研究業績・活動報告2011

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(1)東北大学多元物質科学研究所. 研究業績・活動報告 2011 年 (平成 23 年)12 月.

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(3) 多元物質科学研究所. 研究業績・活動報告目次研究活動報告 ·············································································· 有機・生命科学研究部門 ········································································································. 1 1. 無機材料研究部門 ················································································································· 15 プロセスシステム工学研究部門 ······························································································· 29 計測研究部門 ······················································································································· 45 サステナブル理工学研究センター ···························································································· 61 先端計測開発センター ··········································································································· 79 高分子・ハイブリッド材料研究センター ··················································································· 87 窒化物ナノ・エレクトロニクス材料研究センター ······································································· 101 寄附研究部門・研究ステーション ···························································································· 113. 研究会報告 ·················································································121 学会発表講演目録 ········································································151 有機・生命科学研究部門 ········································································································ 151 無機材料研究部門 ················································································································· 154 プロセスシステム工学研究部門 ······························································································· 157 計測研究部門 ······················································································································· 162 サステナブル理工学研究センター ···························································································· 165 先端計測開発センター ··········································································································· 168 高分子・ハイブリッド材料研究センター ··················································································· 170 窒化物ナノ・エレクトロニクス材料研究センター ······································································· 174 窒化物結晶寄附研究部門 ········································································································ 177. 研究業績目録 ··············································································178 有機・生命科学研究部門 ········································································································ 178 無機材料研究部門 ················································································································· 180 プロセスシステム工学研究部門 ······························································································· 186 計測研究部門 ······················································································································· 193 サステナブル理工学研究センター ···························································································· 197 先端計測開発センター ··········································································································· 205 高分子・ハイブリッド材料研究センター ··················································································· 207 窒化物ナノ・エレクトロニクス材料研究センター ······································································· 213 寄附研究部門・技術室 ··········································································································· 216. 業績目録著者索引 ········································································217.

(4) 1. 研究活動報告. !"#$%&'()*+,%-. !"#$%&'. .2011. 1/2011. 120. 1 2345 6 7 1389:;<=>?@(2011A4B/) CDE=F3?G HI J * K !3LMN O<PQR;(/2010A3B)<S-TU<VWX Y<Xiao-Guang Chao<Z[\]<^_`!<a?bc (2011A4B/) _+,%-defg#)*hijkl#$m%&hnop'(q<rsthuvwxy&z{h) *|l}~ zhqw+,hwvA_+,l+, qwefLls ()* +,-./01234516789:;<=>?@ABCDEFGHIJ >+,de|xy&l qw¡'¢h£(q<¤E|¥¦l§¨©ª«¬®¯° l qw±²|l³g´'h£(µ¶·¸¹º¶»¼½¾¿l(ÀqwvÁ QR* S@%&T<+,/01234516789=>?@ABCDEFGHIJNUV* +,u]^_vwNxyzGH*. i/jklmnopqrsN tb19-.*. %&'()*+,-./0123456789 Target mRNA. O. N. N N. N DNA. K{*|}~ ;xy z. OMe. (W*KXYZ[\]^_`KYabc dYefgh31*. B. d*|}~ N xyz*. +,T<u]^_:;=> @GHT<xy z*. AAA….. X. B. H N. N H O H. X. + Firefly /renilla activity. O. A. O. N. O. miR21 target. Luc2. m7 G. 4. !". 3 2. #$. None Oligo. 1. A. ÂAÃeÄÅÆ¼½huvÇÈÉÊlxy&z{}~lËvwÌÍhÇÎÏÐÑÒÊ dÓÔÕ'(ÖhuvwÄÅÆ¼½h×ØÙ¸Ú’ÛÜÝÞ©ª«ßàálVvÓÔÕz{âã±ähå Ä<æçÄèémÙ¸Ú’ÛÜÝÞ©ª«eê©ª«lëWèéqÇ´ä<ìvÓÔÕ'(híîÄ ïðtñlqÇtlÐÑÒÊlvwëWèéqÇê©ª«huvwÈÉÊl±ähÌÍq Çr´ä<°¯òº®jóÓÔÕôjõö÷lèéqÇê©ª«hÈÉÊløùÄd<ÓÔ Õz{h±²úâãÄ<tl<êû©ª«|ü¥lëWèéýÇê©ª«eêû©ª«´'h âãqÓÔÕz{m)hîÄÄhðtñlqÇëWèéýü¥lþ<ÓÔÕz{ âãæçm)h}~dÿÄeàál. !"v. K)* LM+,-./0123451678N-./OP #AÃ<|$%&Jtle±²)hqw<'(lå(ËëWèémµ¶·¸¹º¶» ¼½h)ÇlnoqÇÂAÃeÄstµ¶·¸¹º¶»¼½ëWèémlËvw*ÈlÌÍq Ç.

(5) 2. 研究活動報告 uvwxyz+m*{|+}~GHIF# H O. N H DNA. O. N. H N. N. N. N. N H2N. DNA. h ij')QRSTUVWX .YZS[\I]^_àG HI.bcde.fg# # h klm)nLoQpqrP )nFGHI.st#. H. DNA. NOP+QRSTU VWX.YZS[\I ]^_àGHI. bcde.fg#. O. O. N H. N N. N. H N N. N. DNA. O. . #. MeOOC. !"#$%&'()*+,-./0 1!23456!7!686! !945:;<:=434>45?@ABCDEFGHI# 2 !"#$%&'()*+,'-.!/0123456!7819:;<=>6?@A=BCDEF GHIJKL!MNO RNA HP1Q=RSDH45NO;:TUVW9XYZHIJKLHPNO 456[=Zn, Ni E\3]^3_`Hab`cYdO;:TUVW9X u w$%&'()*+,-./0ABCD@ EF~GHI# BQRcnI# N=. 5’d(CCGCT 2 TCGCCG)3’ 3’r(GGCGA N AGCGGC)5’. O. NH2 N. 80. HO. 60 20. N. U 6. 12 18 Reaction time (hr). O. N. O. N. N. OH. N. N. H2N HO. 40. O 20. 4. CA. 2. O. MF#. Zn Ni. G. Yield (%). N O. 100. 40. Yields (%). NH2. z+F QpqGH. OH. 0. 24. 24 h. YZHIJKLHP1QeZd9f`g3hijkHlmQno19:;<=4HpNhiqrO;: TpYd9X. ! #7!23456!#! !945:;<J=45?#@7!BADEKLMFGHI# stuvwxygz3{!"#$%&'()*+,'-.!/01=23456!7819X23|}= ~6?@Aq[BCDEFGHJKLIJKLHP1Q=YZH>6?@q[BCDEFGH IJKLL!l uuHP1Q456!l;:TUVW9X2;q45 Y9=IJKLJKLLHPNOf`g!1u ttu!k19| }=T`Yd9f`ghi3 T¡Yd9XYZH¢£Ehijk!no19 T=eZd9f`g[m¤d¥¦§kqrb¢£Ehijk!¨©;:[qªEVW9X uw7!BAD@EF~GHI# 4Â 5a: 6b:. (A)DNA target pH 5.0. (b). pH 7.0. NH2 N. (a). N. pH 5.0. O. (b) pH 7.0. N= 40. dG 20. Yield (%). dA. 30. dC 20. A 20. 10. 20. Reaction time (h). 10. R2 COOR1. C. 30. O. 20. A. C dA 10. N. G N=. 30. dC 10. N. 40. 40. dG. N= 30. O. N=. Yield (%). 40. Yield (%). MF#. (B)RNA target. Yield (%). (a). uw7!BAD@EeeF. CCGCGT X TCGCCGÄ’ ÅX: 3Æ Ä’ dÅGGCGCA N AGCGGCÆtFAMÃ’ Ä’ rÅGGCGCA N AGCGGCÆt FAM Ã’ Ã’. 10. 20. Reaction time (h). G. 10. 20. Reaction time (h). 10. 10. 20. R1=H or CH3, R2=5a (N=dA) R1=H or CH3, R2=5a (N=dG) R1=H orCH3,,R2=5a (N=dC). Reaction time (h). «=«¬qHeZd9m®¯!l°L(±²L³´456µ~!¶mQ£·¸H¹ºO »¼½¾¿À!noNOÁkqrOX 1) Nagatsugi, F., and Imoto, S. Organic & Biomolecular Chemistry 9, 2579-2585 (2011)..

(6) 3. 研究活動報告. !"#$%&'. !"#$%&'()*+,-'2011(1)*+,,(12-!. .. /! 0! 12! 34!. 5. .! 0! 67! 89:! ;<! =>!. ? @ A B! 0! CD! E:! FG! HI:! J! KL:! MN! OPQ:! ! ! ! ! ! ! ! ! ! ! DR! ST:! UV! WX:! Y2! ZB:! [! \]! !!!!!!!!!!!!!!!!!!!!!!!!! < "^_à DNA b RNAcdefghijklmBnFôpqrsthuvwxhyz{|}t~ p bpcBnôppeF^ jy ¡¢£¤p¥ec "#$I¦f§¨©2011 ªp "#$efac«¬ p®¯°±¨© ! ()*+,-./01234567-89:;<=>?@ABCDEFGHIJKLMNOPQIJKL OPQRST UVWXYOP*Z[\[R]*A^_` \ST abcdefg \Shij*k #l2mno!"* ² "³àc´L µ¶l·¸ ¹º»?µ¼½`¾¨qrsp¿ÀoÁÂÃÄÅecÆÇÈ o¨ÉÊ RNA pËnÌÍÎÏpÐÑlPÒ¨ÓÔÕvÖ×Ø (PRNA)p¥I¦ f§¨©PRNA aÙÚØÛÜnÝÑ¬cpH ÆÇÈoe miRNA b mRNA lmÉÊ RNA ÞÒ¨ßà ÊËnÌÍPec¿ÀoÁÂÃefpF§ßáPef§¨©eâe RNA pËnaãäåpæ¢ á`cRNaseH pçklè·§lmc§·éâpêëÒì¾íîâl¦f¾©ïp®lðñòóôc ² "³à DNA bÓÔÕ×Ø(PNA)lmc×ØÛÜnõoeföôc÷¿ÀoÁÂøùú lûáüýÊâéþÿÊ !"#$123456789:+;<.=#>?@<AB CDEFGHI JKLMNO6H#PQJ1RSTU"#VWJKXBY!+Z[\])^& _`Dab)^c?#>?@ <Bd+ef mRNA ISghi RNaseH SjkI <lm#1PRNA I DNA1PNA nLMNO6#$%&+ ,-./0Bop2H+;qrcJ1stuvKw<YJ'J1xSop2C D (P R PD)y1z{:/|236}L ~]1 & RNA I egh#=@<Bd1 U RNaseH "S y] BY y 1> S _ `D a b l IJ K S r+ f : { M : .~ # T@ < PRNA-PNA-DNA op2CDSrc1u +;q¡)* .=HS1RJK¢£.=¤ in cell ]S_ `Dc?¥¦§r@<Bd1>S¨:©ªk«O¬_`D#Ö®¯I@<op2CD#.=J1RS "#JBY°±:-{M:.~#T@< PRPD S.=²³S¡)*´µ¶´+(wKJ BY·h&+y1DNA i¸¹ ºj"»¼½]¾¿ÀÁ¿ÀjIJKÂ:Ã96jÄBz jÅ#ÆÇJ1Bz ¿À PNA LÈÉÊS.=#JËÌSSÍ^1¡ÆÇ&¡)*+¾¿ÀÁ]1op2.=+I K)^& LÈÉO¤SÎÏ+=ÐJBY Ñ vB Bz-PNA #Uw1Luciferase #«O¬@< mRNA #&~IJB116 ºjS PRPD #.=J1Ò& DNA Ó+ RNA +Ô@<gh=¥¦ÕÁ+(wKJBY_`DablIJKef RNA IS U#JBIxÖ1PRPD×DNA ghS Tm +ØÙ RNA ISghS Tm y1nÌ20ÚÛÜÝÞXÜßà J1PRPD y RNA !á&+gh#=@<xIiâ 'I BYã+~ä!á& endonuclease ]< RNase H +;< PRPD×åæç RNA ghSèé"#JÍ^1PRPD Sèé\Sêi DNA +ØëJ Kì 2 íÛÜÞXÜ BY°B1îØ' ïðJBÖ:ñOòOó' PRPD iZ[&+ÕÁ@<xIi â '+ BY xv SÍ^#j+1siRNA +;qc?ô¥iõöuv< Luciferase .=#Uw1sir-830 S÷9¬#Ö® ¯IJB PRPD +;< Luciferase cæøùÕÁ+(wKJBÍ^ in cell +úwK RISC =ûüiÁIw ýÞþÿ !wÍîÑ vBY.

(7) 研究活動報告. !"#$%&'()*+,-./0123456'789:;/'<=>?@AB" ! '()* pH +,-./012*3456789.:;<=>[email protected]#G,HEIJK LMN.OPQRSTBJKLMNPU*VWXYZ[MW\]^_`5ab7cdI "ef.ghij7k lmBC.6nI/012?opJKLMNTBqrDE*stDEuvwx.yGz{|}y~Q5 HEIOP_Y A?F7k "iTB_pJKLMN OP.12?o0z 7 iB89./01256A#G,HEIDEGJKLMN.zA7kli 5B_p'JKLMN (Split GFP) 5 ¡p'¢?G0*34¢??o0z£Q5 ¤,¥7 56Ay¦§¨.'(){*B34©ª«5aA'¬.®¯z°¥ GFP +~t .±²z³A´mkµ¶TB_p'JKLMNzm·L^¸#G¹º»[¼5uAB¤½ ·L^¸.¾¿·À^Á{¹ºzHE ¥7Â.RSz³m (Figure)k.ÂiTB_p GFP a 6Ã YFP . N ÄÅÆÇÀÈÉKÊ (GFPN a6Ã YFPN) 5ËB~I7·L^¸.ÌNÍÎzÏ¯B ÐÇÀÈÉKÊ.! N- a6Ã C- ÄÅzÑÒ¥7 iÓ,A7ky¦.·L^¸©ª«BÓÔ,ÇÀ ÈÉKÊ.ÌNÍÎ0Fy~Q5ÕÖ BC ÄÖ× .ØÙFHE IÚBÛ¯ ¥7·L^¸5Ü©m'JKLMNÝ Þ.'»ÈV¿FßàmklmB¤½ ·L^¸.áÁ{¹ºâHEijmk µ<TB»[¼zsqr5ã¥7 iB {|}y~QIstäå\[æ^¸#G¹ ºÂ5ç7è¦ij7k C!"34DEF/GHIG/JKLMNOPDQRSDTUTUEJVWXYZ[/\]2'<". /mdeg. sté_ij7êë*JKLMN ì_ .íîïz£ð¥7 iBñò.óôõ öF7â . A7ksté_.÷Àø[ù5ú¥7 Bsté_-ì_íîï56ÚBì_.' Uûü5ýþG(CD)Fÿ 7kCD zé!5¹º¥7 56ÚB"#i$%&h'q5sté _-ì_}íîïz¹º¥7 FHEij7FBCD (MÊ¿z)*¥75T+,Qé-.³x F.dij7 Fá/B³x015g¦.23F âInsté_. "5 AB44.d5. "#z06¥7 523F7nkli89F:;A´m<ý='z7 CD ¹ºÂTB<ý='. <ý>z?KÊ\^¿¥7@ALÀÉ^JB='B(C)Bz?KÊ\^¿¥7 iBDE¬.F&bG. ®HB¥II CD .é!¹ºFHE5I7 èàAmkCD .¹º!.JGTBà¦5K¥7 LKå¿5.MN5hIFÚB@G.æOXK[^] I7k ¶TBP¶Þ5Q´R´é!Sé{}_ðEzT¥7 CD à¦UVz¥7 â5Bóm5BP ¶@Wm<ý='zmé! CD ¹ºÂ.XYzZ[.ýþG_\²õ?¥7 56AB li.ýþGà¦.$]zÎhhé!ýþGà¦Võ ç7 z³mkC.m_B `_'abcd.efz*AB`_'gýþG 3000 PEM Voltage _\²hJ-820izjkBý='slmij7'nG 2500 140 mV +0ohPEMi.pqz?KÊ\^¿¥7 iä0.ý 200 mV 2000 250 mV 400 mV ='z<ý=' BJ-820 .'¹ºÂzC.llK 610 mV 1500 Normal CD ¥7 iBé! CD à¦o.@Wz³mk 1000 ÙrBs5°¥6n5 PEM 5tu7pqz«vB£w G<ý>zé/¥7 BCD (MÊ¿.F&b.¬F 500 ®¬¥7 Fxy& Imkµ<.UVzzã, 0 260 280 300 320 340 ¥7 iBóôIé! CD ¹ºoõ hIF7 {u Wavelength /nm y7k CD spectra of ammonium (+)-camphor surfonate in H2O with various PEM setting in J-820 spectrometer.. 4.

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(15) 12. 研究活動報告. '()*+*(,-(./0123456789:;6<=>?@:;6ABC,DE?@:;6FBCGHIJ CGKLMNOP0QRS7'(,-(TU0123S<VWXM*YZ[\?0]^3_`.Xab3Sc\_ d*e*XfghijXklmXab3Sc\OP0no456< ! VWX_d*e*ab(+IpCq0r$[s6tHquv0wx3_,-yz{W 60ms |Xd*e*0a bs6J}~v03S<_`* GN* :( "0no456< !"#$%&'()*+,+-./0123456-789:;< F~B)*+*(,-(_12{W 40:,-,xNX3 43S<3{3_40:,-,xN: 3S<8¡¢£¤jO¥y OP¦:O§_0¨©67ª«¬#3_VWX8(IN0®¯,°g±s87²£³:;687²´{ oS<µ(¶·²g¸¹0º»X¼67_}~Lt½X345687²´{g_µ(}~Lt(¾'V ¿¾N{WzÀs67 11 7O6<8( 11 75ÁÂÃÄ/(¯7`Ås6<Æg_XfgÃÄ/ ²)*+*²£¤jXÇÈs6870ÉÊ3456< ! VWX_»Ë(ÌÍÎG»ËÏÐ(Ñ Oxford ¾( Richard Berry. 7(ÒÓ ":ÔW{X3. 456<8¡W(¥0ÕÔs6)ÖN0×:;6< ! =!>?@ABCDEFGHIJKL$M< ! ØÙÚÛ»ËÜÝXÞ54ßàáOPâãOäå0æs<8(º»XÆ54_µ(ÇçèjG éjX. "V¡4'S²_ê»ËdëN(. "ìí:5O5<îïðØÙÚÛ»Ë(¼ñ{W. òó4_#0ôoS»Ë(¼ñõö(÷¶0noS<øX_ùúûN)C:;6üNýþÿ BC0QRS !("#$%&(y[0123S<µ('(_üNýþÿ BC0QR4¯)|X"#$%²3_ê) ¹:*oS<S_+,½-XÞ.6»Ë/0(y[0123S789_123 ¹(/0( 012:'S<8({W( 4 »Ë(x,&¸5Xx6V¡456Â7Ó`:;oS<VWX_ ê»ËdëN:(,120nÁSóX_ÒÓ. "Xfg_FI7+N89C:dF*0;5S120noS<µ. ('(_ûN)Cùú|X`¸(9C:dF*(yÎ012s687²:'S<ûN)CO3:(/0<z :µ(fÁOùú²O587{W_ØÙÚÛ»ËXf6x,:;6870æ=3456<! ! VWX_>lm12Xfg_»ËXf6x,¥7µ( 07WR687X?@3S<8(¥0AO[è BTC:ÕÔs687X?@3_DÄ¯0EFÑ687²:'S<! ! N!OPQ R-STU6-VWXHYZ[\]:^< ! GHI XpJJC)/0ÃÄ3_µ(0KLM;34N$s6:C)/(N$0ÇO3S<µ('(_ N$ª?P7Ó.(Qg0Rs687X?@3S<VWX_GHI STXd*e*0hijXUV3_ µ(!(:C)/(N$0123S<µ('(d*e*ab×X:C)/(Qg²3_d* e*ab0Wó67_Qg²XXYoS<8('(_d*e*Xf6 GHI (Q,G#[² GHI 6Z (pJJC)/X[]V¡_#[V¡S870æ=s6<_Ö*+¯0\W3_d*e*]{W(^È OP0_`×:;6<!.

(16) 13. 研究活動報告. !"#$%&'((. '()*+,-./0 ")12201131420113125! !"#"$%"&". ' +. !"#"()"*" "#",-"./". *0123"#"456"78" 9 : ; <"#"=>"?@AB%"CDA6E"FGAH>"IA" JK"LMA$%"NOAPQ"RSATU"V" ! W12XYZ[\]^_àbcdefghij:aklmniopqrsatu12vwkxy zdg{|dp}12~gpxy2011 a12~[ avy !"#$%&'()*+,-./01 2 3456789:;<3=>? \]^_`[q<h<y}vefg2aefXZyW 12XYZ[q\]^_`p}mn ¡y¢£¤q\]^_èfg¥¦§y¢ £g¨X©ª«Z¬§y®¯°±a²¥dtug³xy´µ¶Za12Zq\]^_` g·:¸Bv¹º»¼v¨X©ª«Z½¾¿¬§y}aÀpÁ±ZyÂÃÄÅÆÇÈÉ± g²¥p} Ê¶[ÂÃÄÅÆÇÈÉ±v qËÌÍsaÎÇ_ÃÏ c dÐÑy\]^_àv Òx¨X¾ÓÔÕºgÖqa×ÍØÙ«ÚÄÛ-goÜp}ÎÇ_ÃÏ c [qÝÉ Þßàváâãäp}åÏgæçXèdpxéÒêë`ZyzaìíîïÃðìíñvò·ó ôgõª«p}nvqvö÷y¾ÓÔøÄ\g¬Õpqùúû9:a4üý !n² ¥p} LES ±vþxoÜp}ÿaã Aa!v"Òa#$xö q#¿ Z%v&'§yzdg(nmvp}#aX)g*+§yzdZq¿a×ÍØÙ«ÚÄ ,g-./yzdZynvq#¿a&')[ 01|2 äa34g5}pxö q&'ØÙ«Ú Äg-./yzd/Z} )aoÜg¸vpxqÎÇ _ÃÏ c avö÷y×ÍØÙ«ÚÄÛ-g[6 x78zd9fvþ}î: 1 )ñ ;6¬ÕgqåÏgé}<=ðaÎÇ_ÃÏ c vÒ x/ÖqåÏaâ>ØÙ«ÚÄÛ-v?@yA g BCp}óôgõª«p}ÎÇ_ÃÏ c mnDE|vå ÏgF G}ìíguHpq¨X¬ÕdøÄ\a LES oÜgÖþ}ÿaã qåÏgF G}v/IJn¼q ïÃðdKL§y"Òa#MyN¶XOZ¬ }î: 1 ñïÃðd<=ðZKLp}#Pn }ã mnqåÏaQRbcaSv #<6} aZ[zdãTZy}qUaËÌÍsaÎÇ _ÃÏ c vÒx/qKLp}#Pnxy )a*+[qVàbcMy"Òa#ÎÇ_ÃÏ c aWváXpxYZ§yzdg[\§y )avq¨Xò·¬guyzdZq 6 789:/;< = >?@ABCDEFGHI a\]^_à]goÜ§yzd9fvþ}" JKLMNOPQRST;UPVRWXYU " CZ[\]^_àbcdeP! ".

(17) 研究活動報告. 14. !"#$%&'()*+,-./0123456789:;*7<=" !"#$%&'()*+,-./01234-56&7"89:;4-LG<*=>?@AB0CDE F*GHIJKLM,N4-LG O3PQRSTKUVW:X6YZ[\3]^*_àKbcde] f-g\hibjKkdl0mnop2qeNl*W:X6YrstK5uR13vwxyoz{o peCDEF0wx|}*GH~KLM,N*3 *CDEFrV*wmd el0r.123pp*wZO?@^rm[el0mp,Nd-34-LG * *_r3?@^*-mM, 03:X6&Z?@^*- * VmdeNl*r3wx* Kde?@^KvwxQuRr q2I~13wx* Kw¡del0m¢£r-M,N >!"/0123?@7?;9A+BCDEFG7<=" vwxCDIJKL¤¥r¦CDst*§m¨©Z[eNªr3stm.*«q¬® ¨¯ r°±1,¤¥r3²³yr´µ r¶dl0K·01,¸¹ºm»zp3vwxI Jr./p2qeN¼½¾w¿ZO3ÀÁ*¸¹º0OÂ-ezÃre+Ä¸¹º*»zKLM ,Nd-3ÅÆ_*ÅÇtK¬®¨¯ *È-6É:ÊË#012/q,Ìr3 012ÍÎev¨¯ÇtK¸¹ºr\&5'(deN30 ÏÐÑÒ*Ó¥ÔKÕÖ1,0123 9-×:&5Ø:ÙRÚ:ÇmCDst*ÛÜKÝÞßdl0Kzà1,Nor39-×:&5Ø: ÙRÚ:Ç*á/âSmv¨¯Çt*&5'(Z[el0K1,N " H!">IJK 79A0LM+NDOPQ/01?@RS7<=" vwxCDIJ*H`wã£KäÒ{e,å*æç*è)01235é:!ê#Ù%ë*ìíî ïðñK»z12,NÀÁ*îíîë*ìíîïðñKò¤¥3vV*CDstmó|H`ôr zdeCDDx^rõ\m[e,å3vö9÷Ñ ø*ùH`wã£*I~Oú1q0ûüop2q ,NýþO3ÅÇt*øZÿ K!1-m ovwxI~KL03"#$%mrÝÝv &ÑÒ*H`wã£*äÒm¢£Z[el0Kà q'1,N$*(²*H`wã£O 30 )s Z[ eNor¦swDI~K¢£r1,N l**}K/qel0Z3+&6", c¦(" -é: A¦.R&#%¥W:X6Y-/*0é 1ö6%*I~KLM,N+&6", c *¤¥3 ÿ m^2.é6"÷yo^ö9÷3F*H`% 4#RZ51ÝSTÓKL6xmIJp,N 7op,8#WO3+&6", c * r 9eçcÉ:R;#<`m=yq>?KUVl0 ' ()*+,-./0123456789:;'< Kk@12qeNvAZ3 r 9e(" -é: A *¤¥O3«H`wã£*I~rBCoDCDEF*H`ÓO[G\I~p-yM,N l*O3+&6", c rH2STmóI-("-é: A *¤¥rO¦É:R;#JmKoy Z[el0Kk12qeNor3 .R&#%¥W:X6YrVq23ÝZ[e.R&#%m ¥deL3KIJ1,0lM3l*W:X6YO-ST*NOvKk1-moB3ÈP rÝ*¥KLl0Kàq'1,N ÑÒ*r3vwxIJ*}K/q23GQG-W:X6YrVq2*HRS8#WKT7d el0m¢£r-M,Nor¦LES ãUKòM2HRS8#WKwUdel0Z¦VWYX0rÂ -eY0ìYdeYrVq2*Z[m¢£r-M,Nl*-I~Kor\]1z^{e _Z[eN.

(18) 15. 研究活動報告. !"#$%&'(. ()*+,!"-./2011.102011.121 ! "#$% & ' ! "#() *+ , !#-. /0 12345#67 89 :;345#< =>? @A BC D E F G#HI J? KL D? M7 NO? P@ =Q? 6R OS. T34UVWXYZ[\]^_àbcdbeafghijklmnbopY[\]^_bqrstu v\wbxyz{|bst}~34z H23b34Xbi~z )* +,-./0123456789:1;<3!"( bR~hY[\]6bX[z [\]6bafu ~izeagX¡¢W£¤YT34UVWXq~¥¦§g¨c©ª«¬g~®¯Y°±² 34z ©ª«¬eagX³´µ¶b·©ª«¸b©ª«¬¹º»b¼®½¾¿~ÀÁYÂ bUÃÄbÅÆŸ¥¦§g¨cÇlÈÉÊ¦Ë²U¿ ÂbÌÍ~XY&Î»bÏ ¨ÐV~ÑYeaÌÒuÓÔÒbÕÖ¯²~×¥¦§gopY&ØÙÚz TXY HfbÛ©ª«¬eag~izZrU¿b&ØÙÚc Ü]W~¦ÝnÞßàÙÚWáâc×¥¦§Û©ª«¬eaãäŸåæ6HfçZrè éê]10000mass ppmëìícîb7_ïu&ØÙÚ&ðc eacHfCl4-HCl³´µ¶ HfO2ñòYeaóôWbZrê]Äõc eaôbHfO2öbZrê]ç÷HfÄëX70mass ppmW£¤Y¦ ÝnÞßàÙÚWø¶cùúÄ100uû}büýcçùúÄ100bþÿYv\w100Ub1~. ¶!". #ò$zë ×¥¦§Û©ª«¬eagX%&~é¨W£¤YZrê]#'WW()b[\]HfO2# ø¶c =*(>?@ABC0DEFGHI(JKHL1237MN456789BC( ULSI*+[,-./©nba½op~XY[016»b2¢î×3YÂb4~Xv\w5). í. c[\]6#6d¶z ³s7b89:#)[016b[\]eaguXY;^k¦<È³ s(HPAM)=R>ß§³s(EBM)#éü?@z HPAMXYD9:Wb³sgW£z~îAB¶ CYEBM*+[DE³suûF~89:b[6v\wb8pùúGj¾H}#I-W£z JÓX Mo÷K~YHPAMuEBM~iz³sea&ðYLgbeaÌÍ}ÄõMNc åæMo(>99.9%)7ï~YOPk¦<ÈQßÇ³sR~i¤S20T³seac k¦<ÈGUVn~X ArGj1W50XH2+ArŸv\wùú~÷!z;^Yhij³s7Zb{|MNc ûF~OP R>ß§³sRŸMo(S20g)bEBMc ³sóôbMoU[~XYGDMSGjv\rVn³0 gYH^Vn]^g}Ÿ_àv\wb^b) ícdefc HPAMWXk¦<ÈVn;^Y#5%ÖWgh*eaÌÍ#piYeaÌÍX;^Yjk~lÕ Öc#Ymnµ30XH2ä]#(îghW£c o²~XYMo~Äf89:#[×3b6v\w (Fe, Ni, Cr, Zn, Mn})#1 mass ppm~W8pùúYc¾HÌÍîpd¶c cqY89 :#)W}Xùú*µc rÍuY7ïMobÿsv\wê] (O, N, C, Wù3)S150 mass ppm XY30%H2+ArY³s7Z20UW5 mass ppm~W. t¶c $uYEBMWîû}*earÍ.

(19) 研究活動報告. 16. !"#$% &'()Mo*+,- ./&01232045Mo678509:;<=>?@A B#$%C D$=E?*+FGH$)?WI:JK L#$%CM$=NO&HPAM5PMo*+,-PQHR&Mo67 P989STUVW5&X7Y)01Z[\5]^MU _!H$%C `%&EBM=a^bcV:deXAfghO%CijV(eklm1.4mass%)n30gfop=&EBM(30kV, 0.25A)fqr%@A&eklmP012310450.63 mass%&20450.36 mass%=>sO&VW)de !"#$%Ctu&eklm:>s=a^bcV:vkwxyz{T=|}^~f~U5qr ?^C) mP&HPAM=a^V:defghO%?C !"#$%&'()*+,-" bcfm}Û&UPR)^f} #$?^CM$P:yz t$%UU #^5]&:yzf#=}^P&tuUPR)^%)p+:+=) ^C ¡¢£5y=m=¤¥)yzUO&¦§Yyz&ëyz ]^C mP&©ª«¬5]^mFe:¦§Yyz=?&®=¯°±²³´µ\f¶?&·¸¹º »¼½z¾¿=a^À±ÁÂ:¿Ã=?´µfqr%C·¸=a@Ä ÅRÃÆO%ÇÈ5P& D:É:ÇÈ=Ê¯°±ËÌ²³ 10psÍmÆR)&ÎÏÐÑÒ ÓRÔr?ÛÕ#$^C°± Öº¬×ØÙÚ(EBSD)=a^ÛÈ¬ÏÜ4Ý:@AÞ¯°±²³´µ:@AfßàO?^C`%&áâ ã¢£5P&ÑÒ 10äSTåæO%ÑÒçèéêë:ìu íH$%CmSî&H#=ïð)1ñ& `%É:@ò:mbc=|}^~fóôõµ5]^C ./#0123456789:;<(=>" :ö÷©p(GaAs, InGaAs, InP, PbSI)PøùbcÐúûübcfýÃþkU}^Cÿºà ! ")#$f%&}T5&D:'(p:+P)*5]^C+,P-./ 015&2345:ù)?67 89:òö÷©:+f;"?^CmP&<=g>?UO@AH$^MnSi1.75UMg2SiB@f mopf¶?C[O&DÃO%B@:@zÐEF/=?GHO%C ?@ABCDEFGHIJKLMNOP!QR:;<(=>S MnSi1.75PIJõKLn0.8eV:MN:OPQRfàö ÷©5]^CMnSi1.75=£?MnSi1.733:C[S TUH$?^ &IJVW#&M:XÃ5Pö÷©UP )#)?C MnSi1.75 XÃ:B@fYµOC[}^PZ[5]r%CDM5&~5P&\] ;^_\=a^@ÃÆ2=&];`:\a:4bfcd}^5&YµOMnSi1.75fÃÆHe^¬\ f_«O%CmSî&B#$%@:f\yzI=?GHfqgC ?TAUVW3XYZ[HIJKL\]NO:;<(=>S"mMg(him5N)UmSi(him10N) fop=C[O%Mg2Si@5P&M$`55j>:kP7llmfO%Cop:mMg=P&Al&S&Cl& Zn&PbI::mëzEF 0.1mass ppmSTn`$ &M$#EF:>s o)^kP7llm:> s=) Û@AH$^C R!"&'(^_`BIabKcd" In-situ4fp7Rqrs7ë\f¶?&CuÐNi)tmbcB@:>¡ef1ñO%CM$`5 eumv:ewxyìz&eum:@¬ÏyìzIf#=O%C`%&CuÐNi)tpze FUZnÐMg)t:nzeFf¿Ã}^{|5&eumv )^MUf#=O%CH#=@¬Ï Ueum:|}P&ewUbc3:~|zfÕ}^MU51O%C mP&:IJU~@AfÊ}^MU5&>¡e:~= ?RH$?^ èQsIJÐë7QIJ:Áf#=O%CDM5O?fýO&:IJ5P5 )r%bc:>¡ef!"=O%C.