業績集　：　滋賀医科大学　内科学講座　呼吸循環器内科　第三代　堀江教授業績（４）学会発表（海外）2004～2014

業績集 ： 滋賀医科大学 内科学講座 呼吸循環

器内科 第三代 堀江教授業績（４）学会発表（海

外）2004∼2014

著者

滋賀医科大学 内科学講座 呼吸循環器内科

発行年

2014-08-04

URL

http://hdl.handle.net/10422/7178

業

績

集

滋賀医科大学

内科学講座

呼吸循環器内科

学会発表（海外）

【２０１４】

 Miyamoto K,Aiba T,Kimura H,Hayashi H,Nakajima I,Ishibashi K,Okamura

H,Noda T,Kamakura S,Kusano K,Horie M,Shimizu W.Electrocardiographic Characteristic of Flecainide Therapy for Ventricular Arrhythmia in Patients with Andersen-Tawil Syndrome with KCNJ2 Mutation.Heart Rhythm2014(2014.05.06～11,San Francisco,Ca,U.S.A)

 Hasegawa K,Ohno S,Kimura H,Itoh H,Makiyama T,Yoshida Y,Horie M. Mosaic

KCNJ2 Mutation in Andersen-Tawil syndrome:Targeted Deep Sequencing is Useful for the Detection of Mosaicism.Heart Rhythm2014(2014.05.06～11,San Francisco,Ca,U.S.A)

 Kawata H,Funasako M,Ishibashi K,Nakamura I,Miyamoto K,Sakaguchi

H,Miyazaki A,Okamura H,Noda T,Aiba T,Kusano K,Kamakura S,Shimizu W,Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) associated with Ryanodine Receptor (RyR2) gene mutations:Long term prognosis after initiation of optimal medical treatment.Heart Rhythm2014(2014.05.06～11,San Francisco,Ca,U.S.A)

 Sonoda K,Watanabe H,Nogami A,Ohkubo K,Makiyama T,Takehara

N,Kawamura Y,Hosaka Y,Sato M,Fukae S,Chinushi M,Oda H,Okabe M,Shimizu W,Kimura A,Maemura K,Watanabe I,Kamakura S,Burashnikov E,Antzelevitch C,Horie M,Aizawa Y,Minamino T, Makita N.Genotype-phenotype associations in early repolarization syndrome.Heart Rhythm2014(2014.05.06 ～ 11,San Francisco,Ca,U.S.A)

【２０１３】

 Ohno S, Hasegawa K, Makiyama T, Doi S, Horie M. Different regulation of IKS

channels by two KCNE 1 C- terminus variants predicts the QTc response to the exercise stress. The Heart Rhythm Society's 34th Annual Scientific Sessions (2013.05.08-11, Denver, CO, U.S.A.)

 Itoh H, Berthet M, Fressart V, Denjoy I , Maugenre S, Klug D, Mizusawa Y, Makiyama T, Hofman N, Husemann A, Shimizu W, Wilde AA , Schulze-Bahr E, Horie M, du Montcel ST, Guicheney P. Asymmetry of parental origin in Long QT syndrome. European Human Genetics Conference (2013.06.08-11, Paris, France)

 Ohno S, Omura M, Kawamura M, Kimura H, Itoh H, Makiyama T, Ushinohama H, Makita N, Horie M. Exon-3 deletion of RyR2 encoding cardiac ryanodine receptor related to left ventricular non-compaction (LVNC) with ventricular arrhythmia and bradycardia. EHRA EUROPACE 2013 (2013.06.23- 26, Athens, Greece)

 Itoh H. Underlying Mechanisms in Forme Fruste Long QT Syndrome

Manifested by Acquired Factors. The 2nd HD Physiology International Symposium (2013.06.28-29, Tokyo, Japan)

 Ashihara T,Haraguchi R, Inaba S,Nakazawa K Ikeda T,Ozawa T,Ito M,

Trayanova N,Horie M.Functional properties of complex fractionated atrial electrograms during atrial fibrillation can be explained by structural remodeling:A simulation study.(2013.08.07-10,Glasgow, U.K.)

 Fukuyama M, Wang Q, Kato K, Ohno S, Kimura H, Makiyama T, Itoh H, Ito M,

Matsuura H, Horie M. Novel CACNA1C mutations in Long QT syndrome patients- The subtype of Long QT syndrome type 8. Denis Escande Symposium 2013(2013.8.30-31, Amsterdam, The Netherlands)

 Ohno S, Fukuyama M, Itoh H, Makiyama T, Horie M. Copy number variation in

KCNQ1 gene were frequently identified in the pediatric patients of long QT syndrome and caused exercise related QT prolongation. ESC CONGRESS 2013(2013.8.31-9.4, Amsterdam, The Netherlands)

 Kokunai Y, Kino Y, Li M, Itoh H, Nakamori M, Kimura T, Matsumura T,

Fujimura H, Nukina N, Sakoda S, Horie M, Imoto K, Ishiura S, Swanson MS, Charlet-Berguerand N, Takahashi MP. Altered splicing of cardiac sodium channel might be responsible for cardiac conduction defects in myotonic dystrophy. the 9th International Myotonic Dystrophy Consortium(2013.10.16-19, Basque, Spain)

 Horie M: Genetic and Molecular Basis of ARVC. VT Workshop 2-ARVC Session.

6th APHRS & CardioRhythm 2013.(2013.10.03-06, Hong Kong, China)

 Horie M: Genetic Testing in ARVC. Genetic and Inherited Syndrome 1-Update

on Clinical Applications of Genetic Testing. 6th APHRS & CardioRhythm 2013.(2013.10.03-06, Hong Kong, China)

 Ohno S, Wang Q, Hasegwas K, Itoh H, Makiyama T, Horie M. Phenotypic characterization of three patients with lethal arrhythmia related to KCNH2-R148W missense mutation. 6th APHRS & CardioRhythm 2013.(2013.10.03-06, Hong Kong, China)

Horie M. The High Prevalence of Early Repolarization in Genotyped Long QT Syndrome. AHA Scientific Sessions 2013．(2013.11.16-20, Dallas, Texas, U.S.A.)

【２０１２】

 Takada S, Hashiodani K, Fukumizu Y, Yamauchi H, Sakai H, Horie M: Automatic Detecting Stenotic Murmur Method for Portable Medical System based on Time-domain PCA and EM Algorithm. 2012 RISP International Workshop on Nonlinear Circuits, Communications and Signal Processing (2012.03.04-06, Hawaii, U.S.A.)

 Ashihara T, Haraguchi R, Inada S, Nakazawa K, Ikeda T, Ozawa T, Ito M, Horie M, Trayanova N: Theoretical basis of optimal strategy for CFAE-targeted ablation during chronic atrial fibrillation. The Heart Rhythm Society's 33rd Annual Scientific Sessions (2012.05.09-12, Boston, MA, U.S.A.)

 Makita N, Makiyama T, Seki A, Nogami A, Ohkubo K, Watanabe I, Shimizu W, Watanabe H, Sumitomo N, Horie M, Delmar M: Clinical features and genetic basis of 63 patients with progressive cardiac conduction defect. The Heart Rhythm Society's 33rd Annual Scientific Sessions (2012.05.09-12, Boston, MA, U.S.A.)

 Kimura H, Ohno S, Itoh H, Kawamura M, Naiki N, Wang Q, Makiyama T, Ito M, Horie M: KCNJ2-R218Q/W is a hot spot with strong phenotype in Andersen-tawil syndrome. The Heart Rhythm Society's 33rd Annual Scientific Sessions (2012.05.09-12, Boston, MA, U.S.A.)

 Hisamatsu T, Miura K, Ohkubo T, Okuda N, Murakami Y, Miyagawa N, Horie M, Okamura T, Okayama A, Ueshima H. Effect modification of dietary n-3 fatty acids on cardiovascular mortality risk by resting heart rate in japanese general population: NIPPON DATA80. ESC CONGRESS 2012 (2012.08.25-29, Munich, Germany)

 FukuyamaM, Ohno S, Wang Q, Kimura H, Miyamoto A, Makiyama T, Itoh H, Itoh M, Horie M. Novel CACNA1C mutations identified in Japanese patients caused both Brugada syndrome and Idiopathic Ventricular Fibrillation without QT shortening. ESC CONGRESS 2012 (2012.08.25-29, Munich, Germany)  Horie M. Hypertension and atrial fibrillation involvement of RAS, role of

candesartan - The 1st International Forum of Wuhan Geriatrics Society 2012 (2012.09.22, 2012 Wuhan, China)

 Horie M. Inherited arrhythmia in Asia. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific

Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Ashihara T. Application of biological simulations to the studies of ventricular defibrillation. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Ashihara T. Mechanisms of CFAE-targeted ablation for chronic AF: A simulation study. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Sasaki K, Makiyama T, Wuryanghai Y, Chen J, Kamakura T, Kimura T, Yoshida Y, Yamanaka S, Ohno S, Horie M. One year assessment of ion channel gene expression in cardiomyocytes derived from human induced pluripotent stem cells. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Horie M. Acquired long QT syndrome. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Ohno S, Nishio Y, Nagaoka I, Fukuyama M, Kimura H, Itoh H, Makiyama T, Shimizu A, Horie M. Age dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Wang Q, Ohno S, Miyamoto A, Ding WG, Wu J, Kimura H, Itoh H, Makiyama T, Matsuura H, Horie M. Functional analysis of novel KCNH2. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Kawamura M, Ohno S, Naiki N, Nagaoka I, Dohchi K, Kimura H, Hasegawa K, Wang Q, Itoh H, Makiyama T, Horie M. Mutations identified in Brugada syndrome patients with or without ventricular fibrillation. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

Horie M. Genetic background of catecholaminergic polymorphic ventricular tachycardia in Japan CHA2DS2-VASc score and left atrial size are important to predict recurrence of atrial fibrillation after pulmonary vein isolation: usefulness of event ECG home monitoring. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Haraguchi R, Ashihara T, Inada S, Ikeda T, Nakazawa K. Rotational anisotropy prevents transition of tachycardia to fibrillation in ventricles under the large transmural dispersion of repolarization. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Hasegawa K, Ohno S, Itoh H, Makiyama T, Horie M. A Rare KCNE1 Polymorphism, D85N, is a Genetic Modifier in Congenital Long QT Syndrome. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Makiyama T, Sasaki K, Kamakura T, Shizuta S, Cheng J, Wuriyanghai Y, Ohno S, Itoh H, Horie M, Kimura T. Genotype-Phenotype Relationships in Patients with Familial Bradyarrhythmias; SCN5A Versus LMNA Gene Mutations. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Fukuyama M, Ohno S, Wang Q, Kimura H, Itoh H, Makiyama T, Ito M, Horie M. CACNA1C Mutations in Japanese Patients with Brugada Syndrome or Idiopathic Ventricular Fibrillation. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Fumimoto T, Fukuda M, Katoh T, Shimizu A, Ueyama T, Yoshiga Y, Masahiro Doi, Matuzaki M, Ohno S, Horie M. The Smaller R/S Ratio in Lead I is Characteristic of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia in Patients having Desmosomal Gene Mutations. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Kamakura T, Makiyama T, Wuriyanghai Y, Chen J, Sasaki K, Shizuta S, Hasegawa K, Ohno S, Horie M, Kimura T. Genetic Backgrounds in Patients with

Early-Onset and Familial Atrial Fibrillation. The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (APAFS) (2012.10.03-06 Taipei, Taiwan)

 Ashihara T, Haraguchi R, Nakazawa K, Ikeda T, Ozawa T, Ito M, Horie M, Trayanova N, Hopkins J. Functional Properties of Complex Fractionated Atrial Electrograms During Atrial Fibrillation Can be Explained by Structural Remodeling: A Computational Study. AHA Scientific Sessions 2012 ． (2012.11.03-07, Los Angeles, California,U.S.A.)

 Aiba T, Toyoda F, Makita N, Matsuura H, Makimoto H, Yamagata K, Horie M, Fukushima N, Ogawa S, Aizawa Y, Ohe T, Kusano KF, Yamagishi M, Tanaka T, Makiyama T, Yoshinaga M, Hagiwara N, Sumitomo N, Kamakura S, Shimizu W. Biophysical Properties of Na Channel in the S5-S6 High Risk LQT3 Mutations of the Long QT Syndrome. AHA Scientific Sessions 2012．(2012.11.03-07, Los Angeles, California,U.S.A.)

 Yagihara N, Watanabe H, Atack TC, Ohno S, Shimizu W, Chatel S, Koopmann TT, Ping Yang, Marylyn D Ritchie, Turner S, Hasegawa K, Wakasugi M, Onodera O, Kuwano R, Duboscq-Bidot L, Horie M, Schott JJ, Takayama M, Nakano Y, Bezzina CR, Wilde AA.M., Momotsu T, Endo N, Darbar D, Roden DM, Makita N. Arrhythmia-associated variants in the SCN5A promoter and regulatory regions. AHA Scientific Sessions 2012．(2012.11.03-07, Los Angeles, California,U.S.A.)

 Yamada Y, Sakaguchi T, Nakajima I, Miyamoto K, Okamura H, Noda T, Satomi K, Aiba T, Anzai T, Ishihara M, Yasuda S, Ogawa H, Kamakura S, Horie M, Shimizu W. Different response to exercise testing between Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia. AHA Scientific Sessions 2012．(2012.11.03-07, Los Angeles, California,U.S.A.)

 Kawaguchi T, Hayashi H, Miyamoto A, Yoshino T, Naiki N, Taniguchi A, Sugimoto Y, Itoh M, Murakami Y, Horie M. Prognostic significance of temporal increase in QRS duration and morphological development of QRS complex. AHA Scientific Sessions 2012．(2012.11.03-07, Los Angeles, California,U.S.A.)

 Hasegawa K, Ohno S, Itoh H, Hattori T, Makiyama T, Toyoda F, Ding WG, Chinushi M, Matsuura H, Horie M. Novel KCNQ1 missense mutation associated with juvenile-onset atrial fibrillation. AHA Scientific Sessions 2012．

 (2012.11.03-07, Los Angeles, California,U.S.A.)

Rosso R, Bhuiyan Z, Till J, Kannankeril P, Horie M, Knollmann B, Wilde A. Effects of flecainide on exercise-induced arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia. AHA Scientific Sessions 2012 ． (2012.11.03-07, Los Angeles, California,U.S.A.)

【２０１１】

 Horie M: Molecular genetics of ARVC. Cardiorhythm 2011 (2011.02.25-27, Hong Kong, China)

 Hisamatsu T, Miura K, Ohkubo T, Miyagawa N, Fujiyoshi A, Takashima N, Kadota A, Okuda N, Murakami Y, Horie M, Okamura T, Okayama A, Ueshima H. Interaction of Dietary n-3 Fatty Acids on Cardiac Risk by J-point elevation in Japanese Men: NIPPON DATA80. AHA Epidemiology & Prevention and Nutrition, Physical Activity & Metabolism 2012 (2012.05.13-16, San Diego, California, U.S.A.)

 Horie M: Genetics and Molecular mechanisms of ventricular tachyarrhythmia. Taiwan Society of Cardiology -2011Annual Meeting (2011.05.14-15 Taipei Taiwan)

 Horie M: Challenging ECG of sudden cardiac death. Taiwan Society of Cardiology -2011Annual Meeting (2011.05.14-15 Taipei, Taiwan)

 Kimura H, Zhou J, Itoh H., Mizusawa Y, Miyamoto A, Kawamura M, Makiyama T, Ito M, Matsuura H, Horie M. Phenotype variability in patients carrying KCNJ2 mutations. ESC Congress 2011 (2011.08.27-31, Paris, France)

 Sakai H, Kawahara C, Fujii M, Yamaji M, Ohnishi M, Matsumoto T, Wada A, Horie M. Effects of aliskiren on Left ventricular remodeling in patients with dilated cardiomyopathy. ESC Congress 2011 (2011.08.27-31, Paris, France)  Tsutamoto T, Sakai H, Kawahara C, Fujii M, Yamaji M, Ohnishi M, Matsumoto

T, Wada A, Yamamoto T, Horie M. Sitagliptin, a dipeptidyl peptidase-4 inhibitor, increases bioactive BNP level with the improvement of left ventricular mass index in patients with chronic heart failure.ESC Congress 2011 (2011.08.27-31, Paris, France)

 Hattori T, Makiyama T, Akao M, Ehara E, Ohno S, Iguchi M, Sasaki K, Itoh H, Horie M, Kimura T. Over-expression of heterozygous KCNJ2-M301K channels, identified in a patient with short QT syndrome, shortened action potential durations in neonatal rat ventricular myocytes. ESC Congress 2011 (2011.08.27-31, Paris, France)

 Ashihara T: Overview: Recent progress of the computer simulation and computed ECG. (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Horie M, Ohno S, Wu J, Zankov DP, Toyoda F, Ding WG, Matsuura H: Mutations of KCNE gene family in inherited arrhythmia syndromes. Special Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)  Horie M, Itoh H, Shimizu W, Hayashi K, Ohno S, Makiyama T, Yamagishi M, Kamakura S: Long QT Syndromes are heterogeneous disease entities presenting not only QT prolongation but multiple phenotypes - Cases with compound heterozygous mutations. JHRS-JSE Joint Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Horie M: Renin-Angiotensin-Aldosterone system and atrial fibrillation. Evening Seminar 1 (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)  Makimoto H, Horie M, Ogawa S, Aizawa Y, Ohe T, Yamgagishi M, Makita N,

Makiyama T, Aiba T, Kamakura S, Miyamoto Y, Shimizu W: Clinical and genetic features of japanese patient with congenital long QT syndrome. JHRS-JSE Joint Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)  Wu J, Naiki N, Ding WG, Matsuura H, Horie M: A weak dominant negative

mutation of KCNQ1-G269S affects PKA-Mediated up-regulation of IKs channels and causes adrenergic triggered long QT syndrome. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Naiki N, Hayashi H, Miyamoto A, Sugimoto Y, Ito M, Horie M. Prognostic significance of J wave in patients who underwent device therapy for ventricular defibrillation. Mini-Symposium (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Nakazawa Y, Ashihara T, Miyamoto A, Ozawa T, Sugimoto Y, Ito M, Horie M: Importance of long-term follow-up after pulmonary vein isolation: A study using event-ECG monitors. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合

同学会2011.09.18-22 福岡)

 Ozawa T, Ito M, Nakazawa Y, Ashihara T, Miyamoto A, Sugimoto Y, Yao T, Horie M: Ventricular fibrillation triggered during radiofrequency energy delivery for verapamil-sensitive idiopathic left ventricular tachycardia. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

W, Horie M: Clinical features and genetic basis of progressive cardiac conduction defect: Japanese PCCD registry. JHRS-JSE Joint Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Ashihara T, Haraguchi R, Inada S, Nakazawa K, Ozawa T, Nakazawa Y, Ito M, Horie M, Trayanova N: Mechanisms of complex fractionated electrogram-targeted ablation in a model for chronic atrial fibrillation. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Wang Q, Ohno S, Makiyama T, Kimura H, Naiki N, Kawamura M, Kato K, Horie M: Mutation analysis of the KCNJ8 gene in Japanese patients with J-wave syndrome and idiopathic ventricular fibrillation. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Nakashima T, Ohkusa T, Yoshida M, Yamada J, Okamura T, Ueyama T, Miura T, Shimizu A, Horie M, Matsuzaki M: New diagnostic test for arrhythmogenic right ventricular cardiomyopathy. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Taniguchi A, Hayashi H, Miyamoto A, Yoshino T, Kawaguchi T, Naiki N, Nakae I, Matsumoto T, Horie M: Relationship between nonspecific electrocardiographic abnormalities and left ventricular performance in coronary atherosclerosis. Poster Session(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福 岡)

 Yoshino T, Hayashi H, Miyamoto A, Taniguchi A, Kawaguchi T, Naiki N, Sugimoto Y, Ito M, Horie M. Biphasic P wave in lead II is a novel electrophysiologic marker for atrial fibrillation. Poster Session (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Kawamura M, Nagaoka I, Kenichi, Nishio Y, Itoh H, Kimura H, Miyamoto A, Mizusawa Y, Jito Y, Ishida K, Ito M, Makiyama T, Ohno S, Sumitomo N, Oyama K, Horie M. Mutations of the cardiac ryanodine Recepter (RyR2) gene in catecholaminergic polymorphic ventricular tachycardia. (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Ozawa T, Ito M, Itoh H, Nakazawa Y, Sugimoto Y, Yao T, Miyamoto A, Ashihara T, Horie M. Site-specific arrhythmogenesis in structurally normal heart of non-brugada patients with ventricular arrhythmias originating from ventricular outflow tract. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

Watanabe H, Nishizaki H, Kamakura S, Horie M, Hiraoka M. Recent advancement of treatment in catecholaminergic polymorphic ventricular tachycardia. Mini-Symposium(APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Li P, Ninomiya H, Kurata Y, Kato M, Miake J, Yamamoto Y, Igawa O, Nakai A, Higaki K, Toyoda F, Wu J, Horie M, Matsuura H, Yoshida A, Shirayoshi Y, Hiraoka M, Hisatome I. Reciprocal control of hERG stability by hsp70 and hsc70 with implication for restoration of LQT2 mutant stability. JSE Academic Award Competition (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福 岡)

 Ohno S, Zankov DP, Ding WG, Itoh H, Makiyama T, Doi T, Shizuta S, Hattori T, Miyamoto A, Naiki N, Matsuura H, Horie M. KCNE5 variants are novel modulators of brugada syndrome and idiopathic ventricular fibrillation. Young Investigator Award Competition (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Horie M, Ohno S, Wu J, Zankov DP, Toyoda F, Ding WG, Matsuura H. Mutations of KCNE gene family in inherited arrhythmia syndromes. Special Symposium (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Horie M, Itoh H, Shimizu W, Hayashi K, Ohno S, Makiyama T, Yamagishi M, Kamakura S. Long QT syndromes are heterogeneous disease entities presenting not only QT prolongation but multiple phenotypes - cases with compound heterozygous mutations. JHRS-JSE Joint Symposium (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)

 Horie M. Renin-Angiotensin-Aldosterone system and atrial fibrillation. Evening Seminar 1 (APHRS2011 & 26th JHRS 28th JSE 合同学会 2011.09.18-22 福岡)  Watanabe H, Nogami A, Ohkubo K, Makiyama T, Hayashi, Shimada T, Nagao S,

Yagihara N, Takehara N, Kawamura Y, Sato A, Okamura K, Hosaka Y, Sato M, Fukae S, Chinushi M, Oda H, Okabe M, Maemura K, Horie M, Watanabe I, Aizawa Y, Makita N. Clinical, electrocardiographic, and genetic characteristics of patients with idiopathic ventricular fibrillation associated with early repolarization. AHA Scientific Sessions 2011．(2011.11.12-16 Orlando, Florida, U.S.A.)

 Ohno S, Miyamoto A, T Makiyama, Itoh H, Horie M. Clinical differences between KCNH2 and SCN5A mutation carriers with Brugada syndrome and Brugada-like ECG patients in Japan. AHA Scientific Sessions 2011 ． (2011.11.12-16 Orlando, Florida, U.S.A.)

 Horie M: Short QT and Early Repolarization Syndromes. ICPES 2011 (2011.12.11-14 Ahens, Greece)

 Horie M: Basic characteristics of Brugada syndrome in Japan. ICPES 2011 (2011.12.11-14 Athens, Greece)

 Ohno S, Nishio Y, Nagaoka I, Miyamoto A, Kimura H, Itoh H, Makiyama T, Horie M: Clinical and genetic characterization of Japanese patients with arrhythmogenic right ventricular cardiomyopathy. ICPES 2011 (2011.12.11-14 Athens, Greece)

【２０１０】

 Ashihara T, Haraguchi R, Nakazawa K, Namba T, Ikeda T, Nakazawa Y, Itoh H, Sugimoto Y, Ito M, Horie M: Roles of fibroblasts in the mechanism of complex fractionated atrial electrograms during chronic atrial fibrillation. Heart Rhythm Society Meeting 2010 (2010.05.11-15, Denver, U.S.A.)

 Turker I, Chang PC, Li H, Kim JJ, Brugada R, Brugada P, Brugada J, Makiyama T, Ueyama T, Shimizu W, Shimizu A, Horie M, Ackerman MJ., Ai T, Vatta M : A telethonin mutation R154C attenuates hNav1.5 in Brugada syndrome. Heart Rhythm Society Meeting 2010 (2011.05.11-15 Denver, U.S.A )  Miyamoto A, Hayashi H, Ishida K, Yoshino T, Sugimoto Y, Ito M, Horie M: P

pulmonale and atrial fibrillation. ISHR2010 (2010.05.13-16, Kyoto)

 Matsumoto T, Nakae I, Hayashi H, Takashima H, Horie M: Impact of oxidized low-density lipoprotein on coronary microvascular endothelial function. ISHR2010 (2010.05.13-16, Kyoto)

 Yamaji M, Takayoshi Tsutamoto T, Kawahara C, Nishiyama K, Yamamoto T, Fujii M, Horie M: Effect of eplerenone versus spironolactone on cortisol and hemoglobin A1c levels in patients with chronic heart failure. ISHR2010 (2010.05.13-16, Kyoto)

 Fujii M, Tsutamoto T, Kawahara C, Nishiyama K, Yamaji M, Yamamoto T, Horie M: Prognostic role of highly sensitive cardiac troponin I in patients with systolic heart failure. ISHR2010 (2010.05.13-16, Kyoto)

Wada A, Matsumoto A, Ohnishi M, Takayama T, Tsutamoto T, Horie M: Chymase inhibition suppresses excessive oxidative stress through NADPH oxidase and improves cardiac dysfunction in heart failure. ISHR2010 (2010.05.13-16, Kyoto)

 Yoshino T, Hayashi H, Nakae I, Miyamoto A, Ishida K, Matsumoto T, Horie M: Adenosine attenuates the appearance of myocardial ischemia-induced J wave.

ISHR2010 (2010.05.13-16, Kyoto)

Hayashi H, Miyamoto A, Ishida K, Yoshino T, Sugimoto Y, Ito M, Horie M: J wave and intrathoracic tumor. ISHR2010 (2010.05.13-16, Kyoto)

 Itoh H, Shimizu W, Hayashi K, Yamagata K, Sakaguchi T, Makiyama T, Miyamoto Y, Yamagishi Y, Kamakura S, Horie M; Long QT syndrome with compound mutation is associated with a severer phenotype: a Japanese multicenter study. ESC Congress 2010 (2010.08.27- 09.01, Stockholm, Sweden) Horie M: Electrical Cardiomyopathy: Ion Channel Diseases. CJCF2010 (2010.10.15-16 Beijing, China)

 Nakazawa Y, Ashihara T, Miyamoto A, Ozawa T, Itoh H, Sugimoto Y, Ito M, Horie M: Influence of pulmonary vein isolation on heart rate : A clinical study using event-ECG monitors. APHRS2010/APAFS2010 (2010.10.28-30, Jeju Island, Korea)

 Ashihara T, Haraguchi R, Nakazawa K, Namba T, Ikeda T, Nakazawa Y, Ozawa T, Itoh H, Ito M, Horie M: Roles of fibroblasts in the mechanisms of complex fractionated atrial electrograms and catheter ablation during chronic atrial fibrillation.APHRS2010/APAFS2010 (2010.10.28-30, Jeju Island, Korea)

 Horie M: Genetic Background of Japanese Patients with Long QT Syndrome. APHRS2010/APAFS2010 (2010.10.28-30, Jeju Island, Korea)

 Itoh H, Oka Y, Ding WG, Sakaguchi T, Kimura H, Mizusawa Y, Miyamoto A, Wu J, Ohno S, Makiyama T, Ito M, Matsuura H, Horie M: Latent genetic backgrounds and molecular pathogenesis inacquired long QT syndrome with distinct arrhythmic triggers. AHA Scientific Sessions 2010 ． (2010.11.14-17 Chicago Illinois U.S.A.)

 Kimura H, Itoh H, Mizusawa Y, Miyamoto A, Oka Y, Kawamura M, Nishio Y, Sakaguchi T, Makiyama T, Ito M, Horie M: Carvedilol, an α 1- and Non-selective β-adrenoceptor Blocker, for Prevention of Cardiac Events in Patients with Type 2 Long QT Syndrome. AHA Scientific Sessions 2010． (2010.11.14-17 Chicago Illinois U.S.A.)

【２００９】

 Ohno S, Tsuji K, Makiyama T, Nishio Y, Akao M, Kita T , Horie M：Multiple mechanisms underlie long QT syndrome by the change of amino acid R259 in the

intracellular S4-S5 linker of KCNQ1．Cardiorhythm2009．（2009.2.20-22，Hong

Kong）

alpha(1A)-adrenoceptors in mammalian cell line ． Biophysical Society 53rd Annual Meeting. （Boston, U.S.A. 2.28 -3.4, 2009）

 Ito M：Validation of AF Ablations Efficiency. The 17th asian pacific congress of cardiology. (2009.5.20-23, Kyoto).

 Nishiyama K, Tsutamoto T, Yamaji M, Kawahara C, Fujii M, Yamamoto T, Horie M：Comparison of BNP and Nt-proBNP based on the prognostic value for stable outpatients with nonischemic chronic heart failure. The 17th asian pacific congress of cardiology. (2009.5.20-23, Kyoto).

 Yamaji M, Tsutamoto T, Kawahara C, Nishiyama K, Yamamoto T, Fujii M, Horie M：Serum cortisol as a cardiac event predictor of patients with chronic heart failure - Comparison with aldosterone and ACTH. The 17th asian pacific congress of cardiology. (2009.5.20-23, Kyoto).

 Kawahara C, Tsutamoto T, Yamaji M, Nishiyama K, Yamamoto T, Fujii M, Horie M：Relationship between renal function and serum cardiac troponin T in patients with chronic heart failure. The 17th asian pacific congress of cardiology. (2009.5.20-23, Kyoto).

 Horie M ： Overlap syndromes in inherited arrhythmia disorders. ISHNE 2009(2009.6.4-6 横浜).

 Ito M：Evaluation of atrial fibrillation recurrence after PV isolation; Impact of event ECG recorder. ISHNE 2009(2009.6.4-6 横浜).

 Hayashi H：Early repolarization in a hospital-based population: The prevalence and QT interval in relation to age. ISHNE 2009(2009.6.4-6 横浜).

 Ashihara T：Steep restitution slope is not an essential factor for microvolt-level T-wave alternans:Insights from computer simulations. ISHNE 2009(2009.6.4-6 横浜).

 Yao T：At-Home AED: An alternative strategy for patients with sudden cardiac death and the risk of ICD implantation. ISHNE 2009(2009.6.4-6 横浜).

 Ishida K：Prognostic value of early repolarization in short QT syndrome. ISHNE 2009(2009.6.4-6 横浜).

 Matsumoto T, Nakae I, Yamane T, Takashima H, Horie M： Inhibition of Angiotensin-Converting Enzyme Augments Coronary Tissue Plasminogen Activator Release in hypertensive women. European Society of Cardiology Congress 2009.(2009.8.29-9.2Barcelona,Spain).

 Horie M. Structure-function relationships of K channels. 2nd Asia pacific heart rhythm society science session(APHRS2009). (2009.10.22-25,Beijin,China).  Nishiyama K，Tsutamoto T，Kawahara C，Yamaji M，Tanaka T，Yamamoto T，

Fujii M ， Horie M ． Long-term Effect of Efonidipine Therapy on Plasma Aldosterone and Left Ventricular Mass Index in Patients with Essential Hypertension. AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

 Matsumoto T, Wada A, Ohnishi M, Takayama T, Dohke T, Yamamoto T, M Fujii, Tsutamoto T, Horie M :Cardiac Mast Cell Stabilization Prevents the Progression of Cardiac Remodeling

AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

 Yamagata K, Horie M, Ogawa S, Aizawa Y, Kusano K F, Ohe T, Yamagishi M, Makita N, Tanaka T, Makiyama T, Akao M, Hagiwara N, Kishi Y, Yamada Y, Okamura H, Noda T, Satomi K, Suyama K, Aihara N, Miyamoto Y, Kamakura S, Shimizu W:Clinical Phenotype and Prognosis of Probands With Brugada Syndrome in Relation to SCN5A Mutation. - Japanese Brugada Syndrome Multicenter Registry. AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

 Ohno S, Zankov DP, Ding W-G, Makiyama T, Hattori T, Doi T, Shizuta S, Kimura T, Matsuura H, Horie M：Novel KCNE5 Mutations Are Associated With Brugada Syndrome and Idiopathic Ventricular Fibrillation. AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

 Watanabe H, Makiyama T, Prince J K, Seto S, Okamura S, Oda H, Ito H, Horie M, Aizawa Y, Shimizu W:Association of Early Repolarization With Arrhythmic Events in Short QT Syndrome. AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

 Hattori T, Makiyama T, Akao M, Ehara E, Ohno S, Nishio Y, Itoh H, Yokode M, Kimura T, Horie M: A Novel Gain-of-function KCNJ2 Mutation Associated With Short QT Syndrome Impairs Inward Rectification of Kir 2.1 Currents. AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

 Tsutamoto T, Nishiyama K, Yamaji M, Kawahara C, Fujii M, Hayashi M, Horie M: Effect of Eplerenone Versus Spironolactone on Adiponectin and Hemoglobin A1c Levels in Patients With Chronic Heart Failure. AHA Scientific Sessions 2009．(2009.11.14-18 Orlando, Florida, U.S.A.)

【２００８】

 Ozeki Y，Fujii K，Kurimoto N，Tsuji K，Yamada N，Okawa M，Aoki T， Takahashi J，Ishida N，Narita M，Saito O，Horie M，Kunugi H．RISK FACTORS OF QTC INTERVAL PROLONGATION IN 1000 PATIENTS WITH SCHIZOPHRENIA．

14th Biennial winter workshop on schizophrenia and bipolar disorders （2008/2/3-7，Switzerland）

 松本鉄也．心筋梗塞二次予防ガイドラインからみた硝酸薬の使い方．Roundtable Discussion．（2008.3.30 福岡）

 Horie M．A KCNE1 polymorphism,D85N,is a disease-causing gene variant in congenital long QT syndrome．ESC Congress 2008．(2008/8/31-9/3，Munchen， Germany)

 Tsutamoto T．Nicorandil:newly approved medication in pts with acute heart failure in Japan,its mechanism of action and characteristics．Round table discussion focused on the management of acute heart failure．（2008/8/31， Munchen,Germany）

 Matsumoto T，Yamane T，Eguchi Y，Takashima H，Urade Y，Horie M． Lipocalin-type Prostaglandin D Synthase is Associated with Coronary Vasomotion in Response to Acetylcholine in Patients with Coronary Vasospastic Angina．ESC Congress 2008．（2008/8/31-9/3，Munchen，Germany）

 Horie M．Plakophili-2 mutations are common in Japanese arrhythmogenic right ventricular dysplasia/cardiomyopathy ． 2008 Tokyo-Taipei-Seoul Arrhythmia Joint Conference．（2008.10.4 Seoul，Korea）．

 Bayer JD，Narayan SM，Ashihara T，Lalani G，Plank G，Trayanova NA．Reduced calcium uptake explains human action potential phase II and T-wave alternans: A modeling and clinical study ． Heart Rhythm 2008 Scientific Sessions ． （2008.5.14-17 San Francisco，U.S.A.）

 Tsuji K，Akao M，Ishii TM，Ashihara T，Makiyama T，Ohno S，Toyoda F， Nishio Y，Sakaguchi T，Matsuura H，Horie M．Identification and functional characterization of a novel intronic splicing mutation in KCNQ1 associated with long QT syndrome．American Heart Association (AHA) 80th Scientific Sessions． （2008.11.8-12，New Orleans,U.S.A）

 Nishiyama K，Tsutamoto T，Kawahara C，Yamaji M，Tanaka T，Yamamoto T， Fujii M，Horie M．Transcardiac increase in Norepinephrine and prognosis in patients with chronic heart failure．AHA Scientific Sessions 2008．(2008.11.8-12 New Orleans,U.S.A.)

 Yao T，Jo H，Nakazawa Y，Itoh H，Ashihara T，Sugimoto Y，Ito M，Horie M． Ventricular lead of mid-septal position shows voltage reduction after ICD/CRT-D implantation. 1st Asia-Pacific Heart Rhythm Society Scientific Session （2008.11.27-29，Raffles，Singapore）

A detection rate of atrial fibrillation by symptoms decreased after pulmonary vein Isolation: A clinical study using event-ECG monitors. st Asia-Pacific Heart Rhythm Society Scientific Session（2008.11.27-29，Raffles，Singapore）

 Zankov DP，Omatsu-Kanbe M，Matsuura H，Horie M．Involvement of AT1 receptor in swelling-induced regulation of IKS current in guinea pig atrium．第 ２５回 国際心臓研究学会（ISHR）日本部会．（2008.12.5 神奈川）

【２００７】

 Horie M．The 1st International Congress of Cardiomyopathies and Heart Failure, （2007.3.10-13 Kyoto,Japan）．

 Tsutamoto T． Inflammatory biomarkers．The 1st International Congress of Cardiomyopathies and Heart Failure．（2007.3.10-13 Kyoto,Japan）．

 Itoh H, Makiyama T, Oono S, Tsuji K, Oka Y, Sakaguchi T, Nagaoka I, Nakazawa Y, Yao T, Ashihara T, Ito M, Akao M, Horie M． Variable genetic backgrounds between congenital and acquired long-QT syndromes( Oral(Japanese)). The 71st Annual Scientific Meeting of Japanese Circulation Society． (2007.3.15-17, Kobe，Japan).

 Nagaoka I, Itoh H, Sakaguchi T, Oka Y, Ashihara T, Yao T, Jo H, Nakazawa Y, Ito M, Sumitomo N, Horie M ． Mutation analysis for the human cariac ryanodine receptor gene (RyR2) in catecholaminergic polymorphic ventricular tachycardia (CPVT)(Oral(Japanease))．The 71st Annual Scientific Meeting of Japanese Circulation Society． (2007.3.15-17, Kobe，Japan)．

 Harada M, Honjo H, Yamazaki M, Nakagawa H, Ishiguro Y, Okuno Y, Ashihara T, Nakazawa K, Sakuma I, Horie M, Kamiya K, Kodama I ． Moderate hypothermia causes destabilization of rotors without wavelength shortening in favor of VT/VF self-termination(Poster). The 71st Annual Scientific Meeting of Japanese Circulation Society． (2007.3.15-17, Kobe，Japan)．

 Namba T, Ashihara T, Yao T, Nakazawa K, Ikeda T．Electrode potential is available for evaluating the local repolarization during fibrillation(Oral). The 71st Annual Scientific Meeting of Japanese Circulation Society． (2007.3.15-17, Kobe，Japan)．

 Oka Y, Makiyama T, Itoh H, Oono S, Sakaguchi T, Nagaoka I, Ashihara T, Ito M, Akao M, Horie M．Clinical characteristics for Japanese patients with genotyped long-QT syndrome(Poster). The 71st Annual Scientific Meeting of Japanese Circulation Society． (2007.3.15-17, Kobe，Japan)．

Ito M, Matsuura H, Horie M． A novel KCNH2 mutation associated with the short QT interval of Brugada syndrome．Impaired deactivation for the IKr channel(Poster). 56th Annual Scientific Session of the American College of Cardiology (ACC)． (2007.3.24-27,New Orleans,U.S.A.).

 Itoh H, Makiyama T, Ohno S, Oka Y, Sakaguchi T, Nagaoka I, Ashihara T, Ito M, Akao M, Horie M ． Variable genetic backgrounds between congenital and acquired long-QT syndromes(Oral). 56th Annual Scientific Session of the American College of Cardiology (ACC)．(2007.3.24-27,New Orleans,U.S.A.).  Namba T, Todo T, Yao T, Ashihara T, Haraguchi R, Nakazawa K, Ikeda T．

Identification of local myocardial repolarization endpoint by bipolar electrode potential mapping without determining activation time of each electrode．The 32nd Annual Conference of International Society for Computerized Electrocardiology．（2007.4.21-26 Cancun）．

 Namba T, Todo T, Yao T, Ashihara T, Haraguchi R, Nakazawa K, Ikeda T． Bipolar electrode potential available for evaluating the local myocardial repolarization(Oral). The 31st Annual Conference of International Society for Computerized Electrocardiology (ISCE)．(2007.4.21-26, Cancun,Mexico).

 Ashihara T, Yao T, Ito M, Horie M, Haraguchi R, Nakazawa K, Namba T, Ikeda T, Trayanova NA．Steep APD restitution curve is not essential for microvolt T-wave alternans(Oral) ． Insights from computer simulations. Heart Rhythm 2007 Scientific Sessions．(2007.5.9-12,Denver,U.S.A.).

 Harada M, Honjo H, Yamazaki M, Nakagawa H, Ishiguro YS, Okuno Y, Nakazawa K, Ashihara T, Horie M, Sakuma I, Kamiya K, Kodama I．Moderate hypothermia increases the chance of spiral wave collision in favor of self-termination of ventricular tachycardia/fibrillation(Poster). Heart Rhythm 2007 Scientific Sessions．(2007.5.9-12,Denver,U.S.A.)

 Namba T, Haraguchi R, Igarashi T, Owada S, Yao T, Ashihara T, Todo T, Ikeda T, Nakazawa K．Development of graphical interface modeling excitation map in the electrophysiological heart simulator(Poster) ． IEEE/ICME International

Conference on Complex Medical Engineering (CME) ．

(2007.5.23-27,Beijing,China).

 Todo T, Haraguchi R, Namba T, Yao T, Ashihara T, Higashi M, Inada H, Nakazawa K．Development of “Cardiac Arrhythmia Risk Evaluation” system based on computer simulation(Poster). IEEE/ICME International Conference on Complex Medical Engineering (CME)．(2007.5.23-27,Beijing,China)．

Cardiovascular Symposium（2007.7.27-29 Harbin,China）．

 Nagaoka I， Shimizu W，Itoh H，Ohno S，Akao M，Miyamoto Y，Kamakura S， Horie M．Bradycardia before beta-blocker therapy as an arrhythmic risk in LQT2 form of congenital long-QT syndrome．ESC Congress 2007．（2007.9.1-5 Vienna,Austria）．

 Yao T, Jo H, Nakazawa Y, Ashihara T, Itoh H, Sugimoto Y, Ito M, Horie M． Prediction and prevention of T-wave oversensing in patients with implantable cardioverter defibrillators ． 10th International Workshop on Cardiac Arrhythmias ．（2007.10.7-10Venice）．

 Nakazawa Y，Ashsihara T，Yao T，Tanaka T，Jo H，Itoh H，Yagi T，Sugimoto Y，Tsutamoto T，Ito M，Horie M．Plasma endotheline-1 level before extensive encircling pulmonary vein isolation as a predict or of atrial fibrillarion recurrences after 6 months. Venice Arrhythmias（2007.10. 8-10 Italia）．  Jie Wu．Inhibitory actions of ly294002,a PI3 kinase inhibitor,on the human kv1.5

channel．The 3rd Asia-Pacific Atrial Fibrillation Symposium．（ 2007.10.18 TAIWAN）．

 Ashihara T．Visualization of the mechanisms of atrial fibrillation:Insights from computer simulations．The 3rd Asia-Pacific Atrial Fibrillation Symposium． （2007.10.19 TAIWAN）．

 Horie M ．The same genetics for Brugada syndrome and AF ? ．The 3rd Asia-Pacific Atrial Fibrillation Symposium．（2007.10.20 TAIWAN）．

 Wada A，Matsumoto T，Ohnishi M，Takayama T，Tsutamoto T，Horie M．Chronic NADPH Oxidase Inhibition Improves Cardiac Dysfunction Through The Suppression Of Cardiac Oxidative Stress And The Renin-Angiotensin System In Heart Failure ．The American Heart Association Scientific Sessions 2007 ． （2007.11.4，U.S.A）．

 Makita N，Behr E，Shimizu W，Horie M，Crotti L，Itoh H，Miyamoto K， Kamakura S，Tsutsui H，Schwartz PJ，George AL Jr，Roden DM．Overlap Between LQT3 and Brugada Syndrome: Clinical Features in a Common Mutation and Underlying Biophysical Mechanisms ． The American Heart Association Scientific Sessions 2007．（2007.11.5，U.S.A）．

 Makiyama T，Akao M，Shizuta S，Doi T，Ohno S，Nishio Y，Kimura T，Horie M．Familial Dilated Cardiomyopathy with Conduction Disease Caused by a Lamin A/C Mutation: Efficacy of the Cardiac Resynchronization Therapy with a Defibrillator ． The American Heart Association Scientific Sessions 2007 ． （2007.11.5，U.S.A）．

 Zankov DP，Toyoda F，Omatsu-Kanbe M，Matsuura H，Horie M．Angiotensin II Type 1 Receptor Partially Mediates Stretch-Induced Potentiation of the Slow Component of Delayed Rectifier Potassium Current in Guinea Pig Atrium．The American Heart Association Scientific Sessions 2007．（2007.11.6，U.S.A）．  Sakaguchi T，Shimizu W，Ito H，Noda T，Miyamoto Y，Nagaoka I，Ashihara

T，I to M，Tsuji K，Ohno S，Makiyama T，Kamakura S，Horie M．Age-Related Triggers for Life-Threatning Arrhythmia in the Genotyped Long QT Syndrome． The American Heart Association Scientific Sessions 2007．（2007.11.6，U.S.A）．  Hayashi M，Tsutamoto T，Naiki N，Yamaji M，Ohira N，Yokohama H，Horie

M ． Hyper Transcardiac Extraction of Aldosterone Promote Ventricular Remodeling and Cardiac Mass in Patients with Primary Aldosteronism．The American Heart Association Scientific Sessions 2007．（2007.11.6，U.S.A）．  Ashihara T, Yao T, Namba T, Nakazawa Y, Jo H, Ito H, Sugimoto Y, Ito M,

Haraguchi R, Nakazawa K, Ikeda T, Horie M．Effects of amiodarone and bepridil on spiral wave reentries in human atrial model with electrical and structural remodelings．文部科学省リーディングプロジェクト「細胞・生体機能シミュレー

ションプロジェクト」京都大学拠点第4 回国際シンポジウム．（2007.11.12-13Kyoto）．

 Horie M．Diagnostic criteria for the long QT syndrome．World Congress on Cardiac Pacing and Electrophysiology（2007.12.2-6 Rome,Italy）．

 Haraguchi R, Nakazawa K, Ashihara T, Namba T, Todo T, Naito H, Higashi M, Shimizu W, Suzuki S, Murakami S, Kurachi Y．Scroll wave dynamics in a three-dimensional cardiac tissue model: Roles of transmural dispersion of

repolarization. The 2nd MEI International Symposium．（2007.12.7-9 Osaka）．

 Ashihara T ． Simulation studies of excitation conduction and cardiac arrhythmias．The 2nd MEI International Symposium．（2007.12.7-9 Osaka）．  Ijiri T, Takayama K, Igarashi T, Ashihara T, Namba T, Yamaguchi T, Shimada T,

Haraguchi R, Nakazawa K．The use of L-system for modeling Purkinje fibers． The 2nd MEI International Symposium．（2007.12.7-9 Osaka）．

【２００６】

 Ashihara T, Yao T, Ito M, Horie M, Haraguchi R, Nakazawa K, Trayanova NA. Superiority of biphasic waveforms in a bidomain model study. Commission investigating the DFT management and DAVID study (2006.02.17 Osaka).  Yamazaki M, Honjo H, Ashihara T, Harada M, Sakuma I, Nakazawa K, Horie M,

Trayanova N, Kamika K, Kodama I. Regional cooling facilitates termination of spiral wave reentry through unpinning of rotors in 2-dimenshonal rabbit

ventricular myocardium. Heart Rhythm 2006 Scientific Sessions. (2006.05.17-20 Boston).

 Kuo SR, Niwa N, Ashihara T, Nikolski V, Fedorov V, Efimov I, Trayanova N. Role of electroporation in initiation of spontaneous ectopic postshock activations. Heart Rhythm 2006 Scientific Sessions (2006.05.17-20 Boston).

 Arafune T, Ashihara T, Nakazawa K, Trayanova NA, Yamazaki M, Honjo H, Kamiya K, Kodama I, Sakuma I. Analysis of shock induced virtual electrode polarization in various hypothermia and capture mechanisms. Heart Rhythm 2006 Scientific Sessions (2006.05.17-20 Boston).

 Lu J, Nishi T, Ashihara T, Schnider N, Amano A, Matsuda T, Kotera H. The influence of activation time on the contraction force of myocardial tissue: A simulation study. The 28th IEEE Engineering in Medicine and Biology Society Annual International Conference. (2006.08.30-09.03 New York).

 Horie M, Itoh H, Sakaguchi T, Yamamoto S, Nagaoka I, Zankov DP, Ashihara T, Ito M, Yoshida H, Tsuji K, Ohno S, Makiyama T, Akao M,Kita T. Long QT syndrome: an ion channelopathy in cardiovasccular medicine. The 11th La Jolla-Capri-Yamaguchi -Seoul Research Conference. (2006.10.06-08 Yamaguchi).  Matsumoto T, Taruani Y, Yamane T, Takashima H, Matsuo S, Horie M. Regulation of blood pressure improves both coronary endothelial function and aortic stiffness in hypertensive patients. International Society of Hypertension 21st Biennial Meeting (2006.10.15-19 Fukuoka).

 Matsumoto T, Fujita M, Tarutani Y, Yamane T, Takashima H, Matsuo S, Nakae I, Horie M. Whole-body, periodic acceleration enhances endothelium-dependent flow-mediated vasodilation of the brachial artery. International Society of Hypertension 21st Biennial Meeting. (2006.10.15-19 Fukuoka).

 Tamaki S, Nakamura Y, Yoshino T, Matsumoto Y, Tarutani Y, Okabayashi T, Kawashima T, Horie M. The association between morning hypertension and metabolic syndrome in hypertensive patients. International Society of Hypertension 21st Biennial Meeting (2006.10.15-19 Fukuoka).

 Tamaki S, Nakamura Y, Tabaa Y, Okamura T, Kita Y, Kadowaki T, Tsujita Y, Horie M, Miki T, Ueshima H. Relation ship between the metabolic syndrome and Trp64Arg polymorphism of the β3 adrenergic receptor gene in a general sample (The Shigaraki Study). International Society of Hypertension 21st Biennial Meeting (2006.10.15-19 Fukuoka).

 Tamaki S, Kawashima T, Yashino T, Matsumoto Y, Taruani Y, Okabayashi T, Horie M. Change of medication to Candesartan from Valasartan is effective for

patients with morning hypertension (ATOM-Convert study). International Society of Hypertension 21st Biennial Meeting (2006.10.15-19 Fukuoka).

 Tanaka T, Tsutamoto T, Sakai H, Fujii M, Yamamoto T. Efonidipine decreases aldosterone compared with amlodipine in patients with hypertension. International Society of Hypertension 21st Biennial Meeting (2006.10.15-19 Fukuoka).

 Tsutamoto T, Hayashi M, Sakai H, Tanaka T, Ishikawa C, Fujii M, Horie M. The role of aldosterone on left ventricular remodeling in patients with acute myocardial infarction. Investigator-Initiated Symposia : Chymase Comprehending Tissue Renin-Angiotensin Generating System (2006.10.20-21 Takarazuka).

 Tanaka T, Tsutamoto T, Sakai H, Fujii M, Yamamoto T. Efonidipine decreases aldosterone compared with amlodipine in patients with hypertension.The 21st Scientific Session, International Society of Hypertension : Investigator-Initiated Symposia : Chymase Comprehending Tissue Renin-Angiotensin Generating System (2006.10.20-21 Takarazuka).

 Sakai H, Tsutamoto T, Tanaka T, Fujii M, Horie M. Direct comparison of brain natriuretic peptide (BNP) and N-terminal Pro-BNP secretion and extent of coronary artery stenosis in patients with stable coronary artery disease. The 2th China-Japan Cardiovascular Forum (2006.11.04 Beijing).

 Tsutamoto T, Wada A, Sakai H, Ishikawa C, Tanaka T, Hayashi M, Fujii M, Yamamoto T, Dohke T, Ohnishi M, Kinoshita M, Horie M. Relationship between renal function and plasma brain natriuretic peptide in patients with heart failure. The 2th China-Japan Cardiovascular Forum (2006.11.04 Beijing).

 Tanaka T, Tsutamoto T, Sakai H, Fujii M, Yamamoto T. Effect of T-Type calcium channel blocker versus L-Type calcium channel blocker on aldosterone in patients with hypertension. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Suyama T, Taniguchi R, Haruna Y, Shizuta S, Tamura T, TOma M, Furukawa Y, Ehara N, Horie M, Asai T, Araki M, Doyama K, Fujino Y, Imai Y, Teramukai S, Kita T, Kimura T. Impact of complete revascularization on long-term outcome after percutaneous coronary intervention in the bare metal stent era : from the coronary revascularization demonstrating outcomes in Kyoto (CREDO-Kyoto). 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).  Zhang L, Benson W, Riera A, Paulo S, Ptacek L, Tristani-Firouzi M, Ackerman

abnormalities in type 1 Andersen-Tawil syndrome: The enlarged U wave, prolonged QU interval and left ventricular arrhythmias. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Matsumoto T, Yamane T, Takashima H, Horie M. Chronic smoking impairs endogenous coronary fibrinolytic function in women with angiographically normal coronary arteries. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Matsumoto T, Yamane T, Takashima H, Horie M. Angiotensin II receptor blockade improves endogenous coronary fibrinolytic function in patients with coronary artery disease. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Wada A, Matsumoto T, Takayama T, Dohke T, Ohnishi M, Tsutamoto T, Horie M. Chronic chymase inhibition improves cardiac dysfunction through the suppression of excessive oxidative stress in heart failure. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Matsumoto T, Wada A, Tsutamoto T, Ohnishi M, Fujii M, Yamamoto T, Takayama T, Dohke T, Horie M. Chymase inhibitor improves renal dysfunction under long-term angiotensin-converting enzyme inhibition in heart failure. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).  Tsuji K, Akao M, Ishii T, Ohno S, Makiyama T, Doi T, Haruna Y, Yoshida

H,Nakashima T, Kita T, HorieM. Mechanistic basis for the pathogenesis of long QT syndrome caused by a splicing mutation in KCNQ1 gene. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Hata N, Seino Y, Tsutamoto T, Suzuki H, Hiramitsu S, Yoshikawa T, Yokoyama Y, Tanaka K, Mizuno K, Nejima J, Kinoshita M. PROTECT. Effects of carperitide (hANP) treatment on long-term Pprognosis in patients with acute decompensated heart failure. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Schwartz PJ, Spazzolini C, Crotti L, Vicentini A, Horie M, Moss AJ, Shimizu W, Schulze-Bahr E, Munster U, Munster, Wilde AA. The Common LQT1 Mutation KCNQ1/A341V Predicts High Risk of Cardiac Events in Different Ethnic Backgrounds. 79th American Heart Association Scientific Sessions (2006.11.12-15 Chicago).

 Horie M, Dimitar PZ, Zhang C, Yasuno S, Kuwahara K, Omatsu-Kanbe M, Isono T, Toyoda F, Ding WG, Makiyama T, Matsuura H. Angiotensin (AT1) receptor and atrial fibrillation. The 2nd Asia-Pacific Atrial Fibrillation Symposium

(2006.11.23-25 Tokyo).

 Yao T, Nakazawa Y, Ashihara T, Jo H, Itoh H, Yagi T, Sugimoto Y, Ito M, Horie M. Effectiveness of horizontal linear ablation in left atrial posterior wall to terminate the refractory atrial fibrillation. The 2nd Asia-Pacific Atrial Fibrillation Symposium (2006.11.23-25 Tokyo).

 Ashihara T, Nakazawa Y, Yao T, Jo H, Itoh H, Yagi T, Sugimoto Y, Ito M, Horie M. Usefulness of portable electocardiograph in detecting a recurrence of atrial fibrillation after catheter ablation. The 2nd Asia-Pacific Atrial Fibrillation Symposium (2006.11.23-25 Tokyo).

 Nakazawa Y, Ashihara T, Yao T, Tanaka T, Sakai H, Jo H, Itoh H, Yagi T, Sugimoto Y, Tsutamoto T, Ito M. Recurrence of atrial fibrillation after catheter ablation can be predicted by neurohormonal factors and oxidative stress-related markers in early phase. The 2nd Asia-Pacific Atrial Fibrillation Symposium (2006.11.23-25 Tokyo).

 Namba T, Ashihara T, Yao T, Todo T, Haraguchi R, Nakazawa K, Ikeda T, Ohe T. Availability of electrode mapping for evaluating repolarization dynamics over myocardium during atrial fibrillation.The 2nd Asia-Pacific Atrial Fibrillation Symposium (2006.11.23-25 Tokyo).

【２００５】

 Sakai H, Tsutamoto T, Tsutsui T, Ishikawa C, Horie M. Serum level of uric acid, partly secreted from the failinf heart, is a prognostic marker in japanese patients with condestive heart failure. 54th Annual Scientific Session, American College of Cardiology (2005.03.06-09 Florida).

 Tsutamoto T, Wada A, Fujii M, Sakai H, Ohno K, Ishikawa C, Yamamoto T, Takayama T, Dohke T, Horie M. Relationship between renal function and plasma level of BNP and N-terminal proBNP in patients with condestive heart failure. 54th Annual Scientific Session, American College of Cardiology (2005.03.06-09 Florida).

 Hori K, Nishi T, Lu J, Shimayoshi T, Ashihara T, Amano A, Matsuda T. Development of distributed biodynamics simulator on DynaBioS architecture. Satellite Symposium of International Union of Physiological Sciences (IUPS).,35th International Congress of Physiological Sciences : Poster (2005.03.28-30, San Diego).

 Honjo H, Yamazaki M, Ashihara T, Sakuma I, Nakazawa K, Trayanova NA, Kamiya K, Kodama I. Control of functional reentry by regional cooling in an

epicardial layer of rabbit ventricular myocardium. Heart Rhythm 2005 Scientific Sessions : Poster (2005.05.04-07, New Orleans).

 Ashihara T, Trayanova NA, Nakazawa K, Yamazaki M, Honjo H, Sakuma I, Kamiya K, Kodama I. Spiral wave control by regional cooling in a bidomain model. Heart Rhythm 2005 Scientific Sessions : Poster (2005.05.04-07, New Orleans).

 Ashihara T, Trayanova NA, Yao T, Ozawa T, Ito M, Horie M. Mechanisms underlying Andersen syndrome in a human ventricular model. Heart Rhythm 2005 Scientific Sessions : Poster (2005.05.04-07, New Orleans).

 Matsuo S, Matsumoto T, Nakae I, Masuda D, Horie M. Impact of endothelial dysfunction on left ventricular remodeling after primary coronary angioplasty for acute myocardial infarction: quantitative ECG-gated SPECT. 7th International Conference of Nuclear Cardiology (2005.05.08-11, Lisbon).

 Haraguchi R, Igarashi T, Owada S, Yao T, Namba T, Ashihara T, Ikeda T, Nakazawa K. Electrophysiological heart simulator equipped with sketchy 3-D modeling. The 1st International Conference on Complex Medical Engineering (CME). : Poster (2005.05.15-18, Takamatsu).

 Toda H, Ding WG, Yasuda Y, Toyoda F, Horie M, Matsuura H. PK Ce isoform  preferentially mediates the α1-adrenergic potentiation of IKs in guineapig  cardiac myocytes. The Proceedings of the 82nd Annual Meeting (2005.05.18-20

Sendai).

 Namba T, Ikeda T, Yao T, Ashihara T, Haraguchi R, Nakazawa K, Ohe T. Amiodarone organizes multiple wavelets into a simple spiral reentry. The 27th Annual Congress of the European Society of Cardiology (ESC). : Poster (2005.09.03-07 Stockholm).

 Ohno S, Yoshida K, Tsuji K, Makiyama T, Takenaka K, Akao H, Kita T, Horie M. Positive arginine residue (R259). in S4-S5 linker affects activation properties of KCNQ1 potassium channne. ESC Congres (2005.09.03-07 Stockholm).

 Ashihara T. Myocardial cooling could control ventricular fibrillation anddecrease defibrillation threshold. Cardiac Arrhythmia and DefibrillationWorkshop-CADP Group Meeting (2005.10.10 Nagoya).

 Ashihara T. Fibrillation control by myocardial cooling in a bidomain model. Integrated Biology Workshop in University of Oxford(2005.09.29-30 Oxford).  Hayashi M, Tsutamoto T, Kimura H, Taniguchi A, Nozato Y, Takayama T,

Morigami N, Horie M. Angiotensine receptir bocker combined with spironolactone has more beneficial effect on cardiac protection than thiazide in

patients with essential hypertension. 78th American Heart Association Scientific Sessions(2005.11.13-16 Dallas).

 Hayashi M, Tsutamoto T, Kimura H, Taniguchi A, Nozato Y, Takayama T, Morigami N, Horie M. Relationship between transcardiac gradient of endothelin-1 and the desases activity of coronary spasmus in patients with coronary spastic angina 78th American Heart Association Scientific Sessions(2005.11.13-16 Dallas).

 Ishikawa C, Tsutamoto T, Sakai H, Tanaka T, Dohke T, Fujii M, Wada A, Horie M. Plasma active renin concentration as an independent prognostic predictor in patients with chronic heart failure. 78th American Heart Association Scientific Sessions(2005.11.13-16 Dallas).

 Wada A, Takayama T, Tsutamoto T, Dohke T, Fujii M, Yamamoto T, Matsumoto Horie M. Chronic NADPH oxidase inhibition improves cardiac dysfunction through the supression od oxidative stress in faling heart. 78th American Heart Association Scientific Sessions(2005.11.13-16 Dallas).

【２００４】

 Ikeda T, Kawase A, Yusu S, Nakazawa K, Ashihara T, Namba T, Yao T, Yoshino H. Effects of antiarrhythmic drugs on electrophysiological action and wavefront dynamics during atrial fibrillation. The 68th Annual Scientific Meeting of Japanese Circulation Society (2004.03.27-29 Tokyo).

 Ozawa T, Ito M, Tamaki S, Yao T, Ashihara T, Kita Y, Ueshima H, Nakamura Y, Horie M. Ventricular repolarization abnormality in Japanese carriers of G643S single nucleotide polymorphism of KCNQ1 gene. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Kobori A, Sarai N, Matsuoka S, Takano M, Noma A, Kita T, Horie M. A simulation study for risk estimation of arrhythmogenesis additional gene variants affect the phenotype of long QT syndrome. 細胞・生体機能シュミレーシ ョンプロジェクト (2004.02.27-28 Kyoto）.

 Ohno K, Tsutamoto T, Ishikawa C, Sakai H, Tsutsui T, Hayashi M, Wada A, Horie M. Relationship between the transcardiac increase of plasma heart-type fatty acid-binding protein and left ventricular remodeling in patients with dilated cardiomyopaty. ACC (2004.03.07-10 New Orleans).

 Matsuo S, Matsumoto T, Nakae I, Masuda D, Koh T, Horie M. Noninvasive evaluation of coronary artery plaque with ECG-gated multislice computed tomography. ACC (2004.03.07-10 New Orleans).

 Tsutamoto T, Ishikawa C, Ohno K, Sakai H, Wada A, Ohnishi M, Horie M. Torasemide inhibits transcardiac extraction of aldosteron in patients with congestive heart failure. ACC (2004.03.07-10 New Orleans).

 Namba T,Yao T, Ikeda T, Nakazawa K, Nakagawa H, Yamasaki M, Honjo H, Kodama I, Arafune T, Mishima A, Sakuma I, Ohe T: Coronary artery affects the wave propagation in a thin ventricular myocardium study by the optical mapping and computer graphics techniques. The 68th Annual Scientific Meeting of Japanese Circulation Society (2004.03.29 Tokyo).

 Ashihara T, Trayanova N. Mechanism of shock-induced arrhythmogenesis: role of tissue discontinuity and electroporation in the initiation of focal repetitive postshock activations. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Ashihara T, Trayanova N. Shock-induced changes in transmembrane potential: what is the asymmetry due to insights from bidomain simulations. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Kobori A, Inoue T, Hosaka Y, Washizuka T, Murakami T, Yamanouchi H, Ushinohama H,Nakamura Y, Ai T, Aizawa Y, Kita T, Horie M. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Kubota T, Tsuchiya K, Hirano T, Yamaguchi K, Nishigaki K, Minatoguchi S, Fujiwara H, Gouya M, Iesaka Y, Takahashi A. A case of tachycardia-induced cardiomyopathy caused by ectopic atrial tachycardia originating from the right atrial appendage. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Namba T, Yao T, Nakagawa H, Yamasaki M, Ikeda T, Nakazawa K, Honjo H, Kamiya K, Kodama I, Arafune T, Mishima A, Sakuma I, Ohe T. Unexcited core of spiral wave reentry has a small but obviously depolarized potential-study by optical mapping and computer graphics-. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Toda H, Ding W, Toyoda F, Yasuda Y, Ito M, Horie M, Matsuura H. Potentiation of IKS potassium current in guinea-pig ventricular myocytes by sphingosine-1-phosphate. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Toyoda F, Zankov D, Ding W, Matsuura H. Differential effects of mefenamic acid on cardiac IKS and KCNQ1/KCNE1 channeles. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

Heterogeneous distribution of the muscarinic K+ channels in guinea-pig atria. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).  Zankov D, Toyoda F, Ding W, Matsuura H, Horie M. Stimulatory action of

angiotensin II on IKS potassium current in guinea-pig atrial cells. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Zankov D, Toyoda F, Ding W, Matsuura H, Horie M. Acute Inhibition on IKS by amiodarone in guinea-pig ventricular myocytes. The 31st International Congress On Electrocardiology (2004.06.27-07.01 Kyoto).

 Matsumoto T, Wada A, Ohnishi M, Fujii M, Yamamoto T, Takayama T, Dohke T, Tsutamoto T, Horie M. Chronic chymase inhibition prevented cardiac fibrosis and improved diastolic dysfunction in the progression of heart failure. A Symposium of DEFINING THE TARGETS FOR TREATMENT OF HEART FAILURE at the XVIII World Congress of the International Society for Heart Research and the 52nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (2004.08.09 Brisbane).

 Hayashi M, Tsutamoto T, Kimura H, Miyamoto A, Taniguchi A, Nozato Y, Morigami N, Horie M. Aldosterone blocker spironolactone prevents postinfarction left ventricular late remodeling in patients with first anterior acute myocardial infarction. American Heart Association (2004.11.07 New Orleans).

 Matsuo S. Non-invasive evaluation of coronary artery plaque with ECG-gated multislice computed tomography. Takeda Fireside - Conference for young investigators～AHA Scientific Sessions 2004～ (2004.11.07 New Orleans).  Takayama T, Wada A, Fujii M, Yamamoto T, Dohke T, Matsumoto T, Tsutamoto T,

Horie M. Myocardial NADPH oxidase is a major source of reactive oxgen species in heart failure. American Heart Association (2004.11.07-10 New Orleans).  Matsuo S, Matsumoto T, Nakae I Masuda D, Takashima H, Koh T, Tarutani Y,

Horie M. Impaired sympathetic nerve function may play an important role in enhanced coronary vasoconstriction in patients with hypertrophic cardiomyopathy. American Heart Association (2004.11.07-10 New Orleans).

 Horie M. Genetic basis for sudden cardiac death: A lesson from inherited fatal arrhythmias. ISHR, The 21st Annual Meeting of the Japanese Section (2004.11.23-25 Yamanashi).

 Ashihara T, Horie M. Mechanisms of predominant U wave and bigeminal premature ventricular contractions in a computer model of Andersen-Tawil syndrome. 2nd Kyoto University International Symposium of Leading Project

for Biosimulation: The heart simulation: From cell metabolism to clinical application (2004.11.26-27 Kyoto).

 Nakazawa K, Haraguchi R, Namba T, Yao T, Ikeda T, Igarashi T, Ashihara T. Semiautomatic method for reproducing realistic excitation propagation via Purkinje fibers in human ventricular model. 2nd Kyoto University International Symposium of Leading Project for Biosimulation: The heart simulation: From cell metabolism to clinical application (2004.11.26-27 Kyoto).