FAM ࡛⺯ගᶆ㆑ࡋࡓ 3 ➼㔞࡜㐣๫㔞ࡢ RNA ࡜ΰྜࡋࠊ㘒యࢆᙧᡂࡉࡏࠊࡓ (80 Υ࡛ 30 ⛊㛫ࢹࢼࢳ࣮ࣗࣞࢩࣙࣥࡋࠊ60 Υ (10 ศ㛫)ࠊ40 Υ (10 ศ㛫)ࠊ37 Υ (10 ศ㛫)࡜ᚎࠎ࡟ ᗘࢆୗࡆ࡚࠸ࡁࠊ㘒యࢆᙧᡂࡉࡏࡿ)ࠋࡇࡢࡼ࠺࡟ RNA ࢆ 3 ➼㔞ຍ ࠼ࡓ⌮⏤ࡣࠊRNA ษ᩿ᚋࠊPRPD ࡀษ᩿ࡉࢀࡓ RNA ࠿ࡽゎ㞳ࡋࠊPRPD ࡀ෌ࡧᮍษ᩿ࡢ RNA ࡜㘒య ࢆᙧᡂࡋࠊゐ፹ⓗ࡟ᶵ⬟ࡍࡿࡇ࡜ࢆ☜ㄆࡍࡿࡓࡵ࡛࠶ࡿࠋ⤖ᯝࡶేࡏ࡚ሗ࿌ࡍࡿࠋRNA ษ᩿ຠ⋡ࢆࢹ ࣥࢩࢺ࣓࣮ࢱ࣮ࢆ⏝࠸࡚⟬ฟࡋࠊᐃ㔞ⓗ᳨ウࢆ⾜ࡗࡓ⤖ᯝࠊRNase H ⃰ᗘࡀ 5.6ࠊ2.8 nM ࡢ᮲௳࡛ࡢษ ᩿ຠ⋡ࡣࠊPRPD3 > PRPD2 > PRPD4 Ҹ DNA ࡜࡞ࡾࠊPRPD3 ࡜ PRPD2 ࡣ DNA/RNA 㘒యࡼࡾ㧗ຠ⋡࡟ ษ᩿ࡉࢀࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡾ㑇ఏᏊ἞⒪⸆࡜ࡋ࡚㠀ᖖ࡟ඃࢀࡓ≉ᛶࢆ᭷ࡍࡿࡇ࡜ࡀ♧ࡉࢀࡓࠋࡲࡓࠊ 㘒యᏳᐃᛶࡀ㧗࠸ PRPD2࣭RNA 㘒యࡼࡾࠊ㘒యᏳᐃᛶࡀ㧗࠸ PRPD3࣭RNA 㘒యࡀࡼࡾ㧗ຠ⋡࡟ษ᩿ ࡉࢀࡿ࡜࠸࠺⯆࿡῝࠸⤖ᯝࡀᚓࡽࢀࡓࠋࡲࡓࠊ௒ᅇࡢษ᩿ᐇ㦂᮲௳࡛ RNA ࡣ PRPDࠊDNA ࡟ᑐࡋ 3 ➼ 㔞ῧຍࡋ࡚࠾ࡾࠊ33㸣ษ᩿࡛➼㔞཯ᛂ࡛࠶ࡾ᭱኱ 3 ᅇゐ፹ⓗ࡟ᶵ⬟ࡍࡿࡇ࡜ࡀ࡛ࡁࡿࡀࠊࡇࡢ᮲௳࡛ ࡣࠊPRPD2 ࡣࠊPRPD3 ࡣ࠸ࡎࢀࡢ㓝⣲⃰ᗘ࡛ࡶษ᩿άᛶࡀ 33%ࡼࡾࡶ㧗ࡃࠊPRPD ࡣゐ፹ⓗ࡟ᶵ⬟ࡍࡿ ࡇ࡜ࡀ♧ࡉࢀࡓࠋ Table 1. Melting temperature of PRPD with DNA and RNA. 㻌. 㻌. 㻌. Tm/䉝 + borax Oligomer Sequence target DNA or RNA orientation 㻌 20 mM PRPD1 Gly-tct-Uct-tct-cTNHG-AGG-C 5'-d(GCC-TCA-GAG-AAG-AAG-A) antiparallel 38.5 5'-d(AGA-AGA-AGA-GACTCC-G) parallel < 5 5'-r(GCC-UCA-GAG-AAG-AAG-A) antiparallel 53.8 DNA1 5'-d(TCT-TCT-TCT-CTG-AGG-C) 5'-d(GCC-TCA-GAG-AAG-AAG-A) antiparallel 45.5 㻌㻌 5'-r(GCC-UCA-GAG-AAG-AAG-A) antiparallel 53.6 Lys-tct-Cct-ctc-cCNHG-CCC-A 5'-d(TGG-GCG-GGA-GAG-GAG-A) antiparallel 50.2 45.9 PRPD2 5'-d(AGA-GGA-GAG-GGC-GGG-T) parallel 36.9 < 10 5'-r(UGG-GCG-GGA-GAG-GAG-A) antiparallel 69.3 65.3 PRPD3 Lys-tct-Cct-cUc-cCNHG-CCC-A 5'-d(TGG-GCG-GGA-GAG-GAG-A) antiparallel 31.6 25.8 < < 10 5'-d(AGA-GGA-GAG-GGC-GGG-T) parallel 10 5'-r(UGG-GCG-GGA-GAG-GAG-A) antiparallel 51.6 48.9 DNA2 5'-d(TCT-CCT-CTC-GGC-GGG-A) 5'-d(TGG-GCG-GGA-GAG-GAG-A) antiparallel 58.6 㻌㻌 5'-r(UGG-GCG-GGA-GAG-GAG-A) antiparallel 70.1 69.6 㻌㻌㻌 [PRPD]=[DNA]= [RNA]=1.5 x 10-6 M in 33 mM phosphate buffer pH 7.2. 1) Wada, T.; Sato, H.; Inoue, Y. Biopolymers (peptide science). 2004, 76, 15..

(13) 5. 研究活動報告. . እ㒊่⃭ᛂ⟅ᆺࢱࣥࣃࢡ㉁ࡢᵓ⠏࡜⺯ග᳨ฟ࡬ࡢᛂ⏝࡟㛵ࡍࡿ◊✲. ග↷ᑕࡸ pH ኚ໬➼ࡢእ㒊่⃭ࡸ㓝⣲࡟ࡼࡿ௵ពࡢ⩻ヂᚋಟ㣭࡟ᛂࡌ࡚ࠊࡑࡢᶵ⬟ࡀάᛶ໬ྍ⬟࡞ ࢱࣥࣃࢡ㉁ࡢேᕤⓗᵓ⠏ࡣࠊࢱࣥࣃࢡ㉁ᕤᏛࡸࢼࣀࣂ࢖࢜ࢸࢡࣀࣟࢪ࣮ศ㔝࡟࠾ࡅࡿ㔜せ࡞◊✲ㄢ㢟 ࡢ୍ࡘ࡛࠶ࡿࠋࡲࡓࠊࡑࡢࡼ࠺࡞እ㒊่⃭ᛂ⟅ᆺࢱࣥࣃࢡ㉁ࡣࠊ⣽⬊ᶵ⬟ࡸ⏕యᶵ⬟㛵㐃ᮦᩱࡢ≉ᛶ ࢆ᫬✵㛫≉␗ⓗ࡟ไᚚྍ⬟࡞ேᕤศᏊࢫ࢖ࢵࢳ࡜ࡋ࡚ᛂ⏝ࡀᮇᚅࡉࢀࡿࠋᮏ◊✲࡛ࡣࠊศ๭ᆺࢱࣥࣃ ࢡ㉁࡜ேᕤࡢ่⃭ᛂ⟅㒊఩ࢆ⤌ࡳྜࢃࡏࡿࡇ࡜࡛ࠊ௵ពࡢእ㒊่⃭࡟ࡼࡗ࡚άᛶ໬ྍ⬟࡞ᶵ⬟ᛶࢱࣥ ࣃࢡ㉁ࡢ㛤Ⓨࢆ┠ᣦࡋ࡚࠸ࡿࠋࡇࢀࡲ࡛࡟ࠊศ๭ᆺ⥳Ⰽ⺯ගࢱࣥࣃࢡ㉁ (Split GFP) ୰࡟㠀ኳ↛ᆺග཯ ᛂᛶ㒊఩ࡸ㓝⣲཯ᛂᛂ⟅㒊఩ࢆྜ⌮ⓗ࡟」ྜ໬ࡍࡿࡇ࡜࡟ࡼࡗ࡚≉ᐃἼ㛗ࡢග↷ᑕ᫬ࡸࠊ㓝⣲Ꮡᅾୗ ࡟࠾࠸࡚⺯ගᙉᗘࡢቑຍࢆ♧ࡍ GFP ኚ␗యࡢタィࢆヨࡳ࡚ࡁࡓࠋ௒ᖺᗘࡣࠊศ๭ᆺ GFP ࢆ⏝࠸ࡓ࢝ ࢫࣃ࣮ࢮάᛶ᳨ฟࢩࢫࢸ࣒࡟㛵ࡋ࡚ࠊ㧗ឤᗘ໬࡜᳨ฟ㏿ᗘࡢྥୖ࡟ྲྀࡾ⤌ࢇࡔ (Figure 2)ࠋࡇࡢ⣔࡛ࡣࠊ ≉ᐃࡢ࢝ࢫࣃ࣮ࢮᏑᅾୗ࡟࠾࠸࡚ࡢࡳ⺯ගࢆ♧ࡍ GFP ኚ␗యࢆᵓ⠏ࡍࡿࡓࡵ࡟ࠊ C ᮎࣇࣛࢢ࣓ࣥࢺ ࡢ N ᮎ➃ഃ࡟࢝ࢫࣃ࣮ࢮࡢᇶ㉁㓄ิࢆ௜ຍࡋࠊ࣌ࣉࢳࢻࡢ N- ࠾ࡼࡧ C- ᮎ➃ࢆᯫᶫࡍࡿࡇ࡜࡛⎔ ໬ࡋ࡚࠸ࡿࠋ࢝ࢫࣃ࣮ࢮࢆᏑᅾୗࠊ࣌ࣉࢳࢻ୰ࡢᇶ㉁㓄ิ㒊఩ࡀ≉␗ⓗ࡟ษ᩿ࡉࢀࠊGFP N ᮎ᩿∦࡜ ࡢ෌⤖ྜࡀྍ⬟࡜࡞ࡿ⤖ᯝ࡜ࡋ࡚ࠊGFP ⺯ගᙉᗘࡢቑຍࡀᮇᚅ࡛ࡁࡿࠋ௒ᅇࠊC ᮎ᩿∦୰ࡢᩘ࢝ᡤ࡟ ఩⨨≉␗ⓗ࡞ኚ␗ࢆ᪋ࡍࡇ࡜࡛ࠊ෌ᵓᡂ㏿ᗘ࡜⺯ගᙉᗘࢆྥୖࡉࡏࡿࡇ࡜ࡀฟ᮶ࡓࠋࡲࡓࠊ࠶ࡽ࠿ࡌ ࡵࢡࣟࣔࣇ࢛࢔ࢆᙧᡂࡉࡏࡓ GFP N ᮎ᩿∦ࢆ⏝࠸ࡿࡇ࡜࡛ࠊ࢝ࢫࣃ࣮ࢮάᛶ࡟ᛂ⟅ࡋࡓ GFP ⺯ගᅇ ᚟㏿ᗘࢆ㣕㌍ⓗ࡟ྥୖࡉࡏࡿࡇ࡜ࡀྍ⬟࡜࡞ࡗࡓࠋ⌧ᅾࠊᮏࢫࢺࣛࢸࢪ࣮ࢆ␗࡞ࡿ⺯ග≉ᛶࢆ᭷ࡍࡿ ศ๭ᆺ CFP ࡸศ๭ᆺ YFP ࡟ᛂ⏝ࡍࡿࡇ࡜࡛ࠊ࣐ࣝࢳ࣮࣮࢝ࣛࣔࢻ࡟ࡼࡿ࢝ࢫࣃ࣮ࢮάᛶ᳨ฟࢩࢫࢸ ࣒ࡢᵓ⠏࡟ྲྀࡾ⤌ࢇ࡛࠸ࡿࠋ௒ᚋࡣࠊ⣽⬊ෆ⎔≧࣌ࣉࢳࢻྜᡂ⣔ࢆᵓ⠏ࡍࡿࡇ࡜࡟ࡼࡗ࡚ࠊ᫬✵㛫≉ ␗ⓗ࡞⏕యෆࣉࣟࢸ࢔࣮ࢮάᛶ᳨ฟ⣔࡟Ⓨᒎࡉࡏࡿணᐃ࡛࠶ࡿࠋ. Figure2. ศ๭ᆺ GFP ࢆ฼⏝ࡋࡓ࢝ࢫࣃ࣮ࢮάᛶ᳨ฟࢩࢫࢸ࣒ࡢᵓ⠏ 3. DNA-ligand 㛫⤖ྜࡢືⓗഃ㠃ࢆᤊ࠼ࡿ஦ࢆᚿྥࡋࡓ᫬㛫ศゎ෇஧Ⰽ ᐃἲࡢ㛤Ⓨ࡜ᛂ⏝ DNA-ligand 㛫䛾ືⓗഃ㠃䛻↔Ⅼ䜢䛒䛶䛯◊✲䛿䚸DNA䠉⸆๣. 䢷. 㛫┦஫స⏝䛾᭦䛺䜛⌮ゎ䛻⧅䛜䜚䚸䛥䜙䛻䛿⸆๣䛾᪂つ㛤Ⓨ䜈䛾▱ぢ䜈䛸⧅䛜䜛䜒䛾䛸ᮇᚅ䛥䜜䛶䛔䜛䚹DNA-ligand 㛫┦஫స⏝ DNA-ligand 㛫┦஫స⏝䜢⌮ゎ䛩䜛䝒䞊䝹䛸䛧䛶᭷⏝䛷䛒䜚䚸. 䢲. 䣅䣆䢢䢱䢢䣯䣦䣧䣩. 䛻䜘䜚ㄏ㉳䛥䜜䜛෇஧Ⰽᛶ(CD)䛿䚸⁐ᾮ୰䛷⡆౽䛛䛴ヲ⣽䛻. 䣕䣶䣧䣣䣦䣻䢢䣵䣶䣣䣶䣧䣌䣣䣵䣥䣱䢢䣌䢯䢺䢴䢲䢵䣯䣵. 䢯䢷. ᡃ䚻䛿䛭䛾ືⓗഃ㠃䜢᳨ウ䛩䜛䛯䜑䛾㧗᫬㛫ศゎ⬟䜢᭷䛩䜛 CD ᐃ⿦⨨䜢㛤Ⓨ䛧䛶䛔䜛䚹. 䢳䢲䢢䣵䢳䢢䣵. 䢯䢳䢲. ᮏᖺᗘ䛿䚸ᴃ෇೫ග䜢⏝䛔䛯 CD ᐃ⿦⨨䛻䛚䛔䛶䚸೫ගᏊ 䛾ᅇ㌿ゅ䛻౫Ꮡ䛧䛯ぢ䛛䛡䛾 CD ᙉᗘኚ໬䜢⌮ㄽⓗ䛻ண 䛧䚸䛛䛴ᐇ㦂ⓗ䛻ᐇド䛧䛯䚹೫ගᏊ䛾ゅᗘ䜢䝁䞁䝖䝻䞊䝹䛩䜛䛣䛸䛿 ᐇ㦂ⓗ䛻ᐜ᫆䛷䛒䜚䚸௒ᅇ䛾ᐇド䛛䜙䚸ᴃ෇೫ග䜢⏝䛔䛯 CD ᐃ ἲ 䛾 ⡆౽ 䛺㧗 ឤ ᗘ໬ 䜈䛾 ᣦ 㔪䛜 ᚓ 䜙䜜䛯䚹 ḟ 䛻 calf. 䢵䢷䢲. 䢶䢲䢲. 䢶䢷䢲䣙䣣䣸䣧䣮䣧䣰䣩䣶䣪䢢䢱䢢䣰䣯. 䢷䢲䢲. 䢷䢷䢲. Figure3. Laser-induced CD change observed in H2TMPyP (13 M) intercalated to ctDNA (500 M) in phosphate buffer (pH=6.9)..

(14) 研究活動報告. thymus DNA (ctDNA)䛸ග⥺ຊᏛ⒪ἲ䛷ᐇ⏝䛥䜜䛶䛔䜛Ỉ⁐ᛶ䝫䝹䝣䜱䝸䞁(H2TMPyP) 㛫┦஫స⏝䛷ほ䛥䜜䜛 CD 䝇䝨䜽䝖䝹䛾ගບ㉳䛻䛸䜒䛺䛖᫬㛫ኚ໬䜢 ᐃ䛧䛯䚹ගບ㉳┤ᚋ䛛䜙䝭䝸⛊䛻䛛䛡䛶䚸CD 䝇䝨䜽䝖䝹䛾 ኚ໬䛜ほ䛥䜜䛯(Figure 3)䚹H2TMPyP 䛿 ctDNA 䜈 intercalate 䛩䜛䛣䛸䛻䜘䜚㈇䛾 CD 䜢䚸side-bind 䛩䜛䛣䛸䛻䜘䜚ບ㉳Ꮚ┦஫స⏝ᆺ䛾 CD 䜢♧䛩䛣䛸䛜▱䜙䜜䛶䛔䜛䚹䛣䛾⤖ᯝ䛛䜙䚸ගບ㉳䛻䜘䜚 H2TMPyP 䛸 ctDNA 㛫䛾⤖ྜᵝᘧ䛜䜲䞁䝍䞊䜹䝺䞊䝖䛛䜙䚸ືⓗ䛻䝃䜲䝗䝞䜲䞁䝗ᆺ䜈䛸⛣⾜䛩䜛䛣䛸䜢♧䛧䛶䛔䜛䚹௒ᚋ䛿䚸ᚓ䜙䜜䛯 ⤖ᯝ䛾ᐃ㔞ⓗ䛺ゎᯒ䜢⾜䛖䚹 1.㻌 J. W. Lewis, R. F. Tilton, C. M. Einterz, S. J. Milder, I. D. Kuntz, D. S. Kliger J. Phys. Chem. 1985, 89, 289-294.. 6.

(15) 7. 研究活動報告. ࠙◊✲άືሗ࿌ࠚ 㔠ᒓᶵ⬟タィ◊✲ศ㔝㸦2009.1㹼2009.12㸧 ᩍ ᤵ㸸⶧ Ᏻ㑥 ෸ ᩍ ᤵ㸸டᒸ ⪽ ຓ ᩍ㸸⸨⏣ఙᑦ ᢏ ᐁ㸸኱ᶫ ㅍ ኱Ꮫ 㝔⏕㸸D2㸸㐲⸨ᡂ㍤ࠊM2㸸⳥ᆅ┿୍ࠊ᯽ᮌ♸௓ࠊ▼ཎ⏣ᖾኴࠊ ᒾ⏣ᩗྐࠊM1㸸▼ཎ኱㍤ࠊ㕥ᮌ೺ḟ㑻ࠊ㕥ᮌ஽⣖ GCOE ࣇ࢙࣮ࣟ㸸Can Cui ᮏ◊✲ศ㔝࡛ࡣࠊCan Cui Ặࡣᮏᅜ୰ᅜࡢ኱Ꮫࡢᩍ⫋࡟௜ࡃࡓࡵ࡟ࠊGCOE ࡢࣇ࢙࣮ࣟ࡜ࡋ࡚ࠊ㸷᭶ ࢆࡶࡗ࡚㏥⫋ࡋࡓࠋ㸲᭶ࡼࡾ◊✲ᐊ㓄ᒓࢆᕼᮃࡋࡓ኱Ꮫ㝔๓ᮇ㸰ᖺㄢ⛬▼ཎ኱㍤ࠊ㕥ᮌ೺ḟ㑻ࠊ㕥ᮌ ஽⣖ࡢ㸱ேࢆ⶧◊✲ᐊ࡜ࡋ࡚ཷࡅධࢀࠊ◊✲άືࡍࡿࡇ࡜࡜ࡋࡓࠋᮏ◊✲ศ㔝࡟࠾ࡅࡿ 2009 ᖺࡢάື ࢆᴫᣓࡍࡿ࡜௨ୗࡢ㏻ࡾ࡛࠶ࡿࠋ ‽⤖ᬗࡢ㸱ᅇᑐ⛠㠃ࡢ 670 ほᐹ ᫖ᖺᗘ࡛స〇ࡉࢀࡓ༢‽⤖ᬗ࠾ࡼࡧ㏆ఝ⤖ᬗࢆ⏝࠸࡚ࠊ670 ࡢ⾲㠃ほᐹࢆ⾜ࡗࡓࠋ‽⤖ᬗ࡟㛵ࡋ࡚ ࡣ㸱ᅇᑐ⛠㠃ࡢほᐹࢆ⾜࠸ከࡃࡢ⯆࿡῝࠸⤖ᯝࢆᚓ࡚࠸ࡿࠋᅗ㸯࡟♧ࡍࡼ࠺࡟ࡽࡏࢇ≧ࡢീࡀከࡃࡢ ሙᡤ࡛ほ ࡉࢀ࡚࠸ࡿࠋࡽࡏࢇࡢ୰ᚰ࡟ἢࡗ࡚ࠊࡽࡏࢇ㌿఩ࡀᏑᅾࡓࡿࡓࡵ࡟ࠊୖୗࡢ㠃ࡢ㛫࡟㸯ཎ Ꮚ㠃ࡢࡎࢀࡀ⏕ࡌࡓ࡜ᛮࢃࢀࡿࠋ௒ࡲ࡛‽⤖ᬗࡢ⾲㠃◊✲ࡣ୺࡟㸳ᅇᑐ⛠㠃࡟ࡘ࠸࡚⾜ࡗ࡚ࡁࡓࡀࠊ ࡇࡢࡼ࠺࡞ࡽࡏࢇ㌿఩࡜ᛮࢃࢀࡿࡼ࠺࡞Ḟ㝗ࡀࡵࡗࡓ࡟ほ ࡉࢀ࡚࠸࡞࠸ࠋṇ㸰㸮㠃య‽⤖ᬗ࡛ࡣከ ࡃࡢሙྜࡣṇ㸯㸰㠃యࡢᙧែࢆ♧ࡍࡇ࡜࠿ࡽࠊ࢚ࢿࣝࢠѸⓗ࡟㸳ᅇᑐ⛠㠃࡟ẚ࡭࡚㸱ᅇ㠃ࡢᏳᐃᛶࡀప ࠸࡜᥎ ࡛ࡁࡿࠋࡋࡓࡀࡗ࡚ࠊୖグࡢࡼ࠺࡞㌿఩ࡀほ ࡉࢀࡿࡇ࡜ࡣࠊ㸱ᅇᑐ⛠㠃ࡢ୙Ᏻᐃࡉ࡟⏤᮶ ࡍࡿ࡜⪃࠼ࡽࢀࡿࠋࡲࡓࠊ㧗ศゎ⬟ീ࡛ࡣࠊࢡࣛࢫࢱ࣮ࡽࡋࡁ༢఩ࡀ㸱ᅇᑐ⛠ࡢ㓄⨨ࢆ࡞ࡍࡇ࡜ࡀぢ ཷࡅࡽࢀࡿࡀࠊᵓ㐀ࣔࢹࣝ࡜ࡢᑐᛂࡣ᳨ウ୰࡛࠶ࡿࠋ. . ᅗ㸯 ,Q$J<E ‽⤖ᬗࡢ㸱ᅇᑐ⛠㠃ࡢ 670 ീ. ‽⤖ᬗศᩓ 0J ᢲฟᮦࡢస〇 ࣐ࢢࢿࢩ࣒࢘ 0J

(16) ྜ㔠࡟‽࿘ᮇᵓ㐀ࢆࡶࡘ‽⤖ᬗࢆศᩓࡉࡏࡿࡇ࡜࡛ᶵᲔ≉ᛶࡢྥୖࡀᚓࡽࢀࡿ.

(17) 8. 研究活動報告. 0J ྜ㔠ࡢᶵᲔ≉ᛶྥୖࡢࡓࡵ࡟࢖ࢵࢺ࣒ࣜ࢘➼ࡢᕼᅵ㢮ඖ⣲ 5(

(18) ࡀⰋࡃ⏝࠸ࡽࢀ࡚࠸ࡿࡀࠊࢥࢫ ࢺ㠃ࡸᕼᑡᛶࡢほⅬ࠿ࡽ 5( ౑⏝㔞ࡢ๐ῶࡸ௦᭰ࡀồࡵࡽࢀ࡚࠸ࡿࠋᮏ◊✲࡛ࡣࠊ⢊ᮎ෬㔠ἲࢆ⏝ ࠸࡚ 5( ࣇ࣮࡛ࣜ࠶ࡿ =Q0J=U ‽⤖ᬗࢆศᩓࡉࡏࡓ 0J ᢲฟᮦࡢస〇ࢆ⾜࠸ࠊ⤌⧊ほᐹ࠾ࡼࡧᶵᲔ ≉ᛶ࡟ࡘ࠸࡚ホ౯ࡋࡓࠋ㟁Ꮚࣉ࣮ࣟࣈ࣐࢖ࢡࣟ࢔ࢼࣛ࢖ࢨ㸦(30$㸧ࠊ; ⥺ᅇᢡ⿦⨨ ;5'

(19) ࠾ࡼࡧ㏱㐣ᆺ㟁Ꮚ㢧ᚤ㙾 7(0

(20) ࢆ⏝࠸࡚⤌⧊ほᐹ࡜┦ࡢ⤌ᡂศᯒࢆ⾜ࡗࡓ⤖ᯝࠊȣP ௨ୗࡢ‽⤖ᬗࡀ 0J ᇶᆅ࡟ᆒ୍ศᩓࡉࢀࡓ⤌⧊ࡀ☜ㄆࡉࢀࡓࠋࡲࡓࠊ;5' ࡟ࡼࡿᴟⅬᅗἲ࡜ (%6' ࡟ࡼࡿ㏫ᴟⅬᅗἲ࡟ ࡼࡿ࡜ࠊ⣧ 0J ᢲฟᮦ࡟ᙉࡃぢࡽࢀࡓ㞟ྜ⤌⧊ࡀ‽⤖ᬗศᩓᮦ࡛ࡣ⦆࿴ࡉࢀ࡚࠸ࡓࠋࡇࢀࡣࠊ0J ⢏᪉఩ࡢࣛࣥࢲ࣒໬ࡀ⏕ࡌࡓ࡜⪃࠼ࡽࢀࠊ0J ྜ㔠ࡢㄢ㢟࡛࠶ࡿኚᙧ␗᪉ᛶࡢ⦆࿴ࡸຍᕤᛶྥୖࡢ 㠃࡛ᮇᚅࡀࡶࡓࢀࡿࠋ‽⤖ᬗศᩓᮦ࡟࠾ࡅࡿᘬᙇヨ㦂࡛ࡣࠊᘬᙇᙉᗘࢆ⥔ᣢࡋࡘࡘఙࡧࡢྥୖࡀ ほ ࡉࢀ࡚࠾ࡾࠊ㞟ྜ⤌⧊ࡢ⦆࿴࡜㛵㐃ࡀ࠶ࡿ࡜᥎ᐹࡉࢀࡿࠋZW㸣‽⤖ᬗศᩓᮦࡢᘬᙇᙉᗘ ࠾ࡼࡧ ⪏ຊࡣᐊ ࡟࠾࠸࡚ࡣࠊ ࡑࢀࡒࢀ 03Dࠊ03D ࢆ♧ࡋࠊΥ࡛ࡣࡑࢀࡒࢀ 03Dࠊ 03D ࢆ♧ࡋࡓࠋZW㸣࡟࠾ࡅࡿᶵᲔ≉ᛶࡢ‽⤖ᬗ㔞౫Ꮡᛶ࡟ࡘ࠸࡚ࠊᐊ ࡛ࡣ኱ࡁ࡞ᕪ ࡣぢࡽࢀ࡞࠿ࡗࡓࡀ Υ࡟࠾࠸࡚ࡣ㢧ⴭ࡛࠶ࡾ ZW࡟࠾࠸࡚ᛴ⃭࡟ᘬᙇᙉᗘࡢྥୖࡀぢࡽࢀ ࡓࠋ 㠀ᖹ⾮┦ࢼࣀྜ㔠⢏Ꮚࡢ๰〇 ᮏᖺᗘࡢࢺࣆࢵࢡ࡜ࡋ࡚ࡣࠊAl ᇶ㸱ඖ㔠ᒓ㛫໬ྜ≀㸦Al-X-Y㸧ࢆ๓㥑≀㉁࡜ࡋ࡚࢔ࣝ࢝ࣜᛶỈ⁐ᾮ ࡛㑅ᢥⓗ⁐ฟฎ⌮㸦࣮ࣜࢳࣥࢢ㸸leaching㸧ࢆ⾜࠺࡜ࠊ୺⤌ᡂ࡛࠶ࡿ Al ࡀ㑅ᢥⓗ࡟⁐ฟࡋࠊṧࡾࡢ㸰 ඖ⣲㸦X-Y㸧ࡢ㛫࡟ᚑ᮶ࡢᾮయᛴ෭ἲ࡛ࡣᐇ⌧࡛ࡁ࡞࠸㠀ᖹ⾮┦ࡢࢼࣀྜ㔠⢏Ꮚࡀ๰〇࡛ࡁࡿ࡜࠸࠺᪂. (c). (a). (b). (d). 3f 2f. Mg QC. 5-f. 20m ᅗ㸰 =Q0J=U ‽⤖ᬗࡢ⢊ᮎ ; ⥺ᅇᢡ D

(21) ࡜㟁Ꮚ⥺ᅇᢡ E

(22) ᅗᙧ‽⤖ᬗศᩓ 0J ྜ㔠ࡢ 6(0 ീ F

(23) ࡜ࡑࡢ୰ࡢ‽⤖ᬗ⢏Ꮚࡢ㟁Ꮚ⥺ᚋ᪉ᩓ஘ᅇᢡീ G

(24) .

(25) 9. 研究活動報告. ࡋ࠸ㄪ〇ἲࢆ㛤Ⓨࡋࡓࡇ࡜࡛࠶ࡿࠋ ᚑ᮶ࠊྜ㔠ࡢ㠀ᖹ⾮┦ࡢస〇࡟ࡣࠊࢫࣃࢵࢱ࣮➼ࡢẼ┦ἲࡸᾮయᛴ෭ἲ࡟௦⾲ࡉࢀࡿᡭἲࡀ⏝࠸ࡽ ࢀ࡚࠸ࡿࠋẼ┦ἲ࡛ࡣࠊ࢚ࢿࣝࢠ࣮ࡢ㧗࠸㠀ᖹ⾮≧ែࡢ㐩ᡂࡀᮇᚅࡉࢀࡿࡀࠊヨᩱࡢᆒ୍ᛶࠊ෌⌧ᛶ ࡑࡋ࡚Ṍ␃ࡲࡾࡀஈࡋ࠸ࡓࡵ࡟ࠊᐇ⏝ᮦᩱ࡬ࡢᒎ㛤ࡣࡶ࡜ࡼࡾ≀⌮࣭໬Ꮫᛶ㉁ࡢᐃ㔞ⓗ࡞ゎ᫂ࡍࡽᅔ 㞴࡛࠶ࡿࠋ୍᪉ࠊᾮయᛴ෭ἲ࡛ࡣࠊヨᩱࡢ㔞ⓗ࡟ࡣ᭷฼࡛࠶ࡿࡀྜ㔠ࡢ㠀ᖹ⾮≧ែࡢᐇ⌧࡟㝈⏺ࡀ࠶ ࡿࠋຍ࠼࡚ከࡃࡢྜ㔠࡟ࡣᘏᛶࢆ᭷ࡋࠊ⢊○ຍᕤࢆ᪋ࡋ࡚ࡶࡏ࠸ࡐ࠸࣑ࢡ࣮ࣟࣥ࢜ࢲ࣮ࡢ⢏Ꮚࡋ࠿ᚓ ࡽࢀ࡞࠸ࠋ ୍᪉ࠊᮏ◊✲࡛㛤Ⓨࡋࡓ᪉ἲࡣࠊᅗ㸯࡟♧ࡍࡼ࠺࡟ Al ⣔㸱ඖ㔠ᒓ㛫໬ྜ≀࠿ࡽ Al ࢆᢤࡁྲྀࡿࡇ࡜ ࡛ㄏⓎࡉࢀࡿཎᏊ㛫ࡢ෌㓄ิ㸦㠀ᖹ⾮┦ࡢᙧᡂ㸧ࢆ฼⏝ࡍࡿࡶࡢ࡛࠶ࡿࠋࡇࡢ᪉ἲࡣࠊAl ཎᏊࡀ⁐ฟ ࡍࡿࡇ࡜࡛ṧࡉࢀࡓ㸰✀㢮ࡢᵓᡂཎᏊࡀ㧗࠸㓄⨨࢚ࣥࢺࣟࣆ࣮≧ែ࡟࡞ࡿࡓࡵࠊཎᏊ෌㓄ิࡢ㝿࡟㠀 ᖹ⾮≧ែࢆᙧᡂࡍࡿࡇ࡜ࡀ࡛ࡁࡿࠋࡑࡢࡓࡵࠊࡇࡢᡭἲ࡛ࡣᚑ᮶ࡢ⁐ゎἲ࡛ࡣస〇࡛ࡁ࡞࠿ࡗࡓ㠀ᖹ ⾮┦ྜ㔠ࢆᐜ᫆࡟ㄪ〇࡛ࡁࡿࠋ ྛ✀ Al-Cu-Ir㸱ඖ⣔㔠ᒓ㛫໬ྜ≀ࢆ NaOH Ỉ⁐ᾮ࡛࣮ࣜࢳࣥࢢࡍࡿ࡜ࠊ࠸ࡎࢀࡢሙྜ࡟ࡶ Al ࡀ㑅ᢥ ⓗ࡟⁐ฟࡋࠊXRD ᐃ࡟࠾࠸࡚ẕ┦ྜ㔠ࡢᵓ㐀ࣃࢱ࣮ࣥࡣ᏶඲࡟ᾘኻࡋࠊࣈ࣮ࣟࢻ࡞ FCC ᵓ㐀ࣃࢱ࣮ ࣥࡀ⌧ࢀࡿ㸦ᅗ㸰㸧ࠋࡇࡢ⤖ᯝࡣࠊAl ⁐ฟᚋᮏ᮶㠀ᅛ⁐࡛࠶ࡿ Cu ࡜ Ir ࡀᅛ⁐యࢆᙧᡂࡋ࡚࠸ࡿࡇ࡜ ࢆ♧ࡋ࡚࠸ࡿࠋ≉࡟ࠊCu ࡢ⤌ᡂẚ⋡ࡀ኱ࡁࡃ࡞ࡿ࡟ᚑ࠸ᅇᢡࣆ࣮ࢡࡀ㧗ゅᗘഃ࡟ࢩࣇࢺࡋ࡚࠸ࡿࡇ࡜ ࠿ࡽࡶᅛ⁐యᙧᡂࡀ☜ㄆ࡛ࡁࡓࠋ௒ᚋࠊࡇࢀࡽ㐣㣬࿴ᅛ⁐య Cu-Ir ࢼࣀ⢏Ꮚࡢゐ፹≉ᛶ࡞࡝ࢆヲ⣽࡟ㄪ ࡭ࡿணᐃ࡛࠶ࡿࠋ Al-X-Y䠏ඖྜ㔠㠀ᖹ⾮┦X-Yྜ㔠 Leaching Al X Y ᅗ㸱 X-Y 㠀ᖹ⾮ྜ㔠స〇ࡢᴫᛕᅗ ᅗ㸲 Al-Cu-Ir 㔠ᒓ㛫໬ྜ≀ࡢ leaching ᚋ⢊ᮎ X ⥺ᅇᢡᅗᙧ. ྜ㔠⣔ 0J&G5( 5(ᕼᅵ㢮ඖ⣲

(26) ࡟࠾ࡅࡿ㹊㹟㹴㹣㹱┦ࡢᵓ㐀࡜Ᏻᐃᛶ ṇ஧༑㠃య‽⤖ᬗࢆᙧᡂࡍࡿከࡃࡢᕼᅵ㢮ྜ㔠(RE)࡟࠾࠸࡚ࠊMg ࡀᵓ㐀Ᏻᐃ໬ඖ⣲࡜ࡋ࡚㔜せ࡞ ᙺ๭ࢆᯝࡓࡋ࡚࠸ࡿࠋ౛࠼ࡤࠊCd-RE ஧ඖ⣔࡟࠾࠸࡚ࡣ RE=Yb ࡢሙྜ࡟ࡢࡳ‽⤖ᬗࡀᙧᡂࡋࠊ௚ࡢ RE ࡟ᑐࡋ࡚ࡣ‽⤖ᬗࡀᙧᡂࡋ࡞࠸ࡀࠊCd ࡢ୍㒊ࢆ Mg ࡛⨨᥮ࡍࡿࡇ࡜࡛ Y,Ho,Gd,Tb,Dy,Er ➼ከࡃ ࡢ RE ࡟ᑐࡋ࡚‽⤖ᬗࡀᙧᡂࡍࡿࡼ࠺࡟࡞ࡿࠋࡋ࠿ࡋࠊMg ࡟ࡼࡿ‽⤖ᬗࡢᏳᐃ໬ࡢせᅉࡣ᫂ࡽ࠿࡛ࡣ ࡞ࡃࠊཎᏊᵓ㐀࡟ᇶ࡙ࡃࡼࡾヲ⣽࡞᳨ウࡀᚲせ࡛࠶ࡿࠋ ᭱㏆ࠊ୺せ࡞‽⤖ᬗࡢᇶᮏᵓ㐀ࣘࢽࢵࢺࡀゎ᫂ࡉࢀ[Takakura ࡽ, Nature Materials 6, 58 (2007)]ࠊ Ᏻᐃᛶ࡟㛵ࡋ࡚ᵓ㐀ⓗ▱ぢ࡟ᇶ࡙࠸ࡓ㆟ㄽࡀྍ⬟࡜࡞ࡗ࡚ࡁࡓࠋ≉࡟ࠊMg-Cd-RE ⣔‽⤖ᬗ࡟࠾࠸࡚ ࡣࠊṇ 20 㠃యࢡࣛࢫࢱ㛫࡟⏕ࡌࡿ㝽㛫ࡀୗᅗᕥ࡟♧ࡋࡓ⳻ᙧභ㠃యࣘࢽࢵࢺ(㡬Ⅼཬࡧྛ㎶ࡢ୰ᚰ࡟ (Mg,Cd)ࡀࠊෆ㒊ࡢ㛗㍈ୖ࡟ 2 ಶࡢ㹐㹃ࡀ㓄⨨ࡋࡓࡶࡢ)࡟ࡼࡾ༨ࡵࡽࢀࡿࠋMg ࡢῧຍࡣࡇࡢࣘࢽࢵ ࢺࢆᏳᐃ໬ࡉࡏࡿຠᯝࡀ࠶ࡾࠊࡑࢀࡀ‽⤖ᬗࡢᙧᡂ࡜ᐦ᥋࡟㛵ಀࡍࡿ࡜᥎ ࡉࢀࡿࡀヲ⣽ࡣ᫂ࡽ࠿࡛ ࡣ࡞࠸ࠋᮏ◊✲ࡢ┠ⓗࡣࠊ⳻ᙧභ㠃యࣘࢽࢵࢺࡢᏳᐃᛶࡀ Mg ࡢ⤌ᡂ⋡࡟ࡼࡾ࡝ࡢࡼ࠺࡟ኚ໬ࡍࡿ࠿ ࢆㄪ࡭ࠊ‽⤖ᬗࡢᏳᐃᛶ࡟࠾ࡅࡿ㹋㹥ࡢᙺ๭ࢆ≀⌮ⓗ࡟⌮ゎࡍࡿࡇ࡜࡛࠶ࡿࠋࡑࡢⅭ࡟ࠊ⳻ᙧභ㠃య ࣘࢽࢵࢺࡢ࿘ᮇ㓄ิࢆᣢࡘ⤖ᬗ┦㸦㹊㹟㹴㹣㹱┦㸧࡟╔┠ࡋࠊࡑࡢ⤌ᡂ࡜Ᏻᐃᛶࡢ㛵ಀࢆᐇ㦂ⓗ࡟ヲ ⣽࡟ㄪ࡭ࡓࠋୗᅗྑ࡟භ᪉ᬗ㹊㹟㹴㹣㹱┦㸦㹁㸯㸲㸧ࡢ⤖ᬗᵓ㐀㸦(100)᪉ྥࡢᢞᙳᅗ㸧ࢆ♧ࡋࡓࡀࠊ.

(27) 研究活動報告. 㹐㹃ࡀᵓᡂࡍࡿᅄ㓄఩ࢿࢵࢺ࣮࣡ࢡ࡜㹋㹥ཪࡣ㹁㹢ࡀᵓᡂࡍࡿࢿࢵࢺ࣮࣡ࢡ࡜ࡀධࢀᏊᵓ㐀࡜࡞ࡗ࡚ ࠸ࡿࠋCd-RE ཬࡧ Mg-RE ஧ඖ⣔ࡢ≧ែᅗࡣ᪤࡟ከࡃࡀฟ∧ࡉࢀ࡚࠾ࡾࠊ㹊㹟㹴㹣㹱┦㸦භ᪉ᬗ㹁㸯㸲㸪ཬࡧ❧᪉ᬗ㹁㸯㸳ࡢ஧ࡘࡢࢱ࢖ࣉ㸧ࡣ Cd2YbࠊMg2RE(RE=Y,La㹼Lu)࡟࠾࠸࡚ࡢࡳᖹ⾮┦࡜ࡋ࡚ Ꮡᅾࡍࡿࡇ࡜ࡀ▱ࡽࢀ࡚࠸ࡿ㸦ణࡋࠊCe ➼ࡢ୍㒊ࡢ RE ࡟ᑐࡋ࡚ࡣ㧗 ┦࡜ࡋ࡚ࡢࡳᏳᐃ࡛࠶ࡿ㸧 ࠋ. ᮏ◊✲࡛ࡣࠊRE ࡜ࡋ࡚ Ce,Pr,Eu,Gd,Tb,Dy,Ho,Er,Tm,Yb ࢆ⏝࠸ࡓヨᩱ㸦⤌ᡂᘧ(Mg,Cd)2RE㸧ࢆ ᵝࠎ࡞ Mg㸭Cd ⤌ᡂẚ⋡ཬࡧ ᗘ᮲௳࡟ࡼࡾసᡂࡋࡓࠋᚓࡽࢀࡓヨᩱ࡟ᑐࡋ࡚ࠊ⤖ᬗᵓ㐀ྠᐃ㸦⢊ᮎ 㹖⥺ᅇᢡἲ㸧 ࠊ⤌⧊ほᐹ㸦㉮ᰝᆺ㟁Ꮚ㢧ᚤ㙾ἲ㸧ࠊཬࡧ⤌ᡂศᯒ㸦㟁Ꮚ⥺࣐࢖ࢡࣟ࢔ࢼࣛ࢖ࢨ㸧ࢆ⾜࠸ࠊ 㹊㹟㹴㹣㹱┦ࡀᏳᐃ࡜࡞ࡿ⤌ᡂ࣭ ᗘ㡿ᇦࢆㄪ࡭ࡓࠋࡑࡢ⤖ᯝᚓࡽࢀࡓ▱ぢࢆ௨ୗ࡟グࡍࠋ RE=Ce,Pr ࡢሙྜࠊ㹊㹟㹴㹣㹱┦㸦㹁㸯㸳㸧Mg2RE ࡣ㧗 ┦࡜ࡋ࡚ࡢࡳᏳᐃ࡛࠶ࡾࠊᐊ ࡲ࡛෭༷ ࡋࡓ᫬࡟ MgRE ࡜ Mg3RE ࡢ஧┦࡬࡜┦ศ㞳ࢆ㉳ࡇࡍࠋࡋ࠿ࡋࠊMg ࡢ୍㒊ࢆ Cd ࡛⨨᥮ࡋࡓሙྜ㸦㸮㹼㸯㸮at㸣㸧 ࠊᐊ ࡟࠾࠸࡚ࡶ㹊㹟㹴㹣㹱┦ࡀᏳᐃ໬ࡉࢀࡿࠋࡇࢀࡣࠊ㹁㸯㸳ࢱ࢖ࣉࡢ㹊㹟㹴㹣㹱┦ࢆ ᙧᡂࡍࡿ RE ⣔ิ๓༙ࡢඖ⣲࡟ඹ㏻ࡍࡿᛶ㉁࡛࠶ࡿࠋRE=Eu,Tb,Dy,Ho,Er,Tm ࡢሙྜࠊ㹊㹟㹴㹣㹱┦ 㸦㹁㸯4㸧Mg2RE ࡀᐊ ࡛Ᏻᐃ┦࡛࠶ࡿࠋMg ࡢ୍㒊ࢆ Cd ࡛⨨᥮ࡋࡓሙྜࠊEu ࡟ᑐࡋ࡚ࡣ㸮㹼㸳㸮 at㸣⛬ᗘࠊTb㹼Tm ࡟ᑐࡋ࡚ࡣ㸮㹼㸯㸮at㸣⛬ᗘࡢ㹁㹢⤌ᡂࡲ࡛ࡣ㹊㹟㹴㹣㹱┦ࡢᏳᐃᛶࡀಖᣢࡉࢀ ࡿࠋRE=Gd ࡢሙྜࠊMg ẚ⋡ࡀ㸮㹼㸯㸮at㸣࡟࠾࠸࡚ࠊ㹁㸯㸲࡜㹁㸯㸳ࡢ஧ࢱ࢖ࣉࡢ Laves ┦ࡀඹᏑ ࡋ࡚ほᐹࡉࢀࡓࠋࡇࢀࡣࠊGd ࡀ RE ⣔ิ࡟࠾࠸࡚㹊㹟㹴㹣㹱┦ࡢࢱ࢖ࣉࡀ㹁㸯㸳࠿ࡽ㹁㸯㸲࡟ኚ໬ࡍ ࡿቃ⏺࡟┦ᙜࡍࡿࡓࡵ࡛࠶ࡿࠋ㹊㹟㹴㹣㹱┦ࡀ୙Ᏻᐃ໬ࡉࢀࡿ㹁㹢ࡢ㔞ࡣ RE ࡢ✀㢮࡟౫ᏑࡍࡿࠋRE= 㹗㹠ࡢሙྜࠊ㹊㹟㹴㹣㹱┦㸦㹁㸯4㸧ࡣ Mg2Yb ࠿ࡽ Cd2Yb ࡲ࡛ࡢ඲㡿ᇦ࡛Ᏻᐃ㸦ᐊ 㸧࡛࠶ࡾࠊMg ࡢẚ⋡ࡢቑ኱࡜࡜ࡶ࡟᱁Ꮚᐃᩘࡀ㐃⥆ⓗ࡟ቑ኱ࡍࡿࠋ௨ୖࢆࡲ࡜ࡵࡿ࡜ࠊ(Mg,Cd)2RE ࡟࠾ࡅࡿ Mg-rich ࡞㡿ᇦ࡛ࡣ㹊㹟㹴㹣㹱┦ࡢᏳᐃᛶࡣ㹁㹢ࡢᏑᅾୗ࡛ࡶಖᣢࡉࢀࡿࠋ≉࡟ࠊ஧౯ࡢ RE ࡛࠶ࡿ Eu ࡜ Yb ࡟ᑐࡋ࡚ࡣࠊ௚ࡢ RE ࡟ẚ࡭࡚㹊㹟㹴㹣㹱┦ࡢᏳᐃ⤌ᡂ㡿ᇦࡀ᱁ẁ࡟ᗈ࠸ࠋࡲࡓࠊRE=Ce,Pr ࡟ᑐࡋ࡚ࡣࠊCd ࡢᏑᅾࡀ㹊㹟㹴㹣㹱┦ࡢᏳᐃᛶࢆಁ㐍ࡍࡿຠᯝࡀ࠶ࡿࠋ Mg-rich ࡞⤌ᡂᇦ࡛ᙧᡂࡍࡿ㹊㹟㹴㹣㹱┦࡟ᑐࡋ࡚ヲ⣽࡞⤌ᡂศᯒࢆ⾜ࡗࡓ࡜ࡇࢁࠊ඲࡚ࡢ㹐㹃࡟ ᑐࡋ࡚㹊㹟㹴㹣㹱┦ࡢ⤌ᡂࡀ(Mg,Cd)67+xRE33-x (x=5㹼10at㸣)⛬ᗘ࡜࡞ࡗ࡚࠾ࡾࠊ⤌ᡂᘧ (Mg,Cd)2RE ࠿ࡽ᭷ព࡞ࡎࢀࢆ♧ࡋ࡚࠸ࡿࡇ࡜ࡀศ࠿ࡗࡓࠋࡇࢀࡣ㹁㹢ࢆῧຍࡋ࡞࠸ Mg2RE ࡟࠾࠸࡚ࡶ෌⌧ᛶⰋࡃ ほᐹࡉࢀࠊ᪤Ꮡࡢ Mg-RE ≧ែᅗࡢ෌᳨ウࢆಁࡍ⯆࿡῝࠸⤖ᯝ࡜࡞ࡗࡓࠋࡇࢀࡣࠊ୍㒊ࡢ RE ࢧ࢖ࢺࡀ Mg ࡟ࡼࡾ⨨᥮ࡉࢀ࡚࠸ࡿࡇ࡜ࢆ♧၀ࡋ࡚࠸ࡿࡀࠊྠᵝ࡞ RE ࡢᕼ㔘໬ࡣ Mg-Cd-RE ⣔‽⤖ᬗ࡟࠾࠸ ࡚ࡶほᐹࡉࢀ࡚࠾ࡾࠊMg ࡟ࡼࡿᵓ㐀Ᏻᐃ໬ຠᯝ࡜ᐦ᥋࡟㛵ಀࡋࡓ⯆࿡῝࠸⌧㇟࡜ᛮࢃࢀࡿࠋ௒ᚋࠊࡉ ࡽ࡟ヲ⣽࡟ㄪᰝࢆ⾜࠺ᚲせࡀ࠶ࡿࠋ. 10.

(28) 11. 研究活動報告. ⏕యᶵ⬟タィ◊✲ศ㔝䠄2009䠊1䡚2009䠊12䠅㻌. 䛆◊✲άືሗ࿌䛇㻌㻌 ᩍ ෸. ᩍ. ᤵ㻌㻦ୗᮧ㻌 ᨻႹ㻌 ᤵ㻌㻦⏣୰㻌㈼㻌. ຓ ᩍ㻌㻦⸭㻌 ᾈ㻘▼஭㻌 ኱భ䠄㼃㻼㻵䠅㻌 ຓ ᡭ㻌㻦ᵽཱྀ㻌 ๛ᚿ䠄㼃㻼㻵䠅㻌 ኱ Ꮫ 㝔 ⏕㻌㻦ඣᓥ㻌 ⨾Ꮨ㻘ᖹ஭㻌 ᝆྖ㻘Ⲩ㻌㞞ᾈ㻘ᮏྜྷ㻌 ✲㻘ᑠụ㻌 ࿴Ꮥ㻘㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌 ୰す㻌㈗அ㻘௰㐨㻌 ⿱㈗㻌 Ꮫ 㒊 Ꮫ ⏕㻌㻦㐲⸨㻌 ᙬᏊ㻘㧗ᶫ㻌 ❶ோ㻌㻌. ᮏ◊✲ศ㔝䛷䛿䠈⮬ᕫ⤌⧊໬䝋䝣䝖䝬䝔䝸䜰䝹䛾స〇䛸ᶵ⬟䛻䛴䛔䛶◊✲άື䜢⾜䛳䛶䛔䜛䠊㻞㻜㻜㻥 ᖺ䛾◊ ✲άື䛸䛧䛶䛿䠈௨ୗ䛾䜘䛖䛻ᴫᣓ䛥䜜䜛䠊㻌㻌㻝㻚㻌 ⮬ᕫ⤌⧊໬䝝䝙䜹䝮䝣䜱䝹䝮䛸䛭䛾ᛂ⏝䛻㛵䛩䜛◊✲㻌䝫䝸䝬䞊⁐ᾮ䜢㧗‵ᗘୗ䛷ሬᕸ䞉〇⭷䛩䜛ㄢ⛬䛷䚸✵Ẽ୰䛛䜙⤖㟢䛧䛯Ỉ⁲䜢㗪ᆺ䛸䛧䛶䝝䝙䜹䝮≧䛻✵Ꮝ 䛜✸䛯䜜䛯ከᏍ㉁⭷䠄䝝䝙䜹䝮䝣䜱䝹䝮䠅䛜ᚓ䜙䜜䜛஦䜢ぢ䛔䛰䛧䛶䛔䜛䚹䛣䜜䜎䛷䛻䝝䝙䜹䝮䝣䜱䝹䝮䛾⏕⏘ ᢏ⾡䛚䜘䜃䛭䛾ᛂ⏝᳨ウ䜢⾜䛳䛶䛝䛯䚹ᮏ◊✲䛷䛿䚸୙ᆒ୍ᛶ䛸䛔䛖⮬ᕫ⤌⧊໬䛾ḞⅬ䜢ඞ᭹䛧䛯䝝䝙䜹䝮 ⭷䜢ฟⓎᮦᩱ䛸䛧䚸䛭䛣䛻⮬ᕫ⤌⧊໬䛾୙ᆒ୍ᛶ䜢ά⏝䛩䜛䛣䛸䛷䚸↓㟁ゎ䜑䛳䛝䛻䜘䜛㔠ᒓᯒฟ㔞䛾໙㓄䜢 ពᅗⓗ䛻䛴䛟䜚䛰䛧䚸ྠ୍ᇶᯈୖ䛷㐃⥆ⓗ䛻᧕Ỉᛶ䜔Ỉ⁲྾╔ᛶ➼䛾䛼䜜≉ᛶ䛜␗䛺䜛⾲㠃䜢స〇䛧䛯䚹䝝䝙䜹䝮⭷䜢↓㟁ゎ䜑䛳䛝䛾ゐ፹᰾䛷䛒䜛䝟䝷䝆䜴䝮䛾㓄఩䛧䛯Ỉ⁐ᛶ㧗ศᏊ䛾ᕼⷧ⁐ᾮ䠄㻞㻡ࠥ㻢㻜䉝䠅䛻䚸ᆶ┤ 䛻㻡㻜ࠥ㻝㻡㻜㻜μ㼙㻛㼟䛾㏿ᗘ䛷ᾐₕ䛧䚸䛭䛾ᚋ䚸↓㟁ゎ䝙䝑䜿䝹䜑䛳䛝䛩䜛䛣䛸䛷䚸䝙䝑䜿䝹⿕そ䝝䝙䜹䝮⭷䜢ᚓ䛯 ᚓ䜙䜜䛯⭷䛾ᯒฟ㔠ᒓ㠃䜢䜰䜽䝸䝹ᯈ䛻䜶䝫䜻䝅ᶞ⬡䛷ᅛᐃ䛧䚸䝝䝙䜹䝮⭷䜢๤㞳ฎ⌮ 㻞㻕䜢䛩䜛䛸䚸ᅗ 㻝䛻♧ 䛩䜘䛖䛺㔠ᒓ䝗䞊䝮䛸㧗ศᏊ䝢䝷䞊䛾䝝䜲䝤䝸䝑䝗ᵓ㐀䛜ᚓ䜙䜜䛯䚹㻌. 㻌 ᅗ䠍䠊㔠ᒓ䝗䞊䝮䛸㧗ศᏊ䝢䝷䞊䛾䝝䜲䝤䝸䝑䝗ᵓ㐀㻌㻌.

(29) 研究活動報告. 㻞㻚㻌䝫䝸䝬䞊ᚤ⢏Ꮚ䛾ෆ㒊ᵓ㐀ไᚚ䛻㛵䛩䜛◊✲㻌㻌䝫䝸䝬䞊䛾⁐ᾮ䛻㈋⁐፹䜢ຍ䛘䚸Ⰻ⁐፹䜢⵨Ⓨ䛥䛫䜛䛣䛸䛻䜘䜚ᚤ⢏Ꮚ໬䛩䜛䛂⮬ᕫ⤌⧊໬ᯒฟ (Self-ORganized Precipitation, SORP)ἲ䛃䜢ぢ䛔䛰䛧䛶䛔䜛䚹ᮏᡭἲ䜢⏝䛔䚸䝤䝻䝑䜽䝁䝫䝸䝬䞊䜔䝫䝸䝬䞊䝤䝺䞁䝗䛺䛹䛛䜙ᚤ⢏Ꮚ䜢స〇䛩䜛䛸䚸ᚤ⢏Ꮚෆ㒊䛻䝘䝜䝇䜿䞊䝹䛾┦ศ㞳ᵓ㐀䛜ᙧᡂ䛥䜜䜛䚹ᚤ⢏Ꮚෆ㒊䛾┦ ศ㞳ᵓ㐀䛻ᚤ⢏Ꮚ䛾⢏ᚄ䛜୚䛘䜛ᙳ㡪䜢ヲ⣽䛻ゎᯒ䛩䜛䛯䜑䛻䚸㏱㐣㟁Ꮚ㢧ᚤ㙾䝖䝰䜾䝷䝣䜱䞊䠄TEMT䠅䜢 ⏝䛔䛶䚸┦ศ㞳ᵓ㐀䛾 3 ḟඖほᐹ䜢⾜䛳䛯䚹䝞ࣝࢡࣇ࢕࣒ࣝ୰࡛࣓ࣛࣛᵓ㐀ࢆᙧᡂࡍࡿ㧗ศᏊ㔞ࡢ Poly(styrene-b-isoprene) (PSt-b-PI, Mn(PSt) = 850,000, Mn(PI) = 700,000, Mw/Mn = 1.15, fPI = 0.58)࠿ࡽ 6253 ἲ࡟ ࡼࡾᚤ⢏Ꮚࢆస〇ࡋࡓࠋᚤ⢏Ꮚస〇ᚋࠊPI ୰ࡢ஧㔜⤖ྜࡢࡳࢆ OsO4 Ỉ⁐ᾮ࡟ࡼࡗ࡚㑅ᢥⓗ࡟ᰁⰍࢆ⾜ ࡗࡓᚋࠊ㏱㐣ᆺ㟁Ꮚ㢧ᚤ㙾㸦TEM㸧ほᐹ࠾ࡼࡧ TEMT ࡟ࡼࡿ 3 ḟඖᵓ㐀ほᐹࢆ⾜ࡗࡓࠋస〇ࡋࡓࣈࣟ ࢵࢡࢥ࣏࣐࣮ࣜᚤ⢏Ꮚࡢ TEM ീࢆᅗ 2 (a)-(f)࡟♧ࡍࠋᅗ୰ࡢᬯ㒊ࡣ OsO4 ࡟ࡼࡾᰁⰍࡉࢀࡓ PI ┦ࢆࠊ᫂ 㒊ࡣ PSt ࢆ♧ࡋ࡚࠸ࡿࠋࡑࢀࡒࢀࡢ⢏Ꮚ࡟ᑐࡋ࡚ TEMT ἲࢆ⏝࠸࡚ 3 ḟඖᵓ㐀ほᐹࢆ⾜ࡗࡓ⤖ᯝࢆᅗ 2 (g)-(r)࡟♧ࡍࠋ㟷Ⰽࡢ 3 ḟඖീࡣྛ⢏Ꮚ୰ࡢ PSt ┦ࢆࠊ⥳Ⰽࡢ 3 ḟඖീࡣ PI ┦ࢆ⾲ࡋ࡚࠸ࡿࠋࡇࢀࡼ ࡾࠊ᭱ࡶ⢏ᚄࡀᑠࡉ࠸⢏Ꮚ୰࡛ࡣ PStࠊPI ┦ࡀࡑࢀࡒࢀ༙⌫≧ࡢࣖࢾࢫᆺᵓ㐀ࢆࠊ⢏ᚄࡀቑ኱ࡍࡿ࡜ PI ┦ࡀ࣐ࢵࢩ࣮࣒ࣗࣝ≧ࡢᵓ㐀㸦ᅗ 2 (j)㸧ࢆᙧᡂࡋ࡚࠸ࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋࡼࡾ⢏ᚄࡀ኱ࡁࡃ ࡞ࡿ࡜ࠊPSt ┦࡜ PI ┦ࡀ┤஺ࡋࡓࢸࢽࢫ࣮࣎ࣝ≧ࡢᵓ㐀ࢆᙧᡂࡋ࡚࠸ࡿࡇ࡜ࡀࢃ࠿ࡗࡓࠋࡉࡽ࡟⢏ᚄ ࡀቑ኱ࡍࡿ࡜ࠊࢸࢽࢫ࣮࣎ࣝ≧ᵓ㐀࡟࠾ࡅࡿᯈ≧ࡢ PI ┦࡟ᨭᰕࡀ 1, 2, 4 ᮏ㸦ᅗ 2 (n), (p), (r)㸧⤖ྜࡋ ࡓ」㞧࡞┦ศ㞳ᵓ㐀ࢆᙧᡂࡋ࡚࠸ࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋ㻌. ᅗ 2. (a)-(f) 䝤䝻䝑䜽䝁䝫䝸䝬䞊ᚤ⢏Ꮚ䛾 TEM ീ䚹PSt ┦䛾୕ḟඖ෌ᵓᡂീ ((g), (i), (k), (m), (o), (q))䛚䜘䜃 PI ┦䛾෌ᵓᡂീ ((h), (j), (l), (n), (p), (r))䚹. 12.

(30) 13. 研究活動報告. 䛆◊✲άືሗ࿌䛇. ≀⌮䝥䝻䝉䝇タィ◊✲ศ㔝㻌. (2009.1㹼2009.12). ᩍ ᤵ㸸㰻⸨ᩥⰋ ෸ ᩍ ᤵ㸸ຍ⣡⣧ஓ㸪ྜྷᕝ ᙲ ຓ ᩍ㸸ᙇ ඼Ṋ㸪㧗ᶫ⣧୍ ᩍ⫱◊✲ᨭ᥼⪅㸸ᰗ⏣೺அ, ᶓ⏣᭷Ⅽ ࣜࢧ࣮ࢳࣇ࢙࣮ࣟ㸸Ⲷ㔝 ᣅ(ᮾ኱)㸪బ⸨ගᾈ(㔝ᮧドๆ) ◊ ✲ ⏕㸸Kouklan Mohammad Hossin(᪥ᮏ࢔࢖ࣜࢵࣄ 2008.12-2009.6) ◊ ✲ ဨ㸸Ώ㑔㣕㫽㸪ᯘ⏣⏤⨾Ꮚ(2008.6-2009.3)㸪㰻⸨ளᕼᏊ(2009.1-5)㸪 బ⸨リ⧊(2009.6-)㸪Kanatip Kumproa(2008.9-2009.2)㸪Guillaume N. Lefebvre (2009.6-2009.8)㸪Jan Pejchal, Valery Chani (2009.10-)㸪๓ᑿ ಟ ྖ (2009.4-) 㸪 Mariya Zhuravleva (-2009.2), Moretti Federico (2009.4-8) Ẹ㛫➼ඹྠ◊✲ဨ㸸⚟⏣೺ኴ㑻(㺢㺖㺲㺭)㸪Ἑཱྀ⠊᫂(㺢㺖㺲㺭)㸪㙊⏣ ᆂ(ྂἙᶵᲔ㔠ᒓ)㸪 ᡞሯ኱㍜(᪥ᮏ⤖ᬗගᏛ 2009.9-) ኱ Ꮫ 㝔 ⏕㸸῝ᇼ᫂༤(D2)㸪᭮⏣ຊኸ(D1)㸪⸨ᮏ⿱(D1)㸪㜿㒊┤ே(M2)㸪ඵᮌ ᆂு(M1)㸪⏣୰⚽ᙪ(M1)㸪ྂ㇂ඃ㈗(M1) Ꮫ 㒊 Ꮫ ⏕㸸▼ཎ┿࿃(B4)㸪ෆᒣ࿴๎(B4)㸪㧗ぢ⃝⚽ᶞ(B3) ᢏ⾡⿵బဨ㸸ᡞཱྀᬒᏊ㸪Ḉ஭⨾㔛(2009.9-) ஦ົ⿵బဨ㸸すᮧᩥ⥴㸪ᮌᮧ⨾ಖ(-2009.8)㸪㙊⏣༓⛅(-2009.8)㸪ᩧ⸨ⰼዉ(-2009.3) ୖᮧ༤(2009.7-)௒஭ளᕼᏊ(2009.5-) ᣍ ⪸ ᩍ ᤵ㸸Georges Boulon(ࣜࣚࣥ኱), Martin Nikl(ࢳ࢙ࢥ≀⌮◊), Vladimir V. Kochurikhin(ࣟࢩ࢔≀⌮◊) ᙜ◊✲ࢢ࣮ࣝࣉࡢ2009ᖺ1㹼12᭶ࡲ࡛ࡢ◊✲άືࡢᴫせࡣ௨ୗࡢ㏻ࡾ࡛࠶ࡿ㸬㸯㸬࣓࢝ࣀࢣ࣑ࢫࢺ࣮ࣜࢆ฼⏝ࡋࡓ⣲ᮦ࣭ᮦᩱ࡜ࣉࣟࢭࢫ㛤Ⓨ ⦆ຠᛶ⫧ᩱࡢྜᡂ ໬Ꮫ⫧ᩱࡢࣜࣥ㓟࣒࢝ࣜ࢘ࡸࣜࣥ㓟࢔ࣔࣥࢽ࣒࢘ࡣ㔜せ࡞⫧ᩱᡂศ࡛࠶ࡿࡀ㸪㝆㞵࡟㝿ࡋ㸪ᐜ᫆࡟ ⁐ゎࡍࡿࡢ࡛ᅵተ࡟ṧ␃ࡋ࡞࠸࡜࠸࠺ၥ㢟Ⅼࡀ࠶ࡿ㸬ඃࢀࡓᶵ⬟ࢆ᭷ࡍࡿ⫧ᩱࢆస〇ࡍࡿ࡟ࡣỈ⁐ᛶ ࡢᢚไࡀᚲせ࡛࠶ࡾ㸪ࡑࡢࡓࡵ࡟ࡣ㸪ᅵ࡟ྵࡲࢀ࡚࠸ࡿ↓ᶵ㓟໬≀࡜ࡢ㐺ษ࡞ᙧែࡢ໬ྜ≀࡟ࡍࡿࡇ ࡜ࡀ㘽࡜࡞ࡿ㸬ᮏ◊✲࡛ࡣ㸪࣓࢝ࣀࢣ࣑࢝ࣝฎ⌮ࢆ฼⏝ࡋୖグ⫧ᩱᡂศࢆ㞴Ỉ⁐ᛶ(⦆ຠᛶ)࡟ࡍࡿ◊ ✲ࢆ㐍ࡵ࡚࠸ࡿ㸬⌧ᅾ௻ᴗ࡜ࡢඹྠ◊✲࡬࡜Ⓨᒎࡋ㸪ࣜࣥ㓟ሷ௨እࡢ⫧ᩱ࡬ࡢᛂ⏝࡞࡝㸪ᐇ⏝໬࡬ࡢ ྍ⬟ᛶࢆ☜ㄆࡋ࡚࠸ࡿ㸬㓟໬ள㖄⣔ගゐ፹ࡢㄪ〇 ZnO ࡟ N ࡸ C ࢆࢻ࣮ࣆࣥࢢࡋ㸪ྍどගᛂ⟅ᛶගゐ፹ㄪᩚࢆヨࡳ࡚࠸ࡿ㸬ࢻ࣮ࣆࣥࢢࡣ㸪࣓࢝ࣀࢣ ࣑࢝ࣝฎ⌮࡛⾜࠸㸪⢊○ሙࡢ㞺ᅖẼ࢞ࢫ✀(N2 ࡸ NH3 ࡞࡝)࡜ࡑࡢᅽຊࢆไᚚࡋ㸪⏕ᡂ≀ࡢᶵ⬟ࢆホ౯ ࡋ࡚࠸ࡿ㸬ᮏ◊✲ࡣ㸪ඛ࡟ᐇ᪋ࡋࡓ TiO2 ࡬ࡢ㠀㔠ᒓඖ⣲ࢻ࣮ࣆࣥࢢࡢ⤖ᯝࢆཧ⪃࡟㸪ZnO ࡬ࡢῧຍ ᮦ࡜ࡋ࡚Ⅳ㓟࢔ࣥࣔࢽ࣒࢘ࡸ࢚ࢱࣀ࣮ࣝࢆ㑅ᢥࡋ㸪✀ࠎࡢ⢊○᮲௳࡛┠ⓗ≀㉁ࢆྜᡂࡋ㸪ࡑࡢගゐ፹ ≉ᛶࢆㄪᰝࡋ࡚࠸ࡿ㸬.

(31) 研究活動報告. ࣂ࢖࣐࢜ࢫ࠿ࡽࡢ㧗⣧ᗘỈ⣲࢞ࢫⓎ⏕ ࣏ࣜሷ໬ࣅࢽࣝ(PVC)ࡸࢭ࣮ࣝࣟࢫ(ᮌᮦࢳࢵࣉ࡞࡝)࡟↓ᶵ≀㸪ゐ፹ࢆῧຍࡋ࡚஝ᘧ⢊○(࣓࢝ࣀࢣ ࣑࢝ࣝฎ⌮)ࡋ㸪ࡑࡢᚋ⢊○⏘≀ࢆຍ⇕ࡍࡿ࡜㸪㧗⣧ᗘỈ⣲ࡀⓎ⏕ࡍࡿࡇ࡜ࢆぢฟࡋࡓ㸬ᮏᖺᗘࡣ㸪ຍ ⇕㐣⛬࡛ࡢヨᩱࡢ⇕ศゎ᫬ࡢỈ⣲Ⓨ⏕ᶵᵓࢆ᫂☜࡟ࡍࡿ◊✲ࢆ୰ᚰ࡟㸪ゐ፹ᶵ⬟ࢆᣢࡘ Ni(OH)2 ࡢศ ᩓຠᯝ㸪ῧຍ≀࡜ゐ፹࡜ࡢ」ྜ໬࡟ࡼࡿỈ⣲Ⓨ⏕㔞➼ࢆ᳨ウࡋ㸪ຠ⋡ࡼ࠸Ỉ⣲Ⓨ⏕᮲௳ࢆぢฟࡍ◊✲ ࢆ㐍ࡵ࡚࠸ࡿ㸬 ┤᥋㑏ඖἲ࡟ࡼࡾᕼᑡ㔠ᒓ㓟໬≀࠿ࡽࡢᕼᑡ㔠ᒓᅇ཰ 㓟໬࢖ࣥࢪ࣒࢘㸪㓟໬ࢫࢬ㸪㓟໬ࢱࣥࢢࢫࢸࣥ࡞࡝ࡢ㓟໬≀࡟ᑐࡋ࡚❅໬ࣜࢳ࣒࢘ࢆῧຍࡋ㸪㞺ᅖ Ẽࢆㄪᩚࡋ࡚⢊○(࣓࢝ࣀࢣ࣑࢝ࣝฎ⌮)ࡍࡿ࡜㸪㓟໬≀ࡣ㑏ඖࡉࢀ࡚㔠ᒓࡀᚓࡽࢀࡿࡇ࡜ࢆぢฟࡋ࡚࠸ ࡿ㸬ࡇࡢ᪉ἲ࡟ࡼࡿ࡜㸪ITO࠿ࡽࡢ࢖ࣥࢪ࣒࢘ࡢᅇ཰࡞࡝㸪ᕼᑡ㔠ᒓ㓟໬≀ࢆྵࡴᗫᲠ≀࠿ࡽᕼᑡ㔠ᒓ ࢆ┤᥋ᅇ཰ࡍࡿࡇ࡜ࡀ࡛ࡁࡿ㸬ᮏᖺᗘࡣ㸪≉࡟ᾮᬗࣃࢿࣝ࠿ࡽࡼࡾຠ⋡ࡼࡃ࢖ࣥࢪ࣒࢘ࢆᅇ཰ࡍࡿࡓ ࡵࡢᡭἲ㛤Ⓨ㸪᮲௳タᐃ➼࡟ࡘ࠸᳨࡚ウࡋ㸪ᡂᯝࢆᣲࡆ࡚࠸ࡿ㸬ࡲࡓ㸪ࢿ࢜ࢪ࣒☢▼࠿ࡽࢿ࢜ࢪ࣒㸪 ࢪࢫࣉࣟࢩ࣒࢘ࡢᅇ཰ࡢྍ⬟ᛶࢆ㏣ồࡋ࡚࠸ࡿ㸬㸰㸬࣑ࣝෆ፹య㐠ືࡢ'(0ࢩ࣑࣮ࣗࣞࢩࣙࣥἲᵓ⠏࡜ྛ✀⢊య⿦⨨ෆ࡛ࡢ⢊⢏యࡢ㐠ື➼ࡢᢕᥱ ⢊○ᶵෆ፹య㐠ືࡢᢕᥱ࡜⏘≀ࡢ⢏Ꮚᚄศᕸ㸪࣑ࣝᾘ㈝㟁ຊࡢண 㞳ᩓせ⣲ἲ(DEM)࡟ࡼࡿ3ḟඖⓗ⢏Ꮚ⩌㐠ືࡢࢩ࣑࣮ࣗࣞࢩࣙࣥࢆ‵ᘧ፹యᆺ⢊○ᶵෆࡢ፹య㐠ື ࡢᢕᥱ࡟㐺⏝ࡋ㸪ࡑࡢ㐠ືࢆⰋዲ࡟෌⌧ࡍࡿࡇ࡜࡟ᡂຌࡋࡓ㸬፹య㐠ືࡣ⢊○⏘≀ࡢ⢏Ꮚᚄศᕸ㸪ᦶ ⪖⌧㇟㸪࣑ࣝᾘ㈝㟁ຊ࡟ᐦ᥋࡟㛵㐃ࡋ㸪ࡑࢀࡽࢆࢩ࣑࣮ࣗࣞࢩࣙࣥ᝟ሗ࠿ࡽண ࡍࡿࡇ࡜ࢆヨࡳ࡚࠸ ࡿ㸬ᮏᖺᗘࡣ㸪ࢩ࣑࣮ࣗࣞࢩࣙࣥ࡟ࡼࡗ࡚‵ᘧ፹య᧠ᢾ࣑ࣝ⢊○࡟࠾ࡅࡿ⏘≀ࡢ⢏Ꮚᚄศᕸࡸᾘ㈝㟁 ຊࡀண ྍ⬟࡛࠶ࡿࡇ࡜ࢆ♧ࡋࡓ㸬ࡲࡓ㸪⢊○㐣⛬࡛ࡢᦶ⪖⢊ΰධࡢ࣓࢝ࢽࢬ࣒ࢆᐇ㦂ⓗ࡟᫂☜࡟ࡋ㸪 ࡑࡢ᝟ሗ࡜ࢩ࣑࣮ࣗࣞࢩࣙࣥ࠿ࡽࡢ፹య㐠ື᝟ሗࢆ⼥ྜࡋ࡚㸪ᦶ᧿௙஦ࢆ⟬ฟࡋ㸪ᦶ᧿௙஦ࡸᦶ⪖⢊ ΰධ㔞࡜ࡢ┦㛵㛵ಀࢆ᫂☜࡟ࡋ࡚ᦶ⪖⢊ΰධ㔞ࡀண ྍ⬟࡛࠶ࡿࡇ࡜ࢆ♧ࡋࡓ㸬 ─ᆺ㐀⢏ᶵ࡟࠾ࡅࡿᚤ⢊యࡢ㐀⢏㐣⛬࣭ᶵᵓࡢᢕᥱ ─ᆺ㐀⢏ᶵࡣ㕲㖔▼⢊యࡢሢᡂ໬࡞࡝࡛ከ⏝ࡉࢀ࡚࠸ࡿࡀ㸪ᡤᮃࡍࡿ㐀⢏యࢧ࢖ࢬࢆᚓࡿᬑ㐢ⓗ࡞ ᮲௳タᐃ᪉ἲࡀ࡞ࡃ㸪ࡇࢀࡀࡑࡢᚋࡢ↝ᡂࣉࣟࢭࢫࡢ᭱㐺໬ࢆ㜼ᐖࡍࡿせᅉࡢ୍ࡘ࡜࡞ࡗ࡚࠸ࡿ㸬ᮏ ◊✲࡛ࡣ㸪ࣃࣥᆺ㐀⢏ᶵ࡟ࡼࡿࣔࢹࣝᚤ⢊య࠿ࡽᡂࡿ㐀⢏యࢆᐇ㦂ⓗ࡟〇㐀ࡋ㸪ྠ᫬࡟㐀⢏ᶵෆࡢ㐀 ⢏య㐠ືࡢࢩ࣑࣮ࣗࣞࢩࣙࣥࢆ⾜࠸㸪୧⪅ࡢ᝟ሗ࠿ࡽ─ᙧ㐀⢏ᶵ࡟ࡼࡗ࡚ᡤᮃ࡜ࡍࡿ㐀⢏ࢧ࢖ࢬࢆᚓ ࡿࡓࡵࡢ᧯స᮲௳ࡢタᐃ࠶ࡿ࠸ࡣ⿦⨨タィ࡟ࡘ࠸࡚ࡢ᝟ሗࢆᥦ♧ࡋࡓ㸬 จ㞟⢏Ꮚࡢศᩓ㏿ᗘࡢண ࣅ࣮ࢬ࣑ࣝࡣ㸪㢦ᩱࡢศᩓᶵ࡜ࡋ࡚ከ⏝ࡉࢀ࡚࠸ࡿࡀ㸪ศᩓ᧯సࡣ⤒㦂ⓗ࡛࠶ࡾ㸪ᬑ㐢ⓗ࡞᮲௳タ ᐃἲࡀᏑᅾࡋ࡞࠸㸬ࡑࡇ࡛ᮏ◊✲࡛ࡣ㸪ࣅ࣮ࢬ࣑࡛ࣝࡢศᩓ࡟࠾ࡅࡿᬑ㐢ⓗ᮲௳タᐃἲࡢ㛤Ⓨࢆ┠ⓗ ࡜ࡋ࡚㸪㞳ᩓせ⣲ἲ࡟ࡼࡿࣅ࣮ࢬ㐠ືࡢࢩ࣑࣮ࣗࣞࢩࣙࣥࢆ⾜࠸㸪ࡑࡢ㐠ືࢆゎᯒࡋࡓ㸬୍᪉࡛ࣔࢹ ࣝ㢦ᩱヨᩱ࡜ࡋ࡚࣮࢝࣎ࣥࣈࣛࢵࢡ⢊ᮎࢆ㑅ᢥࡋ㸪ࣅ࣮ࢬ࣑ࣝ࡟ࡼࡗ࡚จ㞟⢏Ꮚศᩓᐇ㦂ࢆ⾜࠸㸪ࡇ ࡢ᝟ሗ࡜ࢩ࣑࣮ࣗࣞࢩࣙࣥࡼࡾᚓࡽࢀࡿࣅ࣮ࢬ㐠ືࡢ᝟ሗࢆ⼥ྜࡋ࡚㸪ศᩓ㏿ᗘ࡟ᙳ㡪ࡍࡿ᧯స᮲௳ ࢆ᥈⣴ࡋ࡚࠸ࡿ㸬㌿ື⿦⨨ෆ࡟࠾ࡅࡿ␗ᚄ⢏Ꮚ⩌ࡢ೫ᯒ⌧㇟ゎᯒ ⢏Ꮚᚄศᕸࢆࡶࡘ⢏Ꮚ⩌ࢆ㌿ື⿦⨨࡛㐠ືࡉࡏࡿ࡜㸪᧯స᮲௳࡟ࡼࡗ࡚ࡣ೫ᯒࡀ㉳ࡇࡿࡇ࡜ࡀ▱ࡽ ࢀ࡚࠸ࡿ㸬ࡇࡢ೫ᯒࡣ㸪⢊యࡢΰྜ㸪⢊○㸪᤼ฟ➼ࡢ᧯స࡛㞀ᐖ࡟࡞ࡿሙྜࡀከࡃ㸪೫ᯒᶵᵓᢕᥱࡀ 㔜せ࡛࠶ࡿ㸬ࡋ࠿ࡋ࡞ࡀࡽ㸪೫ᯒⓎ⏕せᅉࡀ」㞧࡛࠶ࡾ㸪ᮍゎỴࡢࡲࡲ࡟࠶ࡿ㸬ᮏ◊✲࡛ࡣ㸪ࡇࢀࢆ ᡴ◚ࡋ㸪೫ᯒࡀ㉳ࡇࡿᬑ㐢ⓗ᮲௳ࡢᢕᥱࢆ┠ᣦࡋ㸪㞳ᩓせ⣲ἲ࡟ࡼࡿ␗ᚄ⢏Ꮚᚄࢆᣢࡘ⢊య࡟ᑐࡍࡿD EMࢩ࣑࣮ࣗࣞࢩࣙࣥࢆ⾜࠸㸪᭷┈࡞᝟ሗⓎಙࢆ⾜ࡗ࡚࠸ࡿ㸬. 14.

(32) 15. 研究活動報告. 㸱㸬᪂つ໬ྜ≀ࡢタィ㺃᥈⣴㸪༢⤖ᬗ໬࡜≉ᛶホ౯ ᰾་Ꮫ㸪ࢭ࢟ࣗࣜࢸ࢕ࢳ࢙ࢵࢡ㸪᰾⼥ྜ㸪㈨※᥈ᰝ㸪⣲⢏Ꮚ࣭Ᏹᐂ≀⌮࡞࡝㸪ᗈ⠊࡞ศ㔝࡛⏝࠸ࡽࢀ ࡿࢩࣥࢳ࣮ࣞࢱࡢ㛤Ⓨࢆ୰ᚰࢸ࣮࣐࡜ࡋ࡚㸪ᅛయ໬ᏛࡢほⅬ࠿ࡽ㸪᪂つ໬ྜ≀ࡢタィ㺃᥈⣴㸪༢⤖ᬗ໬㸪 ࠾ࡼࡧᚓࡽࢀࡓ≀㉁ࡢ≉ᛶホ౯ࢆ⾜࠸㸪ࡑࡢ≉ᛶࢆά࠿ࡍࢹࣂ࢖ࢫタィࡲ࡛⾜࠺ᙧ୍࡛㈏ࡋࡓ◊✲άື ࢆᒎ㛤ࡋ࡚࠸ࡿ㸬ᅜෆඹྠ◊✲࡟ຍ࠼㸪ࢳ࢙ࢥ㸪㟢㸪௖㸪ఀ㸪࢜ࣛࣥࢲ㸪⡿ᅜ➼࡜ࡢᅜ㝿ඹྠ◊✲ࡶ᥎ 㐍ࡋ࡚࠸ࡿ㸬 05,3(7⏝3U㸸/X$*㸩$3'࢔࣮ࣞᨺᑕ⥺᳨ฟჾࢩࢫࢸ࣒ࡢ㛤Ⓨ 㸦1('2 ᖹᡂᖺ᭶㹼ᖹᡂᖺ᭶㸪3/ྜྷᕝ㸧 ᮏ◊✲஦ᴗࡣ㸪ᡃࠎࡀ㛤ⓎࡋࡓPr:LuAGࢩࣥࢳ࣮ࣞࢱ࡜ᮾᕤ ኱∦ᒸࢢ࣮ࣝࣉ㸦⌧࣭᪩✄⏣኱㸧ࡀ㛤ⓎࡋࡓAPD࢔࣮ࣞᢏ⾡࡜ ᮾ኱㧗ᶫ◊ࡢ᭷ࡍࡿASICᢏ⾡ࢆ኱ᏛⓎࢩ࣮ࢬ࡜ࡋ࡚⏝࠸㸪ྂἙ ᶵᲔ㔠ᒓओࢆᐇ⏝໬஦ᴗ⪅࡜ࡋ࡚௻⏬ࡋࡓ㸬Pr:LuAGࡣ㸪PET ⏝࡜ࡋ࡚⪃࠼ࡽࢀ࡚࠸ࡿ㧗࠸Zࢆᣢࡘࢩࣥࢳ࣮ࣞࢱࡢ୰࡛᭱ࡶ ㏿࠸ᛂ⟅㏿ᗘ࡜᭱㧗࢚ࢿࣝࢠ࣮ศゎ⬟ࢆ᭷ࡍࡿࡓࡵ㸪ࡇࢀࢆά ࠿ࡋ࡚☢ሙ୙ឤࡢMRI-PET⏝LuAG㸩APD࢔࣮ࣞ㸩ASICࢩࢫ ࢸ࣒ࡢ◊✲㛤Ⓨࢆ⾜࠺ࡶࡢ࡛࠶ࡿ㸬MRI-PETࡢᐇ⌧࡟ࡼࡾ㸪⿕ ⇿㔞పῶ࣭ゎീᗘྥୖ࡟ຍ࠼㸪⾑ὶ➼ࡢᶵ⬟᝟ሗࡶᚓࡽࢀࡿࡇ ࡜ࡀᮇᚅ࡛ࡁࡿࡓࡵ㸪MRI-PET᳨ฟჾࢩࢫࢸ࣒ࢆୡ⏺࡟ඛ㥑ࡅ ࡚ᐇ⌧ࡋ㸪ୡ⏺ࢩ࢙࢔ࡢ☜ಖࢆ┠ᣦࡋ࡚࠸ࡿ㸬. Pr:LuAG࢔ࣞ࢖ (ྜྷᕝG) APD࢔ࣞ࢖ (ᮾᕤ኱࣭∦ᒸG) ASIC (ᮾ኱࣭㧗ᶫ◊) ᅗ1㸬APD࢔࣮ࣞᨺᑕ⥺᳨ฟჾࣘࢽࢵࢺ. 㧗㏿ࢭࣝ࢖࣓࣮ࢪࣥࢢࢆྍ⬟࡟ࡍࡿḟୡ௦;⥺&7⏝ࣁࣟࢤࣥ໬≀ࢩࣥࢳ࣮ࣞࢱࡢ㛤Ⓨ 㸦ཌ⏕┬⛉◊㈝ ᖹᡂᖺ᭶㹼ᖹᡂᖺ᭶㸪3/ྜྷᕝ㸧 ᅗ㸰㸬2࢖ࣥࢳ ࣇࢵ໬≀㸪ሷ໬≀㸪⮯໬≀㸪ࣚ࢘໬≀࡜࠸ࡗࡓࣁࣟࢤࣥ໬ Nd:LaF3 ≀࡟ᕼᅵ㢮⺯ගඖ⣲ࢆຍ࠼㸪┿✵⣸እ㡿ᇦ࡛Ⓨගࡍࡿࣁࣟࢤ ࣂࣝࢡ༢⤖ᬗ ࣥ໬≀ࢩࣥࢳ࣮ࣞࢱࢆ㛤Ⓨࡋ࡚࠸ࡿ㸬ࡇࢀࡣ㸪┿✵⣸እᇦ࡟ ឤᗘࢆᣢࡘ᳨ฟჾ࡛࠶ࡿ࢞ࢫ࢝࢘ࣥࢱ࣮(GC)࡜⤌ྜࡏࡿࡇ ࡜࡛㸪Ᏻ౯࡛㧗ゎീᗘࡢḟୡ௦X⥺CTࢭࣥࢧ࣮㒊࡬ᛂ⏝ࡀ ᮇᚅࡉࢀࡿ㸬 2࢖ࣥࢳNd:LaF3㸪LuLiF4➼ࡢࣂࣝࢡ༢⤖ᬗ 㸦ᅗ1ཧ↷㸧స〇࡟ᡂຌࡋ㸪࣐࢖ࢡࣟࣆࢡࢭࣝ࢞ࢫ࢝࢘ࣥࢱ ࣮(ȣ-PIC)ࡢᢏ⾡ࢆ᭷ࡍࡿி኱㇂᳃◊࠾ࡼࡧᮾ኱㛵㇂G࡜ࡢ ඹྠ◊✲࡟ࡼࡾ㸪᧜ീ࡟ࡶᡂຌࡋࡓ (ᅗ2)㸬 ᅗ3㸬 Nd:LaF3༢⤖ᬗ࡜ȣ-PICࢆ⏝࠸ࡓ ᧜ീ⤖ᯝ ḟୡ௦ࢭ࢟ࣗࣜࢸ࢕⏝୰ᛶᏊࣛࢪ࢜ࢢࣛࣇ࢕⿦⨨ࡢ㛤Ⓨ 㸦㔜Ⅼᆅᇦ◊✲㛤Ⓨ᥎㐍ࣉࣟࢢ࣒ࣛ ◊✲㛤Ⓨ㈨※ά⏝ᆺ

(33) ᖹᡂᖺ᭶㹼ᖹᡂᖺ᭶㸪3/ྜྷᕝ㸧 ᮏ஦ᴗࡣ㸪ᡃࠎࡀओࢺࢡ࣐ࣖ࡜ඹྠ࡛㛤Ⓨࡋࡓ୰ᛶᏊ᳨ฟ⏝ࢩࣥࢳࣞ ࣮ࢱ࡛࠶ࡿ㻸㼕㻯㼍㻭㼘㻲㻢ࢆ㸪᪥ᮏ⤖ᬗගᏛओࡢ㻼㻰࢔ࣞ࢖ㄞࡳฟࡋᢏ⾡࡜⤌ࡳ ྜࢃࡏ㸪୰ᛶᏊࣛࢪ࢜ࢢࣛࣇ࢕⿦⨨࡟࠾ࡅࡿ㸪᳨ฟჾࢩࢫࢸ࣒ࡢ㛤Ⓨࢆ ⾜࠺ࡶࡢ࡛࠶ࡿࠋ⌧≧࡟࠾࠸࡚⣧⢋࡟୰ᛶᏊ࠿ࡽࡢࢥࣥࢺࣛࢫࢺࢆ⏝࠸ ࡓ㻯㼀⿦⨨ࡣ࡞࠸ࡢ࡛㸪ᮏ◊✲࡛ࡣࡑࡢᢏ⾡ⓗ✺◚ཱྀࢆᣅࡃ࡭ࡃ㸪㧗ຠ ⋡࡞୰ᛶᏊ᳨ฟჾࢆ㛤Ⓨࢆ⾜࠺ࠋࡇࢀࡀᐇ⌧ࡍࡿࡇ࡜࡟ࡼࡗ࡚ࢭ࢟ࣗࣜ ࢸ࢕ศ㔝࡟࠾ࡅࡿ⏬ᮇⓗ࡞᳨ᰝ⿦⨨ࡢㄌ⏕ࡀᮇᚅ࡛ࡁࡿࠋ㻌 ᅗ4㸬 ᮏ஦ᴗ࡛㛤Ⓨࡋࡓ ┿✵⣸እⓎගࢆ฼⏝ࡋࡓ᪂つ㧗㏿ᛂ⟅ࢩࣥࢳ࣮ࣞࢱ⤖ᬗࡢ㛤Ⓨ LiCAF༢⤖ᬗ ࠾ࡼࡧࢹࣂ࢖ࢫᢏ⾡ࡢ㛤Ⓨ 㸦⛉◊㈝ⱝᡭ$ ᖹᡂᖺ᭶㹼ᖹᡂᖺ᭶㸪3/ྜྷᕝ㸧㝧㟁Ꮚ᩿ᒙ᧜ᙳ⿦⨨㸦PET㸧➼ࡢࣇ࢛ࢺࣥ࢝࢘ࣥࢸ࢕ࣥࢢࡀᚲせ࡞་⒪⏬ീ⿦⨨࡟ᦚ㍕ࡉࢀ࡚࠸ࡿ ᭱㏿ᛂ⟅ࡢࢩࣥࢳ࣮ࣞࢱࡣCe:Lu2SiO5 (LSO)㸪Ce:Gd2SiO5 (GSO)࡜࠸ࡗࡓCe⣔࡛࠶ࡾ㸪ᨺᑕ⥺᳨ฟ ჾࡢᛂ⟅㏿ᗘࡣ50㹼100ࢼࣀ⛊(ns)⛬ᗘ࡜࡞ࡿࡀ㸪ḟୡ௦ࢩࣥࢳ࣮ࣞࢱ࠾ࡼࡧᨺᑕ⥺᳨ฟჾ࡟ࡣᩘns ࡢ㧗㏿᫬㛫ᛂ⟅ࡢ㛤Ⓨࡀᛴົ࡜ࡉࢀ࡚࠸ࡿ㸬⺯ගᑑ࿨ࡣ㸪Ἴ㛗ࡢ3஌࡟ẚ౛ࡋ㸪▷Ἴ㛗Ⓨග࡯࡝᪩࠸ᛂ.