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Acta Medica Kindai University

Volume 45, No.2       December 2020 CONTENTS

Originals

Folic acid intake of female nursing course students according to a dietary habits survey

Takuya Matsuo ���������������������������������������������������������������������������������������������������������������������� 21

NF1 and KRAS mutations in pancreatic cancer secondary to alcoholic chronic pancreatitis Takaaki Murase, Kazuko Sakai, Takao Satou, Kazuto Nishio,

Yoshifumi Takeyama ������������������������������������������������������������������������������������������������������������� 31 Left and right cardiac performance in children with small heart syndrome

– Analysis with cardiac MRI –

Kosuke Nishi, Satoshi Marutani, Nori Takada, Kazushi Ueshima,

Keisuke Sugimoto, Noboru Inamura ��������������������������������������������������������������������������������������� 39

Case Reports

HELLP syndrome at 22 weeks of gestation with resulting stillbirth and a favorable outcome in a subsequentpregnancy: A case report

Akiko Kanto, Kosuke Murakami, Yoshie Yo, Masao Shimaoka,

Reona Shiro, Noriomi Matsumura ������������������������������������������������������������������������������������������ 47

Recurrent atypical cutaneous lesions of IgA vasculitis successfully treated with colchicine: a case report

Koji Yamasaki, Satoshi Marutani, Shunsuke Minakata, Keisuke Sugimoto ������������������������������ 53

Index(Vol�45,No1,No2) ����������������������������������������������������������������������������������������������������������������� 59

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Author Index (Vol.45, No.1, No.2)

F Fujii K ...13 Fujinami N ... 1 Fujishima R ... 1 H Hamada R ...13 I Imura M ...13 Inamura N ...39 K KanedaT ...13 Kanto A ...47 M Marutani S ... 39,53 Matsumura N ... 1,47 Matsuo T ...21 Minakata S ...53 Miyashita N ...13 Murakami K ...47 Murase T ...31 N Nishi K ...39 Nishino T ...13 Nishio K ...31 S Sakaguchi G ...13 Sakai K ...31 Satou T ...31 Shimaoka M ...47 Shiro R ...47 Sugimoto K ... 39,53 T Takada N ...39 Takeyama Y ...31 Tsuji I ... 1 U UeshimaK ...39 Y Yamasaki K ...53 Yo Y ...47 Yukami S ...13

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Author Index (Vol.45, No.1, No.2)

F Fujii K ...13 Fujinami N ... 1 Fujishima R ... 1 H Hamada R ...13 I Imura M ...13 Inamura N ...39 K KanedaT ...13 Kanto A ...47 M Marutani S ... 39,53 Matsumura N ... 1,47 Matsuo T ...21 Minakata S ...53 Miyashita N ...13 Murakami K ...47 Murase T ...31 N Nishi K ...39 Nishino T ...13 Nishio K ...31 S Sakaguchi G ...13 Sakai K ...31 Satou T ...31 Shimaoka M ...47 Shiro R ...47 Sugimoto K ... 39,53 T Takada N ...39 Takeyama Y ...31 Tsuji I ... 1 U UeshimaK ...39 Y Yamasaki K ...53 Yo Y ...47 Yukami S ...13

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Subject Index (Vol.45, No.1, No.2)

A

Atypical cutaneous lesions ...53

ART ... 1

B babies and infants ...13

C Cardiac performance ...39 Children ...39 Chronic pancreatitis ...31 Colchicine ...53 D dietary habit ...21 E endometrioma ... 1 F folic acid ...21

food frequency questionnaire ...21

G Gene mutation ...31

H HELLP syndrome ...47

hypertensive disorder of pregnancy ...47

I Immunoglobulin A vasculitis ...53 infertility ... 1 K KRAS ...31 L left side atrioventricular valve ...13

long term results ...13

M MRI ...39

N Next-generation sequencing ...31

neural tube defects ...21

NF1 ...31 O omit meals ...21 Orthostatic dysregulation ...39 ovarian reserve ... 1 P Pancreatic cancer ...31 preeclampsia ...47 R Relapse ...53 re-operation ...13 S second trimester ...47

Small heart syndrome...39

stillbirth ...47

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i

INFORMATION FOR AUTHORS

Manuscripts

Manuscripts containing original materials are accepted for consideration on the understanding that neither the article nor any part of its essen-tial substance, tables, or figures has been or will be published or submitted for publication else-where before appearing in the Journal. This striction does not apply to abstracts or press re-ports published in connection with scientific meetings. Copies of any closely related manu-scripts should be submitted to the Editor to-gether with the manuscript that is to be consid-ered by the Journal. The submission of more than one article dealing with related aspects of the same study is discouraged.

The original manuscript with one set of orig-inal figures and four copies of the complete manuscript should be submitted. Only one copy will be returned to authors. Manuscripts must be no longer than 3000 words.

Please supply an approximate word count (ex-cluding abstract and references). Use stand-ard-sized paper, and triple-spacing throughout. All submissions should be addressed to :

the Editor-in-chief, Editorial Office of Kindai University Medical Association, Kindai Univer-sity School of Medicine,

377-2 Ohnohigashi, Osakasayama 589-8511, Japan

Tel. : 0723-66-0221, ext, 3218, Fax. : 0723-66-8810

E-Mail : henshu @ med.kindai.ac.jp

by the author personally and should be sent by registered mail.

A covering letter signed by all authors should identify the person (with address and telephone number) responsible for any questions or nego-tiations regarding the manuscript ; this letter should make it clear that the finally submitted manuscript has been seen and proved by all au-thors, and that they have taken due care to en-sure the integrity of their work. At least one person’s name must accompany any group names (e.g., “Thelma J.Smith, for the Kawachi Porphyria Group”).

Acknowledgments will be limited to a column of Journal space, and those acknowledged will

be listed only once. Letters to the Editor

Letters to the Editor should offer short, deci-sive observations of interest based on published data. They should not be preliminary observa-tions that may need a later paper for validation. Conflicts of Interest

Authors of research articles should disclose at the time of submission any financial arrange-ments they may have with any company whose product figures prominently in the submitted manuscript or with any company making a com-peting product. Such information will be held in confidence while the paper is under review and will not influence the editorial decision. However, if the article is subsequently accepted for publication, the editors will usually discuss with the authors the manner in which such infor-mation is to be communicated to the reader.

Since the essence of reviews and editorials is informed selection and interpretation of the lit-erature, the Journal expects that authors of such articles will not have any financial interest in any company (or any of its competitors), making a product discussed in the article.

Announcements

Announcements of scientific meetings, con-ferences and other events that are of interest to the readership of Acta Medica Kindai University (Acta Med Kindai Univ) should be sent to the Editor at least 4 months prior to the intended data of publication.

Review Articles

Review atticles on topics of broad interest are strongly desired and may be solicited by the Ed-itor-in-Chief. Individuals who wish to prepare review articles should correspond directly with the Editor-in-Chief regarding the appropriate-ness of the proposed topic. Such articles are expected to be thorough, detailed, and should

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in-INFORMATION FOR AUTHORS clude appropriate references to the literature.

The addition of tables and figures to summarize critical points is encouraged. These articles are themselves reviewed by the Editors and other expert reviewers before a final decision on publication is made, and revisions may be re-quired.

Titles and Authors’ Names

With each manuscript, provide a title page giving the following : the title of the paper (titles should be concise and descriptive, not declara-tive); a running head of fewer than 40 letter spaces ; the name(s) of the author(s), including first name(s) in full ; the name of the department and/or institution in which the work was done ; the institutional affiliation of each author ; and the name and address of the author to whom re-print requests should be addressed.

Abstracts

Provide on a separate page an abstract of not more than 250 words. This abstract should consist of four paragraphs, entitled Background, Methods, Results, and Conclusions. The text should thus briefly describe, respectively, the problem being addressed in the study, how the study was performed, the salient results, and what the authors conclude from the results. Key Words

Three to 10 key words or short phrases should be added to the bottom of the abstract page. Employ terms from the Medical Subject Head-ings of Index Medicus.

References

List double-spaced references in numerical order at the end of the article according to their order of citation in the text. Include all authors’ names, full article titles, and full publication de-tails, or the most complete information available for articles “in press”. If more than five au-thors, include the first author followed by et al. Abbreviate the names of journals according to the scheme used in the latest edition of Index Medicus (Superintendent of Documents, US Government Printing Office, Washington, DC 20402 U.S.A.). References to abstracts and

letters must be appropriately identified Personal communications, unpublished observations, and manuscripts submitted and “in preparation” must appear parenthetically in the text. Writ-ten permission must be submitted when citing any personal communications.

Examples of Reference Style

Journal articles, one or more authors :

1. Ashida T, et al. (1993) Change of serum erythropoietin levels after allogeneic bone marrow transplantation. Acta Med Kindai Univ 18: 13-19

Journal article, in press :

2. Foroni L, et al. Rearrangement of the T-cell receptor delta genes in human T cell leuke-mias. Blood (in press)

Complete book :

3. Adams DO, Edelson PJ, Koren HS (1981) M ethods for Studying M ononuclear Phagocytes. San Diego, CA, Academic Press, pp 1-293 Chapter of book :

4. Sallan SE, Weinstein HJ (1987) Childhood acute leukemia, In : Nathan DG, Oski FA (eds): Hematology of Infancy and Childhood, Vol 2. Philadelphia, PA, Saunders, pp 1028-1031

Chapter of book that is part of a published meet-ing :

5. Baron MH, Maniatis T (1987) Stage-specific reprogramming of globin gene expression, In : Stamatoyannopoulos G, Nienhuis AW (eds): Developmental Control of Globin Gene Ex-pression, Proceedings of the Fifth Conference on Hemoglobin Switching. New York, NY, Liss, pp 143-168

Chapter of book that is part of an unpublished meeting :

6. Freireich EJ (1988) Methotrexate to molec-ular genetics : Forty years of leukemia treat-ment. XXII Congress of the International So-ciety of Hematology. Milan, Italy, p 27 Abstract :

7. Clift RA, Martin P, Fisher L, Buckner CD, Thomas ED (1987) Allogenic marrow trans-plantation for CML in accelerated phase-risk factors for survival and relapse. Blood 70 : 291a (abstr)

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INFORMATION FOR AUTHORS

ii

clude appropriate references to the literature. The addition of tables and figures to summarize critical points is encouraged. These articles are themselves reviewed by the Editors and other expert reviewers before a final decision on publication is made, and revisions may be re-quired.

Titles and Authors’ Names

With each manuscript, provide a title page giving the following : the title of the paper (titles should be concise and descriptive, not declara-tive); a running head of fewer than 40 letter spaces ; the name(s) of the author(s), including first name(s) in full ; the name of the department and/or institution in which the work was done ; the institutional affiliation of each author ; and the name and address of the author to whom re-print requests should be addressed.

Abstracts

Provide on a separate page an abstract of not more than 250 words. This abstract should consist of four paragraphs, entitled Background, Methods, Results, and Conclusions. The text should thus briefly describe, respectively, the problem being addressed in the study, how the study was performed, the salient results, and what the authors conclude from the results. Key Words

Three to 10 key words or short phrases should be added to the bottom of the abstract page. Employ terms from the Medical Subject Head-ings of Index Medicus.

References

List double-spaced references in numerical order at the end of the article according to their order of citation in the text. Include all authors’ names, full article titles, and full publication de-tails, or the most complete information available for articles “in press”. If more than five au-thors, include the first author followed by et al. Abbreviate the names of journals according to the scheme used in the latest edition of Index Medicus (Superintendent of Documents, US Government Printing Office, Washington, DC 20402 U.S.A.). References to abstracts and

letters must be appropriately identified Personal communications, unpublished observations, and manuscripts submitted and “in preparation” must appear parenthetically in the text. Writ-ten permission must be submitted when citing any personal communications.

Examples of Reference Style

Journal articles, one or more authors :

1. Ashida T, et al. (1993) Change of serum erythropoietin levels after allogeneic bone marrow transplantation. Acta Med Kindai Univ 18: 13-19

Journal article, in press :

2. Foroni L, et al. Rearrangement of the T-cell receptor delta genes in human T cell leuke-mias. Blood (in press)

Complete book :

3. Adams DO, Edelson PJ, Koren HS (1981) M ethods for Studying M ononuclear Phagocytes. San Diego, CA, Academic Press, pp 1-293 Chapter of book :

4. Sallan SE, Weinstein HJ (1987) Childhood acute leukemia, In : Nathan DG, Oski FA (eds): Hematology of Infancy and Childhood, Vol 2. Philadelphia, PA, Saunders, pp 1028-1031

Chapter of book that is part of a published meet-ing :

5. Baron MH, Maniatis T (1987) Stage-specific reprogramming of globin gene expression, In : Stamatoyannopoulos G, Nienhuis AW (eds): Developmental Control of Globin Gene Ex-pression, Proceedings of the Fifth Conference on Hemoglobin Switching. New York, NY, Liss, pp 143-168

Chapter of book that is part of an unpublished meeting :

6. Freireich EJ (1988) Methotrexate to molec-ular genetics : Forty years of leukemia treat-ment. XXII Congress of the International So-ciety of Hematology. Milan, Italy, p 27 Abstract :

7. Clift RA, Martin P, Fisher L, Buckner CD, Thomas ED (1987) Allogenic marrow trans-plantation for CML in accelerated phase-risk factors for survival and relapse. Blood 70 : 291a (abstr)

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INFORMATION FOR AUTHORS Footnotes and Abbreviations

Footnotes should appear at the bottom of their respective pages. Abbreviations should be de-fined at their first use and applied consistently throughout the article. Do not employ non-standard abbreviations or abbreviate term ap-pearing fewer than three times. Give the chem-ical name of a compound after the first use of the trivial name; the trivial name may then fol-low throughout the article. Abbreviate units of measure only when used with numbers.

Tables

Each table should be printed or typed on a separate page. Tables should be appropriately numbered, using Arabic numerals and cited in numerical order in the text. Legends providing sufficient explanation to make the date intelligi-ble without reference to the text must be typed on the same page.

Figures and Figure Legends

Figures must be cited in the text in numerical order using Arabic numerals. For photographs, submit three complete sets of clear, glossy, blackand-white prints. For line drawings, ei-ther a single set of photographs with three sets of copies, or three sets of high-quality laser fig-ures are acceptable. Do not write on either the front or back of any photographs. Do not mount the figures, fasten them with paper-clips, or store them in clasp envelopes where the clasp can cause damage in transit The name of the first author, the figure number, and designated top of the figure should be typed on a label affixed to the back of each figure. Figure legends should be typed double-spaced on a separate sheet, and should include a brief title and concise explana-tion for each figure, as appropriate. The cost of publising color photographs will be borne by the authors.

Submission on Computer Disk

Authors of accepted and revised manuscripts are required to submit the final version of their paper on disk for typesetting. Please do not forget to sign and indicate the following on the form : the file name, operating system, and word processing software with version. Two

hard-copy versions of the manuscript that match the disk exactly are always required.

Proofreading

Authors of accepted manuscripts will receive galley proofs directly from the publisher. Reprints

Reprints must be ordered in advance. An or-der form indicating the cost of reprints will be sent directly from the publisher with the galleys proofs. Reprints orders, payments, and enquir-ies should be directed to the Editorial Office. Ethical Approval

Human experiments : Intended studies on hu-man subjects can proceed only after the investi-gations have obtained the voluntary consent of the subjects. A full explanation of the experi-ments must be made to the subjects before their consent is requested. Authors should draw at-tention to the Code of Ethics of the World Med-ical Association (Declaration of Helsinki, 1964, and Declaration of Tokyo, 1975). Approval in writing is also required for the performance of such experiments from the Chairman or the Eth-ics Committee of the relevant University, Re-search Institute or Hospital.

Animal experiments : Animal experiments must be performed so as to cause the least pos-sible pain or discomfort to the animals. Ac-cordingly, any anesthetic procedures employed must be described in detail including measures taken to maintain a satisfactory level of pain avoidance both during and after the experi-mental procedures. Muscle relaxants and par-alytic agents are not of themselves anesthetics, and they should always be used in combination with drugs that are known to produce adequate analgesia.

Experimental animals must be maintained ac-cording to recognized standards designed to safeguard their welfare. This includes proper housing and food, as well as appropriate sanitary conditions. In this connection, investigators must be aware of the legal requirements for ani-mal husbandry. They are also obliged to fol-low the Guiding Principles for the Care and Use of Animals.

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INFORMATION FOR AUTHORS

iv

provide satisfactory evidence of having fol-lowed the above requirements will be rejected after consideration by the Editorial Board of the Journal.

Copyright

The copyright to the article is transferred to Kindai University effective if and when the

ar-ticle is accepted for publication by Acta Medica Kindai University. The copyright covers the exclusive right to reproduce and distribute the article, including reprints, translations, photo-graphic reproductions, electronic form or any other reproductions of similar nature. The sub-mitting/corresponding author declares that all co-authors of this article have been informed of the submission.

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THE KINDAI UNIVERSITY MEDICAL ASSOCIATION

President : ITARU MATSUMURA Vice-President : YUJI TOHDA

Adviser : MASAYUKI IKI

The Association publishes two official journals, one in English and the other in Japanese. The Acta Medica Kindai University is published in English for original work in all branches of medical sciences. Papers from other institutions, inland or abroad, are also accepted.

The Medical Journal of Kindai University is published in Japanese for original work in medical sciences and related fields. Papers from other institution are also accepted.

Submission of manuscripts, correspondence concerning exchange of publications,subscriptions and other matters should be addressed to :

The Editorial Board

Kindai University Medical Association, Kindai University Faculty of Medicine, Osakasayama, Osaka 589-8511

Japan

ACTA MEDICA KINDAI UNIVERSITY

MEDICAL JOURNAL OF KINDAI UNIVERSITY

Editor-in-Chief Editorial Board M.INASE H . IKEGAMI I . MATSUMURA K . NAKAGAWA A . ITO S . NAKAO T . KAMISAKO M . MIYAZAWA K . NISHIO Y . TAKEYAMA M . OKADA S . TATSUMI

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