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福岡大学審査学位論文

氏 名 くしだひろたか 串田浩孝 学位の種類博士 ( 薬学 ) 報告番号乙第 1590 号 学位授与の日付 平成 27 年 9 月 29 日 学位授与の要件学位規則第 4 条第 2 項該当 ( 論文博士 ) 学位論文題目 釣藤鈎アルカロイドの薬物動態に関する研究 論文審査委員 ( 主査 ) 福岡大学

氏 名 くしだひろたか 串田浩孝 学位の種類博士 ( 薬学 ) 報告番号乙第 1590 号 学位授与の日付 平成 27 年 9 月 29 日 学位授与の要件学位規則第 4 条第 2 項該当 ( 論文博士 ) 学位論文題目 釣藤鈎アルカロイドの薬物動態に関する研究 論文審査委員 ( 主査 ) 福岡大学

... しかしながら、生薬や漢方製剤の薬物相互作用や副作用に関わるそれらの成分の吸収、分 布、代謝及び排泄といった、いわゆる薬物動態学的研究はほとんど行われていない。それは、 漢方薬が複数生薬からなる多成分系合剤であるためである。漢方薬の薬物動態学的研究を行 うためには、その中から生体作用成分を先ず見つけ、それらを検出する分析法を確立する必 要がある。そこで、本研究では、釣藤鈎アルカロイドの高速液体クロマトグラフィー/直列 ...

15

島根大学審査学位論文(k600)

島根大学審査学位論文(k600)

... This study found no evidence for seasonal variations in hospital admissions due to IC, though IC may recur more frequently in the same season as the initial event.. Declaration of confli[r] ...

12

島根大学審査学位論文(k688)

島根大学審査学位論文(k688)

... We evaluated the expression of MMR proteins, tumor-infiltrating lymphocytes (CD8+), and immune checkpoint molecules (PD-L1/PD-1) by immunohistochemistry in 136 ovarian cancer patients (7[r] ...

12

島根大学審査学位論文(k678)

島根大学審査学位論文(k678)

... Together with pGL4.74 Renilla luciferase expression vector, each pGL4.18 BART promoter vector was transfected into EBV-negative and positive AGS, MKN28, SNU719, and HONE1 cells.. The BAR[r] ...

6

島根大学審査学位論文(k679)

島根大学審査学位論文(k679)

... We examined the effects of intrathecal administration of TRPV1 antagonist on morphine-induced itch, body temperature, and antinociception for mice.. Methods: Each C57/BL6j mouse was in[r] ...

22

島根大学審査学位論文(k669)

島根大学審査学位論文(k669)

... mentioned in section 3, the color moirés are the results of the pixel pattern blocking by the VZFO line pattern. The blocking will be more as the line thickness increases. In t[r] ...

115

島根大学審査学位論文(k677)

島根大学審査学位論文(k677)

... Supplementary Materials: The following are available online at http://www.mdpi.com/2072-6643/11/4/888/s1 , In supplementary file 1 (Table S1: Primer sequence for real time PCR), In suppl[r] ...

17

島根大学審査学位論文(k676)

島根大学審査学位論文(k676)

... The numbers of elapsed days from onset to the first consultation, first MRI, and each stage of the medical consultation process to reach a definitive diagnosis were analyzed between t[r] ...

11

島根大学審査学位論文(k671)

島根大学審査学位論文(k671)

... Our observation that the coverage of brain blood vessels by AQP4-immunoreactive astrocytic endfeet was significantly diminished in Gunn rats presenting depressive-like behavior is consis[r] ...

9

島根大学審査学位論文(k683)

島根大学審査学位論文(k683)

... prolactin expression in the anterior pituitary prolactin-producing cells under the influence 23.. of E2, which may regulate Kiss1R expression and function..[r] ...

36

島根大学審査学位論文(k626)

島根大学審査学位論文(k626)

... In the pres- ent study, patients who were receiving antithrombotic treat- ment (warfarin 47, aspirin 98, others 50) comprised 4.6 % of the total, with no differences in regard to type of[r] ...

7

島根大学審査学位論文(k603)

島根大学審査学位論文(k603)

... AGE3-BSA Induced Expression of NAD(P)H Oxidase Components and ROS Generation in VSMCs To evaluate further about the roles of NAD(P)H oxidase in AGE-induced apoptosis of VSMC, we checked [r] ...

14

島根大学審査学位論文(k682)

島根大学審査学位論文(k682)

... A phase II study of palonosetron, aprepitant, dexamethasone, and olanzapine for the prevention of cisplatin-based chemotherapy-induced nausea and vomiting.. in patients with thoracic m[r] ...

23

島根大学審査学位論文(o339)

島根大学審査学位論文(o339)

... Given that decreasing the length of a peptide tag has the disadvantage of increasing its reactivity with endogenous proteins containing the same sequence, we were surprised to observe [r] ...

20

島根大学審査学位論文(k593)

島根大学審査学位論文(k593)

... The present study showed that CD11b expression was significantly increased in the hippocampal DG, CA1, and CA3 areas in Gunn rats compared to Wistar rats.. The finding that microglia in [r] ...

13

島根大学審査学位論文(k681)

島根大学審査学位論文(k681)

... EGFR: Epidermal growth factor receptor; FGFR: Fibroblast growth factor receptor; NSCLC: Non-small cell lung cancer; PFS: Progression-free survival; PTK2: Protein tyrosine kinase 2; RT-qP[r] ...

14

島根大学審査学位論文(k591)

島根大学審査学位論文(k591)

... Oxidative stress in the rostral ventrolateral medulla (RVLM), a sympathetic center in the brainstem, was implicated in the regulation of sympathetic activity in various hypertensive mod[r] ...

8

島根大学審査学位論文(k590)

島根大学審査学位論文(k590)

... In the present study, in addition to the single-layered structure of the epithelium with apical mitotic fig- ures, a general cyclic change in the EdU (+) nuclei distribution pattern w[r] ...

8

島根大学審査学位論文(k587)

島根大学審査学位論文(k587)

... We have shown that bladder neck movement analyzed by magnetic resonance imaging (MRI) was useful for understanding the beneficial effects of pelvic floor muscle training (PFM-tra[r] ...

8

島根大学審査学位論文(o337)

島根大学審査学位論文(o337)

... 水環境に関する研究リスト 発表論文 1) Takatoshi FUJII, Yoshihiro AKIYAMA, Yoichi NAKANO, Kaoru AOKI, Yusuke DATE, Ryoma MIYAKAWA, Hitomi YANO, Eiichi HINO, Yuzo FUJII, Tetsuji OKUDA, Wataru NISHIJIMA, Relationship between Sediment ...

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