JAIST Repository: 創薬に関する技術トレンドと研究開発プロセスへの活用
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(2) Technological Trends in Drug Development And Applications for R&D Process Hideji Tanaka School of Knowledge Science, Japan Advanced Institute of Science and Technology September 2005 Keywords: drug, research process, simulation, scientometrics, article The main focus of this study was the examination of the potential of a presented scientometric approach to reveal technological trends in the drug development and was the confirmation of their impact on the R&D process in pharmaceutical companies. During the above search it was expected that several concept for R&D strategy of pharmaceutical companies was to be addressed. We extracted the technological trends from PubMed because it is the most popular and the most authoritative database of medical articles. In the search typical key words representing each R&D process were used and the time-dependent changes of the R&D activity were examined. The evidence presented in this study demonstrates the increases of the articles including the key words we choose. The increasing rates of each pharmaceutical R&D activity vary substantially across development steps. The following R&D activities were strengthened: simulation for prediction of the probability to complete remaining phases and evidence and/or outcome to be proved as a true endpoint in the actual therapy. The pharmaceutical R&D process is not a fixed, rigid one. It has been modified to improve the success probability of the project. Using the scientometric approach we assessed the important R&D capabilities in pharmaceutical companies that were suggested in previous reports.. Copyright Ⓒ 2005 by Hideji Tanaka.
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金沢大学大学院 自然科学研 究科 Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa 920-1192, Japan 金沢大学理学部地球学科 Department
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＊2 Kanazawa University, Institute of Science and Engineering, Faculty of Geosciences and civil Engineering, Associate Professor. ＊3 Kanazawa University, Graduate School of
氏名 学位の種類 学位記番号 学位授与の日付 学位授与の要件 学位授与の題目
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* Department of Mathematical Science, School of Fundamental Science and Engineering, Waseda University, 3‐4‐1 Okubo, Shinjuku, Tokyo 169‐8555, Japan... \mathrm{e}
This research was supported by Natural Science Foundation of the Higher Education Institutions of Jiangsu Province (10KJB110003) and Jiangsu Uni- versity of Science and
