Distribution of CNPase-positive oligodendrocytes in the cingulate deep cortex of the cerebrum in offspring exposed to DBDE from mid-gestation to the end of lactation. (A, B) A male offspring on PNW 11 given DBDE at 0 (control) (A) or 1,000 ppm (B). Compared with the control, decrease of CNPase-positive oligodendrocytes is evident with 1,000 ppm DBDE. CNPase-immunohistochemistry.
200x magnification.
100
Table 2-1. List of genes commonly up-regulated in the microdissected cerebral white matter region after treatment with anti-thyroid agents (≥ 2-fold)
Accession number Gene title Symbol MMI PTU, 3 ppm PTU, 12 ppm
Up-regulated (428 genes)
NM_031502 amylase 2, pancreatic Amy2 46.70 64.86 102.80
AW918413 EST - 14.19 26.48 8.57
BF545930 EST - 13.86 21.20 30.60
NM_001013965 tektin 4 Tekt4 12.56 40.08 30.84
BF548234 EST - 8.82 14.30 19.40
NM_001106848 Ring finger protein 7 Rnf7 8.50 8.17 4.59
NM_001010970 amylase 1, salivary Amy1 8.37 11.41 17.62
XM_001060951 coiled-coil domain containing 113 Ccdc113 8.32 20.95 18.68 NM_001106595 SET and MYND domain containing 1 Smyd1 8.21 9.71 13.66
NM_144750 lysophospholipase LOC246266 7.67 6.39 14.72
AW529115 EST - 7.60 17.74 16.75
BE095613 EST - 6.95 8.56 14.54
NM_001107747 Rho GTPase activating protein 1 Arhgap1 6.28 3.98 9.55 NM_001107049 tetratricopeptide repeat domain 25 Ttc25 6.27 15.96 18.34 NM_001039035 Splicing factor, arginine/serine-rich 7 Sfrs7 6.22 5.86 6.11
BE107816 EST - 6.10 7.71 7.62
BF542399 EST - 5.65 5.50 9.98
NM_031664 solute carrier family 28 (sodium-coupled
nucleoside transporter), member 2 Slc28a2 5.49 12.30 14.35
AW251647 EST - 5.47 10.34 10.54
BF398031 EST - 5.44 3.97 6.55
BE113460 EST - 5.42 3.48 9.31
NM_001015032 UDP-N-acetyl-alpha-D-galactosamine:polyp
eptide N-acetylgalactosaminyltransferase 3 Galnt3 5.35 3.62 4.74 XM_213312 family with sequence similarity 183,
member B Fam183b 5.34 10.84 11.19
AA893195 EST - 5.33 22.57 13.10
BF399373 EST - 5.29 3.54 4.57
BF400248 EST - 5.15 6.50 7.96
NM_033021 SEC31 homolog A Sec31a 5.09 7.55 8.53
BF405546 EST - 5.09 7.05 7.92
BM385105 EST - 5.07 5.20 8.42
AI407705 EST - 5.05 7.26 10.77
NM_052803 ATPase, Cu++ transporting, alpha
polypeptide Atp7a 5.02 11.39 11.09
NM_001015027 cAMP responsive element binding
protein-like 2 Crebl2 5.02 10.61 11.53
NM_001108564 amylo-1,6-glucosidase,
4-alpha-glucanotransferase Agl 5.01 2.69 4.57
NM_012929 collagen, type II, alpha 1 Col2a1 4.90 7.40 7.29
NM_001024345 tropomyosin 2 Tpm2 4.74 7.20 9.42
AI175691 EST - 4.73 2.30 4.23
BF406167 EST - 4.69 4.51 7.33
BF523837 EST - 4.64 10.89 7.44
BE120246 EST - 4.62 5.85 3.70
NM_001107067 rhomboid 5 homolog 2 Rhbdf2 4.57 4.48 7.59
XM_001063498 hypothetical protein LOC682874 LOC682874 4.47 10.75 11.26 NM_001031647 dynein, axonemal, light intermediate
polypeptide 1 Dnali1 4.46 7.82 8.09
NM_001107702 Fc receptor-like S, scavenger receptor Fcrls 4.44 12.50 10.53
101
BI300548 EST - 4.43 4.82 3.91
NM_012849 gastrin Gast 4.40 5.81 4.33
NM_031686 sodium channel, voltage-gated, type VII,
alpha Scn7a 4.31 42.69 17.08
XM_001080773 Similar to hypothetical protein BC018697 RGD1565197 4.30 3.39 5.24 NM_001134555 complement component 1, r subcomponent C1r 4.24 4.26 8.08 XR_007575 similar to hypothetical protein FLJ23074 RGD1566400 4.23 18.89 10.14
AW527250 EST - 4.22 15.80 12.38
NM_001108322 T-box 1 Tbx1 4.20 4.34 2.31
BF413171 EST - 4.18 4.09 5.38
AI178343 EST - 4.18 7.35 7.44
BE113293 EST - 4.17 2.93 6.19
AI169061 EST - 4.16 4.20 5.78
BF410720 EST - 4.15 3.56 6.17
NM_001044289 similar to Protein EAN57 LOC686841 4.13 4.36 5.09
XM_001060527 laminin, alpha 5 Lama5 4.11 11.57 9.35
BF402613 EST - 4.10 3.96 5.59
NM_001034950 urinary protein 3 Rup3 4.10 4.21 4.27
NM_053293 glutathione S-transferase theta 1 Gstt1 4.06 5.33 6.31
BF286450 EST - 4.05 10.88 7.27
NM_001106620 leprecan-like 2 Leprel2 4.03 3.00 7.70
XM_001074223 Similar to PR domain containing 11 LOC690358 3.99 2.27 6.74 NM_001134933 cysteine-rich intestinal protein Crip 3.91 10.16 8.74
XM_001055507 similar to shippo 1 RGD1564322 3.91 8.63 7.91
NM_001014008 asporin Aspn 3.89 8.18 5.50
NM_173094 3-hydroxy-3-methylglutaryl-Coenzyme A
synthase 2 Hmgcs2 3.88 11.91 9.03
NM_001002813 cathepsin Q-like 2 Ctsql2 3.87 4.09 5.11
XM_001064742 hypothetical LOC289530 RGD1310384 3.86 3.10 2.81
BI296694 EST - 3.85 3.20 5.92
AI407549 EST - 3.82 5.95 7.98
NM_001108463 radial spokehead-like 2 Rshl2 3.81 5.27 6.01
AA955889 EST - 3.79 3.03 4.05
NM_012715 adrenomedullin Adm 3.79 4.10 4.17
BE108778 EST - 3.75 6.34 5.68
NM_001109024 DnaJ (Hsp40) homolog, subfamily C,
member 30 Dnajc30 3.74 5.49 6.54
BF386266 EST - 3.72 6.39 6.90
NM_138842 surfactant associated protein B Sftpb 3.70 2.54 4.14
NM_198746 killer cell lectin-like receptor, subfamily A,
member 5 Klra5 3.67 2.02 10.11
AI412344 EST - 3.64 12.53 8.89
XM_001063079 similar to Na+ dependent glucose
transporter 1 RGD1561777 3.63 5.73 5.83
NM_080768 tachykinin receptor 2 Tacr2 3.60 2.91 7.34
BI291326 EST - 3.59 12.88 8.26
NM_001106934 premature ovarian failure 1B Pof1b 3.59 4.43 3.21
NM_001024902 leucine rich repeat containing 56 Lrrc56 3.59 6.92 6.30 NM_031550 cyclin-dependent kinase inhibitor 2A Cdkn2a 3.59 2.70 3.37
BF418099 EST - 3.59 5.41 6.52
NM_022303 caspase recruitment domain family, member
9 Card9 3.58 3.50 2.29
AFFX-r2-Bs-dap-3 EST - 3.57 6.45 3.42
NM_145674 Glycoprotein, alpha-galactosyltransferase 1 Ggta1 3.56 5.21 5.70
AI137437 EST - 3.55 10.29 6.23
102
NM_001007009 similar to hypothetical protein MGC94915 3.54 10.75 9.08 NM_012588 insulin-like growth factor binding protein 3 Igfbp3 3.51 9.64 6.52
BE112417 EST - 3.51 2.43 6.88
NM_001014087 coiled-coil domain containing 67 Ccdc67 3.50 15.54 8.25
NM_080893 phosphodiesterase 11A Pde11a 3.49 3.54 3.60
NM_001109074 similar to novel protein RGD1565283 3.48 9.39 7.58
AI103063 EST - 3.48 2.33 6.09
NM_001114330 glutamate receptor, metabotropic 1 Grm1 3.45 2.92 5.89
NM_019292 carbonic anhydrase 3 Car3 3.44 3.26 6.28
AW531659 EST - 3.44 5.64 3.51
NM_022614 inhibin beta C Inhbc 3.43 3.23 6.29
XM_001057060 ADP-ribosylation factor-like 4C Arl4c 3.41 4.04 5.05
AA858815 EST - 3.40 2.39 3.21
NM_001013178 mediator complex subunit 20 Med20 3.39 2.23 3.47
BI280974 EST - 3.38 7.54 9.33
NM_001024750 polymerase (DNA-directed), delta 3,
accessory subunit Pold3 3.38 6.83 5.50
BM383972 EST - 3.37 3.78 5.44
XM_001059059 stromal antigen 2 Stag2 3.37 5.37 5.09
NM_053332 cubilin Cubn 3.34 5.73 6.36
AI058852 EST - 3.31 3.27 3.42
NM_001011947 retinoic acid induced 14 Rai14 3.30 2.34 3.44
AA859828 EST - 3.29 4.81 5.24
XM_001080515 atonal homolog 7 Atoh7 3.29 3.90 6.01
XM_001076288 coiled-coil domain containing 37 Ccdc37 3.27 5.68 6.89
BG381643 EST - 3.27 3.59 4.60
AI639305 EST - 3.26 5.09 4.73
BG373926 EST - 3.26 5.79 5.83
XM_001073195 hypothetical protein LOC686269 LOC686269 3.25 5.00 5.71 NM_001033655 dynein, axonemal, heavy chain 1 Dnahc1 3.25 5.73 5.99 NM_001107559 G protein-coupled receptor 123 Gpr123 3.23 10.38 8.61
BE120224 EST - 3.23 5.16 2.99
BE121176 EST - 3.23 2.09 5.16
NM_001100658 heat shock protein 9 Hspa9 3.22 2.88 2.60
NM_031235 Par-3 (partitioning defective 3) homolog Pard3 3.22 5.43 3.11
BF396578 EST - 3.22 4.08 6.05
NM_001008724 fibrinogen, alpha polypeptide Fga 3.20 3.47 4.14
NM_023091 gamma-aminobutyric acid (GABA-A)
receptor, subunit epsilon Gabre 3.20 3.91 7.46
NM_031826 fibrillin 2 Fbn2 3.20 7.58 6.46
AW532932 EST - 3.19 7.89 6.81
BE106592 EST - 3.17 5.00 5.16
NM_001109289 similar to RIKEN cDNA 1700012B09 RGD1561795 3.16 4.22 7.64
BF412370 EST - 3.16 3.99 3.46
AI237240 EST - 3.15 3.50 3.18
XM_001056519 similar to talin 2 RGD1565416 3.15 4.24 3.11
AI013206 EST - 3.14 4.09 5.20
NM_001012176 radial spoke head 1 homolog Rsph1 3.14 8.37 6.89
AI764498 EST - 3.14 4.82 5.83
NM_012620 serine (or cysteine) peptidase inhibitor, clade
E, member 1 Serpine1 3.13 2.11 7.58
BI281668 EST - 3.13 10.36 7.38
NM_001107692 ephrin A4 Efna4 3.13 5.07 6.72
XM_001058594 similar to Prefoldin subunit 3 (Von
Hippel-Lindau-binding protein 1) LOC681825 3.13 6.28 8.25
103
(VHL-binding protein 1) (VBP-1)AI412578 EST - 3.10 4.75 2.69
BF406860 EST - 3.10 2.02 3.26
NM_001108559 PRP3 pre-mRNA processing factor 3
homolog Prpf3 3.09 2.69 2.98
NM_001108585 similar to RIKEN cDNA A930018P22 RGD1563222 3.09 6.40 6.07
AA997980 EST - 3.08 4.85 3.62
XM_001061499 similar to Myb proto-oncogene protein
(C-myb) (predicted) RGD1560020 3.07 8.60 6.71
NM_031115 secretin receptor Sctr 3.07 4.93 4.52
AI176102 EST - 3.07 6.19 5.91
AW252092 EST - 3.06 2.49 5.59
NM_012760 pleiomorphic adenoma gene-like 1 Plagl1 3.05 9.17 5.35
NM_053762 zona pellucida glycoprotein 3 Zp3 3.04 5.08 3.40
NM_001002805 complement component 4a C4a 3.04 7.15 6.43
BF419834 EST - 3.04 2.56 3.33
BF399526 EST - 3.04 6.75 4.52
BF388150 EST - 3.03 3.09 3.71
BF412962 EST - 3.02 3.91 3.52
NM_001107680 myeloid leukemia factor 1 Mlf1 3.02 13.05 7.73
NM_001114330 glutamate receptor, metabotropic 1 Grm1 3.01 2.85 2.88 NM_001108037 retinol dehydrogenase 12
(all-trans/9-cis/11-cis) Rdh12 3.00 5.94 5.98
NM_019328 nuclear receptor subfamily 4, group A,
member 2 Nr4a2 2.97 2.87 4.92
NM_031502 amylase 2, pancreatic Amy2 2.96 3.94 2.25
AI144863 EST - 2.95 6.52 3.40
NM_001105991 ATPase, H+ transporting, lysosomal V1
subunit G3 Atp6v1g3 2.94 5.01 4.82
BE119364 EST - 2.94 5.40 6.04
NM_001106976 periplakin Ppl 2.93 4.63 5.08
XM_001077978 similar to hypothetical protein A730098P15 RGD1565726 2.93 12.21 7.20
NM_001108238 ankyrin repeat domain 12 Ankrd12 2.93 5.71 5.91
AA997660 EST - 2.93 2.93 2.85
NM_001106335 inner centromere protein Incenp 2.92 3.20 4.87
NM_001108074 fizzy/cell division cycle 20 related 1 Fzr1 2.91 2.09 3.25
BF398637 EST - 2.91 3.95 4.98
AI602005 EST - 2.90 4.45 5.55
NM_001110099 ret proto-oncogene Ret 2.89 5.01 4.39
XR_008690 Similar to GTL2, imprinted maternally
expressed untranslated RGD1566401 2.89 2.19 4.67
BM386570 EST - 2.89 7.77 5.26
XR_005460 similar to 2410024A21Rik protein RGD1304878 2.89 4.24 4.31
NM_001108055 adenylate kinase 7 Ak7 2.88 7.39 6.24
NM_030848 bone marrow stromal cell antigen 1 Bst1 2.88 3.69 4.77 NM_001106511 carboxypeptidase X (M14 family), member
1 Cpxm1 2.88 6.28 5.59
NM_001109613 hypothetical protein LOC690918 LOC690918 2.87 6.36 5.97
BM385125 EST - 2.87 2.56 3.67
NM_013112 apolipoprotein A-II Apoa2 2.86 2.85 2.10
AA923898 EST - 2.86 5.82 6.48
XM_001056805 similar to growth and
transformation-dependent protein LOC680351 2.86 3.69 3.14
NM_013059 alkaline phosphatase Alpl 2.86 3.09 5.70
AI171550 EST - 2.85 4.80 5.65
104
NM_031703 aquaporin 3 Aqp3 2.85 3.68 4.64
NM_053629 follistatin-like 3 Fstl3 2.85 4.28 6.08
AI007657 EST - 2.84 5.77 6.02
NM_017266 lactate dehydrogenase C Ldhc 2.84 4.04 4.43
AI535351 EST - 2.83 4.55 2.74
XM_001066354 gastrulation brain homeobox 2 Gbx2 2.82 4.73 4.09
NM_001106825 hypothetical LOC300751 RGD1311874 2.81 2.33 3.99
NM_001025770 testis specific gene A14 Tsga14 2.80 3.28 2.23
NM_001106100 ATP/GTP binding protein 1 Agtpbp1 2.79 2.82 3.16
NM_080581 ATP-binding cassette, sub-family C
(CFTR/MRP), member 3 Abcc3 2.79 2.34 4.04
XM_001069649 hypothetical protein LOC691223 LOC691223 2.79 6.64 5.67 XM_001066267 hypothetical protein LOC686032 LOC686032 2.79 7.24 8.67
BG374111 EST - 2.77 2.68 3.75
NM_183331 coagulation factor VIII F8 2.77 4.27 3.68
XR_007778 similar to BC040823 protein RGD1563798 2.77 2.61 2.51
NM_001009362 PAS domain containing serine/threonine
kinase Pask 2.77 4.07 3.76
NM_019236 hairy and enhancer of split 2 Hes2 2.76 2.93 3.11
NM_019264 protein kinase, cAMP-dependent,
regulatory, type 2, alpha Prkar2a 2.76 6.66 3.29
AI112040 EST - 2.74 3.02 3.78
NM_031577 growth hormone releasing hormone Ghrh 2.74 2.64 2.81
NM_001108535 cell division cycle and apoptosis regulator 1 Ccar1 2.74 3.40 5.10
AI111707 EST - 2.73 3.97 4.11
AW142608 EST - 2.73 6.42 4.92
NM_133288 ATPase, Ca++ transporting, plasma
membrane 3 Atp2b3 2.73 5.42 8.04
NM_001109223 wingless-type MMTV integration site
family, member 16 Wnt16 2.71 2.42 3.82
XM_001063752 RGD1563109 RGD1563109 2.71 6.04 5.37
NM_033231 acyl-CoA synthetase medium-chain family
member 3 Acsm3 2.71 7.78 5.27
NM_012692 cytochrome P450 IIA1 (hepatic steroid
hydroxylase IIA1) gene Cyp2a1 2.71 2.04 2.66
NM_022213 phosphatidylinositol 3 kinase, regulatory
subunit, polypeptide 3 Pik3r3 2.70 4.10 2.74
BI287343 EST - 2.70 3.43 4.22
NM_001130508 scleraxis Scx 2.70 4.27 4.59
NM_001108688 cytidine deaminase Cda 2.70 3.57 4.00
NM_001108508 EPS8-like 2 Eps8l2 2.70 2.18 2.53
XM_001074750 similar to RIKEN cDNA D330022A01 gene RGD1306603 2.70 5.28 5.28 NM_023021
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Kcnn4 2.69 5.73 3.06
NM_001108612 death inducer-obliterator 1 Dido1 2.69 4.50 3.83
XM_001065965 dynein, axonemal, heavy polypeptide 7 Dnah7 2.69 5.88 5.21 NM_017329 surfactant, pulmonary-associated protein A1 Sftpa1 2.67 2.72 2.02
AI231422 EST - 2.67 8.39 6.24
NM_001014171 ventricular zone expressed PH domain
homolog 1 Veph1 2.67 9.78 5.95
XM_001077447 Nuclear receptor co-repressor 1 Ncor1 2.67 2.01 2.97
NM_001126294 similar to hypothetical protein FLJ25416 RGD1559690 2.66 3.38 3.72
AI058581 EST - 2.66 3.37 4.17
NM_001107727 microsomal triglyceride transfer protein Mttp 2.65 3.25 3.39
105
NM_001013165 leucine rich repeat containing 23 Lrrc23 2.65 6.67 5.81
BE104952 EST - 2.65 2.43 3.66
NM_001108066 NCBI AT rich interactive domain 3A Arid3a 2.65 2.13 3.69
XM_001062557 Muscleblind-like 1 Mbnl1 2.65 2.55 2.72
NM_001110155 RGD1565611 RGD1565611 2.64 5.17 4.74
NM_001037643 Ubiquitin-conjugating enzyme E2Z Ube2z 2.64 4.33 3.05
NM_212459 ADP-ribosylation factor-like 9 Arl9 2.63 2.27 3.59
XM_001066855 ankyrin repeat domain 55 Ankrd55 2.63 3.41 4.27
AA859744 EST - 2.62 3.28 3.60
NM_177482 prostatic steroid binding protein C1 Psbpc1 2.61 3.27 2.58
NM_001012741 lipase, endothelial Lipg 2.60 2.64 3.32
BI296619 EST - 2.60 6.65 5.52
NM_022246 RAD50 Rad50 2.60 2.81 2.74
BF409110 EST - 2.59 5.90 5.61
AI137489 EST - 2.59 3.50 3.39
NM_001135119 angel homolog 2 Angel2 2.58 2.71 3.66
AI178692 EST - 2.58 2.42 6.37
NM_001002803 transporter 1, ATP-binding cassette,
sub-family B (MDR/TAP) Tap1 2.58 3.38 4.65
NM_001105864 Scavenger receptor class F, member 2 Scarf2 2.58 4.83 2.48 NM_001134801 similar to apolipoprotein L2 RGD1309808 2.57 2.11 3.99
XM_001061006 glycyl-tRNA synthetase Gars 2.57 3.43 4.46
NM_001085403 similar to Nkrp1f protein LOC683758 2.56 3.11 2.65
NM_001025032 CD96 antigen Cd96 2.55 3.12 2.19
BF388014 EST - 2.55 5.54 2.09
XM_001062555
similar to Probable
phospholipid-transporting ATPase ID (ATPase class I type 8B member 2)
LOC685152 2.54 2.09 3.13 NM_001012220 cation channel, sperm associated 2 Catsper2 2.54 6.69 4.56
BE119630 EST - 2.53 4.63 4.34
XM_001078035 similar to zinc finger protein 59 LOC687333 2.52 6.31 3.54 NM_001109478 non-metastatic cells 4, protein expressed in Nme4 2.52 7.20 5.71
BF413876 EST - 2.51 2.31 3.81
NM_133603 Potassium voltage-gated channel, Isk-related
subfamily, gene 2 Kcne2 2.51 3.63 3.94
AI105271 EST - 2.50 5.15 5.22
XM_001057601 dynein, axonemal, heavy polypeptide 12 Dnah12 2.50 7.46 5.19
BE109256 EST - 2.50 4.16 3.05
NM_012524 CCAAT/enhancer binding protein (C/EBP),
alpha Cebpa 2.49 2.52 2.01
AW528430 EST - 2.49 4.65 3.92
BI274778 EST - 2.48 12.15 4.85
BE108785 EST - 2.47 2.70 2.69
AA964532 EST - 2.47 5.82 4.63
BI300437 EST - 2.47 6.76 5.17
NM_012676 troponin T2, cardiac Tnnt2 2.47 2.80 3.82
NM_001106402 lipoma HMGIC fusion partner-like 2 Lhfpl2 2.47 3.62 4.23
BF418003 EST - 2.46 3.75 3.25
NM_012734 hexokinase 1 Hk1 2.46 6.77 5.78
NM_001002822 RT1 class Ib, locus Aw2 RT1-Aw2 2.45 4.60 4.64
NM_133614 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 Slc25a21 2.43 2.88 2.88
AI575421 EST - 2.43 5.19 4.38
BF563384 EST - 2.43 2.45 4.32
BF387010 EST - 2.41 2.15 3.43
106
BI292177 EST - 2.41 3.03 4.12
BF397224 EST - 2.41 4.13 4.12
NM_199093 serine (or cysteine) peptidase inhibitor, clade
G, member 1 Serping1 2.41 7.37 5.21
NM_001014188 ISY1 splicing factor homolog Isy1 2.40 3.69 2.92
AI169347 EST - 2.39 2.93 2.53
AW251736 EST - 2.39 4.78 2.42
BE096865 EST - 2.38 2.14 3.68
NM_001024316 GATA binding protein 5 Gata5 2.38 2.34 2.09
NM_021696 serine (or cysteine) peptidase inhibitor, clade
B, member 2 Serpinb2 2.38 2.18 2.65
NM_001107712 CTTNBP2 N-terminal like Cttnbp2nl 2.37 4.67 5.18
BF402577 EST - 2.37 3.03 4.52
NM_133573 G protein-coupled estrogen receptor 1 Gper 2.37 4.96 2.24
AI137817 EST - 2.37 2.57 2.64
NM_012920 calcium/calmodulin-dependent protein
kinase II, alpha Camk2a 2.36 2.10 2.32
XM_001068622 similar to testes development-related
NYD-SP22 isoform 1 RGD1561916 2.36 5.59 4.69
NM_181694 Rsb-66 protein Rsb66 2.36 3.74 4.32
AW530423 EST - 2.36 3.10 3.67
NM_001106319 Cysteinyl-tRNA synthetase Cars 2.35 4.23 4.16
NM_001107393 diaphanous homolog 1 Diap1 2.35 2.40 3.77
NM_001025681 tetratricopeptide repeat domain 23 Ttc23 2.35 4.30 5.07
NM_017318 protein tyrosine kinase 2 beta Ptk2b 2.34 2.61 3.17
XM_001069194 hypothetical LOC315072 RGD1311993 2.34 2.92 5.32
XM_001064653 ropporin 1-like Ropn1l 2.34 5.74 4.66
NM_053808 coagulation factor II (thrombin)
receptor-like 3 F2rl3 2.34 4.63 3.52
NM_001108588 solute carrier family 5 (sodium/glucose
cotransporter), member 12 Slc5a12 2.34 2.11 3.54
BF402073 EST - 2.34 3.41 4.75
AI548601 EST - 2.33 3.61 4.10
NM_001024275 Ras association (RalGDS/AF-6) domain
family 4 Rassf4 2.31 4.67 5.43
XM_001058430 ribosomal protein L3-like Rpl3l 2.31 2.05 3.52
NM_053734 neutrophil cytosolic factor 1 Ncf1 2.31 2.56 2.69
NM_001008871 serine peptidase inhibitor, Kazal type 4 Spink4 2.31 4.24 3.95
NM_031538 CD8 antigen, alpha chain Cd8a 2.30 3.40 3.95
NM_001024330 hypothetical gene supported by BC079424 LOC500227 2.30 3.44 3.98 NM_001034139 leucine rich repeat containing 8 family,
member E Lrrc8e 2.30 2.97 2.61
BF396077 EST - 2.29 2.00 3.08
NM_057149 tumor necrosis factor (ligand) superfamily,
member 11 Tnfsf11 2.29 5.24 2.11
AI716819 EST - 2.29 4.84 2.31
NM_013123 interleukin 1 receptor, type I Il1r1 2.28 2.96 3.83
BF552068 EST - 2.28 9.63 5.84
XM_228760 Transcription factor E3 Tcfe3 2.27 2.56 2.82
AW529671 EST - 2.27 2.47 2.95
BE096970 EST - 2.27 4.08 4.46
NM_212538 PHD finger protein 1 Phf1 2.26 2.46 3.29
AW527234 EST - 2.26 2.80 2.77
NM_053810 synaptosomal-associated protein 29 Snap29 2.26 2.26 3.00 XM_213732 paired immunoglobin-like type 2 receptor Pilra 2.26 2.56 2.46