◊✲༠ຊ⪅ ᕝ⏿ᣅஓ ᆅ᪉⊂❧⾜ᨻἲே ኱㜰೺ᗣᏳ඲ᇶ┙◊✲ᡤ

(1)

ཌ⏕ປാ⛉Ꮫ◊✲㈝⿵ຓ㔠 ࢚࠙࢖ࢬᑐ⟇ᨻ⟇◊✲஦ᴗࠚ HIV᳨ᰝཷ᳨່ዡ࡟㛵ࡍࡿ◊✲

(⥲ྜ)◊✲ሗ࿌᭩

࢚ࣅࢹࣥࢫ࡟ࡶ࡜࡙࠸ࡓࠊ

HIV ᳨ᰝ࡟㛵ࡍࡿ Q&A 㞟㸦ᑓ㛛⫋ྥࡅ㸧ࡢసᡂ

◊✲ศᢸ⪅ ຍ⸨┿࿃ ៞᠕⩏ሿ኱Ꮫ་Ꮫ㒊 ᚤ⏕≀Ꮫ࣭ච␿Ꮫᩍᐊ

◊✲༠ຊ⪅ ᕝ⏿ᣅஓ ᆅ᪉⊂❧⾜ᨻἲே ኱㜰೺ᗣᏳ඲ᇶ┙◊✲ᡤ

஭ᡞ⏣୍ᮁ ࡋࡽ࠿ࡤデ⒪ᡤ

ᑠᓥὒᏊ ᆅ᪉⊂❧⾜ᨻἲே ኱㜰೺ᗣᏳ඲ᇶ┙◊✲ᡤ

㏆⸨┿つᏊ ⚄ዉᕝ┴⾨⏕◊✲ᡤ

㈆༖೺ྖ ᮾி㒔೺ᗣᏳ඲◊✲ࢭࣥࢱ࣮

బ㔝㈗Ꮚ ⚄ዉᕝ┴⾨⏕◊✲ᡤ

㡲⸨ᘯ஧ ៞᠕⩏ሿ኱Ꮫ་Ꮫ㒊 ᚤ⏕≀Ꮫ࣭ච␿Ꮫᩍᐊ 㧗⏣ ᪼ ୰ᅜ㟁ຊᰴᘧ఍♫୰㟁⑓㝔

㛗ᓥ┿⨾ ᮾி㒔೺ᗣᏳ඲◊✲ࢭࣥࢱ࣮

᳃ ἞௦ ᆅ᪉⊂❧⾜ᨻἲே ኱㜰೺ᗣᏳ඲ᇶ┙◊✲ᡤ

A.◊✲┠ⓗ

⮬἞యࡀಖ೺ᡤࡸ≉タ᳨ᰝሙ࡛ᐇ᪋ࡍࡿ↓ᩱ

༏ྡHIV᳨ᰝࡸࠊ་⒪ᶵ㛵࡟࠾ࡅࡿHIV᳨ᰝ࡞

࡝ࠊᵝࠎ࡞HIV᳨ᰝࡢ⌧ሙ࡛ά⏝࡛ࡁࡿࠕ᳨ᰝ

࡟≉໬ࡋࡓࠖ㈨ᩱ㞟ࡣࡇࢀࡲ࡛ぢᙜࡓࡽ࡞࠿ࡗࡓࠋ ࡑࡇ࡛ࠊ᭱᪂ࡢ࢚ࣅࢹࣥࢫ࡟ᇶ࡙࠸ࡓHIV᳨ᰝ

࡟㛵ࡍࡿ㈨ᩱ㞟ࢆసᡂࡍࡿࡇ࡜࡜ࡋࡓࠋ

B.◊✲᪉ἲ

஦๓࡟኱㜰ᗓಖ೺ᡤࡢ᳨ᰝᐊᢸᙜ⫋ဨ࡟࢔ࣥ

ࢣ࣮ࢺㄪᰝࢆ⾜࠸ࠊ᳨ᰝᢸᙜ⪅࡟࠾ࡅࡿࢽ࣮ࢬࡢ ᢕᥱࢆᐇ᪋ࡋࡓࠋࡑࡢ⤖ᯝ࠿ࡽࠊ㉁ၥࡀከ࠿ࡗࡓ

Ⅼࢆ୰ᚰ࡟ࠊ㈨ᩱ࡟┒ࡾ㎸ࡳゎㄝࡍࡿ㡯┠ࢆỴᐃ ࡋࡓࠋࡲࡓࠊ㈨ᩱࡣᡭ࡟ྲྀࡗࡓ⪅ࡀ࡞ࡌࡳࡸࡍ࠸

ᵝࠊQ&A㞟ࡢయ⿢ࢆ࡜ࡿࡇ࡜࡜ࡋࡓࠋࡑࡢᚋࠊ

⦅㞟ጤဨ࡛ゎㄝ㡯┠㸦㉁ၥ㸧ࢆศᢸࡋࠊྛ㉁ၥ࡟

ᑐࡍࡿᅇ⟅ࢆࠊᩥ⊩ࢆᘬ⏝ࡋ࡞ࡀࡽసᡂࡋࡓࠋࡉ

ࡽ࡟๓㏙ࡢᮏᩥ㡯┠࡟ຍ࠼ࠊᮏᩥ୰࡟㢖ฟࡋࡓㄒ

ྃ࡟ࡘ࠸࡚ࠊࠕ␎ㄒゎㄝࠖ࡜ࡋ࡚ྛㄒྃࡢゎㄝࢆ

ᮏᩥࡢ๓࡟௜グࡋࡓࠋ (೔⌮㠃࡬ࡢ㓄៖)

Q&A㞟ࡢసᡂ࡟ࡣࠊHIV㝧ᛶ⪅➼ᙜ஦⪅ࡢேᶒ

࡟༑ศ㓄៖ࡋࡓࠋ

C.◊✲⤖ᯝ

Q&A࡜ࡋ࡚᥇⏝ࡋࡓ㉁ၥ஦㡯ࡣሙ㠃ࡈ࡜࡟୕

❶࡟ศࡅࡓࠋ

➨୍❶ࡢࠕHIV᳨ᰝࡢᇶ♏▱㆑ࠖ࡜ࡋ࡚ࡣࠊ

࣭HIV᳨ᰝࡢᡭ㡰ࡣ㸽

࣭ࠕ࢘࢖ࣥࢻ࢘ᮇࠖ࡜ࡣ࡞ࢇ࡛ࡍ࠿㸽

◊✲せ᪨

HIV᳨ᰝ࡟ᦠࢃࡿ་ᖌࡸ⑓㝔┳ㆤᖌࠊ᳨ᰝᢏᖌࡸࠊ⮬἞యࡢಖ೺ᖌࡸ⾜ᨻࡢᢸᙜ⪅ࠊNPO/CBOࡢ 㛵ಀ⪅ࡀ᪥ࠎ┤㠃ࡍࡿ HIV ᳨ᰝ࡟ᑐࡍࡿ㉁ၥࡸ␲ၥࢆゎᾘࡍࡿࡓࡵࠊ᭱᪂ࡢ࢚ࣅࢹࣥࢫ࡟ᇶ࡙࠸ࡓ ࠕHIV᳨ᰝ࡟㛵ࡍࡿQ&Aࠖ㞟ࡢసᡂ࡟ྲྀࡾ⤌ࢇࡔࠋ

ෆᐜࡣᡭ࡟ྲྀࡾࡸࡍ࠸ࡼ࠺Q&A㞟ࡢయ⿢࡜ࡋࠊࡲࡓᕳ㢌࡟ࡣ␎ㄒゎㄝࢆຍ࠼ࡓࠋ

(2)

࣭ࢫࢡ࣮ࣜࢽࣥࢢ᳨ᰝࡢࠕ㝧ᛶࠖࠕഇ㝧ᛶࠖ࡟ࡘ

࠸࡚ᩍ࠼࡚ୗࡉ࠸ࠋ

࣭☜ㄆ᳨ᰝ࡟ࡣ࡝ࡢࡼ࠺࡞᪉ἲࡀ࠶ࡾࡲࡍ࠿㸽

࣭HIV᳨ᰝ࡛㝧ᛶ࡟࡞ࡗࡓሙྜࠊ࡝࠺ࡍࢀࡤⰋ

࠸࡛ࡍ࠿㸽 ࡢ5㡯┠ࢆ᥇⏝ࡋࡓࠋ

➨஧❶ࡢࠕ་⒪ᶵ㛵࡟࠾ࡅࡿHIV᳨ᰝࠖ࡟࠾࠸

࡚ࡣࠊ

࣭HIV᳨ᰝࡢಖ㝤㐺ᛂ࡟ࡘ࠸࡚ᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

࣭HIV᳨ᰝ⤖ᯝ࡟㛵ࡍࡿ᝟ሗࡣࠊ≉ู࡞ᢅ࠸ࡀ ᚲせ࡛ࡍ࠿㸽

࣭HIV᳨ᰝࡢྠពྲྀᚓࡣ࡝࠺ࡍࢀࡤࡼ࠸࡛ࡍ

࠿㸽

࣭㔪่ࡋ➼HIVᭀ㟢஦ᨾⓎ⏕㸟 HIV᳨ᰝࡣ࡝

࠺ࡍࢀࡤ㸽

࣭HIV☜ㄆ᳨ᰝࡢᡤせ᫬㛫ࡣ▷ࡃฟ᮶࡞࠸ࡢ࡛

ࡋࡻ࠺࠿㸽

࣭㒑㏦᳨ᰝ㸦HIV᳨ᰝ࢟ࢵࢺ㸧࡜ࡣఱ࡛ࡍ࠿㸽 ࡢ6㡯┠ࢆ᥇⏝ࡋࡓࠋ

➨୕❶ࡢࠕHIV᳨ᰝᢸᙜ⪅ྥࡅࠖ࡟ࡣࠊ

࣭ࢫࢡ࣮ࣜࢽࣥࢢ᳨ᰝࡢഇ㝧ᛶ⋡࡟ࡘ࠸࡚ࠊᩍ

࠼࡚ࡃࡔࡉ࠸ࠋ

࣭HIV㎿㏿᳨ᰝヨ⸆ࡢ≉ᚩ࡟ࡘ࠸࡚ࠊᩍ࠼࡚ࡃ ࡔࡉ࠸ࠋ

࣭HIV༶᪥᳨ᰝᐇ᪋ࡢὀពⅬ࡟ࡘ࠸࡚ࠊᩍ࠼࡚

ࡃࡔࡉ࠸ࠋ

࣭☜ㄆ᳨ᰝࡢ᪉ἲ࡟ࡘ࠸࡚ࠊᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

࣭WBἲࡢ⤖ᯝࡢゎ㔘࡟ࡘ࠸࡚ࠊᩍ࠼࡚ࡃࡔࡉ

࠸ࠋ

᳨࣭ᰝᑐ㇟㞟ᅋࡈ࡜ࡢ㝧ᛶ⋡࡜㝧ᛶⓗ୰⋡࡟ࡘ

࠸࡚ᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

࣭HIVᛴᛶឤᰁ࡟ࡘ࠸࡚ࠊᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

࣭HIVᢠཎ㝧ᛶ᫬ࡢ☜ㄆ᳨ᰝࡢ㐍ࡵ᪉࡟ࡘ࠸࡚ࠊ ᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

࣭NAT᳨ᰝ࡟ࡘ࠸࡚ࠊᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

࣭KK-TaqManἲ࡟ࡘ࠸࡚ࠊᩍ࠼࡚ࡃࡔࡉ࠸ࠋ

ࡢ10㡯┠ࢆ᥇⏝ࡋࡓࠋ

ࡉࡽ࡟ࠊୖグࡢᮏᩥ㡯┠࡟ຍ࠼ࠊࠕ␎ㄒゎㄝࠖ

ࢆຍ࠼ࡓࠋ᥇⏝ࡋࡓ␎ㄒࡣࠊᮏᩥ୰࡟㢖ฟࡋࡓ௨

ୗࡢ25ࡢㄒྃ࡜ࡋࡓࠋ

㹁㹂㹁 ࠊ 㹁㹊㹇㸿 ἲ ࠊ 㹁㹐㹄 ࠊ 㹂㹎㹁 ࠊ 㹃㹇㸿 ἲ ࠊ 㹃㹊㹇㹑㸿 ἲ ࠊ 㹃㹌㹔㸦env㸧ࠊ 㹅㸿㹅㸦g a g㸧ࠊ 㹅㹎 ࠊ 㹆㹀㹱 ᢠ ཎ ࠊ 㹆㹁㹔 ᢠ య ࠊ 㹆㹇㹔 ࠊ 㹇㹁 ἲ ࠊ 㹧㹬㹦㹭㹳㹱㹣ࠊ㹊㹒㹐ࠊ㹋㹑㹋ࠊ㹌㸿㹒ࠊ 㹎㸿 ἲ ࠊ 㹎㹍㹊㸦p o l㸧ࠊ 㹐㹌㸿 ࠊ 㹐㹒 ࠊ 㹐㹒−㹎㹁㹐ࠊ㹓㹌㸿㹇㹂㹑ࠊ㹕㹀ࠊ㹕㹆㹍ࠋ

D.⪃ᐹ

ࡇࢀࡲ࡛HIV☜ㄆ᳨ᰝ࡟฼⏝ࡉࢀ࡚ࡁࡓ࠸ࡃ ࡘ࠿ࡢ᳨ᰝヨ⸆ࡀ㈍኎୰Ṇ࡟࡞ࡾࠊࡲࡓ୍᪉࡛ࠊ WBἲ࡟௦ࢃࡿ᪂ࡋ࠸᳨ᰝヨ⸆ࡀయእデ᩿⸆࡜ࡋ

࡚᪂ࡓ࡟ᢎㄆࡉࢀࡿ࡞࡝ࠊ⌧ᅾࠊHIV᳨ᰝࡣ㐣Ώ ᮇ࡟࠶ࡿ࡜⪃࠼ࡽࢀࡿࠋᮏQ&A㞟ࡢసᡂ࡟࠶ࡓ ࡗ࡚ࡣࠊHIV᳨ᰝࡢ⌧≧࡟༶ࡋࡓෆᐜ࡟ຍ࠼ࠊྍ

⬟࡞㝈ࡾHIV᳨ᰝࡢ᪂ࡋ࠸ኚ໬࡟༶ࡋࡓෆᐜ࡜

࡞ࡿࡼ࠺᳨ウࡋࡓ࠸࡜⪃࠼࡚࠸ࡿࠋ

᏶ᡂᚋࡣ඲ᅜࡢಖ೺ᡤࡸ≉タ᳨ᰝሙ࡟㓄௜ࡋ ࡓࡾweb࡟PDF∧ࢆweb࡟ᥖ㍕ࡋࡓࡾࡋ࡚ᐇ㝿

࡟౑⏝ࡋ࡚ࡶࡽ࠸ࠊࡑࡢᚋࠊ࢔ࣥࢣ࣮ࢺㄪᰝࢆ⾜

࠺ࡇ࡜࡛ࠊ౑⏝ឤࡸពぢࡢࣇ࢕࣮ࢻࣂࢵࢡࢆᚓࡓ

࠸ࠋ

E.⤖ㄽ

⮬἞యࡀಖ೺ᡤࡸ≉タ᳨ᰝሙ࡛ᐇ᪋ࡍࡿ↓ᩱ

༏ྡHIV᳨ᰝࡸࠊ་⒪ᶵ㛵࡟࠾ࡅࡿHIV᳨ᰝ࡞

࡝ࠊᵝࠎ࡞⌧ሙ࡛ά⏝࡛ࡁࡿࠕ᳨ᰝ࡟≉໬ࡋࡓࠖ

㈨ᩱ㞟ࡣࡇࢀࡲ࡛ぢᙜࡓࡽ࡞࠿ࡗࡓࠋࡑࡇ࡛ࠊ HIV᳨ᰝ࡟ᦠࢃࡿᑓ㛛⫋ࡢேࢆᑐ㇟࡜ࡋࡓࠕ࢚ࣅ

ࢹࣥࢫ࡟ࡶ࡜ࡎ࠸ࡓHIV᳨ᰝ࡟㛵ࡍࡿQ&A㞟ࠖ

ࡢసᡂ࡟ྲྀࡾ⤌ࢇࡔࠋ

᏶ᡂᚋࡣ඲ᅜࡢಖ೺ᡤࡸ≉タ᳨ᰝሙ࡟㓄௜ࡋ ࡓࡾPDF∧ࢆweb࡟ᥖ㍕ࡋࡓࡾࡋ࡚ᐇ㝿࡟౑⏝

ࡋ࡚ࡶࡽ࠸ࠊࡑࡢᚋࠊ࢔ࣥࢣ࣮ࢺㄪᰝࢆ⾜࠺ࡇ࡜

࡛ࠊ౑⏝ឤࡸពぢࡢࣇ࢕࣮ࢻࣂࢵࢡࢆᚓࡓ࠸ࠋ

(3)

F.◊✲Ⓨ⾲

1. ㄽᩥⓎ⾲

1) Yamazaki S, Kondo M, Sudo K, Ueda T, Fujiwara H, Hasegawa N, Kato S. (2016) A Qualitative Real-time PCR assay for HIV-1 and HIV-2 RNA. Japanese Journal of Infectious Diseases. 69:367-372. DOI:

10.7883/yoken.JJID.2015.309

2) Kotani H, Sudo K, Naoki H, Fujiwara H, Hayakawa T, Iketani O, Yamaguchi M, Mochizuki M, Iwata S, Kato S. (2016) Possible involvement of distinct

phylogenetic clusters of HIV-1 variants in the discrepancies between coreceptor tropism predictions based on viral RNA.

Journal of Pharmaceutical Health Care and Sciences.

DOI:10.1186/s40780-016-0065-4

3) Ikeno R, Yamada E, Yamazaki S, Ueda T, Nagata M, Takagi R, Kato S. (2017) Factors contributing to salivary human immunodeficiency virus type-1 levels measured by a Poisson distribution-based PCR method. Journal of International Medical Research.

DOI:10.1177/0300060517728652. e-pub:

November 9, 2017

4) ຍ⸨┿࿃. (2017) 1.1 ච␿ࡢ≉ᚩ. 1.2 ච␿ᢸ ᙜ⣽⬊࡜ჾᐁ㸬 ⮫ᗋච␿᳨ᰝᢏ⾡ᩍᮏ:2-11 5) Yamada E, Takagi R, Tanabe Y, Fujiwara H,

Naoki H, Kato S. (2016) Plasma and saliva concentrations of abacavir, tenofovir, darunavir and raltegravir in

HIV-1-infected patients. International Journal of Clinical Pharmacology and Therapeutics. DOI: 10. 5414/CP202789.

e-pub: April 21, 2017

6) Makiko Kondo, Koji Sudo, Takako Sano, Takuya Kawahata, Ichiro Itoda, Shinya

Iwamuro, Yukihiro Yoshimura, Natsuo Tachikawa, Yoko Kojima, Haruyo Mori, Hiroshi Fujiwara, Naoki Hasegawa, Shingo Kato. (2018) Comparative evaluation of the GeeniusTM HIV 1/2 Confirmatory Assay and the HIV-1 and HIV-2 Western blots in the Japanese population. PLoS One.

13(10):e0198924.doi:10.1371/journal.pone.

0198924. eCollection . Oct 31, 2018.

2.Ꮫ఍Ⓨ⾲

ᒸᓮ⋹Ꮚ㸪ຍ⸨┿࿃㸪ྜྷᮧ࿴ஂࡽ㸬ᅜෆ᪂つ +,9$,'6 デ᩿⑕౛࡟࠾ࡅࡿ⸆๣⪏ᛶ +,9 ࡢ

ືྥ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲

఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬

ᑠ㇂ᐂ㸪ຍ⸨┿࿃㸪㛗㇂ᕝ┤ᶞࡽ㸬157, ࡟ࣛ

ࣝࢸࢢࣛࣅࣝ࠾ࡼࡧࢲࣝࢼࣅࣝࢆྵࡴᙉ໬

⒪ἲࢆᑟධࡋࡓ㸰⑕౛㸬➨ ᅇ᪥ᮏ࢚࢖ࢬ Ꮫ఍Ꮫ⾡㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬 ୸ᒣ⌮ᜨ㸪ຍ⸨┿࿃ࡽ㸬஝⇱ℐ⣬⾑ࢆ⏝࠸ࡓ

+,951$ ᳨ฟἲ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ

⾡㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬 ▮Ọ⏤㔛Ꮚ㸪ຍ⸨┿࿃ࡽ㸬ࠕ⑓㝔࡟ +,9 ᳨ᰝ

ᐇ᪋࢞࢖ࢻࣛ࢖ࣥࠖసᡂ࡜ホ౯ศᯒ࡟ࡘ࠸࡚㸬

➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪㮵 ඣᓥ㸪 ᖺ ᭶㸬

㏆⸨┿つᏊ㸪ຍ⸨┿࿃ࡽ㸬୰ᅜࡢ 060 㛫࡛኱

ὶ⾜ࡋ࡚࠸ࡿ +,9&5)B$(YDULDQWࡢ᪥

ᮏᅜෆ࡬ࡢᣑᩓ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ

⾡㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬 ᫍ㔝ៅ஧㸪ຍ⸨┿࿃ࡽ㸬඲ᅜಖ೺ᡤ࡟࠾ࡅࡿ

ᱵẘ᳨ᰝయไࡢ࢔ࣥࢣ࣮ࢺㄪᰝ㸬➨ ᅇ᪥

ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬

㡲⸨ᘯ஧㸪ຍ⸨┿࿃ࡽ㸬+,9 㒑㏦᳨ᰝ࡟㛵ࡍ

ࡿᐇែㄪᰝ࡜᳨ᰝ⢭ᗘㄪᰝ㸬➨ ᅇ

᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬

ຍ⸨┿࿃㸪㛗㇂ᕝ┤ᶞࡽ㸬&'& ࡀ᥎ዡࡍࡿ +,9

(4)

᳨ᰝᡭ㡰ࡢ᳨ウ࡜ +,9㚷᳨ูᰝ࢟ࢵࢺ

*HHQLXV ࡢ᳨ウ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡

㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬 బ㔝㈗Ꮚ㸪ຍ⸨┿࿃㸪ᕷᕝㄔ୍ࡽ㸬+,9 ᳨ᰝ࣭

┦ㄯ࣐ࢵࣉࢆ⏝࠸ࡓ +,9 ᳨ᰝ┦ㄯ᪋タࡢ᝟ሗ ᥦ౪࠾ࡼࡧࢧ࢖ࢺ฼⏝≧ἣࡢゎᯒ㸬➨ ᅇ

᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪㮵ඣᓥ㸪 ᖺ ᭶㸬

బ㔝㈗Ꮚ㸪㏆⸨┿つᏊ㸪ຍ⸨┿࿃ࡽ㸬᪂つ +,9 ᢠ య ☜ ㄆ ᳨ ᰝ ヨ ⸆ ࡛ ࠶ ࡿ *HHQLXV +,9

&RQILUPDWRU\$VVD\ ࡢ᳨ウ㸬➨ ᅇ᪥ᮏ࢚

࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪ᮾி㒔㸪 ᖺ ᭶㸬

ᕝ⏿ᣅஓ㸪ᑠᓥὒᏊ㸪ຍ⸨┿࿃ࡽ㸬᪂ࡋ࠸ +,9

☜ㄆ᳨ᰝヨ⸆ *HHQLXVτࡢᛶ⬟ホ౯㸬➨ ᅇ

᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪ᮾி㒔㸪 ᖺ ᭶㸬

ྜྷ⏣⦾㸪ຍ⸨┿࿃㸪ྜྷᮧ࿴ஂࡽ㸬 ᖺᗘ +,9 ⸆๣⪏ᛶ᳨ᰝእ㒊⢭ᗘホ౯ࡢሗ࿌㸬➨

ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪ᮾி㒔㸪 ᖺ ᭶㸬

ᒸᓮ⋹Ꮚ㸪ຍ⸨┿࿃㸪ྜྷᮧ࿴ஂࡽ㸬ᅜෆ᪂つ +,9$,'6 デ᩿⑕౛࡟࠾ࡅࡿ⸆๣⪏ᛶ +,9 ࡢ

ືྥ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲

఍㸪ᮾி㒔㸪 ᖺ ᭶㸬

㏆⸨┿つᏊ㸪ຍ⸨┿࿃㸪ྜྷᮧ࿴ஂࡽ㸬᪥ᮏ࡛

ὶ⾜ࡍࡿ +,9&5)B$( ࡜࿘㎶࢔ࢪ࢔ㅖᅜ

࡟࠾ࡅࡿὶ⾜ᰴ࡜ࡢ㛵㐃㸬➨ ᅇ᪥ᮏ࢚࢖

ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪ᮾி㒔㸪 ᖺ

᭶㸬

బ㔝㈗Ꮚ㸪ຍ⸨┿࿃㸪௒஭ගಙࡽ㸬ಖ೺ᡤ➼

බⓗ᳨ᰝᶵ㛵ࢆᑐ㇟࡜ࡋࡓ +,9 ᳨ᰝ┦ㄯయไ

࡟㛵ࡍࡿ࢔ࣥࢣ࣮ࢺㄪᰝ㸬➨ ᅇ᪥ᮏ࢚࢖

ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪ᮾி㒔㸪 ᖺ

᭶㸬

୸ᒣ⌮ᜨ㸪㡲⸨ᘯ஧㸪ຍ⸨┿࿃ࡽ㸬஝⇱ℐ⣬

⾑ࢆ⏝࠸ࡓ +,951$ ࠾ࡼࡧ '1$ ᳨ᰝἲ㸬➨

ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪ᮾி㒔㸪 ᖺ ᭶㸬

㡲⸨ᘯ஧㸪బ㔝㈗Ꮚ㸪ຍ⸨┿࿃ࡽ㸬+,9 㒑㏦

᳨ ᰝ ࡟ 㛵 ࡍ ࡿ ᐇ ែ ㄪ ᰝ ࡜ ᳨ ᰝ ⢭ ᗘ ㄪ ᰝ 㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭

⥲఍㸪ᮾி㒔㸪 ᖺ ᭶㸬

.6XGR76DQR0.RQGR7.DZDKDWD 6.DWRHWDO&RPSDUDWLYH(YDOXDWLRQRI WKH%LR5DG*HHQLXV⁷⁰+,9&RQILUPDWRU\

$VVD\DQGWKH1HZ/$9%ORWDQGLQWKH -DSDQHVH 3RSXODWLRQ WK 5HJLRQDO

&RQJUHVVRIWKH,QWHUQDWLRQDO6RFLHW\RI

%ORRG7UDQVIXVLRQ,6%7*XDQJ]KRXᗈᕞ

&KLQD

㡲⸨ᘯ஧㸪బ㔝㈗Ꮚ㸪㏆⸨┿つᏊ㸪௒஭ගಙ㸪

௒ᮧ㢧ྐ㸪ຍ⸨┿࿃㸬+,9 㒑㏦᳨ᰝ࡟㛵ࡍࡿ

ᐇែㄪᰝ࡜᳨ᰝ⢭ᗘㄪᰝ㸬➨ ᅇ᪥

ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬

㏆⸨┿つᏊ㸪బ㔝㈗Ꮚ㸪㛗ᓥ┿⨾㸪㈆༖೺ᚿ㸪 ᕝ⏿ᣅஓ㸪ຍ⸨┿࿃㸪௒ᮧ㢧ྐ㸬඲ᅜᆅ᪉⾨

⏕◊✲ᡤ࡟࠾ࡅࡿ +,9 ᳨ᰝᐇ᪋≧ἣ㸬➨

ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬

ᅵᒇ⳯Ṍ㸪బ㔝㈗Ꮚ㸪㏆⸨┿つᏊ㸪ሀከᩔᏊ㸪

▼୸㞝஧㸪ᇛᡤᩄⱥ㸪࢚࢝࣋ࢱள▮㸪ᕝ⏿ᣅ ஓ㸪㈆༖೺ᚿ㸪㡲⸨ᘯ஧㸪ຍ⸨┿࿃㸪኱ᮌᖾ Ꮚ㸪௒஭ගಙ㸪௒ᮧ㢧ྐ㸬ಖ೺ᡤ᳨࣭ᰝᡤ࡟

࠾ࡅࡿᱵẘ᳨ᰝᐇ᪋≧ἣ࠾ࡼࡧ㝧ᛶ⋡࡟㛵 ࡍࡿ࢔ࣥࢣ࣮ࢺㄪᰝ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ

఍Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬 ᑠ㇂ᐂ㸪ຍ⸨┿࿃㸪ぶἩ࠶࠸ࡳ㸪㡲⸨ᘯ஧㸪

୸ᒣ⌮ᜨ㸪すᯇ┤⨾㸪Ᏹ㔝ಇ௓㸪ୖ⵿⩏඾㸪

⸨ཎᏹ㸪㛗㇂ᕝ┤ᶞ㸬‽᏶඲㛗ࣉࣟ࢘࢖ࣝࢫ

࡟ࡼࡿ἞⒪ຠᯝࡢ᪂ࡋ࠸ホ౯㸬➨ ᅇ᪥ᮏ

࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬

ᒸᓮ⋹Ꮚ㸪⻏㇂ᩔᏊ㸪బ⸨࠿࠾ࡾ㸪㇏ᔱᓫᚨ㸪 బࠎᮌᝅ㸪ఀ⸨ಇᗈ㸪ᯘ⏣ᗤ⥲㸪ᒸៅ୍㸪₲

Ọ༤அ㸪ྂ㈡㐨Ꮚ㸪㛗ᓥ┿⨾㸪㈆༖೺ᚿ㸪㏆

⸨┿つᏊ㸪᳝㔝⚞୍㑻㸪㡲⸨ᘯ஧㸪ຍ⸨┿࿃㸪

(5)

㇂ཱྀಇᩥ㸪⊦⊁ⱥಇ㸪ᐮᕝᩚ㸪ຍ⸨ⱥ᫂㸪▼ ࣨᆤⰋ᫂㸪୰ᓥ⚽᫂㸪ྜྷ㔝཭♸㸪ኴ⏣ᗣ⏨㸪 ⱱ࿅ᐶ㸪Ώ㑓⌔௦㸪ᯇ⏣ᫀ࿴㸪㔜ぢ㯇㸪ᒾ㇂

㟹㞞㸪ᶓᖥ⬟⾜㸪Ώ㑓኱㸪ᑠᓥὒᏊ㸪᳃἞௦㸪

⸨஭㍤ஂ㸪㧗⏣Ύᘧ㸪༡␃⨾㸪ᒣᮏᨻᘯ㸪ᯇ

ୗಟ୕㸪೺ᒣṇ⏨㸪⸨⏣ḟ㑻㸪ᮡᾆற㸪ྜྷᮧ

࿴ஂ㸪⳥ụṇ㸬ᅜෆ᪂つ +,9$,'6 デ᩿⑕౛

࡟࠾ࡅࡿ⸆๣⪏ᛶ +,9 ࡢືྥ㸬➨ ᅇ᪥

ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬

୸ᒣ⌮ᜨ㸪ຍ⸨┿࿃㸬+,951$ ࡜ '1$ ࡢΰྜ

≀࠿ࡽ 51$ ࢆ㑅ᢥⓗ࡟ቑᖜࡍࡿ 573&5 ἲࡢ 㛤Ⓨ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲

఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬

ᮏ⏣ᚭ㑻㸪ஂឿ┤᫛㸪୸ᒣ⌮ᜨ㸪㡲⸨ᘯ஧㸪 ຍ⸨┿࿃㸬೺ᗣ࡞ +,9 㝧ᛶ⏨ᛶࡀ㝜ᛶዪᛶ࡜

ࡢ㛫࡟Ꮚ౪ࢆᣢࡘࡓࡵ࡟㸸Ὑί⢭Ꮚࢆ⏝࠸ࡓ 㢧ᚤᤵ⢭࡟ࡘ࠸࡚㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍

Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬 ᅵᒇ⳯Ṍ㸪బ㔝㈗Ꮚ㸪㏆⸨┿つᏊ㸪ሀከᩔᏊ㸪

▼୸㞝஧㸪ᇛᡤᩄⱥ㸪࢚࢝࣋ࢱள▮㸪ᕝ⏿ᣅ ஓ㸪㈆༖೺ᚿ㸪㡲⸨ᘯ஧㸪ຍ⸨┿࿃㸪኱ᮌᖾ Ꮚ㸪௒஭ගಙ㸪௒ᮧ㢧ྐ㸬ಖ೺ᡤ᳨࣭ᰝᡤ࡟

࠾ࡅࡿ +,9 ᳨ᰝ࣭┦ㄯᐇ᪋≧ἣ࠾ࡼࡧ㝧ᛶ⋡

࡟㛵ࡍࡿ࢔ࣥࢣ࣮ࢺㄪᰝ㸬➨ ᅇ᪥ᮏ࢚࢖

ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪኱㜰ᗓ㸪 ᖺ

᭶㸬

బ㔝㈗Ꮚ㸪㏆⸨┿つᏊ㸪㡲⸨ᘯ஧㸪௒஭ගಙ㸪 ຍ⸨┿࿃㸪௒ᮧ㢧ྐ㸬Ẹ㛫᳨ᰝࢭࣥࢱ࣮࡟࠾

ࡅࡿ +,9 ᳨ᰝᐇ᪋≧ἣ࡟㛵ࡍࡿ࢔ࣥࢣ࣮ࢺㄪ ᰝ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭⥲఍㸪

኱㜰ᗓ㸪 ᖺ ᭶㸬

29) ᕝ⏿ᣅஓ㸪஭ᡞ⏣୍ᮁ㸪ᑠᓥὒᏊ㸪㏆⸨┿つ Ꮚ㸪㈆༖೺ᚿ㸪బ㔝㈗Ꮚ㸪㡲⸨ᘯ஧㸪㧗⏣᪼㸪㛗ᓥ┿⨾㸪᳃἞௦㸪ຍ⸨┿࿃㸪௒ᮧ㢧ྐ㸬࢚

ࣅࢹࣥࢫ࡟ᇶ࡙࠸ࡓᑓ㛛⫋ྥࡅ +,9 ᳨ᰝ 4 $ 㞟ࡢసᡂ㸬➨ ᅇ᪥ᮏ࢚࢖ࢬᏛ఍Ꮫ⾡㞟఍࣭

⥲఍㸪኱㜰ᗓ㸪 ᖺ ᭶㸬

G.▱ⓗᡤ᭷ᶒࡢྲྀᚓ≧ἣ ≉࡟࡞ࡋࠋ