業績集 ： 滋賀医科大学 薬理学講座
著者
滋賀医科大学 薬理学講座
発行年
2014-08-04
業
績
集
滋賀医科大学
薬理学講座
業績集
2014.7 現在
凡例： 連番（教室論文番号)
著者. 論文のタイトル. 雑誌・本等の名称. 発行年月;頁数.
原著
1(107)
Usui, H. and Toda, N. Cadmium-induced inhibition of twitches in isolated rat diaphragm. Jpn. J. Pharmacol. 1977;26: 768-769.
2(109)
Toda, N., Ozaki, T. and Ohta, T. Cerebrovascular sensitivity to vasoconstricting agents induced by subarachnoid hemorrhage and vasospam in dogs. J. Neurosurg. 1977;46(3): 296-303.
3(110)
Toda, N. Actions of bradykinin on isolated cerebral and peripheral arteries. Am. J. Physiol. 1977;232: H267-H274.
4(111)
Toda, N. and Hatano, Y. Alpha-adrenergic blocking action of fentanyl on the isolated aorta of the rabbit. Anesthesiology. 1977;46: 411-416.
5(113)
Hayashi, S. and Toda, N. Inhibition by Cd2+, verapamil and papaverine of Ca2+-induced contractions in isolated cerebral and peripheral arteries of dog. Br. J. Pharmacol. 1977;60: 35-43.
6(118)
Hatano, Y. and Toda, N. Influence of fentanyl on the chronotropic response of isolated rabbit atria to cholinergic and adrenergic stimulation. Jpn. J. Pharmacol. 1978;28: 105-114. 7(121)
Toda, N., Hatano, Y. and Hayashi, S. Modifications by stretches of the mechanical response of isolated cerebral and extracerebral arteries to vasoactive agents. Pflugers Arch. 1978;374: 73-77.
8(123)
Toda, N. Mechanical responses of isolated dog cerebral arteries to reduction of external K, Na, and Cl. Am. J. Physiol. 1978;234(4): H404-H411.
9(125)
Toda N. Miyazaki M. Angiotensin-converting. Jpn. J. Pharmacol. 1978;28: 495-497. 10(126)
Toda N, Hayashi S. Miyazaki M. Contractile responses of isolated dog mesenteric arteries to angiotensin I, II and III. Jpn. J. Pharmacol. 1978;28: 527-534.
11(127)
Toda N, Hayashi S. Hattori K. Analysis of the effect of tyramine and norepinephrine in isolated canine cerebral and mesenteric arteries. J. Pharmacol. Exp. Ther. 1978;205(2): 382-391.
Hayashi, S. and Toda, N. Age-related changes in the response of rabbit isolated aortae to vasoactive agents. Br. J. Pharmacol. 1978;64: 229-237.
13(129)
Toda, N., Hayashi, S., Hatano, Y., Okunishi, H. and Miyazaki, M. Selectivity and steric effects of metoprolol isomers on isolated rabbit atria, arteries and tracheal muscles. J. Pharmacol. Exp. Ther. 1978;207(2): 311-319.
14(130)
Toda, N. and Miyazaki, M. Response of isolated dog cerebral and peripheral arteries to prostaglandins after application of aspirin and polyphloretin phosphate. Stroke. 1978;9: 490-498.
15(134)
Fu, L.H.W. and Toda, N. Structure-activity relationship of 5-hydroxykynurenamine analogues in isolated dog cerebral arteries. Jpn. J. Pharmacol. 1979;29: 789-796.
16(137)
Toda, N. Acetylcholine-induced relaxation in isolated dog cerebral arteries. J. Pharmacol. Exp. Ther. 1979;209(3): 352-358.
17(138)
Miyazaki, M., Komori, T., Okunishi, H. and Toda, N. Inhibition of dog renin activity by pepstatin A. Jpn. Circ. J. 1979;43(9): 818-823.
18(139)
Toda, N. and Hatano, Y. Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries. Eur. J. Pharmacol. 1979;57: 231-238.
19(141)
Toda, N., Hayashi, S. and Miyazaki, M. Length-tension relationship of cerebral and peripheral arteries isolated from normotensive and spontaneously hypertensive rats. Jpn. Heart J. 1979;20(supple.1.): 255-257.
20(142)
Toda, N. and Hayashi, S. Age-dependent alteration in the response of isolated rabbit basilar arteries to vasoactive agents. J. Pharmacol. Exp. Ther. 1979;211(3): 716-721.
21(143)
Fu, L.H.W., Hayashi S. and Toda N. Effect of 5-hydroxytryptophol, a 5-hydroxytryptamine metabolite, on isolated cerebral arteries of the dog. Br. J. Pharmacol. 1980;68:17-18.
22(146)
Hayashi, S., Miyazaki, M. and Toda, N. Responsiveness to vasoactive agents of cerebral and mesenteric arteries isolated from control and reserpine-treated dogs. Br. J. Pharmacol. 1980;68: 473-478.
23(147)
Toda, N. Responses to prostaglandins H2 and I2 of isolated dog cerebral and peripheral arteries. Am. J. Physiol. 1980;238(Heart Circ. Physiol. 7): H111-H117.
Fukuda, S., Takeshita, H. and Toda, N. Modifications by lidocanine and its N-dealkylated metabolites of the response of the isolated rabbit aorta to transmural electrical stimulation. Anesthesiology. 1980;53: 106-112.
25(149)
Shimizu, K., Ohta, T. and Toda, N. Evidence for greater susceptibility of isolated dog cerebral arteries to Ca antagonists than peripheral arteries. Stroke. 1980;11(3): 261-266. 26(150)
Toda, N. Age-related changes in the transmembrane potential of isolated rabbit sino-atrial nodes and atria. Cardiovasc. Res. 1980;14(1): 58-63.
27(151)
Kinoshita, M., Takayama, Y., Kato, S., Mashiro, I., Mitsunami, K., Motomura, M., Kawakita, S., Mori, A., Sono, J., Okada, Y., Miyazaki, M., Okunishi, H. and Toda, N. Protection of coronary reperfusion injury by a calcium antagonist. Jpn. Circ. J. 1980;44(6): 461-466. 28(152)
Toda, N. and Hatano, Y. Contractile responses of canine tracheal muscle during exposure to fentanyl and morphine. Anesthesiology. 1980;53(2): 93-100.
29(153)
Hayashi, S. and Toda, N. Age-related alterations in the response of rabbit tracheal smooth muscle to agents. J. Pharmacol. Exp. Ther. 1980;214(3): 675-681.
30(156)
Toda, N., Shimizu K. and Ohta, T. Mechanism of cerebral arterial contraction induced by blood constituents. J. Neurosurg. 1980;53(3): 312-322.
31(157)
Toda, N. Mechanisms of ouabain-induced arterial muscle contraction. Am. J. Physiol. 1980;239(Heart Circ. Physiol. 8):Hl99-H205.
32(161)
Mori, A., Sono, J., Ando, F., Okada, Y., Kinoshita, M., Kawakita, S., Miyazaki M. Okunishi H. and Toda N. Effect of intra-aortic balloon pumping and calcium antagonists for reducing coronary reperfusion injury. Jpn. Circ. J. 1981;45(4): 491-426.
33(164)
Toda, N. Cardiotoxic and inotropic effects of ouabain on atria isolated from rabbits of different ages. Br. J. Pharmacol. 1981;72: 263-270.
34(165)
Toda, N. Non-adrenergic, non-cholinergic innervation in monkey and human cerebral arteries. Br. J. Pharmacol. 1981;72: 281-283.
35(166)
Toda, N. and Miyazaki, M. Angiotensin-induced relaxation in isolated dog renal and cerebral arteries. Am. J. Physiol. 1981;240(Heart Circ. Physiol. 9): H247-H254.
36(169)
Adachi, H., Toda, N., Hayashi, S., Noguchi, M., Suzuki, T., Torizuka, K., Yazima, H. and Koyama, K. Mechanism of the excitatory action of motilin on isolated rabbit intestine. Gastroenterology. 1981;80: 783-788.
Konishi, M., Toda, N. and Yamamoto, M. Different mechanisms of action of histamine in isolated arteries of the dog. Br. J. Pharmacol. 1981;74: 111-118.
38(177)
Toda, N., Konishi, M., Okunishi, H. and Miyazaki, M. Influence of disopyramide, compared with procainamide and quinidine, on isolated dog arteries in response to transmural stimulation and norepinephrine. J. Cardiovasc. Pharmacol. 1981;3: 1332-1341.
39(178)
Toda, N. Response of isolated monkey coronary arteries to catecholamines and to transmural electrical stimulation. Circ. Res. 1981;49: 1228-1236.
40(179)
Toda, N. Different responsiveness of a variety of isolated dog arteries to prostaglandin D2. Prostaglandins. 1982;23(1): 99-112.
41(180)
Hayashi, S. and Toda, N. Responses of isolated dog coronary arteries to tyramine. Jpn. J. Pharmacol. 1982;32(1): 47-54.
42(181)
Miyazaki, M., Okunishi, H. and Toda, N. Effects of elcatonin on plasma and urine electrolytes in infant beagles. Jpn. J. Pharmacol. 1982;32(1): 143-148.
43(184)
Fukuda, S., Tsuji, T., Murakawa, T., Takeshita, H. and Toda, N. Effects of mepivacaine on adrenergic neuroeffector junction of the isolated rabbit aorta. Anesth. Analg. 1982;61(9): 756-762.
44(186)
Toda, N. and Hayashi, S. Responses of canine coronary arteries to transmural electrical stimulation and nicotine. Eur. J. Pharmacol. 1982;80(1): 73-81.
45(187)
Toda, N. Potentiation by ouabain of the response to vasoconstrictor agents of isolated dog cerebral and mesenteric arteries soaked in Ca++-free media. J. Cardiovasc. Pharmacol. 1982; 4: 469-474.
46(188)
Ozaki, N., Kawakita, S and Toda, N. Effects of dobutamine on isolated canine cerebral, coronary, mesenteric, and renal arteries. J. Cardiovasc. Pharmacol. 1982; 47(4): 456-461. 47(189)
Toda, N., Okunishi, H., Taniyama, K, and Miyazaki, M. Responses to adenine nucleotides and related compounds of isolated dog cerebral, coronary and mesenteric arteries. Blood Vessels. 1982;19(5): 226-236.
48(190)
Toda. N., Okunishi, H. and Miyazaki, M. Length-passive tension relationships in cerebral and peripheral arteries isolated from spontaneously hypertensive and normotensive rats. Jpn. Circ. J. 1982;46(10): 1088-1094.
Toda, N. Relaxant responses to transmural stimulation and nicotine of dog and monkey cerebral arteries. Am. J. Physiol. 1982;243(Heart Circ. Physiol. 12): H145-H153. 50(192)
Toda. N., Konishi, M. and Miyazaki, M. Involvement of endogenous prostaglandin I2 in the vascular action of histamine in dogs. J. Pharmacol. Exp. Ther. 1982;223(1): 257-262. 51(193)
Toda. N., Usui, H., Osumi, S., Kanda, M. and Kitao, K. Influence of trimetazidine, an antianginal drug, on isolated dog arteries and veins. Arch. int. Pharmacodyn. Ther. 1982;260(2): 230-243.
52(194)
Toda. N. Mechanism of action of carbocyclic thromboxane A2 and its interaction with prostaglandin I2 and verapamil in isolated arteries. Circ. Res. 1982;51(6): 675-682.
53(199)
Yamamoto, M., Ohta, T. and Toda, N. Mechanisms of relaxant action of nicardipine, a new Ca++ -antagonist, on isolated dog cerebral and mesenteric arteries. Stroke. 1983;14(2): 270-275.
54(200)
Toda, N., Konishi, M., Miyazaki, M. and Komura, S. The effects of ethanol and acetaldehyde on dog arterial smooth muscle. J. Stud. Alcohol. 1983;44(1): l-16.
55(201)
Fu, L. H. W. and Toda, N. Analysis of the contractile response to serotonin and tryptamine of isolated dog cerebral, femoral and mesenteric arteries. Jpn. J. Pharmacol. 1983;33(2): 473-480.
56(204)
Hattori, K., Shimoura, K. and Toda, N. Modification by cadmium ions of 45calcium uptake by isolated rabbit aortae. Jpn. J. Pharmacol. 1983;33(3): 655-658.
57(209)
Toda, N. and Yamamoto, M. Modification of angiotensin II-induced relaxation by dipyridamole, phthalazinol and aspirin in isolated dog renal arteries. Jpn. J. Pharmacol. 1983;33(5): 1027-1034.
58(210)
Toda, N. Alpha adrenergic receptor subtypes in human, monkey and dog cerebral arteries. J. Pharmacol. Exp. Ther. 1983;26 (3): 861-868.
59(211)
Toda, N. Dopamine vasodilates human cerebral artery. Experientia. 1983;39(10): 1131-1132.
60(212)
Fukuda, S., Murakawa, T., Takeshita, H. and Toda, N. Direct effects of ketamine on isolated canine cerebral and mesenteric arteries. Anesth. Analg. 1983;62: 553-558.
61(213)
Toda N, Okunishi H, Okamura T, Miyazaki M. Effects of buflomedil on isolated dog arteries. Arch. int. Pharmacodyn. Ther. 1983; 266 (1): 117-130.
Toda, N. Heterogeneity in the response to dopamine of monkey cerebral and peripheral arteries. Am. J. Physiol. 1983;245(Heart Circ. Physiol. 14): H930-H936.
63(215)
Toda, N. Isolated human coronary arteries in response to vasoconstrictor substances. Am. J. Physiol. 1983; 245(Heart Circ. Physiol. 14): H937-H941.
64(216)
Miyazaki, M., Okunishi, H., Nishimura, K. and Toda, N. Vasucular anjiotenshin-converting enzyme activity in man and other species. Clin. Sci. 1984;66 (1): 39-45. 65(217)
Nakajima, M. and Toda, N. Neuroeffector actions of prostaglandin D2 on isolated dog mesenteric arteries. Prostaglandins. 1984;27(3) : 407-420.
66(218)
Toda, N. Endothelium-dependent relaxation induced by angiotensin II and histamine in isolated arteries of dog. Br. J. Pharmacol. 1984;81(2): 301-307.
67(219)
Toda N, Okamura T, Nakajima M, Miyazaki M. Modification by yohimbine and prazosin of the mechanical response of isolated dog mesenteric, renal and coronary arteries to transmural stimulation and norepinephrine. Eur. J. Pharmacol. 1984; 98(1): 69-78.
68(220)
Okamoto, S., Handa, H. and Toda, N. Role of intrinsic arachidonate metabolites in the vascular action of erythrocyte breakdown products. Stroke. 1984;15(1): 60-64.
69(221)
Toda, N., Nakajima, M., Nishimura, K. and Miyazaki, M. Responses of isolated dog arteries to amrinone. Cardiovasc. Res. 1984;18(3) : 174-182.
70(222)
Miwa, K. and Toda, N. Regional differences in the response to vasoconstrictor agents of dog and monkey isolated coronary arteries. Br. J. Pharmacol. 1984;82(1): 295-301.
71(223)
Okunishi, H., Miyazaki, M. and Toda, N. Evidence for a putatively new angiotensin II-generating enzyme in the vascular wall. J. Hypertension. 1984;2(3): 277-284.
72(225)
Toda, N. Responses of human, monkey and dog coronary arteries in vitro to carbocyclic thromboxane A2 and vasodilators. Br. J. Pharmacol. 1984;83(2): 399-408.
73(226)
Toda N, Okamura T, Miyazaki M. Heterogeneity in the response to vasoconstrictors of isolated dog proximal and distal middle cerebral arteries. Eur. J. Pharmacol. 1984;106(2): 291-299.
74(227)
Toda N, Miyazaki M, Okamura T. Alpha adrenoceptor subtype responsible for dopamine-induced mesenteric vein contraction. Jpn. J. Pharmacol. 1984;36(2): 253-255.
Okamura T, Toda N, Inagami T. Renin in cultured cells of neural crest origin. Jpn. Circ. J. 1984;48(11): 1225-1227.
76(230)
Toda, N. and Miyazaki, M. Heterogenous responses to vasodilators of dog proximal and distal middle cerebral arteries. J. Cardiovasc. Pharmacol. 1984;6(6): 1230-1237.
77(231)
Toda, N. Calcium independent contraction induced by iodoacetic acid in isolated cerebral arteries. Stroke. 1984;15(3): 475-480.
78(232)
Toda, N. Pharmacological assessment of cerebral and coronary vasospasm. Trends in Pharmacol. Sci. 1985;6(2): 85-87.
79(233)
Toda, N. Reactivity in human cerebral artery: species variation. Fed. Proc. 1985;44(2): 326-330.
80(234)
Narumiya, S. and Toda, N. Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues. Br. J. Pharmacol. 1985;85(2): 367-375.
81(235)
Miyazaki, M., Yamamoto, M. and Toda, N. Interaction between non-steroidal antiinflammatory agents and sodium salicylate in the relaxant response of dog renal arteries to angiotensin II. Arch. int. Pharmacodyn. Ther. 1985;274(2): 210-222.
82(236)
Miwa, K. and Toda, N. The regional difference of relaxations induced by various vasodilators in isolated dog coronary and mesenteric arteries. Jpn. J. Pharmacol. 1985;38(3): 313-320.
83(240)
Miyazaki, M., Morishita, S. and Toda, N. Vasodilator effect of indapamide in dog mesenteric vasculature. Jpn. J. Pharmacol. 1985;39(3): 402-405.
84(241)
Toda N, Okamura T, Shimizu I, Tatsuno Y. Postmortem functional changes in coronary and cerebral arteries from humans and monkeys. Cardiovasc. Res. 1985;19(11): 707-713. 85(243)
Toda N, Miyazaki M, Okamura T. Vascular neuroeffector function in two-kidney, one clip hypertensive dogs. J. Hypertension. 1985;3(5): 503-509.
86(244)
Toda, N., Nakajima, S., Miyazaki, M. and Ueda, M. Vasodilatation induced by pinacidil in dogs. Comparison with hydralazine and nifedipine. J. Cardiovasc. Pharmacol. 1985;7(6): 1118-1126.
87(245)
Nakajima, M. and Toda, N. Prejunctional and postjunctional actions of prostaglandins F2α and I2 and carbocyclic thromboxane A2 in isolated dog mesenteric arteries. Eur. J. Pharmacol. 1986;120(3): 309-318.
Shimizu, I. and Toda, N. Analysis of ouabain-induced contractions in isolated coronary arteries. Jpn. J. Pharmacol. 1986;40(2): 257-263.
89(249)
Okamura T, Miyazaki M, Toda N. Responses of isolated dog blood vessels to glucagon. Eur. J. Pharmacol. 1986;125(3): 395-401.
90(250)
Shimizu, I., Miyazaki, M. and Toda, N. Responsiveness to vasoconstrictor and dilator agents of senescent beagle cerebral arteries. Jpn. J. Pharmacol. 1986;41(4): 541-544.
91(252)
Toda, N. α -Adrenoceptor subtypes and diltiazem actions in isolated human coronary arteries. Am. J. Physiol. 1986;250(Heart Circ. Physiol. 19): H718-H724.
92(253)
Okamura T, Miyazaki M, Inagami T, Toda N. Vascular renin-angiotensin system in two-kidney, one-clip hypertensive rats. Hypertension. 1986;8(7): 560-565.
93(254)
Toda N, Shimizu I, Okamura T, Miyazaki M. Age-dependent change in the response of isolated beagle cerebral arteries to vasoactive agents. J. Cardiovasc. Pharmacol. 1986; 8(4): 681-688.
94(255)
Toda N, Okamura T, Miyazaki M. Age-dependent changes in the response of isolated beagle coronary arteries to transmural electrical stimulation and catecholamines. J. Pharmacol. Exp. Ther. 1986;238(1): 319-326.
95(256)
Toda N, Nakajima M, Okamura T, Miyazaki M. Interactions of thromboxane A2 analogs and prostaglandins in isolated dog arteries. J. Cardiovasc. Pharmacol. 1986; 8(4): 818-825.
96(257)
Miyazaki, M. and Toda, N. Endothelium-dependent changes in the responses to vasoconstrictor substances of isolated dog mesenteric veins. Jpn. J. Pharmacol. 1986;42(2): 309-316.
97(258)
Toda, N. Mechanisms of Histamine-lnduced relaxation in lsolated monkey and dog coronary arteries. J. Pharmacol. Exp. Ther. 1986;239(2): 529-535.
98(259)
Toda, N., Miyazaki, M., Etoh, Y., Kubota, T. and Iizuka, K. Human renin inhibiting dipeptide. Eur. J. Pharmacol. 1986;129(3): 393-396.
99(260)
Shimizu, I. and Toda, N. Alterations with age of the response to vasodilator agents in isolated mesenteric arteries of the beagle. Br. J. Pharmacol. 1986;89(4): 769-778.
100(261)
Akiba, T., Miyazaki, M. and Toda, N. Vasodilator actions of TRK-100, a new prostaglandin I2 analogue. Br. J. Pharmacol. 1986; 89(4): 703-711.
Miyazaki M, Okamura T, Okunishi H, Toda N. Vascular angiotensin converting enzyme in the development of renal hypertension. J. Cardiovasc. Pharmacol. 1986;8(suppl. 10): s58-s61.
102(264)
Toda, N. and Shimizu, I. Neuroeffector function in mesenteric arteries isolated from beagles of different ages. J. Pharmacol. Exp. Ther. 1987;240(1): 223-227.
103(266)
Toda N, Bian K, Akiba T, Okamura T. Heterogeneity in mechanisms of bradykinin action in canine isolated blood vessels. Eur. J. Pharmacol. 1987;135(3): 321-329.
104(267)
Nishimura, K., Miyazaki, M., Okunishi, H. and Toda, N. Hypotensive effect of SA446, an angiotensin converting enzyme inhibitor, in 2-kidney, 1-clip renal hypertensive and normotensive dogs. Jpn. J. Pharmacol. 1987;43(4): 379-387.
105(268)
Toda, N. and Miyazaki, M. Senescent beagle coronary arteries in response to catecholamines and adrenergic nerve stimulation. J. Gerontol. 1987;42(2): 210-218.
106(272)
Miyazaki M, Okunishi H, Okamura T, Toda N. Elevated vascular angiotensin converting enzyme in chronic two-kidney, one clip hypertension in the dog. J. Hypertension. 1987;5(2): 155-160.
107(273)
Miyazaki M, Okamura T, Okunishi H, Toda N. Possible role of vascular angiotensin converting enzyme in the genesis of hypertension. Clin. Exp. Hypertension. 1987;Part A9(2&3): 435-440.
108(274)
Toda, N. Mechanism of histamine actions in human coronary arteries. Circ. Res. 1987;61(2): 280-286.
109(276)
Toda, N., Bian, K. and Inoue, S. Age-related changes in the response to vasoconstrictor and dilator agents in isolated beagle coronary arteries. Naunyn-Schmiedeberg’s Arch. Pharmacol. 1987;336: 359-364.
110(277)
Okunishi H, Miyazaki M, Okamura T, Toda N. Different distribution of two types of angiotensin II-generating enzymes in the aortic wall. Biochem. Biophys. Res. Commun. 1987;149(3): 1186-1192.
111(278)
Toda N, Inoue S, Bian K, Okamura T. Endothelium-dependent and -independent responses to prostaglandin H2 and arachidonic acid in isolated dog cerebral arteries. J. Pharmacol. Exp. Ther. 1988;244(1): 297-302.
112(279)
Okamura T, Nakajima M, Toda N. Neuroeffector actions of thromboxane B2 in dog isolated mesenteric arteries. Br. J. Pharmacol. 1988;93(2): 367-374.
Toda, N. Hemolysate inhibits cerebral artery relaxation. J. Cerebral Blood Flow & Metab. 1988;8(1): 46-53.
114(282)
Toda, N. Responsiveness of isolated monkey coronary arteries contracted with α1 and α2,-adrenoceptor agonists to diltiazem. Eur. J. Pharmacol. 1988;147(2): 291-293.
115(283)
Inoue, S., Kinoshita, M. and Toda, N. Modification by severe hypoxia and diltiazem of dog coronary artery contractions in vitro. Eur. J. Pharmacol. 1988;148(1): 69-77.
116(284)
Toda N, Inoue S, Okamura T, Okunishi H. Mechanism underlying relaxations caused by prostaglandins and thromboxane A2 analog in isolated dog arteries. J. Cardiovasc. Pharmacol. 1988;11(3): 354-362.
117(285)
Toda, N. and Onoue, H. Prostaglandin F2α-induced contraction in isolated dog cerebral, coronary and mesenteric arteries soaked in excess potassium. Jpn. J. Pharmacol. 1988;47(2): 204-207.
118(286)
Minami, Y. and Toda, N. Comparison of the response to angiotensin II of isolated dog coronary and mesenteric arteries of proximal and distal portions. Arch. int. Pharmacodyn. Ther. 1988;293(1): 186-195.
119(287)
Toda, N., Minami, Y. and Onoue, H. Extraluminally applied acetylcholine and oxyhemoglobin on the release and action of EDRF. Eur. J. Pharmacol. 1988;151: 123-126. 120(289)
Lu W, Okamura T, Bian K, Inatomi A, Toda N. Prostaglandins involved in contractions by angiotensin II and bradykinin of isolated dog sphincter pupillae. Br. J. Pharmacol. 1988;95(2): 544-550.
121(290)
Toda, N., Inoue, S. and Okunishi, H. Prejunctional alpha adrenoceptor and angiotensin receptor function in isolated human, monkey and dog arteries. J. Pharmacol. Exp. Ther. 1988;246(2): 662-666.
122(291)
Inoue, S., Kinoshita, M. and Toda, N. Different inhibition by vasodilators of coronary artery contraction. Arch. int. Pharmacodyn. Ther. 1988;295(1): 181-193.
123(294)
Toda, N., Miyazaki, M. and Hazama, F. Functional and histological changes in mesenteric arteries and aortas from monkeys fed a high cholesterol diet. Jpn. J. Pharmacol. 1988;48(4): 441-451.
124(295)
Okamura T, Miyazaki M, Okunishi H, Toda N. Pathophysiological role of the vascular renin-angiotensin system in renal hypertensive rats. Clin. Exp. Hypertension. 1988;A10(6): 1293-1294.
Onoue, H., Nakamura, N. and Toda, N. Endothelium-dependent and -independent responses to vasodilators of isolated dog cerebral arteries. Stroke. 1988;19(11): 1388-1394. 126(299)
Bian, K. and Toda, N. Reoxygenation and calcium-induced cerebroarterial contractions as affected by vasodilator agents. J. Cerebral Blood Flow & Metab. 1988;8(6): 808-815.
127(300)
Bian, K. and Toda, N. Effects of sophoramine, an alkaloid from Sophora alopecuroides on isolated dog blood vessels. J. Ethnopharmacol. 1988;24: 167-178.
128(302)
Miyazaki, M., Okamura, T. and Toda, N. Role of vascular angiotensin converting enzyme in hypertension. J. Hypertension. 1988;6(Suppl. 3): s13-s15.
129(304)
Toda N, Okunishi H, Okamura T. Responses to dopamine of isolated human gastroepiploic arteries. Arch. int. Pharmacodyn. Ther. 1989;297(1): 86-97.
130(305)
Bian, K. and Toda, N. Vasodilator actions of flunarizine in isolated dog cerebral and extracerebral arteries. Jpn. J. Pharmacol. 1989;49(1): 83-94.
131(306)
Okamura T, Inoue S, Minami Y, Okunishi H, Toda N. Role of endothelium in the response to prostaglandin H2 in isolated dog arteries. Jpn. J. Pharmacol. 1989;49(4) : 511-521. 132(309)
Onoue, H., Nakamura, N. and Toda, N. Prolonged exposure to oxyhemoglobin modifies the response of isolated dog middle cerebral arteries to vasoactive substances. Stroke. 1989;20(5): 657-663.
133(310)
Inoue S, Bian K, Okamura T, Okunishi H, Toda N. Mechanisms of action of eperisone on isolated dog saphenous arteries and veins. Jpn. J. Pharmacol. 1989;50(3) : 271-282.
134(311)
Minami, Y., Onoue, H. and Toda, N. Extraluminally applied acetylcholine and substance P on the release of EDRF. Jpn. J. Pharmacol. 1989;50(3): 362-365.
135(312)
Okamura T, Minami Y, Toda N. Endothelium-dependent and -independent mechanisms of action of acetylcholine in monkey and dog isolated arteries. Pharmacology. 1989;38(5): 279-288.
136(313)
Okamura T, Inoue S, Toda N. Action of atrial natriuretic peptide (ANP) on dog cerebral arteries: evidence that neurogenic relaxation is not mediated by release of ANP. Br. J. Pharmacol. 1989;97(4): 1258-1264.
Miyazaki, M., Etoh, Y., Iizuka, K. and Toda, N. An orally active renin inhibitor: cyclohexylnorstatine-containing dipeptide (KRI-1314). J. Hypertension. 1989;7(Suppl.2): s25-s27.
138(315)
Toda, N., Hatano, Y. and Mori, K. Mechanisms underlying response to hypercapnia and bicarbonate of isolated dog cerebral arteries. Am. J. Physiol. 1989;257(Heart Circ. Physiol.26): H141-H146.
139(318)
Hatano, Y., Nakamura, K., Moriyama, S., Mori, K. and Toda, N. The contractile responses of isolated dog cerebral and extracerebral arteries to oxybarbiturates and thiobarbiturates. Anesthesiology. 1989;71(1): 80-86.
140(321)
Minami, Y. and Toda, N. Possible involvement of 5-lipoxygenase products in the generation of endothelium-derived relaxing factor. J. Pharmacol. Exp. Ther. 1989;250(3): 1055-1060.
141(322)
Toda N, Okamura T. Endothelium-dependent and -independent responses to vasoactive substances of isolated human coronary arteries. Am. J. Physiol. 1989; 257(Heart Circ. Physiol.26): H988-H995.
142(323)
Toda N, Okamura T. Modification by magnesium of dog cerebroarterial contraction. J. Vasc. Med. Biol. 1989;1(6): 354-360.
143(325)
Toda N, Okamura T. Modification by L-NG-monomethyl arginine (L-NMMA) of the response to nerve stimulation in isolated dog mesenteric and cerebral arteries. Jpn. J. Pharmacol. 1990;52(10):170-173.
144(327)
Baba, H., Fujimura, M. and Toda, N. Mechanism of inhibitory action of peptide YY on cholecystokinin-induced contractions of isolated dog ileum. Regulatory Peptides. 1990;27(2): 227-235.
145(328)
Toda, N. Mechanisms of contracting action of oxyhemoglobin in isolated monkey and dog cerebral arteries. Am. J. Physiol. 1990;258(Heart Circ. Physiol.27): H57-H63.
146(329)
Toda, N. Mechanisms underlying responses to histamine of isolated monkey and human cerebral arteries. Am. J. Physiol. 1990;258(Heart Circ. Physiol.27): H311-H317.
147(330)
Toda N, Ayaziki K, Okamura T. Modifications by endogenous prostaglandins of angiotensin II-induced contractions in dog and monkey cerebral and mesenteric arteries. J. Pharmacol. Exp. Ther. 1990;252(1): 374-379.
Toda N, Inoue S, Okunishi H, Okamura T. Intra- and extraluminally-applied acetylcholine on the vascular tone or the response to transmural stimulation in dog isolated mesenteric arteries. Naunyn-Schmiedeberg’s Arch. Pharmacol. 1990;341(1-2): 30-36.
149(332)
Toda, N. and Ayajiki, K. Cholinergic prejunctional inhibition of vasodilator nerve function in bovine basilar arteries. Am. J. Physiol. 1990;258(Heart Circ. Physiol.27): H983-H986.
150(333)
Toda N, Okamura T. Beta adrenoceptor subtype in isolated human, monkey and dog epicardial coronary arteries. J. Pharmacol. Exp. Ther. 1990;253(2): 518-524.
151(334)
Okamura T, Okunishi H, Ayajiki K, Toda N. Conversion of angiotensin I to angiotensin II in dog isolated renal artery: Role of two different angiotensin II-generating enzymes. J. Cardiovasc. Pharmacol. 1990;15(3): 353-359.
152(335)
Toda N, Okamura T. Comparison of the response to 5-carboxamidotryptamine and serotonin in isolated human, monkey and dog coronary arteries. J. Pharmacol. Exp. Ther. 1990;253(2): 676-682.
153(336)
Okamura T, Yoshida K, Toda N. Suppression by methylene blue of prostaglandin I2 synthesis in isolated dog renal arteries. J. Pharmacol. Exp. Ther. 1990;254(1):198-203.
154(337)
Toda N, Baba H, Okamura T. Role of nitric oxide in non-adrenergic, non-cholinergic nerve-mediated relaxation in dog duodenal longitudinal muscle strips. Jpn. J. Pharmacol. 1990;53(2): 281-284.
155(340)
Toda N, Okamura T. Possible role of nitric oxide in transmitting information from vasodilator nerve to cerebroarterial muscle. Biochem. Biophys. Res. Commun. 1990;170(1): 308-313.
156(341)
Toda N, Minami Y, Okamura T. Inhibitory effects of L-NG-nitro-arginine on the synthesis of EDRF and the cerebroarterial response to vasodilator nerve stimulation. Life Sci. 1990;47(4): 345-35l.
157(342)
Toda N, Okamura T. Mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries. Am. J. Physiol. 1990;259(Heart Circ. Physiol.28): H1511-H1517.
158(344)
Ayajiki, K. and Toda, N. Isolated bovine cerebral arteries from rostral and caudal regions: distinct responses to adrenoceptor agonists. Eur. J. Pharmacol. 1990;191(3,4): 417-425. 159(347)
Kawakami, M., Kodama, N. and Toda, N. Suppression of the cerebral vasospastic actions of oxyhemoglobin by ascorbic acid. Neurosurgery. 1991;28(1): 33-40.
Toda, N., Kawakami, M. and Yoshida, K. Constrictor action of oxyhemoglobin in monkey and dog basilar arteries in vivo and in vitro. Am. J. Physiol. 1991;260(Heart Circ. Physiol.29): H420-H425.
161(349)
Toda N, Yoshida K, Okamura T. Analysis of the potentiating action of NG-nitro-L-arginine on the contraction of the dog temporal artery elicited by transmural stimulation of noradrenergic nerves. Naunyn-Schmiedeberg’s Arch. Pharmacol. 1991;343(2): 221-224.
162(350)
Toda N, Kawakami M, Yamazaki M, Okamura T. Comparision of endothelium-dependent responses of monkey cerebral and temporal arteries. Br. J. Pharmacol. 1991;102(4): 805-810.
163(351)
Toda, N., Kawakami, M. and Kodama, N. Prevention by nicardipine of dog basilar artery spasm caused by oxyhemoglobin in vivo and in vitro. Eur. J. Pharmacol. 1991;195(1): 175-177.
164(352)
Yoshida, K., Yamazaki, Y. and Toda, N. Different modulation by cyclooxygenase inhibitors of the response to angiotensin II in monkey arteries and veins. Jpn. J. Pharmacol. 1991;55(4): 469-475.
165(354)
Saito, A., Handa, J. and Toda, N. Reactivity to vasoactive agents of canine basilar arteries exposed to experimental subarachnoid hemorrhage. Surg. Neurol. 1991;35(6): 461-467. 166(355)
Toda, N. Age-related changes in responses to nerve stimulation and catecholamines in isolated monkey cerebral arteries. Am. J. Physiol. 1991;260(Heart Circ. Physiol.29): Hl443-H1448.
167(356)
Inoue M, Okamura T, Toda N. Influence of methylene blue and oxyhemoglobin on mammalian vascular responses to sodium nitroprusside and nitroglycerin. Arch. int. Pharmacodyn. Ther. 1991;311(1): 104-121.
168(358)
Yamazaki, M. and Toda, N. Comparison of responses to angiotensin II of dog mesenteric arteries and veins. Eur. J. Pharmacol. 1991;201(2-3): 223-229.
169(360)
Toda N, Okamura T. Suppression by NG - monomethyl ‐ L ‐ arginine of cerebroarterial responses to nonadrenergic, noncholinergic vasodilator nerve stimulation. J. Cardiovasc. Pharmacol. 1991;17(Suppl.3): S234-S237.
170(361)
Okamura T, Yamazaki M, Toda N. Responses to dopamine of isolated human and monkey veins compared with those of the arteries. J. Pharmacol. Exp. Ther. 1991;258(l): 275-279.
Toda N, Okamura T. Role of nitric oxide in neurally induced cerebroarterial relaxation. J. Pharmacol. Exp. Ther. 1991;258(3): l027-l032.
172(364)
Toda, N., Tanobe, Y. and Baba, H. Suppression by NG - nitro‐L - arginine of relaxations induced by non‐adrenergic, non‐cholinergic nerve stimulation in dog duodenal longitudinal muscle. Jpn. J. Pharmacol. 1991;57(4): 527-534.
173(366)
Toda, N. Human coronary, internal mammary, and gastroepiploic artery reactivity. Ann. Thorac. Surg. 1991;52(6): 1211-1212.
174(367)
Toda N, Kitamura Y, Okamura T. New idea on the mechanism of hypertension: Suppression of nitroxidergic vasodilator nerve function. J. Vasc. Med. Biol. 1991;3(4): 235-241. 175(369)
Toda N, Okamura T. Reciprocal regulation by putatively nitroxidergic and adrenergic nerves of monkey and dog temporal arterial tone. Am. J. Physiol. 1991; 261(Heart Circ. Physiol.27): Hl740-Hl745.
176(371)
Toda N, Okamura T. Mechanism of neurally induced monkey mesenteric artery relaxation and contraction. Hypertension. 1992;19(2): 161-166.
177(372)
Toda N, Baba H, Tanobe Y, Okamura T. Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle. J. Pharmacol. Exp. Ther. 1992;260(2): 697-701. 178(373)
Ayajiki, K. and Toda, N. Regional difference in the response mediated by β１ -adrenoceptor subtype in bovine cerebral arteries. J. Cerebral Blood Flow & Metab. 1992;12( 3 ) : 507-513.
179(374)
Okamura T, Aimi Y, Kimura H, Murakami K, Toda N. Existence of renin in the endothelium of human artery. J. Hypertension. 1992;10(1) : 49-53.
180(375)
Toda, N. EDRF in human coronary arteries. Jpn. Circ. J. 1992;56(2): 159-161. 181(377)
Toda, N., Matsumoto, T. and Yoshida, K. Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. Am. J. Physiol. 1992;262(Heart Circ. Physiol.3) : H678-H683.
182(378)
Toda N, Ayajiki K, Toda H, Hatano Y, Okamura T. Mechanism underlying mannitol-induced relaxation in isolated monkey cerebral arteries. Am. J. Physiol. 1992;262(3Pt2): H897-H902.
Toda N, Okamura T. Different susceptibility of vasodilator nerve, endothelium and smooth muscle functions to Ca++ antagonists in cerebral arteries. J. Pharmacol. Exp. Ther. 1992;261(1): 234-239.
184(385)
Okamura. T., Nishikawa. M., Yoshida K. and Toda, N. AE0047, a new dihydropyridine Ca2+ entry blocker, inhibits the responses to adrenergic nerve stimulation and substance P in dog mesenteric arteres. Eur. J. Pharmacol. 1992;220(1): 27-33.
185(386)
Okamura T, Matsumoto T, Ikemoto F, Toda N. Mechanisms of the biphasic responses to endothelin-3 in dog coronary arteries. Br. J. Pharmacol. 1992;l07(4): 1037-1041.
186(387)
Okamura T, Wang Y, Toda N. Local generation and action of angiotensin II in dog iris sphincter muscle. Exp. Eye. Res. 1992;55(4): 563-568.
187(388)
Kimura, T. Yoshida, Y. and Toda, N. Mechanisms of relaxation induced by prostaglandins in isolated canine uterine arteries. Am. J. Obstet. Gynecol. 1992;167(5): 1409-1416.
188(389)
Ayajiki K, Okamura T, Toda N. Involvement of nitric oxide in endotheliurn-dependent, phasic relaxation caused by histamine in monkey cerebral arteries. Jpn. J. Pharmacol. 1992;60 (4): 357-362.
189(394)
Toda N, Ayajiki K, Yoshida K, Kimura H, Okamura T. Impairment by damage of the pterygopalatine ganglion of nitroxidergic vasodilator nerve function in canine cerebral and retinal arteries. Circ. Res. 1993;72(1): 206-213.
190(395)
Toda, N., Kitamura, Y. and Okamura, T. Neural mechanism of hypertension by nitric oxide synthase inhibitor in dogs. Hypertension. 1993;21(1): 3-8.
191(396)
Toda, N. Mediation by nitric oxide of neurally - induced human cerebral artery relaxation. Experientia. 1993;49(1):51-53.
192(397)
Wang Y, Okamura T, Toda N. Mechanisms of histamine - induced relaxation in external and internal ophthalmic arteries. Invest. Ophthal. Vis. Sci. 1993;34(1): 41-48.
193(398)
Matsumoto, T., Kinoshita, M. and Toda, N. Mechanisms of endothelium - dependent responses to vasoactive agents in isolated porcine coronary arteries. J. Cardiovasc. Pharmacol. 1993; 22(2) : 228-234.
194(399)
Yoshida K, Okamura T, Toda N. Potentiation by hypoxia of contractions caused by angiotensin II in dog and monkey cerebral arteries. Stroke. 1993;24(3): 421-426.
Shimamura, K., Fujisawa, A., Toda, N. and Sunano, S. Effects of NG nitro L -arginine on electrical and mechanical responses to stimulation of non-adrenergic, non-cholinergic inhibitory nerves in circular muscle of the rat gastric fundus. Eur. J. Pharmacol. 1993;231(1): 103-109.
196(401)
Shiraishi, S., Mori, A. and Toda, N. Comparison of endothelium - dependent responses of canine internal thoracic and coronary arteries. Jpn. J. Pharmacol. 1993;61(3): 243-250. 197(402)
Ayajiki K, Okamura T, Toda N. Nitric oxide mediates, and acetylcholine modulates, neurally induced relaxation of bovine cerebral arteries. Neuroscience. 1993;54(3): 819-825. 198(403)
Zhang J-X, Okamura T, Toda N. Potentiation by extraluminal and intraluminal NG-nitro - L-arginine of neurally - induced pressor response of of mesenteric artery segments. Hypertens Res. 1993;16(1): 29-32.
199(405)
Toda N, Ayajiki K, Okamura T. Cerebroarterial relaxations mediated by nitric oxide derived from endothelium and vasodilator nerve. J. Vasc. Res. 1993;30(2): 61-67.
200(406)
Matsumoto T, Okamura T, Kinoshita M, Toda N. Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries. Eur. J. Pharmacol. 1993;237(1): 31-37.
201(408)
Toda N, Ayajiki K, Okamura T. Neural mechanism underlying basilar arterial constriction by intracisternal L-NNA in anesthetized dogs. Am. J. Physiol. 1993;265(1 Pt 2) : H103-H107.
202(409)
Toda N, Ayajiki K, Enokibori M, Okamura T. Monkey cerebral arterial relaxation caused by hypercapnic acidosis and hypertonic bicarbonate. Am. J. Physiol. 1993;265(3Pt2): H929-H933.
203(410)
Toda N, Enokibori M, Matsumoto T, Okamura T. Responsiveness to dopamine of isolated epicardial coronary arteries from humans, monkeys, and dogs. Anesth. Analg. 1993;77(3): 526-532.
204(411)
Okamura T, Enokibori M, Toda N. Neurogenic and non-neurogenic relaxations caused by nicotine in isolated dog superficial temporal artery. J. Pharmacol. Exp. Ther. 1993;266(3): 1416-1421.
205(412)
Kitamura Y, Okamura T, Kani K, Toda N. Nitric oxide-mediated retinal arteriolar and arterial dilatation induced by substance P. Invest. Ophthal. Vis. Sci. 1993;34(10): 2859-2865.
Toda N, Ayajiki K, Okamura T. Endothelial modulation of contractions caused by oxyhemoglobin and NG-nitro-L-arginine in isolated dog and monkey cerebral arteries. Stroke. 1993;24(10): 1584-1589.
207(419)
Etoh, Y., Miyazaki, M., Saitoh, H. and Toda, N. KRl-1314: An orally effective inhibitor of human renin. Jpn. J. Pharmacol. 1993;63(1) : 109-119.
208(422)
Wang Y, Okamura T, Toda N. Mechanisms of acetylcholine-induced relaxation in dog external and internal ophthalmic arteries. Exp. Eye. Res. 1993;57(3): 275-281.
209(423)
Toda N, Okamura T. Respons to perivascular nerve stimulation of distal temporal arteries from dogs and monkeys. J. Cardiovasc. Pharmacol. 1993; 22(5): 744-749.
210(424)
Yoshida K, Okamura T, Kimura H, Bredt D S, Snyder S H, Toda N. Nitric oxide synthase-immunoreactive nerve fibers in dog cerebral and peripheral arteries. Brain Res. 1993;629(1): 67-72.
211(429)
Enokibori M, Okamura T, Toda N. Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries. Br. J. Pharmacol. 1994;111(1): 77-82. 212(430)
Okamura T, Toda N. Inhibition by calmodulin antagonists of the neurogenic relaxation in cerebral arteries. Eur. J. Pharmacol. 1994;256(1). 79-83.
213(431)
Toda N, Kimura T, Yoshida K, Bredt D S, Snyder S H, Yoshida, Y, Okamura T. Human uterine arterial relaxation induced by nitroxidergic nerve stimulation. Am. J. Physiol. 1994;266(4): H1446-H1450.
214(432)
Toda N, Kitamura T, Okamura T. Role of nitroxidergic nerve in dog retinal arterioles in vivo and arteries in vitro. Am. J. Physiol. 1994;266 (5): H1985-H1992.
215(437)
Okamura T, Yamazaki M, Toda N. Responses to histamine and acetylcholine in isolated monkey mesenteric veins versus arteries. Cardiovasc. Res. 1994;28(5): 667-672.
216(439)
Yoshida K, Okamura T, Toda N. Histological and functional studies on the nitroxidergic nerve innervating monkey cerebral, mesenteric and temporal arteries. Jpn. J. Pharmacol. 1994;65(4): 351-359.
217(442)
Okamura T, Toda N. Nitric oxide (NO)-mediated, vasodilator nerve function and its susceptibility to calcium antagonists. J. Auton. Nerv. Syst. 1994;49: S55-S58.
218(444)
Ayajiki K, Okamura T, Toda N. Neurogenic relaxations caused by nicotine in isolated cat middle cerebral arteries. J. Pharmacol. Exp. Ther. 1994;270(2): 795-801.
Okamura T, Toda N. Mechanism underlying nicotine-induced relaxation in dog saphenous arteries. Eur. J. Pharmacol. 1994;263(1-2): 85-91.
220(449)
Shiraishi S, Okamura T, Mori A Toda N. Differences in adrenergic nerve and receptor function in dog internal thoracic, coronary and mesenteric arteries. Jpn. J. Pharmacol. 1994;66(4): 481-488.
221(451)
Tanobe, Y., Fujimura, M. and Toda, N. Nitric oxide as a putative non-adrenergic, non-cholinergic neurotransmitter in dog duodenal muscles. Biomedical Res. 1995;15(2): 183-185.
222(455)
Yoshida. Y., Yoshida, K., Kimura, T. and Toda, N. Distribution of NADPH diaphorase-reactive nerves in the human female genital organ. Acta Obstet. Gynecol. Scand. 1995;74: 171-176.
223(456)
Okamura T, Yoshida K, Toda N. Nitroxidergic innervation in dog and monkey renal arteries. Hypertension. 1995;25(5): 1090-1095.
224(457)
Toda N, Yoshida K, Okamura T. Involvement of nitroxidergic and noradrenergic nerves in the relaxation of dog and monkey temporal veins. J. Cardiovasc. Pharmacol. 1995;25(5): 741-747.
225(458)
Kimura T, Okamura T, Yoshida Y, Toda N. Relaxant responses to prostaglandin F2a and E2 of isolated human uterine arteries. J. Cardiovasc. Pharmacol. 1995;26(2): 333-338. 226(459)
Toda N, Kitamura Y, Okamura T. Functional role of nerve-derived nitric oxide in isolated dog ophthalmic arteries. Invest. Ophthal. Vis. Sci. 1995;36(3): 563-570.
227(460)
Kitamura Y, Okamura T, Kani K, Toda N. Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries. J. Ocular Pharmacol. Ther. 1995;11(2): 167-176.
228(461)
Okamura T, Ide S, Toda N. Characteristics of DQ2511-induced relaxation in isolated dog, monkey and human arteries. Pharmacology. 1995;50(6): 370-379.
229(463)
Sai Y, Okamura T, Amakata Y, Toda N. Comparison of responses of canine pulmonary artery and vein to angiotensin II, bradykinin and vasopressin. Eur. J. Pharmacol. 1995;282(1-3): 235-241.
230(464)
Toda N, Zhang J-X, Ayajiki K, Okamura T. Mechanisms underlying endothelium-independent relaxation by acetylcholine in canine retinal and cerebral arteries. J. Pharmacol. Exp. Ther. 1995;274(3): 1507-1512.
Okamura T, Toda N. Comparison of the effect of dopamine in primate arteries and veins. Hypertens Res. 1995;18(Suppl.1): S35-S37.
232(469)
Morris, J.L., Gibbins, I.L., Kadowitz, P.J., Herzog, H., Kreulen, D.L., Toda, N. and Claing, A. Roles of peptides and other substances in cotransmission from vascular autonomic and sensory neurons. Can. J. Physiol. Pharmacol. 1995;73(5): 521-532.
233(470)
Okamura T, Uchiyama M, An J, Toda N. Nitric oxide-mediated neurogenic relaxation in monkey mesenteric veins. Jpn. J. Pharmacol. 1995;68(4): 405-411.
234(473)
Tanobe Y, Okamura T, Fujimura M, Toda N. Functional role and histoligical demonstration of nitric-oxide-mediated inhibitory nerves in dog sphincter of Oddi. Neurogastroenterol. Mot. 1995;7: 219-227.
235(475)
Toda N, Kimura T, Okamura T. Nitroxidergic nerve stimulation relaxes human uterine vein. J. Auton. Nerv. Syst. 1995; 55: 189-192.
236(476)
Okamura T, Kimura T, Toda N. Neurogenic vasodilation in canine uterine and iliac arteries. J. Hypertension. 1995;13(10): 1163-1168.
237(478)
Okamura T, Ayajiki K, Toda N. Basilar arterial constriction caused by intracisternal NG-nitro-L-arginine in anesthetized monkeys. Cardiovasc. Res. 1995;30(5): 663-667.
238(482)
Toda N, Uchiyama M, Okamura T. Prejunctional modulation of nitroxidergic nerve function in canine cerebral arteries. Brain Res. 1995;700(1-2): 213-218.
239(485)
An J, Okamura T, Mori A, Toda N. Canine pulmonary arterial and venous responses mediated by endothelin ETA and ETB receptors. Endothelium. 1996;4: 41-9.
240(486)
Hayashida H, Okamura T, Tomoyoshi T, Toda N. Neurogenic nitric oxide mediates relaxation of canine corpus cavernosum. J. Urology. 1996;155(3): 1122-1127.
241(489)
Toda N, Okamura T. Neurogenic nitric oxide (NO) in the regulation of cerebroarterial tone. J. Chem. Neuroanatomy. 1996;10(3-4): 259-265.
242(490)
Yoshida, K. and Toda, N. NADPH diaphorase-positive neurons in the intracardiac plexus of human, monkey and canine right atria. Brain Res. 1996;724(2): 256-259.
243(491)
Okamura T, Ayajiki K, Toda N. Neural mechanism of pressor action of nitric oxide synthase inhibitor in anesthetized monkeys. Hypertension. 1996;28(3): 341-346.
Toda N, Ayajiki K, Okamura T. Hypercapnia relaxes cerebral arteries and potentiates neurally-induced relaxation. J. Cerebral Blood Flow & Metab. 1996;16(5): 1068-1074.
245(493)
Zhang JX, Okamura T, Toda N. Pre- and postjunctional modulation by endothelin-1 of the adrenergic neurogenic response in canine mesenteric arteries. Eur. J. Pharmacol. 1996; 311(2-3): 169-176.
246(495)
Hayashida H, Fujimoto H, Yoshida K, Tomoyoshi T, Okamura T, Toda N. Comparison of neurogenic contraction and relaxation in canine corpus cavernosum and penile artery and vein. Jpn. J. Pharmacol. 1996;72(3): 231-240.
247(496)
Okamura T, Kitamura Y, Uchiyama M, Toda M, Ayajiki K, Toda N. Canine retinal arterial and arteriolar dilatation induced by nipradiol, a possible glaucoma therapeutic. Pharmacology. 1996;53(5): 302-310.
248(497)
Toda N, Toda M, Ayajiki K, Okamura T. Monkey central retinal artery is innervated by nitroxidergic vasodilator nerves. Invest. Ophthal. Vis. Sci. 1996;37(11): 2177-2184.
249(498)
Shiraishi S, Okamura T, Toda N. β1-Adrenoceptor-mediated relaxation by norepinephrine in dog hepatic arteries. Jpn. J. Pharmacol. 1997;73(1): 101-103.
250(499)
Yoshida, K. and Toda, N. Colocalization of acetylcholinesterase and vasoactive intestinal peptide (VIP) in nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) positive neurons in the intralingual ganglia and perivascular nerve fibers around lingual arteries in the porcine, monkey and canine tongue. Neurosci. Lett. 1997;222(3): 147-150.
251(500)
Okamura T, Zhang JX, Kangawa K, Toda N. Inhibition by adrenomedullin of the adrenergic neurogenic response in canine mesenteric arteries. Jpn. J. Pharmacol. 1997;73(3): 259-261.
252(501)
Toda N, Ayajiki K, Okamura T. Inhibition of nitroxidergic nerve function by neurogenic acetylcholine in monkey cerebral arteries. J. Physiol. 1997;498(2): 453-461.
253(504)
Uchiyama M, Okamura T, Uehara M, Toda N. Analysis of the vasodilator nerve function by nicotine in isolated dog skin artery. Eur. J. Pharmacol. 1997;321(1): 19-25.
254(505)
Okamura T, Ayajiki K, Kangawa K, Toda N. Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries. Invest. Ophthal. Vis. Sci. 1997;38 (1): 56-61. 255(506)
Toda N, Ayajiki K, Uchiyama M, Okamura T. Nitric oxide-mediated neurogenic vasodilatation in isolated monkey lingual arteries. Am. J. Physiol. 1997;272(Heart Circ. Physiol. 4pt2) : H1582-H1588.
Zhang J X, Okamura T, Toda N. Prejunctional regulation by endogenous and exogenous aceytylcholine of adrenergic nerve function in isolated canine mesenteric arteries. Hypertens Res. 1997;20(2): 119-125.
257(508)
Ayajiki K, Okamura T, Toda N. Flunarizine, an anti-migraine agent, impairs nitroxidergic nerve function in cerebral arteries. Eur. J. Pharmacol. 1997;329(1): 49-53.
258(509)
Okamura T, Ayajiki K, Toda N. Hypoxia-induced inhibition of the response to nitroxidergic nerve stimulation in canine cerebral arteries. J. Cerebral Blood Flow & Metab. 1997; 17(7): 807-813.
259(510)
Ayajiki K, Hayashida H, Okamura T, Toda N. Pelvic nerve stimulation-induced pressor responses in corpus cavernosum of anesthetized dogs. Am. J. Physiol. 1997;273(5pt2): H2141-2145.
260(511)
Toda M, Okamura T, Azuma I, Toda N. Modulation by neurogenic acetylcholine of nitroxidergic nerve function in porcine ciliary arteries. Invest. Ophthal. Vis. Sci. 1997;38 (11): 2261-2269.
261(512)
Okamura T, Toda M, Ayajiki K, Toda N. Receptor subtypes involved in relaxation and contraction by arginine vasopressin in canine isolated short posterior ciliary arteries. J. Vasc. Res. 1997;34 (6): 464-472.
262(514)
Toda N, Ayajiki K, Okamura T. Effect of Ca2+/calmodulin-dependent protein kinase II inhibitors on the neurogenic cerebroarterial relaxation. Eur. J. Pharmacol. 1997;340(1): 59-65. 263(516)
Sai Y, Ayajiki K, Okamura T, Nosaka S, Toda N. Comparison of the effects of pancuronium and vecuronium in canine coronary and renal arteries. Anesthesiology. 1998;88(1): 165-171.
264(517)
Shiraishi S, Okamura T, Kodama M, Toda N. Mechanisms underlying the neurogenic relaxation in dog isolated hepatic arteries. J. Cardiovasc. Pharmacol. 1998;31(3): 372-376. 265(518)
Toda N, Okamura T. Cerebral vasodilators. Jpn. J. Pharmacol. 1998;76(3): 349-367. 266(519)
Toda M, Ayajiki K, Okamura T, Azuma I, Toda N. Desmopressin-induced dog ciliary artery relaxation. Eur. J. Pharmacol. 1998;344(2-3):197-201.
267(520)
Okamura T, Ayajiki K, Toda N. Monkey corpus cavernosum relaxation mediated by NO and other relaxing factor derived from nerves. Am. J. Physiol. 1998;274(4Pt2): H1075-1081.
Toda N, Toda M, Ayajiki K, Okamura T. Cholinergic nerve function in monkey ciliary arteries innervated by nitroxidergic nerve. Am. J. Physiol. 1998;274(5Pt2): H1582-1589. 269(525)
Okamura T, Fujioka H, Ayajiki K, Toda N. Modifications by superoxide-generating agent, neurotransmitters and neuromodulators of nitroxidergic nerve function in monkey cerebral arteries. J. Pharmacol. Exp. Ther. 1998;286(3): 1321-1325.
270(526)
Okamura T, Ayajiki K, Uchiyama M, Kagami K, Toda N. Mechanisms underlying constrictor and dilator responses to perivascular nerve stimulation in canine lingual arteries. Eur. J. Pharmacol. 1998;354 (1): 43-50.
271(528)
Ayajiki K, Okamura T, Fujioka H, Nakayama K, Tsuji K, Toda N. Functional Studies on Blockade by Neosurugatoxin of Nicotinic Receptors in Nitroxidergic and Sensory Nerve Terminals and Intramural Ganglionic Cells. Jpn. J. Pharmacol. 1998;78(2): 217-223.
272(529)
Okamura T, Tanobe Y, Fujioka H, Ayajiki K, Toda N. Mechanism of neurogenic relaxation and modification of the response by enteric substances in isolated dog colon. Eur. J. Pharmacol. 1998;358 (3): 245-252.
273(530)
Tanaka T, Okamura T, Handa J, Toda N. Neurogenic vasodilation mediated by nitric oxide in porcine cerebral arteries. J. Cardiovasc. Pharmacol. 1999;33 (1): 56-64.
274(531)
Okamura T, Ayajiki K, Uchiyama M, Uehara M, Toda N. Neurogenic vasodilatation of canine isolated small labial arteries. J. Pharmacol. Exp. Ther. 1999;288(3) :1031-1036.
275(533)
Ayajiki K, Hayashida H, Okamura T, Toda N. Influence of denervation on neurogenic inhibitory response of corpus cavernosum and nitric oxide synthase histochemistry. Brain Res. 1999;825 (1-2) : 14-21.
276(535)
Okamura T, Ayajiki K, Fujioka H, Toda N. Mechanisms underlying arginine vasopressin-induced relaxation in monkey isolated coronary arteries. J. Hypertension. 1999;17(5): 673-678.
277(536)
Toda M, Okamura T, Fujimiya M, Azuma I, Toda N. Mechanism s underlying the neurogenic relaxation of isolated porcine sphincter Pupillae. Exp. Eye. Res. 1999;68(4) : 505-512.
278(537)
Okamura T, Ayajiki K, Fujioka H, Toda M, Fujimiya M, Toda N. Effects of endothelial impairment by saponin on the responses to vasodilators andnitrergic nerve stimulation in isolated canine corpus cavernosum. Br. J. Pharmacol. 1999;127 (3): 802-808.
Toda M, Okamura T, Ayajiki K, Toda N. Neurogenic vasoconstriction as affected by cholinergic and nitroxidergic nerves in dog ciliary and ophthalmic arteries. Invest. Ophthal. Vis. Sci. 1999;40 (8) : 1753-1760.
280(544)
Ayajiki K, Okamura T, Fujioka H, Imaoka S, Funae Y, Toda N. Involvement of CYP3A-derived arachidonic acid metabolite(s) in responses to endothelium-derived K+ channel opening substance in monkey lingual artery. Br. J. Pharmacol. 1999;128 (3): 802-808.
281(548)
Fujioka H , Okamura T , Toda T. Inhibition by adrenomedullin of amine release from adrenergic nerves in dog mesenteric arteries. Eur. J. Pharmacol. 1999;358(2-3):155-161.
282(551)
Kashiwagi A, Shinozaki K, Nishio Y, Okamura T, Toda N, Kikkawa R. Free radical production in endothelial cells as a pathogenetic factor for vascular dysfunction in the insulin resistance state. Diabetes Res. Clin. Prac. 1999;45 : 199-203.
283(552)
Shinozaki K, Kashiwagi A, Nishio Y, Okamura T, Yoshida Y, Masada M, Toda N, Kikkawa R. Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta. Diabetes. 1999;48(12):2437-2445.
284(553)
Toda N, Ayajiki K, Tanaka T, Okamura T. Preganglionic and postganglionic neurons responsible for cerebral vasodilation mediated by nitric oxide in anesthetized dogs. J. Cerebral Blood Flow & Metab. 2000;20(4): 700-708.
285(554)
Shinozaki K, Okamura T, Nishio Y, Kashiwagi A, Kikkawa R, Toda N. Evaluation of endothelial free radical release by vascular tension responses in insulin-resistant rat aorta. Eur. J. Pharmacol. 2000;394(2-3):295-299.
286(555)
Toda N, Tanaka T, Ayajiki K, Okamura T. Cerebral vasodilatation induced by stimulation of the pterygopalatine ganglion and greater petrosal nerve in anesthetized monkeys. Neuroscience. 2000;96(2): 393-398.
287(557)
Shinozaki K, Nishio Y, Okamura T, Yoshida Y, Maegawa H, Kojima H, Masada M, Toda N, Kikkawa R, Kashiwagi A. Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats. Circ. Res. 2000;87(7): 566-573.
288(559)
Okamura T, Ghoneim HA, Ayajiki K, Ammar ES, Toda N. Mechanisms underlying contraction and relaxation induced by nerve stimulation in monkey uterine arteries. Pharmacology. 2000;61(4): 251-256.
289(560)
Ayajiki K, Tanaka T, Okamura T, Toda N. Evidence for nitroxidergic innervation in monkey ophthalmic arteries in vivo and in vitro. Am J Physiol Heart Circ Physiol. 2000;279(4):H2006-H2012.
Ayajiki K, Ozaki M, Shiomi M, Okamura T, Toda N. Comparison of endothelium-dependent relaxation in carotid arteries from Japanese white and Watanabe heritable hyperlipidemic rabbits. J. Cardiovasc. Pharmacol. 2000;36(5): 662-630.
291(562)
Ayajiki K, Fujioka H, Okamura T. Mechanisms underlying endothelium-dependent, nitric oxide/prostacyclin-independent, acetylcholine-induced relaxation in canine corpus cavernosum. Naunyn-Schmiedeberg’s Arch. Pharmacol. 2000;362(4-5): 448-451.
292(564)
Okamura T, Ayajiki K, Toda N. Hypothermia on NO-mediated neurogenic relaxation and on hypoxic inhibition in the response of canine cerebral arteries. Hypertens Res. 2001;24(1): 47-53.
293(565)
Toda N, Ayajiki K,Fujioka H, Okamura T. Ginsenoside potentiate NO-mediated neurogenic vasodilation of monkey cerebral Arteries. J. Ethnopharmacol. 2001; 76(1): 109-113. 294(566)
Ayajiki K, Fujioka H, Noda K, Okamura T, Toda N. Modifications by sumatriptan and acetylcholine of nitric oxide-mediated neurogenic dilatation in dog cerebral arteries. Eur. J. Pharmacol. 2001;420(1):67-72.
295(567)
Kimura T, Toda N, Noda Y, Okamura T,. Mechanisms of relaxation induced by angiotensin II in isolated canine and human uterine arteries. J. Cardiovasc. Pharmacol. 2001;37(5): 585-595.
296(568)
Ayajili K, Fujioka H, Okamura T, Toda N,. Relatively selective neuronal nitric oxide synthase inhibition by 7-nitroindazole in monky isolated cerebral arteries. Eur. J. Pharmacol. 2001;423(2-3):179-183.
297(571)
Okamura T, Fujioka H, Ayajiki K. Effects of calcium antagonists on the nitrergic nerve function in canine corpus cavernosum. Jpn. J. Pharmacol. 2001;87(3): 208-213.
298(572)
Shinozaki K, Hirayama A, Nishio Y, Yoshida Y, Ohtani T, Okamura T, Masada M, Kikkawa R, Kodama K, Kashiwagi A. Coronary endothelial dysfunction in the insulin-resistant state is linked to abnormal pteridine metabolism and vascular oxidative stress. J. Am. Coll. Cardiol. 2001;38(7):1821-1828.
299(573)
Takeuchi E, Kitano H, Fujioka H, Toda N, Kitajima K, and Okamura T. Nitric oxide synthase activity in human thyroid papillary carcinomas. Acta Histochem.Cytochem. 2001;34(3):207-212.
300(575)
Okamura T, Ayajiki K, Fujioka H, Shinozaki K, Toda N. Neurogenic cerebral vasodilation mediated by nitric oxide. Jpn. J. Pharmacol. 2002;88(1): 32-38.
Okamura T, Fujioka H, Ayajiki K. Effects of nipradilol on α-adrenoceptor function in ocular arteries. Pharmacology. 2002;65 (2):110-118.
302(579)
Kimura T, Ayajiki K, Noda Y, and Okamura T. Comparison of the responses to thrombin in monkey renal and uterine arteries. J Soc Gynecol Investig. 2002; 9(3):145-151. 303(580)
Ayajiki K, Okamura T, Noda K, and Toda N. Functional study on nitroxidergic nerve in isolated dog pulmonary arteries and veins. Jpn. J. Pharmacol. 2002;89(2):197-200.
304(582)
Fujioka H, Ayajiki K, Shinozaki K, Toda N, Okamura T. Mechanisms underlying endothelium-dependent, nitric oxide- and prostanoid-independent relaxation in monkey and dog coronary arteries. Naunyn-Schmiedeberg’s Arch. Pharmacol. 2002;366(5):488-495.
305(583)
Ayajiki K, Fujioka H, Torii R, Toda N, Okamura T. Endothelial and neuronal functions in cerebral and temporal arteries from monkeys fed a high-cholesterol diet. J. Cardiovasc. Pharmacol. 2002;40(3):456-466.
306(588)
Ayajiki K, Fujioka H, Toda N, Okada S, Minamiyama Y, Imaoka S, Funae Y, Watanabe S, Nakamura A, and Okamura T. Mediation of arachidonic acid metabolite(s) produced by endothelial cytochrome P-450 3A4 in monkey arterial relaxation. Hypertens Res. 2003;26(3): 237-243.
307(589)
Tanaka T, Ayajiki K, Fujioka H, Toda N, Okamura T. Protection by hypothermia of hypoxia-induced inhibition of neurogenic vasodilation in porcine cerebral arteries. J Pharmacol Sci. 2003;92(2):93-99.
308(596)
Fujioka H, Ayajiki K, Shinozaki K, Okamura T. Mechanisms underlying endothelium-dependent flow increase in perfused rat mesenteric vascular bed. Eur. J. Pharmacol. 2004;485(1-3):219-25.
309(597)
Shinozaki K, Ayajiki K, Nishio Y, Sugaya T, Kashiwagi A, Okamura T. Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance. Hypertension. 2004;43(2):255-262.
310(604)
Yarnitsky D, Gross Y, Lorian A, Shalev A, Shorer S, Tanaka T, Ayajiki K, Fujimiya M, Okamura T. Increased BBB permeability by parasympathetic sphenopalatine ganglion stimulation in dogs. Brain Res. 2004;1018(2):236-40.
311(606)
Shinozaki K, Ayajiki K, Kashiwagi A, Masada M, Okamura T. Malfunction of vascular control in lifestyle-related diseases: mechanisms underlying endothelial dysfunction in the insulin-resistant state. J Pharmacol Sci. 2004;96(4): 401-405.
Ayajiki K, Fujioka H, Shinozaki K, Okamura T. Effects of capsaicin and nitric oxide synthase inhibitor on increase in cerebral blood flow induced by sensory and parasympathetic nerve stimulation in the rat. J Appl Physiol. 2005;98(5):1792-1798.
313(613)
Shinozaki K, Nishio Y, Yoshida Y, Koya D, Ayajiki K, Masada M, Kashiwagi A, Okamura T. Supplement of tetrahydrobiopterin by a gene transfer of GTP cyclohydrolase I cDNA improves vascular dysfunction in insulin-resistant rats. J. Cardiovasc. Pharmacol. 2005;46(4):505-12.
314(619)
Yamamizu K, Shinozaki K, Ayajiki K,Gemba M, Okamura T. Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure. J. Cardiovasc. Pharmacol. 2007;49(3):131-9.2007.
315(620)
Shinozaki K, Nishio Y, Ayajiki K, Yoshida Y, Masada M, Kashiwagi A, Okamura T. Pitavastatin restores vascular dysfunction in insulin-resistant state by inhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxide synthase-dependent superoxide production. J. Cardiovasc. Pharmacol. 2007;49(3):122-130.
316(623)
Ayajiki K, Kimura T, Yamamizu K, Okamura T. Mechanisms underlying mechanical responses to ephedra herb of isolated rabbit urinary bladder and urethra, a possible stress urinary incontinence therapeutic. J Pharmacol Sci. 2008;107 (2): pp. 175-180.
317(625)
Ayajiki K, Ozaki Y, Wang C, Okamura T. Cilostazol's effect on the response to perivascular nerve stimulation in isolated dog cerebral and mesenteric arteries. Hypertens Res. 2008;31 (7) : 1425-1433.
318(630)
Ayajiki K, Hayashida H, Tawa M, Okamura T, Toda N. Characterization of nitrergic function in monkey penile erection in vivo and in vitro. Hypertens Res. 2009; 32(8):685-9. 319(634)
Ayman Geddawy , Shimosato T, Tawa M, Imamura T, Okamura T. Comparison of endothelium-related responses to nucleotides of dog and monkey cerebral arteries. J Pharmacol Sci. 2010;112(3):378-81.
320(635)
Ogawa F, Hanamitsu M, Ayajiki K, Aimi Y, Okamura T, Shimizu T. Effect of nitric oxide synthase inhibitor on increase in nasal mucosal blood flow induced by sensory and parasympathetic nerve stimulation in rats. Annals of otology rhinology and laryngology. 2010;119(6): 424-430.
321(636)
Tawa M, Fukumoto T, Yamashita N, Ohkita M, Ayajiki K, Okamura T, Matsumura Y. Postconditioning improves postischemic cardiac dysfunction independently of norepinephrine overflow after reperfusion in rat hearts: comparison with preconditioning. J. Cardiovasc. Pharmacol. 2010;55(1):6-13. 2010.
Ayman Geddawy, Shimosato T, Tawa M, Imamura T, and Okamura T. Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. J. Pharmacol Sci. 2010;114(2)： pp. 180-188.
323(641)
Oh da Y, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 2010; 3;142(5):687-98.
324(642)
Tawa M, Fukumoto T, Ohkita M, Yamashita N, Geddawy A, Imamura T, Ayajiki K, Okamura T, Matsumura Y. Effects of exogenous big endothelin-1 on post-ischemic cardiac dysfunction and norepinephrine overflow in rat hearts. Hypertens Res. 2011;34(2):218-24. 325(643)
Tawa M, Yamamizu K, Geddawy A, Shimosato T, Imamura T, Ayajiki K, Okamura T. Impairment by hypoxia or hypoxia/reoxygenation of nitric oxide-mediated relaxation in isolated monkey coronary artery: the role of intracellular superoxide. J Pharmacol Sci. 2011;116(2):188-96. 2011.
326(644)
Tawa M, Fukumoto T, Ohkita M, Yamashita N, Geddawy A, Imamura T, Ayajiki K, Okamura T, Matsumura Y. Contribution of nitric oxide in big endothelin-1-induced cardioprotective effects on ischemia/reperfusion injury in rat hearts. J. Cardiovasc. Pharmacol. 2011;57(5):575-8.
327(645)
Ayajiki K, Kobuchi S, Tawa M, Okamura T. Nitrergic nerves derived from the pterygopalatine ganglion innervate arteries irrigating the cerebrum but not the cerebellum and brain stem in monkeys. Hypertens Res. 2012;35(1):88-92.
328(647)
Shimosato T, Geddawy A, Tawa M, Imamura T, Okamura T. Chronic Administration of Nicotine-Free Cigarette Smoke Extract Impaired Endothelium-Dependent Vascular Relaxation in Rats via Increased Vascular Oxidative Stress. J Pharmacol Sci. 2012;118(2):206-14.
329(648)
Fukumoto T, Tawa M, Kitada K, Yamashita N, Ohkita M, Okamura T, Matsumura Y. Different effects of AT1 receptor antagonist and ET(A) receptor antagonist on ischemia-induced norepinephrine release in rat hearts. J Cardiovasc Pharmacol. 2012;60(1):55-60.
330(651)
Kimura I, Ozawa K, Inoue D, Imamura T, Kimura K, Maeda T, Terasawa K, Kashihara D, Hirano K, Tani T, Takahashi T, Miyauchi S, Shioi G, Inoue H, Tsujimoto G. The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun. 2013;4:1829(-40).
331(652)
Tawa M, Shimosato T, Geddawy A, Imamura T, Okamura T. Influence of Hypoxia on Endothelium-Derived NO-Mediated Relaxation in Rat Carotid, Mesenteric and Iliac Arteries. Pharmacology. 2013;91(5-6):322-330.
Okamura T, Tawa M, Geddawy A, Shimosato T, Iwasaki H, Shintaku H, Yoshida Y, Masada M, Shinozaki K, Imamura T. Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats. J Pharmacol Sci. 2014;124(1):76-85.
333(657)
Tawa M, Geddawy A, Shimosato T, Iwasaki H, Imamura T, Okamura T. Soluble guanylate cyclase redox state under hypoxia or hypoxia/reoxygenation in isolated monkey coronary arteries. J Pharmacol Sci. 2014;125(2):169-75.
総説
1(275)
Toda, N. Is histamine a human coronary vasospastic substance?. Trends Pharmacol. Sci. 1987;8: 289-290.
2(301)
Toda, N. Beraprost sodium. Cardiovasc. Drug Rev. 1988;6(3): 222-238. 3(383)
Toda N, Okamura T. Regulation by nitroxidergic nerve of arterial tone. News Physiol. Sci. 1992;7: 148-152.
4(404)
Toda N, Okamura T. Cerebral vasoconstrictor mediators. Pharmacol Ther. 1993;57(213): 359-375.
5(462)
Toda. N. Nitroxidergic nerves and hypertension. Hypertens Res. 1995;18(1): 19-26. 6(477)
Toda, N. Regulation of blood pressure by nitroxidergic nerve. J. Diabetes and Its Complicat. 1995; 9(4): 200-202.
7(488)
Toda N, Okamura T. Nitroxidergic nerve: regulation of vascular tone and blood flow in the brain. J. Hypertension. 1996;14(4): 423-434.
8(584)
Shinozaki K, Kashiwagi A, Masada M, and Okamura T. Stress and vascular responses: oxidative stress and endothelial dysfunction in the insulin-resistant state. J Pharmacol Sci. 2003;91(3):187-191.
9(590)
Toda N, Okamura T. The pharmacology of nitric oxide in the peripheral nervous system of blood vessels. Pharmacol Rev. 2003;55(2):271-324.
10(594)
Shinozaki K, Kashiwagi A, Masada M, Okamura T. Molecular mechanisms of endothelial dysfunction in the insulin-resistant state: the roles of abnormal pteridine metabolism. Pteridines. 2003;14(1):13-16.
11(599)
Shinozaki K, Kashiwagi A, Masada M, and Okamura T. Molecular mechanisms of impaired endothelial function associated with insulin resistance. Curr Drug Targets Cardiovasc Haematol Disord. 2004;4(1):1-11.
12(609)
Toda N, Ayajiki K, Okamura T. Nitric oxide and penile erectile function. Pharmacol Ther. 2005;106(2):233-266.
13(614)
Shinozaki K, Kashiwagi A, Masada M, Okamura T. Tetrahydrobiopterin and endothelial dysfunction in cardiovascular diseases. Pteridines. 2006;17(1):11-15.
Toda N, Ayajiki K. Phylogenesis of constitutively formed nitric oxide in non-mammals. Rev Physiol Biochem Pharmacol. 2006;157:31-80.
15(618)
Toda N, Ayajiki K, Okamura T. Interaction of endothelial nitric oxide and angiotensin in the circulation. Pharmacol Rev. 2007;59(1):54-87.
16(628)
Ayajiki K, Tamayama T, Shinozaki K , Okamura T. Nitrergic control of cerebral vascular tone and blood flow, and a possible blood-brain barrier function. Tzu Chi Medical Journal. 2009;21(1):1-5.
17(629)
Toda N, Ayajiki K, Okamura T. Cerebral blood flow regulation by nitric oxide: recent advances. Pharmacol Rev. 2009;61(1):62-97.
18(631)
Toda N, Ayajiki K, Okamura T. Control of systemic and pulmonary blood pressure by nitric oxide formed through neuronal nitric oxide synthase. J Hypertens. 2009;27(10):1929-40. 19(632)
Toda N, Ayajiki K, Okamura T. Cerebral blood flow regulation by nitric oxide in neurological disorders. Can. J. Physiol. Pharmacol. 2009;87(8):581-94.
20(637)
Toda N, Okamura T. Modulation of renal blood flow and vascular tone by neuronal nitric oxide synthase-derived nitric oxide. J Vasc Res. 2010; 48(1): 1-10.
21(638)
Toda N, Imamura T, Okamura T. Alteration of nitric oxide-mediated blood flow regulation in diabetes mellitus. Pharmacol Ther. 2010;127(3):189-209.
22(649)
Toda N, Ayajiki K, Okamura T. Neurogenic and endothelial nitric oxide regulates blood circulation in lingual and other oral tissues. J. Cardiovasc. Pharmacol. 2012;60(1):100-8. 23(650)
Toda N, Okamura T. Cerebral blood flow regulation by nitric oxide in Alzheimer's disease. J Alzheimers Dis. 2012;32(3):569-78.
24(653)
Toda N, Toda H, Okamura T. Regulation of myometrial circulation and uterine vascular tone by constitutive nitric oxide. Eur J Pharmacol. 2013;714(1-3):414-23.
25(655)
Toda N, Okamura T. Obesity impairs vasodilatation and blood flow increase mediated by endothelial nitric oxide: An overview. J Clin Pharmacol. 2013;53(12):1228-39.
著書
1(114)
Toda, N. Responses of isolated cerebral and peripheral arteries to vasoconstricting agents. Neurogenic Control of Brain Circulation. Proceedings of International Symposium Wenner-Green Vol.30. 1977;pp. 207-215.
2(124)
Toda, N. Heterogeneity in the relaxation of vascular smooth muscle. Mechanisms of Vasodilatation. 1978;pp. 129-136.
3(133)
Toda, N. Dopamine-induced Relaxation of Isolated Dog Arteries. Peripheral Dopaminergic Receptors. Advances in the Bioscience, Vol.20. 1979;pp. 135-141.
4(154)
Ohta, T., Kajikawa, H., Yoshikawa, Y., Shimizu, K., Funatsu, N., Yamamoto, M. and Toda, N. Cerebral vasospasm and hemoglobins: Clinical and experimental studies. Cerebral Arterial Spasm. 1980;pp. 166-172.
5(174)
Toda, N. Mechanism of vascular smooth muscle relaxation induced by angiotensins. Vasodilatation. 1981;pp. 151-157.
6(206)
Toda, N. Non-adrenergic innervation in vascular smooth muscle. Vascular Neuroeffector Mechanisms: 4th International Symposium. 1983;pp. 57-62.
7(224)
Toda, N. Prostaglandin and Blood Vessel Function. Regulation of Cardiac Function. 1984;pp. 253-260.
8(242)
Toda, N., Nakajima, M. and Miyazaki, M. Neuroeffector actions of prostaglandins on isolated arteries. Advances in Prostaglandin, Thromboxane, and Leukotriene Research, Vol. 15. 1985;pp. 495-497.
9(288)
Toda, N. Heterogenous responses to histamine in blood vessels. Vasodilatation. 1988;pp. 531-535.
10(293)
Toda, N. Functional characteristics of human coronary arteries. Pharmacology in Developing Countries. 1988;pp. 44-50.
11(319)
Okamura T, Toda N. Different involvement of endothelium-derived relaxing factor and prostacyclin in vasodilator response to bradykinin in isolated dog blood vessels. Kinins V, Part A. 1989;pp. 429-34.
12(320)
Okunishi, H., Spragg, J., Burton, J. and Toda, N. In vivo inhibition of tissue kallikreins by kininogen sequence analogue peptides. Kinins V, Part B. 1989;pp. 23-28.
