研究業績・活動報告2018

東北大学多元物質科学研究所. 研究業績・活動報告. 2018年 (平成30年)12月. 多元物質科学研究所研究業績・活動報告. 目次. 研究活動報告 ········································································· 1 有機・生命科学研究部門 ··································································································· 1 無機材料研究部門 ············································································································ 15 プロセスシステム工学研究部門 ·························································································· 26 計測研究部門 ·················································································································· 38 非鉄金属製錬環境科学研究部門 ·························································································· 57 金属資源プロセス研究センター ·························································································· 59 先端計測開発センター ······································································································ 77 高分子・ハイブリッド材料研究センター ·············································································· 85 新機能無機物質探索研究センター ······················································································· 99. 研究会報告 ············································································ 109. 学会発表講演目録 ··································································· 155 有機・生命科学研究部門 ··································································································· 155 無機材料研究部門 ············································································································ 157 プロセスシステム工学研究部門 ·························································································· 159 計測研究部門 ·················································································································· 161 非鉄金属製錬環境科学研究部門 ·························································································· 164 金属資源プロセス研究センター ·························································································· 164 先端計測開発センター ······································································································ 168 高分子・ハイブリッド材料研究センター ·············································································· 169 新機能無機物質探索研究センター ······················································································· 171. 研究業績目録 ········································································· 174 有機・生命科学研究部門 ··································································································· 174 無機材料研究部門 ············································································································ 178 プロセスシステム工学研究部門 ·························································································· 180 計測研究部門 ·················································································································· 183 非鉄金属製錬環境科学研究部門 ·························································································· 189 金属資源プロセス研究センター ·························································································· 189 先端計測開発センター ······································································································ 194 高分子・ハイブリッド材料研究センター ·············································································· 197 新機能無機物質探索研究センター ······················································································· 202. 業績目録著者索引 ··································································· 206. 1 研究活動報告. 2018. 1 2018. 12. (2018 6 ) ( 2018 12 ). ( 2018 7 ) (2018 11 ). ( 2018 3 ) ( 2018 3 ). ( 2018 9 ). (2018 4 ). (2018 7 ). 2018. RNA. ( ). RNA. 1,3- G-cla. mp G-clamp-dimer (1). RNA. pre-. miRNA-17 shRNA(-XUY-). RNA ( 3) G-cl. amp domer (1) shRNA(-GUG-) RNA. shRNA(-CUA-). RNA G-cla. G N. N. N. O. N N. O. N. N N. O. O. R. H. H. H. H. NH2 H. R. G N. N. N. O. N N. O. N. N N. O. O. H. H. H. H. NH2 H. 1,3-. G-clamp. OO. HH22 NN. OO. OO. NN. NN. HNHN. OO. HH NN NN. HH NN. OO. OO. NHNH. NN. NN. OO. OO. NHNH22. G-clamp dimer (1. 研究活動報告 2. mp-dimer (1). pre-miRNA-17. G-clam. p-dimer (1). 2.. ( ) . 1). (2: Ar = Ph or An) ( ) 2 ODN1 (X = 2). 2- ODN2 (Y = 2-AP). ODN2 ODN1 (X = 1b). 1) K. Onizuka, A. Usami, Y. Yamaoki, T. Kobayashi, M.E. Hazemi, T. Chikuni, N. Sato, K. Sasaki, M.. Katahira, F. Nagatsugi, Nucleic Acids Res. 2018, 46, 1059-1068.. Flipped-out. base. O. O. O N O. DNA. Ar. DNA. Ar = X =. ODN1: 5’-d(GCGCXGCCAG)-3’ ODN2: 3’-d(CGCGYCGGTC)-5’. a Phenyl(Ph). b: Antracenyl(An). 2. Y =. 2-amino purine. (2-AP). N. N. N. N. NH 2. DNA. ODN3: 5’-d(GCGCAnGCCAG)-3’. ODN4: 3’-d(CGCAnACGGTC)-5’. Ar =. UV, O2. 10 min. rt. AU 5’UAGUG A. ||||| U 3’AUCAC X. YU OO. HH22 NN. OO. OO. NN. NN. HNHN. OO. HH NN NN. HH NN. OO. OO. NHNH. NN. NN. OO. OO. NHNH22. Fluorescence titration. A solution of 10 nM ligand and 0 - 160 nM. shRNA(-XUY-) in the buffer containing 10 mM HEPES-NaOH. and 100 mM NaCl at pH 7.4 was excited at 360 nm at 20 o. C.. 3 研究活動報告. 2018 1 2018 12. 2018. pH 5.8 6.2. pH7.2. anti syn RNA on-off. ( -PRNA, -PRNA) RNase H RNA. PRNA DNA. (PNA) (PRPD) RNA. PRNA PRNA. pH pH pH. on-off -PRNA. (PBA) -PRNA-PBA (Fig.1). PRNA RNA on-off pH (pKs) PBA. -PRNA-PBA pH. RNA RNase H RNA. PRPD -PRNA -PRNA-PBA pH (PRBPD). DNA CPG DNA DNA 5’. PNA-PRNA Fmoc PBA. - PBA. PRBPD. PRBPD DNA RNA. (Tm). PRBPD RNA. DNA 20. 研究活動報告 4. RNA. RNase H RNA RNA. PRBPD RNA PRPD RNA RNase H. RNA. RNA. (PRNA). CD. CD. [6]. CD [9]. CD Fig.2. CD [9]. 800 nm Tn T1. P -[9] (M)-[9]. DFT. 3D. 2-. 98%. - (HSA). HSA. HSA (Fig.3). HAS UV/Vis CD. HSA -H, -CHO, -COOH. HSA. Transient CD (upper) and absorption (lower) spectra of [9]heliene in toluene at room temperature obtained at 1-10 s after ns-laser irradiation.. COOH. COOH. HOOC. COOH. OHC. 4-Stilbenecarboxylic acid. 4, 4'-Stilbenedicarboxylic acid. 4-Formyl-4'-stilbenecarboxylic acid. 5 研究活動報告. 2018 4 12. –. –. 研究活動報告 6. “Emergence of metallic monoclinic states of VO2 films induced by K depositio”; D. Shiga, M. Minohara, M.. Kitamura, R. Yukawa, K. Horiba, and H. Kumigashira, arXiv:1811.10070.. º. º. º. “Growth of antiperovskite oxide Ca3SnO films by pulsed laser deposition”; M. Minohara, R. Yukawa, M.. Kitamura, R. Kumai, Y. Murakami, and H. Kumigashira, J. Cryst. Growth 500, 33 (2018).. Ca3SnO RHEED. XRD (a) 2 -. (b) (202). 7 研究活動報告. 2018 1~2018 12. D3 (D2) Bui Ba Han D2 D1. D1 (M2) Elza F. Sofia M2 M1. M1 M1. 1. ERp44. PDI ERp44. KDEL ERp44. pH (Vavassori, Masui. et al., Mol Cell 2013, Watanabe et al., Proc. Natl. Acad. Sci. USA., 2017) ERp44. Watanabe, Amagai, et al., Nat.. Comm., in press ERp44. ZnT ZIP. ERp44. ERp44. ERp44. 2. KDEL 1,2,3. KDEL (KDELR) G. C Lys-Asp-Glu-Leu (KDEL). KDELR. KDELR1 KDELR2 KDELR3. BioID BioID-KDELR KDELR. KDELR. 研究活動報告 8. KDELR1. 2 KDELR3. 3. ATP. SERCA2b SPCA1a ATP. SERCA2b. TM11 SERCA2b. (Inoue et al., to be published) Cryo-EM. SPCA1a SPCA1a. SPCA1a SERCA2b 6 1. ATPase SPCA1a X Cryo-EM. 4. PDI PDIp. 20 PDI. PDIp. PDI PDIp. PDIp. PDIp. PDIp PDIp. PDIp. PDIp PDIp. 4 PDI. PDIp. PDI PDIp. (Fujimoto et al.,J. Biol. Chem. 2018) PDI. Fujimoto et al., Protein. Sci. 2019. 5. LDL. LDL (LDLR). LDLR R 3 EGF. LDLR R 3 EGF. LDLR. 1) LDLR. 2) 2 LDLR. N R 3). 2 R1 4) LDLR. C LDLR. C LDLR. R R1. 5) R1. 9 研究活動報告. 6) R1 R EGF1, 2 a). b) R1. (Kadokura et al., to be published). 6.. KDEL. HeLa. DTT. DTT. 10 40 Calreticulin. CD4 HeLa CD4. CADA. 7. GPx7/8 PDI. GPx7 GPx8 PDI. peroxidative cysteine (Cp) resolving cysteine Cr Cp. GPx7 GPx8 PDI GPx7. GPx8. GPx7 GPx8 Cp pKa GPx7 Cp GPx8 Cp pKa. GPx7 GPx7 Cp pKa. GPx7 PDI ERp46 GPx8 ERp72. GPx7 GPx8 PDI. GPx7 GPx8. 8. PDI. ( ) 30%. PDI. PDI ERp46. PDI. ERp46. PDI dimer. 研究活動報告 10. 9. ERdj5 BiP. ERdj5 EDEM1 BiP. PDI ERdj5 BiP. IgM joint chain J-oligomer BiP. ERdj5 J-oligomer ERdj5. BiP BiP Sil1. 10. P5. PDI P5. P5 3. P5 X. P5. P5 PDI. P5. 11.. PDI. (GdnSH) GdnSH. (S-). GdnSH 2. (Okada, Matsusaki et al. Chem.Comm. in press). 12. PDI. PDI. PDI. PDI. 11 研究活動報告. 2018 1 2018 12. :. :. :. : Priya Ranjan Sahoo (2018.7~), Himadri Sekhar Sarkar (2018.12~). :. : (~2018.6), (2018.7~). : , , , , , ,. , , , , Ira Novianti. : Kashfia Ahamed, Rong Liu, Boyuan Mao. 2018. 1 Zn2+. Zn2+ 2. 3. DHFR. DHFR NADPH. MTX MTX MTX. azoMTX 1. azoMTX eDHFR 7 nM 0.2 nM. 35 azoMTX eDHFR. 研究活動報告 12. Zn2+. Zn2+. Zn2+. Zn2+. Zn2+. Zn2+. Zn2+. Zn2+. pH. pH Zn2+ ZnDA-1H. 2 ZnDA-1H 440. nm 506 nm Zn2+ 16. 204 nM. pH pH 5.5–8.0 pH. HEK293T 2c HaloTag. ZnDA-1H ZnDA-1H. Zn2+. Zn2+ 209 nM Zn2+. HO. CO. HO. 3. HO. HO. 3 S-HO S-HO. S- HO. S-HO HO. S-HO. UnaG. S-HO. (a) (b). (c). N O O. N. N. N. HN. O. O O. Cl. cytosol nucleus mitochondria. ER Golgi non-transfection. 30 µm. 13 研究活動報告. 2018.1 2018.12. PD. D3 Dwiky Rendra Graha Subekti D2. M2 M2 M2. Supawich Kamonsprasetsuk M2 M1. M1. Yu Zhang B4, 2018.9 Trishit Banerjee B4. p53 DNA DNA. 2018. HPD 10 5ms. H. Oikawa, T. Takahashi, S. Kamonprasertuk, S. Takahashi, Phys. Chem. Chem. Phys., 20, 3277–3285 (2018) .. S. Takahashi, A. Yoshida, H. Oikawa, Biophys. Rev., 10, 363–373 (2018) .. 研究活動報告 14. LAF-1 LAF-1. F1ATPase. DNA DNA. DNA DNA DNA. Nhp6A, HU Fis DNA. K. Kamagata, E. Mano, K. Ouchi, S. Kanbayashi, R. C. Johnson, J. Mol. Biol., 430, 655–. 667 (2018). DNA. 30ms. p53 DNA. DNA. DNA DNA Nhp6A, HU Fis. DNA. DNA DNA. DNA DNA. M13 g8p GFP. 10. 15 研究活動報告. 2018 1 2018 12. :. : ,. :. : , , ,. , , ,. , ,. 2018. GP. Al-Cu, Al-Ag, Mg-Gd, Mg-Nd, Mg-Zn GP. Al, Mg GP. GP Mg-Ca-Al, Mg-. Ca-Zn GP. i s. Fe-Ti-N Fe-V-N. 4. 研究活動報告 16. 100 200 °C. (Fe2C). BCT. Fe2C. 2018 BCC. BCT. MI2I 2018. B P. McLean Langmuir. Hillert. 3. 17 研究活動報告. 2018.1 2018.12 . . . Thomas Gaudisson. , , . 3 . Thomas Gaudisson 4 10. 3 9 2018. X. K. X XANES. 2 3 6. SIMS SIMS TOF-SIMS. TOF-SIMS. IoT. 研究活動報告 18. <100>. Fe-Co. Fe-Co. <100> Fe-Co. <100>. fcc (bcc) <100>. bcc Fe-Co. <100>. bcc Fe-Co. 19 研究活動報告. 2018. 1 2018.12. :. : ,. JSPS Kittiwit Matan 2018.6 12. JSPS Johannes Reim. : , Kim Sandvik, Aji Seno,. Pharit Piyawongwattahana,. :. 2018 4 4 1. Kittiwit Matan JSPS 2018. PrTr2Al20 (Tr = Ti, V) [1]. Na3Mn(CO3)2Cl [2] LiZn2Mo3O8. [3] [4]. PrT2Al20. PrT2Al20 (T = Ti, V). PrTr2Al20 (Tr = Ti, V) Fd-3m Pr3+ 4f. Pr3+ Td 1, 3, 4, 5 4. 3. 3. Tr = V PrV2Al20. PrV2Al20 4f. Pr Tr = Ti V. PrTi2Al20. PF BL-8A Al Ti. V. Al Al. Pr V Pr. Tr = V 5. 研究活動報告 20. Tr = Ti, V. 1: (a, b) PrTr2Al20 (Tr = Ti, V) (c) PrTr2Al20 (d, e) Pr-Al. Tr-Al Al (f-j) Pr-Al(3). Pr-Al(1) Tr-Al(2) Tr-Al(1) Tr. [1]. 2000. 230. 1651. web. [1] Crystal Structure in Quadrupolar Kondo Candidate PrTr2Al20 (Tr = Ti and V), D. Okuyama, M. Tsujimoto, H. Sagayama, Y. Shimura, A. Sakai, A. Magata, S. Nakatsuji, T. J. Sato, J. Phys. Soc. Jpn. 88 015001(1)- 015001(2) (2019). [2] Degenerate ground state in the classical pyrochlore antiferromagnet Na3Mn(CO3)(2)Cl, Nawa, Kazuhiro, Okuyama, Daisuke, Avdeev, Maxim, Hiroyuki Nojiri, Masahiro Yoshida, Daichi Ueta, Hideki Yoshizawa, and Taku J. Sato, Phys. Rev. B 98 144426(1)-144426(8) (2018). [3] Controlling the stoichiometry of the triangular lattice antiferromagnet Li1-xZn2-yMo3O8, Kim E. Sandvik, Daisuke Okuyama, Kazuhiro Nawa, Maxim Avdeev, Taku J. Sato, J. Solid State Chem. 271 216- 221 Jan 2019 [Refereed] [4] http://www2.tagen.tohoku.ac.jp/lab/sato_tj/magnetic-representations-and-magnetic-space-groups/. 21 研究活動報告. 研究活動報告 22. f. H. H f. f. H. t. t. h. 23 研究活動報告. 2018.1 2018.12. 2018. GaN. NH4Cl AlN. NH4Cl AlN GaN. GaN. GaN NH4Cl. AlN NH4Cl. +. + PVT. 13 (BN). (AlN). 13. 13 AlN. BN AlN. Al2O3. AlN. 研究活動報告 24. 25 研究活動報告. 研究活動報告 26. 2018 1 2018 12. ,. , , , ,. Varu Singh, ,. Zamir Hossain Muhammad, Litwinowicz Andrzej-Alexander,. Xiao Dong Hao, , , ,. , , , , ,. , , ,. ,. 2018. 1.. CeO2 (C18-CeO2). D. 1. -. 2.. Ni@BaTiO3 Ni BaTiO3. 300 °C. 200 °C. 2 Ni@BaTiO3 STEM-EDX. 1 D. C18-CeO2. × : 0.01 wt%. : 0.01 wt%. : 0.1 wt%. : 1 wt%. × : 0.01 wt%. : 0.01 wt%. 1 wt%: 0.1 wt. wt%: 1 wt%. 27 研究活動報告. BaTiO3 Ni. 3.. CeO2 ,. ,. (CH4 + H2O CO +3H2 H,298 = 206 kJ/mol). : 2 CH4 + CeO2 2 CO2 + H2 + CeO2-x ;. : H2O + CeO2-x H2 + CeO2.. CeO2 300 °C. 3. COx H2. 4. Ce. CeO2 {100}. OSC CeO2 OSC Ce3+. STEM-EELS 5-12nm. CeO2 EELS. Ce3+. 4. 4. 研究活動報告 28. 2018. 1 2018. 12. 1010W. 1014W/cm2. TEM 10. 100 nm 3. GC-MS. CnH2n+2; n = 5 ~ 11. n + 1 2n C2nH4n+2. C2nH4n+2 CnH2n+2. 29 研究活動報告. 10%. 1 2. 2 3. 488 nm 1.45. 100 nm. 100 nm. 3. 3. 2. 3 1 2. 3. 1 2 3. 研究活動報告 30. 1 m 2 1.15. 10 m. 3. 3. Vortex Bessel Airy. 1. 2.. 10.1%. 200 keV 35 nm. a 200 keV. Vortex 19%. b. 31 研究活動報告. 2018 1 2018 12. Mahunnop Fakkao(D3) (D1) Hou Xueyan(D1). (M2) (M2), (M2),. (M2) (M1) (M1). (B4) (B4), Reyhan Daffa Athariq(B4). (B3) (B3). Wang Xinxin. 2013 JST ALCA Li. Li ASSLIB. SOFC Li LIB. 2008. NEDO. SOFC 2017. NEDO. JST. 2018. SOFC Li LIB ASSB. Operando. SOFC: / , LIB: ASSB:. SOFC LIB ASSB. X. 研究活動報告 32. X Operando SOFC. SOFC. SOFC. PCFC. PCFC 3 X. 3 X CT X. µm. 10. X. X. X. Li Li. Li X. Li. 33 研究活動報告. NH4MgF3. (NH4)2MgF4 Mg Li. NMR. 研究活動報告 34. (2018 1 2018 12). , (3 ),. , , ,. (M2),. , , (M1). ,. 2018. 1. (Discrete Element Method: DEM). 2018. 2. 35 研究活動報告. 2018 DEM. 3. (. ). 2018. 3.1. (Phase Change Material, PCM). PCM. (16K14543). ( ). /. (. ). 3.2. 10. 2018. 研究活動報告 36. 2018 1 2018 12. ,. D1. M2 , M2 , M2 ,. M1 , M1 , M1. MU Wangzhong (KTH, 2018.10.29~2018 11 16). 37 研究活動報告. ( ). ( 1600~600 ). X. NMR. 0.5-1.5 W/m K. ( 0.5 W/m K) (1.5 W/m K ). CaO-MgO-SiO2-Al2O3 Ca/Mg. /. ( ). 研究活動報告 38. 2018 1 2018 12. ,. Nemer Ahmad (~2018.3). You Daehyun (D2), Aktar Shejuty (D1), (M1). Luo Yu (B4). 2018. (LIED). (RWP). LIED RWP. RWP. LIED. 3 CO2. IAM. ab initio. ab initio. ab initio. 1-1 CO2. (MCF) ab initio. IAM. 39 研究活動報告. free electron laser; FEL FERMI. EUV. FERMI. Eisenbud-Wigner-Smith EWS. Ne EWS. 2 FEL. EWS. single-photon laser-enabled Auger decay;. spLEAD spLEAD. Ne spLEAD. [2.1] D. You et al., in preparation.. X. X. SACLA X. 3.1 20. 100 1. ab initio. [3.1] H. Fukuzawa et al., submitted.. 研究活動報告 40. Rev. Sci. Instrum.. Phys. Rev. Lett.. J. Phys. Conf. Ser.. 41 研究活動報告. Rev. Sci.. Instrum.. J. Phys. B. to be submitted. J. Chem. Phys. to be reported. K. Rev. Sci. Instrum.. submitted. K. K K K. E. 研究活動報告 42. 2018 1 2018 12. SPring-8. Zeiss Xradia 800 Ultra Lau. 500µm. 43 研究活動報告. Talbot(-Lau). SPring-8, BL28B2. CFRP. Talbot(-Lau). visibility. Talbot. J-PARC Gd. RANS. Gd Gd Si 9µm Gd. 64mm. 研究活動報告 44. 2018 1 2018 12. :. :. :. : 2016.3 2016.4. 2016.3 2016.4. 2017.4 2018.4. :. X. ( ). 2018 .. 1. X Tb1-xGdxMn2O5. RMn2O5 (R: ). TbMn2O5 Tb T = 12 K. a. TbMn2O5 Tb Gd 50 %. Tb0.5Gd0.5Mn2O5 T = 12 K. Tb Gd. qM = (1/2,0,1/4) (1/2,0,0). Tb0.5Gd0.5Mn2O5. Figure 1 Tb0.5Gd0.5Mn2O5. T = 12 K. Gd3+. L = 0. Gd3+. Tb0.5Gd0.5Mn2O5. Tb0.5Gd0.5Mn2O5. X. qM = (1/2,0,0). qM = (1/2,0,1/4). Mn. Fig.1: Temperature dependences of electric polarization in Tb0.5Gd0.5Mn2O5 under magnetic field.. 45 研究活動報告. Tb0.5Gd0.5Mn2O5. 2. PbSc1/2Ta1/2O3 X. PbSc1/2Ta1/2O3 ABO3 -. A Pb2+ B Ta5+ Sc3+ 1:1. B Ta5+ Sc3+ 2. Fm-3m ABO3. Pm-3m 2x2x2. 2 B. Ta5+ Sc3+ 1:1. Pm-3m. B. PbSc1/2Ta1/2O3 m. X. F Fobs. Fcalc Fig.2. all-odd. all-even Pm-3m. 3 S 0.089 S < 0.4. 2 B Ta5+ Sc3+. 7:3 3:7. Fig.2: Fobs vs. Fcalc plot on the structure analysis in PbSc1/2Ta1/2O3 at T = 300 K.. 研究活動報告 46. 2018.1 2018.12. :. :. : MOTT Derrick Michael. :. : (2018.5 ). : Grasianto LI Xiaoying. : SANTIVONGSKUL Piangrawee. ESR 2018. 1.. 2018. NaCl. 47 研究活動報告. 2.. 2018. 3.. QELS. QELS 1. QELS. 2018 3. QELS. 10. 研究活動報告 48. 4. EPR. 4.1 EPR. EPR CW Continuous. Wave EPR 1 2 nm EPR 2 8 nm. 2 nm CW. CW. SD(B) SS(B) D(B). F{} 2. ' ' D S S S B S B D B B dB S B D B. 31/D B R 1. D S F S B F S B F D B 2. B R CW-EPR SD(B) SS(B) D(B). 1 D(B) ill-posed. 2 F{D(B)} F{SS(B)} 0 cw. wavelet. wavelet. wavelet (1). 4.2 EPR. Tn - Tn. Ca2+ TnC TnI,TnT. TnT: TnC:Ca2+ TnI. Ca2+ TnC TnI. Ca2+ Gaussian. Ca2+. 2 Ca2+ 2. 4.3 EPR. ESR. 49 研究活動報告. 2018 1 2018 12. (TEM) 2018. 1.. (3D-TEM) (BCP). 3. BCP. BCP. 3 2018. (HPLC) BCP. BCP. Poly(styrene-b-isoprene)(PS-b-PI, Mn:42 k Mw/Mn = 1.09 fPI = 0.34, Polymer Source Inc.). HPLC C18 PS-b-PI PS PI. HPLC BCP. 180 OsO4. (TEM) BCP PI. 1H-NMR. PS-b-PI TEM. 1(a) PS TEM. 1(b) PS PI. TEM 1(c). OsO4. PI PS. PS-b-PI. PS-b-PI PS. 1 Poly(styrene-b-isoprene) TEM (a) , (b) PS , (c) PS PI. .. 研究活動報告 50. fPI 0.38 PI. fPI=0.34 3. 3D-TEM. 2. TEM. 3. 3. 3. TEM. 20 nm 30. IR. - -. 100 nm 300 µm × 100 µm. 30 µm. TEM. JEM-2200FS. CMOS. OneView 2. TEM. 2 3. 3(b) = 0.6. 3(c d). CMOS. 51 研究活動報告. 2018 1 2018 12. , , (~2018.3),. (~2018.3), , , , ,. (~2017.3), , , ,. : 2018.10. 2018. Si(001) MOS. high-k. 1nm. Si Si. O2. SiO2/Si(001). SiO2/Si(001). 1/2. SiO2/Si O2 SiO2/Si(001). O2 2. 2 O2. Si Si. O2. 1 SiO2/Si(001). 1/2. 研究活動報告 52. CVD DLC. DLC CVD. DLC. DLC. CVD. CVD. DLC CH4 CO2. DLC. DLC C-H CO2 2 CO2. C-H XPS CO2 sp3. sp2 CO2 O. DLC H OH H2O DLC C. O C-H. DLC O DLC. h-BN 2. CMTA-. Si 3D. Ni. Ni BN. h-BN. 3. Ni. 2 DLC. CO2. 53 研究活動報告. 2018 1 12. 研究活動報告 54. 55 研究活動報告. K. Kojima, Y. Nagasawa, A. Hirano, M. Ippommatsu, Y.. Honda, H. Amano, I. Akasaki, and S. F. Chichibu, Appl. Phys. Lett.. 114, 011102 (2019). 4 TEM. (a) BF (b) HAADF (c). TEM HAADF (d). QW. slope (~4. flat QWs. inclined QWs. AlGaN:Mg. surface. Al0.75Ga0.25N:Si. flat QWs. ) (c). 50 nm. QW1. QW2. QW3. (d). 10 nm. (a) BF (b) HAADF. A. AlN. AlGaN:Si. [0001]. [1120] [1010] 1 m. B [0001]. 5 (a) SEM (b) CL. (c) (d). 研究活動報告 56. 6. I/I-GaN:Mg PL. 7 I/I. GaN:Mg PL NRC. 57 研究活動報告. 2018.4 2018.12. 2018. 1.. 1.1.. –PROSPECT– 2. 2. 1.2.. NMR. ( ). 1.3.. As Cd Pb. 1.4.. 研究活動報告 58. mass ppb. 1.5.. / /. /. 2.. 2.1.. Cu(II) Co(II). X. 2 2. 2.2.. Cu(II) [CuCl3]. [CuCl4]2 2 [CuCl4]2. Co(II) Fe(III). 59 研究活動報告. 2018 1 2018 12. 研究活動報告 60. AlN AlGaN AlGaN. AlN. AlN GaN. AlN GaN. Al 823-1673 K. AlN Al GaN. Al/GaN 0 1673 K. XRD - AlN SEM. AlN 3 h 1473 K AlN. Ni Mo TiC Mo-Si-B. 1800 1800. Cu Ni-C Ru-C. 10 mol%TiC Mo-Si-B ((90-x) Moss- x T2-10 TiC. (mol%)). T2 70Moss-20T2-10TiC (mol%). 4 T2 Moss-T2. Moss-T2-Mo2C Mo3Si. T2. (PROSPECT). (DWR). DWR. (SC) 2 PROSPECT Ni. DWR SC. Ni 6-105 K. 2. 61 研究活動報告. 2018 1 2018 12. :. :. : (4~) (~8). : ( ; 6). : ( ; 5 ) ( ; 11 ). :. ( ). (~3) (~3) (~3). (4~) (4~) (4~). 3. 2016 10 8. 4. 6 5 11. 3 3. 1 4 3. 2018. Fe. 2CaO SiO2-3CaO P2O5. 研究活動報告 62. CaO MgO . MgO-Al2O3 MgO. MgO-Al2O3 CaO-Al2O3. Ca CaO MgO. Al Al 0.25%. MgO-Al2O3 MgO CaO-Al2O3. Al 0.75% MgO MgO-CaO-Al2O3. Al CaO-Al2O3. P. Mn. P Mn P. Mn P. Mn P. SiO2 1400. Mn P. Fe. Fe Fe2+. CaO-SiO2-FeOx Fe. Ca Si 2CaO SiO2-3CaO P2O5 Fe. pH. 2CaO SiO2-3CaO P2O5 CaCO3. CaCO3 -CaO·SiO2 -CS), -CaO·SiO2 -CS), 3CaO·2SiO2 (C3S2),. 2CaO·MgO·2SiO2 (C2MS2) 3CaO·MgO·2SiO2 (C3MS2) pH. 63 研究活動報告. (2018.1 2018.12). (D3) (D1). (M2) (M2), (M2). (M1), (M1), (M1). (B4) (B3). 2018. SPring-8 XAFS. ADEM. (Advanced Distinct Element Method). ADEM. ADEM. 研究活動報告 64. MPS(Moving Particle Semi-implicit). ADEM SPH(Smoothed Particle Hydrodynamics). (A-STEP). CFD(Computational Fluid Dynamics) DEM. 65 研究活動報告. (2018 1 2018 12. Duhamel, Charles Franck. ,. 2018 4 3 10 Charles. 2011 3 11. 2018. (III) (VI). Spring-8 KEK XAFS. Pa. Pa-231. Pa. Pa(V). Np-237 Pa-233. UO2-ZrO2 UO2. 研究活動報告 66. (FP) (MA). FP. UO2 U3O8. FP XRD. Nb Sb. Mo Te FP TG-DTA. UO2-ZrO2 LiF-KF-NaF. TRU. JAEA. ICP-MS TOF-SIMS. U. UO2. 67 研究活動報告. .. ”Nuclear Fuel Cycle. Training Course”. JAEA. 研究活動報告 68. 2018.1 2018.12. Sven Stauss. Truong Quang Duc. (DC3) (MC2) (MC2). (MC1) (MC1) (MC1). (B4) (B4). Development of biocompatible microbatteries. Biocompatible microbatteries that use. gastric fluid as electrolyte have been. proposed as power sources for ingestible. sensors, to measure vital body functions. such as body core temperature, pH, and. pressure. Such microbatteries do not need. encapsulation, enabling smaller and easier-. to-swallow systems. However, so far there. have been no solutions that allow realization. of such small-scale batteries with existing. microfabrication techniques.We have. developed and demonstrated working prototypes of microbatteries with Zn anodes and Ag/AgCl. cathodes (cf. Fig. 1). For this, we adapted existing microfabrication techniques typically used for MEMS. devices, which should enable further size reduction and a smoother transition to mass production. The. microbatteries were tested in simulated gastric fluid and exhibited cell voltages 0.9 V, sufficient to power. Fig. 1 Biocompatible microbattery prototype. The capacities correspond to operating times of a few minutes. The inset shows a microbattery with Au- contacts consisting of a Si microreservoir capped by a SiO2 wafer, onto which the electrodes are deposited.. 69 研究活動報告. an ingestible sensor device. Current capacities of the tested microbatteries and bare electrodes. correspond to operating times of 8–20 min, a consequence of the thin (~3 µm) electrodes. In a next step,. we plan to use thick film techniques—including 3D printing—to fabricate microbatteries that can be. powered for longer durations (a few hours) and also to develop biocompatible microbatteries that can. be used for other applications.. MoS2/. (HER) MoS2/ HER. MoS2/. HER. MoS2 MoS2/ HER. HER. LiCoO2. -. 研究活動報告 70. 2018.1 2018.12. , , ~2018.3 ,. 2018.7~ ,. ~2018.3 2018.10~ ,. 2018.11. , ~2018.3. ~2018.9 , ~2018.9 , LIU Mei,. , HO Hsing-Jung 2018.10~ ,. ~2018.3 , ~2018.3 ,. ~2018.3 , ~2018.3 ,. PAN Hsiang Wei ~2018.9 , , ,. , 2018.4~ ,. 2018.4~. , 2018.4~. 2018. JOGMEC. ~2017 3. 71 研究活動報告. JO. GMEC. As(V) FeSO4 Fe2O3. pH. HBr HBr. 2018. AgBr. COSMO-RS (COnductor-. like Screening MOdel for Realistic treatment of Solvents. 2018. J. OGMEC. 2018. 研究活動報告 72. 201. 8. ~2018 3. pH. 30. , 2018/5/24. 30 11 , 2018/7/23. 30. pH , 2018/11/6. 2018 , 2018/8/27. 2018 , 2018/9/1. 73 研究活動報告. :. :. :. :. :. :. :. :. 2018. CdS. CdS. ON-. OFF. (ITO). TCO. TCO TCO. 研究活動報告 74. Ce. C2. ( ). (PEFC). Pt. Pt. Ni Co PEFC. Pt. 75 研究活動報告. 2018 1 2018 12. 2018. 1.. 2014 -CuGaO2. 1.47eV -CuGaO2 -. NaGaO2 Na+ 2018 CVD -. NaGaO2 -NaGaO2. c -NaGaO2. Na : Ga = 0.83 : 1 Na. NaOH. -NaGaO2 mh 1. m. m -NaGaO2. CuCl -CuGaO2. -NaGaO2 -CuGaO2. LiCl 350 °C Cu Li. -(Cu1-xLix)GaO2 2 -(Cu1-xLix)GaO2. x 0.9 x~0.9 2.9. eV Cu Li -CuGaO2. -CuGaO2 -LiGaO2. -(Cu1-xLix)GaO2. 0.9<x<1 Cu. x<0.9 Cu 3d. XPS. 2.. Ni 130. 250 ~ 450 nm Ni 3 a. 1 CVD. -NaGaO2 SEM. -NaGaO 2. Substrate. 2 -(Cu1-xLix)GaO2. x= 0 0.23 0.47 0.70 0.88. 研究活動報告 76. 20mT 3 b. Ni-B Ni-B. Ni-B. 3 c. 3.. 250 500. 2018. 32. 2.8 < O/P < 4.1 Tg. 160 620 °C. 10 11 ~ 10 3 Scm 1. 4 Tg. 2×10 9. 2×10 7 cm2V 1s 1 5. 4×10 10 cm2s 1. Tg Stokes-Einstein. 10 19 cm2s 1. 9. Tg. 300. 210 Tg 2×10 7. cm2V 1s 1 1×1022 cm 3 300. 0.7×10 2 Scm 1. 3. a b Ni c Ni Ni-B. NaBH4. (a) (b) (c). 5. 4. 77 研究活動報告. 2018 1 2018 12. SLiT-J. 2018. B 183 eV B-K. 183 eV. Ni C/N 300-005 200 eV. N2.3 Ce Ni CeO2 38 nm. Photon Factory. BL-11D. 183 eV = 6.76. nm = (sin +. sin ). +1. 1. 87.07° Ni. 13.8% CeO2. Ni = 84.85° 28.2%. 2. 3.6. X CCD Photon 10. 1 CeO2 Ni 183 eV. 研究活動報告 78. Photon Flux. X 10keV. Tl:CsI > Eu:GGG >. Ce:LYSO > Tb:LSO > Eu:YAP Ce:YAP > Ce:YAG Ce:LuAG Eu:CaF2. Eu:GGG > Tb:LSO > Ce:LSO > Eu:YAP > Tl:CsI > Ce:YAP. X X. (EUV). ImPACT (JST) EUV. 100nm. EUV. 2018 EUV. CCD. EUV. EUV. 100nm EUV. 2. 2 EUV. 79 研究活動報告. 2018.1 2018.12 . . 2018.4 2016.3 , Aryal Bikas,. , 2018.4 , 2018.4 2016.3 2018.4 . . 2018. . (q) EELS LaB6 . TEM. (q). EELS. q EELS. q. LaB6. EELS q. qEELS LaB6 (a), (b) LaB6 E-q. q (a)q//100, (b)q//110 (c). q (a)(b) q2. LaB6 q q2 (c). q2 LaB6 . . Ba Sr2Nb2O7 . Selected-area electron di raction (SAED) and convergent-beam electron di raction. (CBED) techniques were used to reveal Ba doping e ect on crystal structure of (Sr1 xB. ax)2Nb2O7 (SBN) in the temperature range from 293 to 693 K. Ba doping to Sr2Nb2O7. 研究活動報告 80. (SN) causes a weakening of an in. commensurate modulation and a d. eviation from C-centered lattice. O. n the other hand, symmetries of f. atterns of SBN were seen as the. same with those of SN, showing t. he small structural deviation from Cmc21 ( 2). Crystal symmetries. above and below the temperature. of a relaxor-like dielectric anomaly. in SBN (x=0.32) at 465 K remai. ned unchanged. CBED experiments with a nano-meter sized electron probe did not sho. w any indication of a presence of nano-domain at around the temperature. A few micro. n size polar-inversion domains have been found at around 573 K in SBN (x=0.32). The. origin of the reported relaxor-like dielectric anomaly in SBN (x=0.32) is discussed on t. he basis of the experimental results of CBED. . . X DLC . Diamond-Like. Carbon; DLC DLC. sp2 sp3. sp2/sp3. K. DLC sp2/sp3. XPS sp2/sp3. DLC C-K. 2 sp2, sp3. 2. sp2. (sp3) (sp3) c-Dia. X . 4 8. K 3. 81 研究活動報告. 1 2. CNF. CNF. 1 CNF CNF. 2. CNF CNF 2. 2. CNF CNF. CNF 250. nm CNF. CNF. 2. CNF CNF. 2. 2 MnZn. MnZn. JEM3000F. 2 MnZn (( ). B40 ). B40 90. 180. 1 CNF CNF .. 2 MnZn (( ) B40 ). 研究活動報告 82. 3. 2. (FIB). FIB. 3(a) FIB. (b), (c) (a). (b). (c) 2. (d). 18 V 0.1 V. 2. 4 LiNbO. LiNbO3. FIB. FIB. Ga. 300 kV JEM-3000F. 4. 5. 2 5(a). 5(b). 5(c) 4 mT. (b). 5(d) (c). 3 (a). (b)(a). (c)(a). (d)(b). 4 LiNbO3. 5 (a) (b). (c)4mT (d). 83 研究活動報告. 2018.1 2018.12. Shahed Syed Fakruddin. Hou Jie Trung Nguyen Tat Wang Yu. MD. Iftekharul Alam HOSSAIN Mohammad Ikram. 2018. 1 (MoS2). FET /. FET. FET. MoS2. MoS2 SiO2/Si /. MoS2-FET MoS2 2~4 SiO2 285 nm. CuPc H Pc. 400-1000nm. MoS2. MoS2-FET UV/Vis. CuPc 2. 600 700 nm. 619 nm, 675 nm. UV/Vis Q 618 nm, 682 nm. H Pc. CuPc H. Pc HOMO LUMO. 研究活動報告 84. MoS CuPc H Pc. 2, 3, 7, 8, 12, 13, 17, 18-octaethylporp. hyrin (OEP)-TbIII double-decker complex, (TbIII(OEPH)(OEP)). TbIII(OEP)2 TbIII(OEP)2. TbIII(OEPH)(OEP) STM. 1.5 V. TbIII(OEP)2. TbIII(OEPH)(OEP). TbIII(OEP)2. 85 研究活動報告. 2018.1 2018.12. , Huie Zhu, Ali Demirci (~2018.6). Md. Mahbubul Bashar, SoYeon Kim,. YongJoon Im, , , ,. Chang Fu, , , Manmian Chen,. Weijie Ma, ,. , Teh Thian Tiong. (LB). 2018. 1.. PMMA PVA Nylon6 HKUST-1. Cu(OAc)2. benzenetricarboxylate(btc) 1. HKUST- GIXD Nylon6 HKUST-1 (100). pDDA (111). HKUST-1. HKUST-1. HKUST-1. 2.. (SQ) N- (DDA). (p(DDA/SQ)-b-pDDA) UV. SiO2 SiO2. SiO2 SQ p(DDA/SQ) pDDA. SiO2. SQ Langmuir–Blodgett. UV SiO2 FT-IR X. (XPS) SiO2 AFM. (QCM) SiO2 pDDA. ( pDDA) SiO2. 研究活動報告 86. X (SAXS) SiO2. pDDA pDDA. p(DDA/SQ26). SiO2. 3.. Poly-3,4-ethylenedioxythiophene/Poly(4-styrenesulfonate) (PEDOT/PSS). PEDOT/PSS. PEDOT/PSS. 2. ( ). 1-. t = 10 PEDOT/PSS. S. S. PSS PEDOT. 4.. (NDI). NDI. PAMAM-NDI4 Langmuir-Blodgett(LB). PAMAM-NDI4 pDDA 80mol%. X. p NDI NDI. 40°. 5.. - ZnO. Si 6 h. 18±9% 400 nm. pH. 87 研究活動報告. 6.. ( ). (LbL). (PEI-Fc) (N-. succinimidyl ferrocenecarboxylate) ITO PEI-Fc /. polystyrenesulfonate (PSS) LbL 9 cycles PEDOT:PSS. ITO –. Fc 7.9 mol%. Fc. Fc 15 mol% Fc. Fc Fc 20 mol%. (18 ) Fc. Fc. 7.. Si-O. P-R. 8.. Simultaneous control on selective formation of ferroelectric crystal and nanostructuring in ferroelectric. poly(vinylidene fluoride) (PVDF) materials have attracted intensive interests for high-performance and low-. energy consuming electronics while remains unfortunately a challenge. In this study, a facile preparation of PVDF. homopolymer nanoparticles (NPs) showing monodisperse size distribution and predominant ferroelectric(FE). phases was realized in a solvent (DMF)-nonsolvent (water/methanol)-polymer (PVDF) ternary system through. nonsolvent induced phase separation. Increase of the water content in the nonsolvent caught a structure evolution. from porous membrane, membrane wrapped NPs to pure spherical NPs. The as-prepared PVDF NPs were. characterized with the predominant FE phase even up to 98.4% which is a breakthrough in PVDF homopolymer. NPs t. 研究活動報告 88. manipulated when an external force was added to the DMF-water-PVDF ternary system which generated even the. domain size of 6 nm.. 9.. A supramolecule connected by multiple-hydrogen-bonding was synthesized through linking the UPy groups to. heptamethyl-cyclotetrasiloxane (HMCS) bearing one Si-H reactive group. The synthesis was started from a. reaction between 1, 6-diisocyanatohexane (NCO) and UPy with 97% yield. UPy-NCO was reacted with allylamine. (98% yield) and o-nitrobenzyl chloride was attached to protect the carbonyl of UPy groups (77% yield). Finally,. the protected UPy-NCO-Am-NO2 was bonded onto the ring of HMCS by the Pt-catalyzed hydrosilylation reaction. of olefins and Si-H to obtain the final product bearing multiple-hydrogen-bonding units. The chemical structures. of all products were verified through NMR, FT-IR and MALDI-TOF/MS. Thermal properties were detected using. TGA and DSC, which shows that the melting temperature at 100 oC corresponds to the dissociation of UPy dimers,. and glass transition temperatures at 20 oC and 45 oC match cyclosiloxane segment movement and dissociation of. H-bonding from urea groups, respectively. Microscopic phase separation was confirmed using AFM in the HMCS-. UPy-Am-NO2 spin-coating film. In addition, a lamellar structure was also observed from X-ray diffraction pattern. with a d-space of 3.8 nm indicating a molecular level phase separation.. 89 研究活動報告. 2018.1 2018.12. :. Edward Van Keuren Georgetown University. 2018.3.21 2018.4.14. : Chanon Pornrungroj 2018.9.30 , Grasianto. 2018.9.30 , , , ,. ,. /. 2018. PDA (3)( ). PDA DA. DA. PDA PDA NTs. PDA NTs PDA NTs Au. NPs PDA NTs. PDA NTs PDA NTs. Au NPs Au NPs Au NPs. PDA NTs 3 Outer Outer/Inner Inner PDA NTs. Au NPs . 1. Outer Inner 90 Au NPs PDA NTs. Outer/Inner PDA NTs (3)( ). FOM. Outer/Inner FOM. 28. Outer/Inner. Au NPs .1 PDA NTs. Au NPs. Outer/. Inner. 研究活動報告 90. P3HT. FTS. P3HT. P3HT FTS 60. I-V FTS 0.1 L. 10 . 2 Van der Pauw. FTS. P3HT. XRD edge-on. (100) P3HT. 2 = 5. FTS. XPS S(2p). FTS. P3HT FTS. P3HT. LSPR. LSPR. Au NPs. PDA Au/Silica/PDA HyNPs. PDA Poly(ADA) Au NPs Bi-Phasic. Au NPs. PDA. Au/Silica/PDA HyNPs HyNPs. 140 nm PDA 25. nm 3 nm STEM/EDS. 5 .3 PDA 0.05. 1.2. 1 = 0.06 ns (73%),. 2 = 0.20 ns (27%) 1 = 0.04 ns (77%),. 2 = 0.12 ns (23%). .2 FTS. P3HT. .3 Au/Silica/PDA HyNPs. PDA NCs. 91 研究活動報告. 2018 1 2018 12. Mohammed Ouzzine 2018.7.31. 2018.4.1 2018.11.1. DC3. 2018. (KB) N234 (N234) 2. ( )-Ox. ( ). (Avicel PH-101 Sigma-Aldrich). 180 °C 1 h HPLC. 1. KB N234 KB. N234 N234. 120 m2/g KB. 1296 m2/g 856 m2/g. N234-Ox KB-Ox. KB. CO CO2. 1.. 研究活動報告 92. KB N234. KB-Ox N234-Ox 1. N234-Ox 800 °C CO 600 °C. CO. (CNTTs). (TPD) TPD CNTTs. PBS 0.1. TPD 450 800 ºC. m/z 16, 26, 27, 44. 25 nm CNTTs CNTTs25 , 60 nm CNTTs. CNTTs60 AqCB. -PBS 1 mL. TPD. T ThT CNTTs. HCN m/z 27. 5 pmol 1.25 nmol. TPD 30 g CNTTs25 CNTTs60 AqCB. 2. 60 min CNTTs60 78 %, CNTTs25. 68 %, AqCB 50 % 60 min. A. CNTTs60 A. CNTTs25 1.7 A. 14 ThT 3 A. 30 g CNTTs60 CNTTs25 AqCB. 2 CNTTs25 CNTTs60 90 g. ThT TPD A. 30 g CNTTs60 78 % 90 g CNTTs25 87 % 87 %. A . CNTTs A CNTTs A. 2. CNTTs25, CNTTs50 AqCB. 3. CNTTs25, CNTTs50 AqCB. ThT. 93 研究活動報告. 研究活動報告 94. P-E. S R. S R. R. S R. S R. S. S. g. g. glum. S R. S. S. 95 研究活動報告. 2018.1 2018.12. ( 2018.3) (2018.4 ). (. 2018.9) (2018.7 ). (NIL). NIL 2018. NIL. NIL Al CH3 3. H2O SVI saturated vapor infiltration. 1. 2. STEM-. EDS Al Al. CH3 3 1. Al 2. Al. 100nm. SVI. Al. Al. Al. Al. Al. Al. Si. Si. O O. O. OH. O O. O. OH. O O. O. O O. O m nm+n=2.3. Monomer chemical structures comprising UV-. cured resins and illustrations of Al-mapping. images of UV-cured resin thin films after vapor saturated infiltration with Al(CH3)3 by. STEM-EDS.. 研究活動報告 96. (UV-NIL) print-and-imprint. ( =11.0Pa s). polyimide. ( 532nm, 12.5ps 1. 10kHz 0.1s). PEEK(9.0 m) (9.0 m) < PI(9.3 m) < PPS(11.7. m). NIL 15nm 15nm. 5nm. 7, 15, 20nm. 7nm. 15nm. 0.001. 0.1. 10. 1000. 0 10 20. surface-surface distance (nm). v is. c o. u s p. a ra. m e. te r. (N s m. -1 ). O. O. O. O. O O O O. O. OH O. OH. O O O O. O. OH OH OH. O. Increase in viscosity at different nano-gaps between silica surfaces. depending on chemical structures of monomers.. Optical microscope images of laser-drilled. through holes on a laser exit surface of PI,. PET, PPS and PEEK films at a repetition. rate of 10 kHz.. 97 研究活動報告. 2018 1 2018 12. Anh Thi Ngoc DAO. , Farsai Taemaitree, ,. ,. ,. 2018. 2- -D- 1. 2- -D- 1. Low Pressurized Hot water conversion method (LPH ) Fig. 1 2- -D-. 140 22 C-. 5. 2. 3. 2. LPH 2 E1 (PGE1) (4). PGE1 (4) Fig.2 5. 10 2. PGE1 (4). O. OH. OH. HO HO. O. OH. HO. H2O. O. OH. OH. +. 2-Deoxy-D-glucose (1) 2 3. Al2O3 H2O. 2. 140 °C, 22 h 80% from 1. Fig. 1. LPH 2- -D-. Fig. 2. PGE1. O. NEt2. TBSO. >10 steps. OH. O. HO. OH. O. OH. 6 steps. 5 PGE1 (4). 研究活動報告 98. HPLC. (R )-. 2 (R )-2 3. 6. PGE1 7 (Fig. 3). 2- -D- 1 2 (R )-2. 3 6 PGE1 7. PGE1. 2. Fabrication of Au/silk nanoparticles (NPs) for drug delivery in cancer treatment.. Drug delivery technologies has been quickly innovated in last few decades, especially in aspect of. combination with nanotechnology to advance into multifunctional drug carriers, which can accomplish. targeting a tumor, delivering therapeutic molecules, imaging and monitoring drug response. Many. models were built and tested; still the challenge is at the choice of the appropriate materials and the. facilitation of carrier preparation to achieve both safety and efficacy.. Among the potential materials, silk has been used for medical applications for several centuries,. mainly as sutures and wound dressing mat, due to its remarkable mechanical strength and. biocompatibility. It is also because of these characteristics, scientists have started to develop silk-based. materials for tissue engineering and drug delivery applications and obtained greatly potential results.. The development of silk-based materials in the drug delivery field is still new but strongly growing due. to its great potential. In a short amount of time, many research and successful results have confirmed. silk to hold great promises as a drug carrier, and the effort to nurture and bring this material to practice. has been non-stopped. Especially, the state-of-the-art of silk-based materials in drug delivery could be. named as silk NPs with pH-responsive drug release, led to its usage as a lysosomotropic anticancer. nanomedicine. Meanwhile, the controllability of NPs structures and properties (higher order structure,. surface net charge, functionality, etc.) has not yet been achieved.. At the same time, gold (Au) NPs have been extensively studied for drug-delivery system due to its. unique plasmonic properties, which can be. utilized for not only cancer. detecting/imaging but also photothermal. destructive therapy or thermal-responsive. drug release. More importantly, the high. surface area and the strong interaction. between Au and thiolate group making the. grafting of targeting molecules. straightforward and robust. In this report,. Au NPs and silk NPs were fabricated in aqueous (Fig. 4) to investigate and manipulate its stability and. compatibility in biological environment. As the next step, hybrid NPs of Au/Silk will be prepared to. utilize both components’ strength in drug delivery application.. Fig. 3. PGE1. O. OH. HO. O. NEt2. TESO. (R)-2 6. 3 steps. 1) -chain. 2) -chain. 3) Desilylation. O. HO. OH. O. OMe. PGE1 methyl ester (7). 99 研究活動報告. x x x. ZT. xTr x x. Tr x ZT. x x x. x x x, x. ZT. x x x. et al. Adv. Mater. et al. Chem Mater. 研究活動報告 100. a b. c C m. a b. c Cmcm. c. x x. a c P mcm. c. a c. P c. 101 研究活動報告. 2018 1 2018 12. E A. ,. D3: , D2: Fred Labib, M2: , ,. , M1: , , ,. , , , , , Fred Labib. 2018. 1. -AlCuRu. -AlCuRu F i-AlCuRu 12. Pm-3 , J. Alloys and Compd 299 (2000) 169. 100. R3. <111>. {001} {001}. {001} {110}. 研究活動報告 102. 2. 2. NO+CO N2O+CO. NOx (NO, N2O). CO NOx Rh Pt Pd. NO+CO. NO+CO N2O+CO. Cu Cu2O CuO 2(A). Cu CuO Cu2O. Cu Cu2O CuO. XRD Cu2O CuO Cu0. CO NO+CO, N2O+CO. Cu0. Cu2O Cu2O(I) CuO CO. Cu Cu* (< 300oC) NO, N2O Cu2O*. 2(B). 103 研究活動報告. 3.. (X2YZ). (Furukawa & Komatsu, ACS,. Catal. 7 (2017) 735) X Y X Y Z. ( : X2YZ1–xZ’x). (Kojima. et al., ACS Omega, 2 (2017) 147). Pd (CnH2n–2)+H2. (CnH2n)+H2 (CnH2n+2)+H2. Co2MnGe Co2FeGe H2. +H2. H2 :H2 =. 1:10–20 :H2 = 1:400 H2. Pd intrinsic. (Co2MnxFe1–xGayGe1–y). Mn-Fe Ga-Ge. 研究活動報告 104. Anung Riapanitra(DC3) Angga Hermawan(DC2). (DC1) Ardiansyah Taufik(DC1) (M2). (M2) (M1) (M1). (B4) (B4). (2018.8 ); (2018.10 ); (2018.10 ). 105 研究活動報告. (a). 研究活動報告 106. 107 研究活動報告. Ca4+xY3-xSi7O15+xN5-x Si7(O,N)19. 2018 1 2018 12. 2018.9 , 2018.10. Hong Phong DUONG. PEG-P. PEG-P. 20% PEG-P. PEG-P. PEG-P 12% PEG/P 1 2. PEG-P NaCaPO4:Eu2+. PEG-P PEG-P. 30% Ca/Eu. PEG-P. CaO-Y2O3-SiO2-Si3N4. Ca4Y3Si7O15N5. Ca4.5Y2.5Si7O15.5N4.5 Ca5Y2Si7O16N4. Si7(O,N)19 Si. Si 3. Si. 研究活動報告 108. Ru/SrTiO3:Rh. BiVO4. Ru(PD). Ru/SrTiO3:Rh. (IMP ). Ru/SrTiO3:Rh Au, Ru. Rh 2. Ag. Ru(PD). Au Ru(PD). Ru. BiVO4. BiVO4. BiVO4. TiO2 WO3. BiVO4 BiVO4. BiVO4. SrTiO3:Rh. BiVO4. 109 研究会報告. 研究会報告目次 2018(平成 30)年 1月–12月. 1/11 企画講演 2『次世代放射光施設計画の推進状況』 ·················································111. 1/15 2017年度ベースメタル研究ステーションワークショップ·······································111. 1/19 International mini-symposium on molecular and hybrid materials ·································112. 1/19 多元研国際セミナー：Edwin Kukk教授講演会 ·····················································113. 1/19 平成 29年度東北大学多元物質科学研究所附属先端計測開発センター講演会 ············113. 1/31 多元研国際セミナー：Wendell Hill III教授講演会 ·················································114. 2/23 2017年度第 1回拠点･アライアンス博士課程学生グローバル研究力養成道場 ·············115. 3/2-3 金属資源プロセス研究センター国際シンポジウム (IMM2018) ·································117. 3/27-28 JST ERATO百生量子ビーム位相イメージングプロジェクト中間シンポジウム ··········119. 4/6 高分子・ハイブリッド材料研究センター講演会 ···················································122. 5/14 2018年度第１回拠点･アライアンス博士課程学生グローバル研究力養成道場 ·············123. 6/9 第 29回万有仙台シンポジウム『未来を指向した有機合成化学』 ·····························125. 7/24 第 4回MaSC技術交流会〝Real Exchange″ ························································126. 7/27 International mini-symposium on advanced materials ················································127. 7/31 Mini-Symposium on“Electronic and Structural Dynamics” ·····································128. 8/2-3 5th Joint Workshop of Case Western Reserve University and Tohoku University ···············129. 8/8-12 ISHA2018国際ソルボサーマル・ハイドロサーマル協会国際会議 ····························133. 8/10 2018年度第４回拠点･アライアンス博士課程学生グローバル研究力養成道場 ·············134. 8/23 Neoprotein Biology – From synthesis to trafficking ···················································136. 9/13-14 第 1回非鉄金属製錬セミナー ···········································································137. 9/18-19 第 10回金属産業におけるダスト処理・エネルギー・環境に関する日本–ブラジルシンポジウム ············································································································139. 10/17 高分子・ハイブリッド材料研究センター講演会 ···················································142. 10/17 平成 30年度東北大学多元物質科学研究所附属先端計測開発センター講演会 ············143. 10/24 2018年度第７回拠点･アライアンス博士課程学生グローバル研究力養成道場 ··········144. 11/1-2 第 6回アライアンス若手研究交流会 ··································································146. 11/12-13 第 27回素材工学研究懇談会『材料特性と顕微鏡観察技術の最近の動向』 ·················148. 11/18-20 窒化物半導体国際ワークショップ ·····································································149. 研究会報告 110. 11/29 多元物質科学研究所放射光産学連携準備室第１回ワークショップ ···························150. 12/10 高分子・ハイブリッド材料研究センター講演会 ···················································151. 12/14 イノベーション・エクスチェンジ 2018·······························································152. 12/21-22 第 11回酸化グラフェンシンポジウム ·································································153. 12/26 第 1回東北７大学次世代放射光学術シンポジウム ················································154. 111 研究会報告. 企画講演 2『次世代放射光施設計画の推進状況』日時： 1月 11日（金） 9:00-11:40 場所：福岡国際会議場（A会場）. 平成 30年 7月 3日の文部科学省発表により、官民地域パートナーシップによる次世代放射光施設（軟Ｘ線向け高輝度 3GeV級放射光源）の推進に関し、同施設の整備・運用の検討を進める国の主体である量子科学技術研究開発機構とともに、整備・運用に積極的に関わる地域及び産業界のパートナーとして、一般財団法人光科学イノ. ベーションセンターを代表機関とする、同財団、宮城県、仙台市、国立大学法人東北大学、及び一般社団法人東. 北経済連合会が選定された。これにより、放射光コミュニティが長年にわたり議論してきた 3GeV放射光施設が、国のプロジェクトとして本格稼働しはじめることになる。計画の進捗状況と今後の展望について報告する。. 司会内海渉（量子科学技術研究開発機構）. 1. 「次世代放射光に対する期待ー量子ビーム利用推進小委員会の立場からー」雨宮慶幸（東京大学） 30分. 2. 「国の主体としての次世代放射光計画への取り組み」内海渉（量子科学技術研究開発機構） 30分. 3. 「次世代放射光計画におけるパートナーの役割」高田昌樹（光科学イノベーションセンター・東北大学） 30分. 4. 「加速器設計の進捗状況」西森信行（量子科学技術研究開発機構）渡部貴宏（JASRI・量子科学技術研究開発機構）田中均（理化学研究所・量子科学技術研究開発機構） 30分. 5. 「学術及び産学連携における次世代放射光の位置づけ」有馬孝尚（東京大学） 30分. 6. 「まとめ」 10分. 2017年度ベースメタル研究ステーションワークショップ『固液界面での接触と反応をどのように制御するか』. 高炉プロセス等の高温反応プロセスでは還元、溶解といった固液間の反応の制御が求められる。この時、反応場. である接触界面には物理的および化学的な力が働くが、その相互作用については十分解明されていない。製鉄プロ. セスのようにこれまでに検討が重ねられてきたプロセスでは、さらなる反応の促進目指すためには、新たな視点か. ら「現象を視る」ことが必要であろう。融体物性制御による反応の制御という観点から本ワークショップでは話. 題を募った。反応と物理的現象の関係について知見を広げるために、多くの皆様に議論に参加していただきたい。. 日時： 2018年 1月 15日 14:30 ‒ 17:00 場所：東北大学多元物質科学研究所事務棟大会議室. 主催：東北大学多元物質科学研究所ベースメタルステーション、. 日本鉄鋼協会製鉄プロセスフォーラム. 共催：附置研究所間アライアンス、日本鉄鋼協会東北支部. プログラム 14：30－ 14：35 趣旨説明など東北大学高旭 14：35－ 15：05 二融体界面に生成する微粒子と形態制御に関する研究北海道大学夏井俊悟 15：05－ 15：35 固液界面の移動現象を利用した拡散係数の評価東北大学川西咲子 16：55－ 16：25 非平滑面固体と液体の動的接触現象東北大学植田滋 16：25－ 16：45 海外研修報告：コーヒー滓燃焼灰からのリン回収東北大学小泉匠平 16:50 ‐ 総合討論東北大学助永壮平. 研究会報告 112. Invited Lecture. Invited Lecture. 113 研究会報告. Edwin Kukk教授講演会. 多元研国際セミナー（多元研主催、アライアンス／共同研究拠点共催）講師： Edwin Kukk教授トゥルク大学（フィンランド）日時： 2018年 1月 19日 16:30-18:00 場所：多元研西２号館 3回セミナー室参加人数： 15名講演題目： The new MAX-IV light source and its possibilities from the viewpoint of. Finnish-Estonian partnership. 平成 29年度東北大学多元物質科学研究所附属先端計測開発センター講演会「計測とデータ科学の協奏」. 日時：平成 30年 1月 19日（金）13：00-17：00 場所：東北大学・片平さくらホール 2階主催：東北大学多元物質科学研究所. 共催：東京大学放射光分野融合国際卓越拠点、理化学研究所 SPring-8センター、理化学研究所創発物性科学センター、. 物質・デバイス領域共同研究拠点、. 人・環境と物質をつなぐイノベーション創出ダイナミック・アライアンス、. 一般財団法人光科学イノベーションセンター. 先端計測における放射光科学をはじめとする近年の計測科学の進展に伴い、物質・材料科学、生命・医工学な. どの各分野では、高解像度イメージング、動画イメージング、マルチパラメータの実験データなど、多様かつ大. 量の計測データが得られるようになり、それらを効率的に解析し、物性や反応性の理解と制御に活用するという. ニーズが高まっています。一方、データ科学の分野では、巨大で複雑な科学データに潜む構造 (semantics)を人間に理解可能な形で抽出する技術、データマイニングとシミュレーションが急速な進歩を遂げ、科学的な計測デー. タ群にも適用されつつあります。. 本講演会では、計測科学の進展によりもたらされた知見とデータ科学の物質・生命科学への展開を紹介し、両. 者の融合がもたらすであろうデータ駆動型科学、マテリアルインフォマティクス・バイオインフォマティクスに. 向けての展開について議論する予定です。. プログラム. 「低エミッタンス放射光源の可能性 -高輝度・高コヒーレンス性の活用 -」東北大高田昌樹「相反する複数機能制御による創発物性の課題」東大/理研 CEMS 岩佐義宏「固体触媒材料の不均質性に基づく反応性可視化と課題」名大唯美津木. 「人工知能技術による機能分子・物質設計」東大津田宏治. 「材料科学のためのデータマイニングの可能性」北陸先端大ダムヒョウチ. 研究会報告 114. Wendell Hill III教授講演会. 多元研国際セミナー（多元研主催、アライアンス／共同研究拠点共催）講師： Wendell Hill III教授メリーランド大学（米国）日時： 2018年 1月 31日（水） 16:30－ 18:00 場所：多元研西２号館 3回セミナー室参加人数： 15名講演題目： TProbing Quantum Dynamics from Femtoseconds to Attoseconds. (Abstract:) Unambiguously identifying, tagging and following quantum trajectories during charge migration in molecular systems. is central to understanding molecular dynamics and the key to unlocking solutions to robust control techniques necessary to address contemporary scientific and technical challenges. Photo-induced charge