第25回日本時間生物学会学術大会　抄録集 ……………………………………………………………………………………………………………133

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169

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2018

10

20

21

2

2017

From the Discovery to Innovations

the Discovery

Serge Daan

2006

6

10

19

20 Years since Discovery of Mammalian Clock

Genes

Plenary Lecture

Gene Block

PI

PI Global

Session

Landmark Lecture

Mammalian Clock Genes Cloned in Japan

10

20

7

25

時間生物学 Vol. 24, No. 2 (2018) 1 4

時間生物学 Vol. 24, No. 2 (2018)

時間生物学 Vol. 24, No. 2 (2018) 1

時間生物学 Vol. 24, No. 2 (2018)

時間生物学 Vol. 24, No. 2 (2018) 1 8

時間生物学 Vol. 24, No. 2 (2018)

時間生物学 Vol. 24, No. 2 (2018) 140

時間生物学 Vol. 24, No. 2 (2018)

時間生物学 Vol. 24, No. 2 (2018) 14

時間生物学 Vol. 24, No. 2 (2018) 14

25

S1-1 Problem of adjustment of individual circadian rhythm to social time in school students

S1-2 Alignment of clocks: Social jetlag and work productivity

S1-3 The costs of flexible work schedule and its impact on employees

1, 2 1 ; 2 S1-4 時間生物学 Vol. 24, No. 2 (2018) 14

8:30 ~ 10:20 S2

S2-1 Regulation of bone and cartilage metabolism and molecular clock

S2-2 Identification of brainstem REM/non-REM sleep regulating neurons and insights to the function of REM sleep

WPI-IIIS

S2-3 Adrenergic control of diurnal rhythms in the immune system

S2-4 Molecular clocks and circadian rhythms in mammals

10:30 ~ 11:50

時間生物学 Vol. 24, No. 2 (2018) 14

12:00 ~ 12:50 MSD WPI-IIIS 13:00 ~ 13:55 14:00 ~ 14:50 F F 15:00 ~ 16:50 S

S3-1 Key note lecture Chrono-nutrition from mouse to human health

~ ~

S3-2 Research on human circadian characteristics based on peripheral clock gene expression

1 2

1 ; 2

S3-3 Prevention of progression of chronic kidney disease: Elucidation of daily oscillation of plasma inorganic phosphate concentration

:

1,2 3 3 3

1 ; 2

時間生物学 Vol. 24, No. 2 (2018)

; 3

S3-4 Development of novel breast cancer treatment based on molecular clock machinery

1,2 2

1 ; 2

15:00 ~ 16:50 S

24

S4-1 Chronobiology based on amplitude

S4-2 A small molecule reveals novel post-translational regulation of plant circadian clock

1,2

1 ; 2

S4-3 Diversity and universality of insect clocks

S4-4 Mechanism of synchronized Hes7 oscillations in the somite segmentation clock Hes7

時間生物学 Vol. 24, No. 2 (2018) 149

17:00 ~ 18:00 ) 19:00 ~ 21:00 <10 21 > 8:30 ~ 9:25 9:30 ~ 10:20 10:30 ~ 11:15 I Benzer

per

KLF transcription family plays key roles in the pathogenesis of complex disease

12:10 ~ 12:55

Serge Daan:

時間生物学 Vol. 24, No. 2 (2018)

13:00 ~ 14:50 S5

Epoch-making Discoveries in Chronobiology

2017

5

S5-1 Cleaning Drosophila’s Clock: Unaddressed and Unresolved Questions about the Fruit Fly Circadian Timekeeper

S5-2

A-B

S5-3 What do we know about circadian clocks: a Drosophila perspective Emi Nagoshi

Department of Genetics and Evolution, University of Geneva, Geneva, Switzerland S5-4 Critical review and perspective of sleep research using Drosophila

Department of Genetics and Evolution, University of Geneva, Geneva, Switzerland

時間生物学 Vol. 24, No. 2 (2018) 1 1

13:00 ~ 14:50 S6

Origin of Circadian Rhythm

S6-1 Emergence of Circadian Clock Oscillation in Mammals

S6-2 Deep-sea Hydrothermal Field: Ecosystem Isolated from Day-night Cycle Ryuhei Nakamura1,2_{, Shawn Mcglynn}1

1 (ELSI); 2 (CSRS)

S6-3 Circadian redox rhythm in photosynthetic cyanobacterial cells

1 ; 2

S6-4 Seeking for evolutionary origins of 24h-periodicity in the cyanobacterial circadian clock 24

1,2 1,2 1,2

1 ; 2 SOKENDAI

S6-5 Structure-guided engineering of mammalian Cryptochrome to elucidate the origin of 24-hour period

24

15:00 ~ 16:00

時間生物学 Vol. 24, No. 2 (2018)

P 001 P 0 8 P 0 9 P 106

10 20 1 00 1 0

10 21 09 0 10 20

P001 Relationships among clock genes expression rhythms sleep and meal conditions in delayed sleep phase syndrome or night eating syndrome

P002

P00 iurnal preferences and social etlag but not chronotypes are directly associated with psychological distress

P00 Effect of periocular cutaneous warming before bedtime on sleep status periphery cutaneous temperature and performance on the following day

P00 leep and psychiatric problems among university students classified into evening and intermediate chronotype

時間生物学 Vol. 24, No. 2 (2018) 1

P006 b ective and sub ective physical activity levels in relation to chronotypes in elderly individuals cross-sectional analysis in the E -KY cohort

P007 Chronotypes light exposure and sleep disturbances in elderly individuals cross-sectional analysis in the E -KY cohort

P008 Effect of seasonal changes in circadian rhythm on glucose metabolism under normal living condition in healthy young sub ects

P009 Relationship of ob ectively-evaluated chronotype to morning moods and physical symptoms in office workers

P010 leep habits of apanese infants and their parents

P011 Effects of sleep-wake rhythm according to natural light-dark cycle on melatonin secretion in children

時間生物学 Vol. 24, No. 2 (2018)

P012 Relationship between problems with childcare and meal habit chronotype

P01

P01 B F

P01 Relationship between time of day to feel stress and chronotype problems in physical and mental conditions in apanese infants aged -6 years old

P016 CL CK

P017 A new insight of tooth development

hether do incremental lines in dentin really have circadian rhythm

P018 Maintenance of time-dependent spatial memory by neurosteroids in mice

時間生物学 Vol. 24, No. 2 (2018) 1

P019 Effect on body weight change by high-fat diet feeding according to the variation in tide-generating force

P020 Modulation of neurogenesis by photoperiod in mice

P021 Regulation of energy metabolism in peripheral tissues by light exposure

P022 Circadian rhythm of salivary cortisol is associated with the PA axis activity in response to acute psychological stress in healthy sub ects

P02 evelopmental photoperiod alters A methyltransferase expression in mice A

P02 he effect of seasonal cues on photoreceptor gene expression in mouse eye

P02 Circadian scaffolding function of ERF1 for plasmalemmal expression of xenobiotic transporter in mouse liver

時間生物学 Vol. 24, No. 2 (2018)

P026 Analysis of the synchroni ation of individual circadian rhythms in marmosets

P027 Efficient method for food-induced phase shift of circadian activity rhythms in mice

P028 Effects of the isolation of suprachiasmatic nucleus on rhythms of neuronal firing activity in the brain

P029 Analysis of the central circadian clock in A P neuron specific vesicular ABA transporter deficient mice

A P ABA

P0 0 Circadian rhythms of triglyceride accumulation in adipocytes

P0 1 ifferences in the circadian phenotype among substrains of CBA mice CBA

P0 2 Altered circadian rhythms in secretin receptor deficient mice

時間生物学 Vol. 24, No. 2 (2018) 1

P0 CaMK

P0 Controlling cellular clocks by P- PAC2 signaling P- PAC2

P0 -California mouse Free runner

P0 6 Effect of aily Light on c-Fos Expression in the uprachiasmatic ucleus under et Lag Conditions C c-Fos

P0 7 Photoactivation of circadian rhythms in the C using spaciotemporal novel Light- ated lutamate Receptor ystem

Light- ated lutamate Receptor C

P0 8 ipr2 receptors in the thalamus and the effect of retinal innervation ipr2

P0 9 Corticotrophin releasing factor neurons in the paraventricular nucleus in the hypothalamus promote wakefulness in mice

Ⅱ

時間生物学 Vol. 24, No. 2 (2018)

P0 0 estosterone replacement exacerbates the age-related decline in circadian rhythmicity

P0 1 Molecular clock-based analysis for mechanisms of E F induction in ischemic retina E F

P0 2 he effect of breakfast skipping on circadian body temperature rhythms in mice

P0 Fast fluorescent imaging reveals the mechanism of circadian calcium rhythm generation in suprachiasmatic neurons

Ca2

P0 nsulin secretion synchroni ed with activity rhythms is important for regulation of skeletal muscle mass in mice

P0 nderstanding a homeostatic regulatory system through K in the neuro-glial network K

時間生物学 Vol. 24, No. 2 (2018) 1 9

P0 6 Effect of intake time of fish oil ( A and EPA) on serum lipids or gene expression in healthy adults A EPA

P0 7 Effect of exercise timing on mouse intestinal microflora under inulin feeding

P0 8 ime-restricted feeding of a high-fat diet affects aging on senescence-accelerated mouse

P0 9 Polymethoxyflavones in black ginger (kaempferia parviflora) extract upregulate the expression of circadian clock genes and enhance lipolysis

(kaempferia parviflora)

P0 0

P0 1 Chronic advance shifts increase mortality in APCmin_mice

APCmin

P0 2 Effect of desynchroni ation on hypoglycemic response of an antidiabetic drug in rats

時間生物学 Vol. 24, No. 2 (2018)

P0 Analysis of social entrainment in California mouse (Peromyscus californicus)

P0 Pineal humoral factors suppress striatal glutamate signal transduction to avoid autism-like mental disorder in mice

P0 Bmal1 p21

P0 6 asopressin signal inhibition in aged mice increases survival rate under chronic et lag

P0 7 Period knockout phenotype in human cell line suggests its non-human-specific role in circadian clock Period

P0 8 mmunohistological distribution of Calcitonin receptor in the brain here is a mediator of body temperature rhythm

P0 9 CK1

時間生物学 Vol. 24, No. 2 (2018) 1 1

P060 Characteri ation of ew Periodic Physiological Response Conferring Photosynthetic Advantage

P061 ead one formation by saturated reactions in circadian clocks

P062 Characteri ation of circadian rhythms of cells isolated from leaves and roots in Arabidopsis

P06 Exhaustive screening for AL lines expressing in subsets of circadian clock neurons in Drosophila melanogaster

AL

P06 Cyanobacterial circadian clock based on two A Pase activities of KaiC KaiC A Pase

P06 Analysis of primitive sleep-wake cycle in hydra

P066 Modeling of entrainment manners of the circadian rhythm to light-dark cycles

時間生物学 Vol. 24, No. 2 (2018)

P067 A mathematical model for transient dissociation of Per1 and Bmal1 rhythms in the suprachiasmatic nuclues

P068 heoretical study on the evolution of self-sustainability of circadian clocks

P069 he novel circadian neurotransmitter CC amide1 modulates outputs from s-L v clock neurons in Drosophila melanogaster

CC amide1 s-L v

P070 he circadian clock controls cell-fate determination through cell cycle

P071 Prediction of the regulation of circadian clocks by R A methylation and a theoretical study on circadian period

R A

P072 Effect of clock gene mutations on entrainment properties in the plant circadian clock

P07 earch for proteins involved in the degradation of KaiC and the effect on rhythm by KaiC turnover

KaiC KaiC

時間生物学 Vol. 24, No. 2 (2018) 1

P07 Analysis of phase differences of circadian rhythms between plant bodies during clonal proliferation of duckweed

P07 Evaluation of effects of clock-gene deficiency on circadian properties of individual cells in Arabidopsis leaves

P076 easonal changes of the daily expression pattern of the clock-related genes in Arabidopsis halleri

P077 Resonance of low-temperature-induced damped circadian socialation in cyanobacteria

P078 Regulation of flowering by light and temperature

P079 Circatidal rhythm in the soldier crab Mictyris guinotae

P080 Relationship of the timing of eclosion of the onion fly Delia antiqua to the amplitude of s uare-wave and pseudo-sinusoidal temperature cycles

時間生物学 Vol. 24, No. 2 (2018)

P081 Entrainment of the circadian clock in duckweed plants to periodic changes of sucrose concentration in the culture medium

P082 Real-time monitoring of key gene products involved in photoperiodic flowering in rice using gene-targeted L C reporter

P08 Entrainment of ultradian rhythms of chromate in Uroteuthis edulis

P08 A small molecule changing circadian period to 8 h

P08 isappearance of circadian rhythm of rapidly dividing cyanobacteria

P086 Drosophila insulin-like peptide (Dilp) 3 regulates circadian rhythm in Drosophila melanogaster Drosophila insulin-like peptide (Dilp) 3

P087 Comparative characteri ation of circadian behaviors between species in the Lemna genus and Wolffiella genus

Lemna Wolffiella

時間生物学 Vol. 24, No. 2 (2018) 1

P088 Resonance of circadian rhythms of Arabidopsis under low temperature

P089 ptimum analysis of low density time course data in identification of crop circadian rhythm

P090 Effects of environmental factors on circadian rhythms of ebrafish BRF 1 cells BRF 1

P091 he mechanism to share time-information between tissues in Arabidopsis thaliana

P092 Cell-type specific clock system regulates plant cell fate

P09 Effects of a uaporin on the rhythm of Marsilea leaf opening

P09 Lunar and daily transcription of Cryptochrome2 in the brain of a tropical grouper Cryptochrome2

P09 leep-regulating neuronal circuit in the central complex in Drosophila

-時間生物学 Vol. 24, No. 2 (2018)

P096

P097 Rhythmicity in poly(A) tail length is regulated primarily by deadenylation

P098 Elucidation of the mammalian circadian clock mechanism by chemical biology approaches

P099 Roles of FBXL21 on CRY protein function

CRY FBXL21

P100 Cyanobacterial circadian rhythm of non-photoactive intracellular redox and the antioxidant function

P101 Analysis on rhythmic gene expression without KaiC phosphorylation cycle in the kaiCEE_{mutant cells}

KaiC kaiCEE

P102 BMAL1-dependent activation of stress responsive transcription factors regulate protective response to ultra-violet irradiation

時間生物学 Vol. 24, No. 2 (2018) 1

P10 A R -type E ubi uitin ligase regulates BP protein degradation

BP R E

P10 Circadian period extension due to impairment of A PARP1 A PARP1

P10 Changes in Circadian Clock Properties of Replicative enescent - cells

P106 Effect of redox perturbation via redox-active polymer on mammalian circadian clock

時間生物学 Vol. 24, No. 2 (2018)

時間生物学 Vol. 24, No. 2 (2018)

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8 7-8 -1 EL09 6-2 -2112 8 2-8107 12-19 EL09 -8 - 171

実験用特注冶具等の製作します。

E-mail: [email protected]

HP: http://www.jp-factory.co.jp

株式会社 J・P・F

特注例：生物発光測定用PMT保持冶具

血管機能検査の新時代

CAVI/ABI TBI 負荷後ABI 大動脈PWV 分節脈波 リズム計測_検査 標準12誘導_{心電図検査}マスターテスト_検査 ファイル通信 日報 オーダリング 検査登録

VS-3000TE ● ● ● ● ■ ● ● ● ● ● ● ● VS-3000TN ● ● ● ● ■ ● ■ ■ ● ● ● ● VS-3000E ● - ● ● - ● ● ● ● ● ● ● VS-3000N ● - ● ● - ● ■ ■ ● ● ● ● ■ VS-3000TN、VS-3000Nは、心電ソフトパッケージVSC-300E（オプション） と、心電アンプモジュールEE-40（オプション）を追加することで使用できるようになります。 ■VS-3000TN、VS-3000TEは、分節脈波ユニットSPU-30（オプション）を追加することで使用できるようになります。 VS -300 0シリーズ CAVI ABI PVR ECG 医療機器認証番号：224ADBZX00086000 ● 末梢動脈疾患（PAD）の鑑別診断・重症度判定 ABIは、下肢動脈の狭窄・閉塞を評価する指標です。PAD は、心血管疾患、脳血管疾患など、他臓器障害との合併 が多く見られることから、早期発見が重要とされています。

ABI

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