Day from parturition(Day) - サラブレット種雌馬の生殖周期各ステージにおける内分泌調節機構に関する研究

T e s tos te rone (pg/ ml ) P roge s te rone (ng/ ml )

Fig. 4- 9. Comparing the change in serum concentration of testosterone (ی) with progesterone(ڦ).

Results are expressed as means ± SEM.

㸳❶㸳❶

㸳❶㸳❶ ᡂ⇍㞤ࢧࣛࣈࣞࢵࢻࡢୗᆶయ࣭༸ᕢ࣍ࣝࣔࣥศἪࡢᖺ࿘ᮇⓗኚ໬ᡂ⇍㞤ࢧࣛࣈࣞࢵࢻࡢୗᆶయ࣭༸ᕢ࣍ࣝࣔࣥศἪࡢᖺ࿘ᮇⓗኚ໬ᡂ⇍㞤ࢧࣛࣈࣞࢵࢻࡢୗᆶయ࣭༸ᕢ࣍ࣝࣔࣥศἪࡢᖺ࿘ᮇⓗኚ໬ᡂ⇍㞤ࢧࣛࣈࣞࢵࢻࡢୗᆶయ࣭༸ᕢ࣍ࣝࣔࣥศἪࡢᖺ࿘ᮇⓗኚ໬

㸳㸫㸯㸬ᐇ㦂ࡢ⫼ᬒ 㸳㸫㸯㸬ᐇ㦂ࡢ⫼ᬒ 㸳㸫㸯㸬ᐇ㦂ࡢ⫼ᬒ 㸳㸫㸯㸬ᐇ㦂ࡢ⫼ᬒ

㛗᪥Ꮨ⠇⦾Ṫື≀࡛࠶ࡿ㞤࣐࢘ࡣࠊ᫓࠿ࡽኟࡢ㛗᪥ᮇ࡟༸ᕢᶵ⬟ࡀ㈿ά໬ࡉ

ࢀࠊⓎ᝟ࢆ࿘ᮇⓗ࡟཯᚟ࡍࡿከⓎ᝟ື≀࡛࠶ࡿࠋ࡯࡜ࢇ࡝ࡢ㞤࣐࢘ࡣࠊ▷᪥ᮇ ࡢ ᭶㹼 ᭶࡟༸ᕢᶵ⬟ࡀపୗࡋ࡚ࠊ↓᤼༸࡜࡞ࡿࠋࡋ࠿ࡋࠊẼೃ᮲௳ࡸᰤ㣴

≧ែࠊಶయᕪ࡞࡝࡟ࡼࡾࠊ▷᪥ᮇ࡛ࡶ༸ᕢᶵ⬟ࡀ⥔ᣢࡉࢀࠊⓎ᝟࣭᤼༸ࢆ⧞ࡾ

㏉ࡍ㞤࣐࢘ࡶᏑᅾࡍࡿ࡜ሗ࿌ࡉࢀ࡚࠸ࡿ㸦*LQWKHU%DUU\HWDO㸧ࠋ ࡇࢀࡲ࡛ࠊ㞝ࢧࣛࣈࣞࢵࢻ࡛ࡣࠊどᗋୗ㒊࣭ୗᆶయ࣭⢭ᕢᶵ⬟ࡀᏘ⠇ኚ໬࡟ྠ

ㄪࡋ࡚ࠊྛ✀⏕Ṫ㛵㐃࣍ࣝࣔࣥࡢศἪࡀࢲ࢖ࢼ࣑ࢵࢡ࡟ኚ໬ࡍࡿ஦ᐇࡀ᫂ࡽ࠿

࡟ࡉࢀ࡚࠸ࡿ㸦1DJDWDHWDO'DKNDOHWDO㸧ࠋࡋ࠿ࡋࠊ㞤ࢧࣛࣈ

ࣞࢵࢻ࡟࠾࠸࡚ࡣࠊどᗋୗ㒊࣭ୗᆶయ࣭༸ᕢᶵ⬟ࡀᏘ⠇ኚ໬࡟ྠㄪࡋ࡚ኚ໬ࡍ

ࡿ஦ᐇࢆෆศἪᏛⓗ࡟ヲ⣽࡟᳨ウࡋࡓሗ࿌ࡣᑡ࡞࠸ࠋ

ᮏ◊✲࡛ࡣࠊ᪥ᮏࡢᏘ⠇ኚ໬࡟࠾࠸࡚ࠊ㞤ࢧࣛࣈࣞࢵࢻࡢⓎ᝟࿘ᮇ୰ࠊዷፎࠊ Ἢஙᮇࢆ㏻ࡋࡓ᏶඲⏕Ṫ࿘ᮇ୰ࡢ⏕ṪෆศἪᏛⓗኚ໬ࢆ᫂ࡽ࠿࡟ࡍࡿࡇ࡜ࢆ┠

ⓗ࡜ࡋࡓࠋ

㸳㸫㸰㸬ᮦᩱ࠾ࡼࡧ᪉ἲ 㸳㸫㸰㸬ᮦᩱ࠾ࡼࡧ᪉ἲ㸳㸫㸰㸬ᮦᩱ࠾ࡼࡧ᪉ἲ 㸳㸫㸰㸬ᮦᩱ࠾ࡼࡧ᪉ἲ

㸳㸫㸰㸫㸯㸬౪ヨື≀

ᖺ࠿ࡽ ᖺ࡟ࠊ໭ᾏ㐨ࡢ᪥㧗ᆅ༊࡛㣫㣴ࡉࢀࠊⓎ᝟࣭᤼༸࣭ዷፎ࣭Ἢ ஙࡢ᏶඲⏕Ṫ࿘ᮇࢆ⧞ࡾ㏉ࡋࡓᡂ⇍ࢧࣛࣈࣞࢵࢻ 㢌㸦㹼 ṓ㸧ࢆ⏝࠸ࡓࠋ

࡞࠾ࠊ➨ ❶࡜ྠࡌ࣐࢘ࡀྵࡲࢀ࡚࠸ࡿࠋ

㸳㸫㸰㸫㸰㸬⾑ᾮࡢ᥇ྲྀ࠾ࡼࡧฎ⌮

ᖺ ᭶ ᪥࠿ࡽ ᖺ ᭶ ᪥ࡲ࡛ࠊẖ㐌ࠊ㢁㟼⬦࠿ࡽ࡬ࣃࣜࣥฎ⌮

┿✵᥇⾑⟶㸦ࢸࣝࣔࠊᮾிࠊ᪥ᮏ㸧ࢆ⏝࠸࡚᥇⾑ࡋࡓࠋ

㸳㸫㸰㸫㸱㸬ྛ✀࣍ࣝࣔࣥࡢ ᐃ 㸳㸫㸰㸫㸱㸬ྛ✀࣍ࣝࣔࣥࡢ ᐃ 㸳㸫㸰㸫㸱㸬ྛ✀࣍ࣝࣔࣥࡢ ᐃ 㸳㸫㸰㸫㸱㸬ྛ✀࣍ࣝࣔࣥࡢ ᐃ

➨ ❶࡟グ㏙ࡋࡓ ᐃ᪉ἲࢆ⏝࠸࡚ࠊࣉࣟࣛࢡࢳࣥࠊ㯤యᙧᡂ࣍ࣝࣔࣥ㸦/+㸧ࠊ

༸⬊่⃭࣍ࣝࣔࣥ㸦)6+㸧ࠊࢸࢫࢺࢫࢸࣟࣥࠊ࢚ࢫࢺࣛࢪ࣮࢜ࣝࠊ࢖ࣥࣄࣅࣥࢆ

ࣛࢪ࢜࢖࣒ࣀ࢔ࢵࢭ࢖㸦5,$㸧ἲ࡟࡚ࠊࣉࣟࢪ࢙ࢫࢸࣟࣥࢆ᫬㛫ศゎ⺯ගච␿

ᐃἲ㸦75),$㸧࡟࡚⾑୰⃰ᗘࢆ ᐃࡋࡓࠋ

㸳㸫㸱㸬⤖ᯝ 㸳㸫㸱㸬⤖ᯝ 㸳㸫㸱㸬⤖ᯝ 㸳㸫㸱㸬⤖ᯝ 㸳㸫㸱㸫㸯㸬᏶඲

㸳㸫㸱㸫㸯㸬᏶඲

㸳㸫㸱㸫㸯㸬᏶඲⏕Ṫ⏕Ṫ⏕Ṫ࿘ᮇ⏕Ṫ࿘ᮇ࿘ᮇ࿘ᮇ

㐃⥆ࡋ࡚ ᅇࡢዷፎࢆ⧞ࡾ㏉ࡋࡓ 㢌ࡢ㞤࣐࢘ࡢࣉࣟࣛࢡࢳࣥࠊ/+ࠊ)6+ࠊࣉ

ࣟࢪ࢙ࢫࢸࣟࣥࠊࢸࢫࢺࢫࢸࣟࣥࠊ࢚ࢫࢺࣛࢪ࣮࢜ࣝཬࡧ࢖ࣥࣄࣅࣥࡢ⾑୰⃰

ᗘࢆࠊ)LJ㹼 ࡟♧ࡍࠋ㸦࣐࢘ 1R ࡜ 㸧ࠋ࠸ࡎࢀࡢ࣐࢘ࡶ➨ ᅇ┠࠿

ࡽ ᅇ┠ࡢศፔᚋࡢศፔᚋⓎ᝟࡛㞝࣐࢘࡜஺㓄ࡋ࡚ཷ⫾ࡋ࡚࠸ࡿࠋ࣐࢘ 1R࡛

ࡣࠊ ᅇࡢዷፎඹ࡟ฟ⏘ࡋࡓ௘࣐࢘࡟ᤵஙࡍࡿἪஙᮇዷፎࢆ⤒㐣ࡋ࡚࠸ࡿࠋ࣐࢘

1R ࡛ࡣࠊ➨ ᅇ┠ࡢዷፎࡣࠊ

௘࣐࢘ࡢᤵஙࢆకࢃ࡞࠸༢⊂ዷፎࠊ➨㸰ᅇ┠࡜

ᅇ┠ࡢዷፎࡣࠊἪஙᮇዷፎ࡛࠶ࡗࡓࠋ

㸳㸫㸱㸫㸯㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦㸳㸫㸱㸫㸯㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦㸳㸫㸱㸫㸯㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦

㸳㸫㸱㸫㸯㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦)LJDࠊD㸧

⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡣࠊ࣐࢘ 1R ཬࡧ࣐࢘ 1R

ඹ࡟ࠊᖺ㛫ࢆ㏻ࡋ࡚ࠊ

᭶࠿ࡽ ᭶ࡢ㛗᪥ᮇ࡟㧗್ࢆ♧ࡋࠊ ᭶࠿ࡽ ᭶ࡢ▷᪥ᮇ࡟ࡣࠊప್ࢆ♧ࡋࡓࠋ

ࡲࡓࠊዷፎᮇ࡛ࡣࠊศፔ᫬ᮇ࡟ⴭࡋ࠸㧗್ࢆ♧ࡋࡓࠋ௨ୖࡢ⤖ᯝ࠿ࡽࠊ⾑୰ࣉ

ࣟࣛࢡࢳࣥ⃰ᗘࡣࠊዷፎ࡜ࡣࠊ↓㛵ಀ࡟᪥↷᫬㛫ࡢ㛗࠸᫬ᮇ࡟ศἪࡀୖ᪼ࡍࡿ

Ꮨ⠇ኚ໬࡜ศፔᮇ࡟ⴭࡋࡃୖ᪼ࡍࡿ஧ࡘࡢศἪࣃࢱ࣮ࣥࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸯㸫㸰㸬㸳㸫㸱㸫㸯㸫㸰㸬㸳㸫㸱㸫㸯㸫㸰㸬

㸳㸫㸱㸫㸯㸫㸰㸬/+/+/+㸦/+㸦㸦)LJ㸦)LJ)LJE)LJ EEEࠊࠊࠊEࠊ EEE㸧㸧㸧㸧

⾑୰ /+ ⃰ᗘࡣࠊ࣐࢘ 1R ࡜࣐࢘ 1R

ඹ࡟ࠊ➨ ᅇ┠ࡢዷፎࡢ๓࡟ ᅇࡢ

Ⓨ᝟࿘ᮇࡀ⧞ࡾ㏉ࡉࢀ࡚࠾ࡾࠊ࠸ࡎࢀࡢⓎ᝟࿘ᮇ࡛ࡶ /+ ࢧ࣮ࢪࡀほᐹࡉࢀࡓࠋ ᅇ┠࡜ ᅇ┠ࡢዷፎ࡛ࡣࠊศፔᚋ᤼༸࡛ዷፎࡋ࡚࠾ࡾࠊศፔᚋ࡟ ᅇࡢ /+ ࢧ

࣮ࢪࡀほᐹࡉࢀࡓࠋዷፎᮇ࡛ࡣࠊ࠸ࡎࢀࡢ࣐࡛࢘ࡶࠊዷፎ 㐌࠿ࡽ 㐌ࡢᮇ 㛫ࠊ⾑୰ /+ ⃰ᗘࡀⴭࡋ࠸㧗್ࢆ♧ࡋࡓࠋࡇࡢዷፎ๓ᮇ࡟⾑୰࡟ⴭࡋࡃୖ᪼ࡍࡿ

/+ ࡣࠊ ᐃ࡟౑⏝ࡋࡓ࣐࢘ /+

ᢠయ࡜஺ᕪ཯ᛂࢆ♧ࡍ࣐࢘⤧ẟᛶᛶ⭢่⃭࣍ࣝࣔ

ࣥ㸦H&*㸧࡜ุ᩿ࡉࢀࡓࠋ࠸ࡎࢀࡢዷፎ࡛ࡶࠊዷፎ ᪥௨㝆ࡣࠊ⾑୰ /+ ⃰ᗘ

ࡣࠊᇶᗏ್ࢆ⥔ᣢࡋࡓࠋ

㸳㸫㸱㸫㸯㸫㸱㸬㸳㸫㸱㸫㸯㸫㸱㸬㸳㸫㸱㸫㸯㸫㸱㸬

㸳㸫㸱㸫㸯㸫㸱㸬)6+)6+)6+㸦)6+㸦㸦)LJ㸦)LJ)LJ)LJFFFࠊFࠊࠊFࠊ FFF㸧㸧㸧㸧

⾑୰ )6+ ⃰ᗘࡣࠊࣉࣟࣛࢡࢳࣥ࡜㢮ఝࡋࡓኚ໬ࢆ♧ࡋࡓࠋࡍ࡞ࢃࡕࠊ᪥↷᫬

㛫ࡢ㛗࠸㛗᪥ᮇ࡟㧗ࡃ㸪▷᪥ᮇ࡟ప࠸ኚ໬ࢆ♧ࡋࡓࠋ࣐࢘ 1R ࡀࠊ࣐࢘ 1R

ࡼࡾࡶ඾ᆺⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋዷፎᮇ࡟ࡣࠊ⾑୰ )6+ ⃰ᗘࡣ H&* ࡢศἪ᫬ᮇ࡜

ྠ᫬ᮇ࡟㧗್ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸯㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸯㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸯㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦

㸳㸫㸱㸫㸯㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦)LJ)LJ)LJ)LJGGGGࠊࠊࠊࠊGGGG㸧㸧㸧㸧

⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊ࣐࢘ 1R ࡜࣐࢘ 1R

ඹ࡟ ᅇࡢዷፎᮇ࡟ࡣࠊ

ศፔᚋ᤼༸ࡢᚋࡢ㯤యᮇ࡟ୖ᪼ࡋࠊዷፎ ᪥㡭࡟୍ᗘపୗࡋࡓᚋዷፎ๓༙ᮇࡢ H&* ศἪ᫬ᮇ࡟ⴭࡋࡃୖ᪼ࡋࠊዷፎᚋ༙ᮇ࡟ࡣࠊ

ᇶᗏ್ࢆ⥔ᣢࡋ࡚ศፔ๓࡟ᛴୖ

᪼ࡍࡿ඾ᆺⓗ࡞ศἪࣃࢱ࣮ࣥࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸯㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸯㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸯㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦

㸳㸫㸱㸫㸯㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦)LJ)LJ)LJ)LJHHHHࠊࠊࠊࠊHHHH㸧㸧㸧㸧

⾑୰ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘࡣࠊࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜㢮ఝࡋࡓኚ໬ࢆ♧ࡋࡓࠋ࢘

࣐ 1R ࡜࣐࢘ 1R

ඹ࡟ࠊ ᅇ┠ࡢዷፎ๓ࡢⓎ᝟࿘ᮇ࡟ࡣࠊࣉࣟࢪ࢙ࢫࢸࣟࣥ

࡜ྠᵝ࡟㯤యᮇ࡟㧗ࡃࠊཷ⫾ᚋࡣࠊዷፎ඲ᮇ㛫ࢆ㏻ࡋ࡚ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜㢮

ఝࡢศἪࣃࢱ࣮ࣥࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸯㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦㸳㸫㸱㸫㸯㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦㸳㸫㸱㸫㸯㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦

㸳㸫㸱㸫㸯㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦)LJV)LJV)LJV)LJVIIIIࠊࠊࠊࠊIIII㸧㸧㸧㸧

⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡣࠊ࣐࢘ 1R ࡜࣐࢘ 1R

ඹ࡟ ᅇࡢዷፎᮇ࡟ࡣࠊ

ዷፎᚋ༙ᮇࡢዷፎ 㐌࠿ࡽ 㐌ࡲ࡛ⴭࡋ࠸㧗್ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸯㸫㸵㸬࢖ࣥࣄࣅࣥ㸦㸳㸫㸱㸫㸯㸫㸵㸬࢖ࣥࣄࣅࣥ㸦㸳㸫㸱㸫㸯㸫㸵㸬࢖ࣥࣄࣅࣥ㸦

㸳㸫㸱㸫㸯㸫㸵㸬࢖ࣥࣄࣅࣥ㸦)LJ)LJ)LJ)LJJJJࠊJࠊࠊࠊJJJJ㸧㸧㸧㸧

⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡣࠊ࣐࢘ 1R ࡜࣐࢘ 1R

ඹ࡟ ᅇࡢዷፎᮇ࡟ࡣࠊዷፎ ๓༙ᮇ࡟㧗ࡃࠊዷፎᚋ༙ᮇ࡟ప࠸ኚ໬ࢆ♧ࡋࡓࠋ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡣࠊዷፎ ᮎᮇࡢศፔ๓࡟ࡣࠊ᫂ࡽ࠿࡟ୖ᪼ࡋ࡚ศፔᚋ᤼༸ࡲ࡛ୖ᪼ࡋࠊ᤼༸ᚋపୗࡋࡓࠋ

㸳㸫㸱㸫㸰㸬㠀ዷፎᮇ 㸳㸫㸱㸫㸰㸬㠀ዷፎᮇ 㸳㸫㸱㸫㸰㸬㠀ዷፎᮇ 㸳㸫㸱㸫㸰㸬㠀ዷፎᮇ

ศፔᚋḟᅇࡢዷፎࡲ࡛ࠊ✵⫾࡛Ἢஙࢆ⾜ࡗ࡚࠸࡞࠸㞤ࢧࣛࣈࣞࢵࢻ 㢌㸦࢘

࣐ 1Rࠊࠊࠊ㸧ཬࡧ㞳ஙᚋ✵⫾࡛Ἢஙࢆ⾜ࡗ࡚࠸࡞࠸㞤ࢧࣛࣈࣞࢵࢻ 㢌㸦࣐࢘ 1R㸧ࡢྜィ㢌ࡢ⣙ ᖺ㛫ࡢ㠀ዷፎᮇࡢ⾑୰ࣉࣟࣛࢡࢳࣥࠊ/+ࠊ)6+ࠊ

ࣉࣟࢪ࢙ࢫࢸࣟࣥࠊࢸࢫࢺࢫࢸࣟࣥࠊ࢚ࢫࢺࣛࢪ࣮࢜ࣝཬࡧ࢖ࣥࣄࣅࣥ⃰ᗘࡢ ኚ໬ࢆ᳨ウࡋࡓࠋ㸦㸦㸦㸦)LJࠊࠊࠊ㸧

㸳㸫㸱㸫㸰㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦㸳㸫㸱㸫㸰㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦㸳㸫㸱㸫㸰㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦

㸳㸫㸱㸫㸰㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦)LJDࠊDࠊDࠊD㸧

⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡣࠊ࣐࢘ 1R

ඹ࡟ࠊ ᭶࠿ࡽ ᭶ࡢ㛗᪥ᮇ࡟

㧗್ࢆ♧ࡋࠊ▷᪥ᮇࡢ ᭶࠿ࡽ ᭶࡟ࡣࠊప್ࢆ♧ࡍ᪥↷᫬㛫ࡢ㛗ࡉ࡜୍⮴ࡋ ࡓኚ໬ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸰㸫㸰㸬㸳㸫㸱㸫㸰㸫㸰㸬㸳㸫㸱㸫㸰㸫㸰㸬

㸳㸫㸱㸫㸰㸫㸰㸬/+/+/+㸦/+㸦㸦)LJ㸦)LJ)LJE)LJ EEEࠊࠊࠊEࠊ EEࠊEࠊࠊࠊEEEEࠊࠊࠊࠊEEEE㸧㸧㸧㸧

⾑୰ /+ ⃰ᗘࡣࠊ᪥↷᫬㛫ࡢ㛗࠸㛗᪥ᮇ࡟ࡣࠊ࿘ᮇⓗ࡞ୖ᪼࡜ୗ㝆ࢆ⧞ࡾ㏉ࡋ ࡓࡀࠊ▷᪥ᮇ࡟ࡣࠊᇶᗏࣞ࣋ࣝࢆ♧ࡋࡓࠋ࣐࢘ 1R)LJE࡛ࡣࠊ⾑୰ /+

⃰ᗘࡣ ᭶࠿ࡽ ᭶ࡲ࡛ࠊ࿘ᮇⓗ࡞ୖ᪼࡜ୗ㝆ࢆ⧞ࡾ㏉ࡋࡓࠋ ᭶࠿ࡽ ᭶

࡟ࡣࠊ⾑୰ /+ ⃰ᗘࡣᇶᗏ್ࢆ♧ࡋࡓࠋ࣐࢘ 1R

)LJE࡛ࡣࠊ ௘㤿ࢆ㞳ங ᚋࠊ ᭶࠿ࡽ ᭶࡟ࡣࠊᇶᗏࣞ࣋ࣝࢆ♧ࡋࡓࡀࠊ ᭶࠿ࡽ ᭶࡟ࡣࠊ୙つ๎࡞

ୖ᪼࡜ୗ㝆ࢆ⧞ࡾ㏉ࡋࡓࠋ࣐࢘ 1R )LJE࡛ࡣࠊ ᭶࠿ࡽ ᭶࡟ࡣࠊ

࿘ᮇⓗ࡞ୖ᪼࡜ୗ㝆ࢆ⧞ࡾ㏉ࡋࡓࡀࠊ ᭶࠿ࡽ ᭶࡟ࡣࠊ

ᇶᗏࣞ࣋ࣝࢆ♧ࡋࡓࠋ

࣐࢘ 1R

)LJE࡛ࡣࠊ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ࿘ᮇⓗ࡞ୖ᪼࡜ୗ㝆ࢆ⧞

ࡾ㏉ࡋࡓࠋ

㸳㸫㸱㸫㸰㸫㸱㸬㸳㸫㸱㸫㸰㸫㸱㸬㸳㸫㸱㸫㸰㸫㸱㸬

㸳㸫㸱㸫㸰㸫㸱㸬)6+)6+)6+㸦)6+㸦㸦)LJ㸦)LJ)LJ)LJFFFࠊFࠊࠊFࠊ FFFࠊࠊࠊࠊFFFFࠊࠊࠊࠊFFF㸧F㸧㸧㸧

⾑୰ )6+ ⃰ᗘࡣࠊ⾑୰ /+ ⃰ᗘ࡜ࡣ␗࡞ࡾࠊ࿘ᮇⓗኚ໬ࡀ೵Ṇࡋࡓࡢࡣࠊ࣐࢘

1R㸦㸦㸦㸦)LJVF㸧ࡢ ᭶࠿ࡽ ᭶ࡢࡳ࡛ࠊ௚ࡢ࣐࡛࢘ࡣࠊほᐹᮇ㛫୰࡟ࡣࠊ

࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸰㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸰㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸰㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦

㸳㸫㸱㸫㸰㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦)LJV)LJV)LJV)LJVGGGGࠊࠊࠊࠊGGGGࠊࠊࠊࠊGGGࠊGࠊࠊGࠊ GGG㸧㸧㸧㸧

⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊ᤼༸ᚋࡢ㯤యᮇ࡟㧗್ࢆ♧ࡋࡓࠋ࣐࢘ 1R㸦㸦㸦㸦)LJ G㸧࡛ࡣࠊほᐹࡋࡓ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ⧞ࡾ㏉ࡋࡓࠋ࣐࢘

1R㸦㸦㸦㸦)LJG㸧࡛ࡣࠊ㞳ஙᚋ⾑୰ /+ ⃰ᗘࡀ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡉ࡞࠿ࡗࡓ

᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡀ୙つ๎࡞ኚ໬ࢆ♧ࡋࠊ ᭶࠿ࡽ

᭶ࡢ㛫ࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊ

ᇶᗏ್ࢆ⥔ᣢࡋࠊ᤼༸ࡀ೵Ṇࡋࡓ࡜

᥎ᐃࡉࢀࡓࠋ࣐࢘ 1R㸦

㸦㸦)LJG㸧࡛ࡣࠊ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ⾑୰ࣉࣟࢪ㸦

࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࡀࠊ⾑୰ /+ ⃰ᗘࡀᇶᗏ್ࢆ♧ࡋࡓ

᭶࠿ࡽ ᭶ࡢ㛫ࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡶᇶᗏ್ࢆ♧ࡋࠊ᤼༸ࡀ೵Ṇࡋ ࡓ࡜᥎ᐃࡉࢀࡓࠋ࣐࢘ 1R㸦㸦㸦㸦)LJG㸧࡛ࡣࠊ

ほᐹࡋࡓ ᭶࠿ࡽ ᭶ࡢ㛫ࡣࠊ

⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸰㸫㸳㸬ࢸࢫࢺࢫࢸࣟࢺࣥ㸦㸳㸫㸱㸫㸰㸫㸳㸬ࢸࢫࢺࢫࢸࣟࢺࣥ㸦㸳㸫㸱㸫㸰㸫㸳㸬ࢸࢫࢺࢫࢸࣟࢺࣥ㸦

㸳㸫㸱㸫㸰㸫㸳㸬ࢸࢫࢺࢫࢸࣟࢺࣥ㸦)LJ)LJ)LJ)LJHHHHࠊࠊࠊࠊHHHHࠊࠊࠊࠊHHHࠊHࠊࠊHࠊ HHH㸧㸧㸧㸧

⾑୰ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘࡣࠊほᐹࡋࡓ 㢌ࡢ࣐࢘ඹ࡟⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ

⃰ᗘࡢኚ໬࡜ᖹ⾜ࡋࡓኚ໬ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸰㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦㸳㸫㸱㸫㸰㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦㸳㸫㸱㸫㸰㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦

㸳㸫㸱㸫㸰㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦)LJV)LJV)LJV)LJVIIIIࠊࠊࠊࠊIIIIࠊࠊࠊࠊIIIࠊIࠊࠊIࠊ III㸧㸧㸧㸧⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡶᖺ㛫ࢆ㏻ࡋ࡚࿘ᮇⓗ࡞ୖ᪼࡜ୗ㝆ࡢኚ໬ࢆ♧

ࡋࡓࠋ࣐࢘ 1R㸦㸦㸦㸦)LJVI㸧࡛ࡣࠊほᐹᮇ㛫ࡢ ᭶࠿ࡽ ᭶ࡢ㛫⾑୰࢚ࢫࢺ

ࣛࢪ࣮࢜ࣝ⃰ᗘࡢࣆ࣮ࢡࣞ࣋ࣝ࡟ࡣᕪࡀぢࡽࢀࡓࡀ࿘ᮇⓗኚ໬ࢆ♧ࡋࡓࠋ࣐࢘

1R 㸦㸦㸦㸦)LJVI㸧࡛ࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡀᇶᗏ್ࢆ♧ࡋࡓ ᭶

࠿ࡽ ᭶ࡲ࡛ࡣࠊᇶᗏ್ࢆ♧ࡋ࡚᤼༸ࡢ೵Ṇࡀ❚ࢃࢀࡓࡀࠊ ᭶࠿ࡽ ᭶࡟ࡣ

⾑୰⃰ᗘࡀୖ᪼ࡋࡓࠋ࣐࢘ 1R㸦㸦㸦㸦)LJVI㸧࡛ࡣࠊ⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰

ᗘࡣࠊ ᭶࠿ ᭶ࡲ࡛ࡣ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࡀࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘ ࡀᇶᗏ್ࢆ♧ࡋࡓ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡶᇶᗏ್ࢆ

♧ࡋࡓࠋ࣐࢘ 1R㸦㸦㸦㸦)LJVI㸧࡛ࡣࠊ⾑୰⃰ᗘ࡟㐪࠸ࡣ࠶ࡗࡓࡀࠊほᐹᮇ㛫

୰ࡣࠊ⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋ ᭶࠿ࡽ ᭶࡟ࡣࠊ

ⴭࡋ࠸㧗್ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸰㸫㸵㸬࢖ࣥࣄࣅࣥ㸦㸳㸫㸱㸫㸰㸫㸵㸬࢖ࣥࣄࣅࣥ㸦㸳㸫㸱㸫㸰㸫㸵㸬࢖ࣥࣄࣅࣥ㸦

㸳㸫㸱㸫㸰㸫㸵㸬࢖ࣥࣄࣅࣥ㸦)LJ)LJ)LJ)LJJJJࠊJࠊࠊࠊJJJJࠊࠊࠊࠊIIIIࠊࠊࠊIࠊ II㸧I㸧㸧㸧

⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡣࠊᖺ㛫ࢆ㏻ࡋ࡚࿘ᮇⓗ࡞ୖ᪼࡜ୗ㝆ࡢኚ໬ࢆ♧ࡋࡓࠋ

࣐࢘ 1R㸦)LJJ㸧࡛ࡣࠊほᐹᮇ㛫ࡢ ᭶࠿ࡽ ᭶ࡲ࡛ୖ᪼࡜ୗ㝆ࡢ࿘ᮇ

ⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋ࣐࢘ 1R㸦)LJJ㸧࡛ࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡀ

ᇶᗏ್ࢆ♧ࡋࡓ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡶᇶᗏ್ࢆ♧ࡋࡓࡀࠊ

᭶௨㝆࿘ᮇⓗኚ໬ࢆ♧ࡋࡓࠋ ᭶࠿ࡽ ᭶࡟ࡣࠊࣆ࣮ࢡ್ࡀ㧗್ࢆ♧ࡋࡓࠋ࢘

࣐ 1R㸦)LJJ㸧࡛ࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡀ࿘ᮇⓗኚ໬ࢆ♧ࡋ࡚࠸

ࡿ ᭶࠿ࡽ ᭶ࡲ࡛ࡣ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡶࣆ࣮ࢡ್࡟ࡣᕪࡀㄆࡵࡽࢀࡿࡀ࿘

ᮇⓗ࡞ኚ໬ࢆ♧ࡋࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡀᇶᗏ್ࢆ♧ࡋࡓ ᭶࠿ࡽ ᭶

ࡲ࡛ࡣࠊ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡶᇶᗏ್ࢆ♧ࡋࡓࠋ࣐࢘ 1R㸦)LJJ㸧࡛ࡣࠊ ᭶࠿ࡽ ᭶ࡢほᐹᮇ㛫୰ࡣࠊ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸱㸬Ἢஙᮇ 㸳㸫㸱㸫㸱㸬Ἢஙᮇ 㸳㸫㸱㸫㸱㸬Ἢஙᮇ 㸳㸫㸱㸫㸱㸬Ἢஙᮇ

࣐࢘ 1Rࠊࠊࠊࠊ㸦㸦㸦㸦)LJࠊࠊࠊࠊ㸧࡛ࡣࠊዷፎࢆక

ࢃ࡞࠸Ἢஙᮇࡀほᐹࡉࢀࡓࠋࡲࡓࠊ࣐࢘ 1Rࠊࠊࠊ

㸦㸦㸦㸦)LJࠊࠊࠊ 㸧࡛ࡣࠊዷፎࢆకࡗࡓἪஙᮇࡀほᐹࡉࢀࡓࠋ

㸳㸫㸱㸫㸱㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦㸳㸫㸱㸫㸱㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦㸳㸫㸱㸫㸱㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦

㸳㸫㸱㸫㸱㸫㸯㸬ࣉࣟࣛࢡࢳࣥ㸦)LJ)LJ)LJD)LJ DDࠊDࠊࠊDࠊ DDࠊDࠊࠊDࠊ DDࠊDࠊࠊDࠊ DDࠊDࠊࠊDࠊ DDࠊDࠊࠊࠊDDDDࠊࠊࠊࠊ DDDDࠊࠊࠊࠊDDDࠊDࠊࠊDࠊ DDD㸧㸧㸧㸧

⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡣࠊ ᭶࠿ࡽ ᭶ࡢ㛗᪥ᮇ࡟㧗್ࢆ♧ࡋࡓࠋ㛗᪥ᮇ࡟⾑

୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡀୖ᪼ࡍࡿഴྥࡣࠊἪங༢⊂ࡢሙྜ࡟ࡶዷፎ࡜Ἢஙࡀྠ᫬

࡟㐍⾜ࡋ࡚࠸ࡿሙྜ࡟ࡶྠᵝ࡛࠶ࡗࡓࠋ

㸳㸫㸱㸫㸱㸫㸰㸬㸳㸫㸱㸫㸱㸫㸰㸬㸳㸫㸱㸫㸱㸫㸰㸬

㸳㸫㸱㸫㸱㸫㸰㸬/+/+/+㸦/+㸦㸦)LJ㸦)LJ)LJ)LJEEEࠊEࠊࠊࠊEEEEࠊࠊࠊࠊEEEEࠊࠊࠊEࠊ EEࠊEࠊࠊEࠊ EEEࠊࠊࠊࠊEEEEࠊࠊࠊࠊEEEࠊEࠊࠊEࠊ EEEࠊࠊࠊࠊ EEEE㸧㸧㸧㸧

⾑୰ /+ ⃰ᗘࡣࠊἪஙᮇ㛫୰ࡶ ᭶࠿ࡽ ᭶ࡢ㛗᪥ᮇ࡟ࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ

♧ࡋࡓ㸦㸦㸦㸦)LJEࠊEࠊEࠊEࠊE㸧ࠋዷፎࡋࡓሙྜ࡟ࡣࠊH&* ࡢኚ

໬࡜㔜࡞ࡾࠊୗᆶయᛶࡢෆᅉᛶࡢ /+ ࡢኚ໬ࡣࠊゎᯒ୙⬟࡛࠶ࡗࡓ㸦)LJEࠊ EࠊEࠊE㸧ࠋ

㸳㸫㸱㸫㸱㸫㸱㸬㸳㸫㸱㸫㸱㸫㸱㸬㸳㸫㸱㸫㸱㸫㸱㸬

㸳㸫㸱㸫㸱㸫㸱㸬)6+)6+)6+㸦)6+㸦㸦)LJ㸦)LJ)LJF)LJ FFࠊFࠊࠊࠊFFFFࠊࠊࠊࠊFFFFࠊࠊࠊࠊFFFࠊFࠊࠊFࠊ FFࠊFࠊࠊࠊFFFFࠊࠊࠊࠊFFFFࠊࠊࠊFࠊ FFࠊFࠊࠊࠊ FFFF㸧㸧㸧㸧

⾑୰ )6+ ⃰ᗘࡣࠊἪஙᮇ㛫୰ࡶ㛗᪥ᮇ࡟ࡣࠊ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓ㸦)LJFࠊ FࠊFࠊFࠊF㸧ࠋ⾑୰ )6+ ⃰ᗘࡣࠊዷፎࡋࡓሙྜ࡟ࡶࠊH&* ࡢศἪኚ

໬࡟ᙳ㡪ࡉࢀࡎ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓ㸦)LJFࠊFࠊFࠊF㸧ࠋ

㸳㸫㸱㸫㸱㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸱㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸱㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦

㸳㸫㸱㸫㸱㸫㸲㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ㸦)LJ)LJ)LJ)LJGGGࠊGࠊࠊࠊGGGࠊGࠊࠊGࠊ GGGࠊࠊࠊࠊGGGࠊGࠊࠊࠊGGGࠊGࠊࠊࠊ GGGGࠊࠊࠊࠊGGGࠊGࠊࠊGࠊ GGGࠊࠊࠊࠊGGGG㸧㸧㸧㸧

⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊἪஙᮇ࡛ࡶ㛗᪥ᮇ࡟ࡣ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࠊ

᤼༸ࡀ㉳ࡇࡗ࡚࠸ࡿ࡜ุ᩿ࡉࢀࡓࠋዷፎࡋࡓሙྜ࡟ࡣࠊ᤼༸ࡣࠊ೵Ṇࡍࡿࡀዷ ፎ๓༙ᮇࡣࠊH&* ࡢ่⃭࡟ࡼࡾ๪㯤య࠿ࡽศἪࡉࢀࡓࣉࣟࢪ࢙ࢫࢸࣟࣥ࡟ࡼࡾࠊ

⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣⴭࡋࡃୖ᪼ࡋࡓ㸦)LJGࠊGࠊGࠊG㸧ࠋ

㸳㸫㸱㸫㸱㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸱㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦㸳㸫㸱㸫㸱㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦

㸳㸫㸱㸫㸱㸫㸳㸬ࢸࢫࢺࢫࢸࣟࣥ㸦)LJ)LJ)LJ)LJHHHࠊHࠊࠊHࠊ HHHࠊࠊࠊࠊHHHHࠊࠊࠊHࠊ HHHࠊࠊࠊࠊHHHHࠊࠊࠊࠊHHHࠊHࠊࠊࠊ HHHHࠊࠊࠊࠊHHHࠊHࠊࠊHࠊ HHH㸧㸧㸧㸧

⾑୰ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘࡣࠊἪஙᮇ࡛ࡶ㛗᪥ᮇ࡟ࡣ࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࠊ⾑

୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡢኚ໬࡜ᖹ⾜ࡋࡓኚ໬ࢆ♧ࡋࡓࠋ

㸳㸳

㸳㸳㸫㸱㸫㸱㸫㸴㸫㸱㸫㸱㸫㸴㸫㸱㸫㸱㸫㸴㸫㸱㸫㸱㸫㸴㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦)LJ㸬࢚ࢫࢺࣛࢪ࣮࢜ࣝ㸦)LJ)LJ)LJIIIࠊIࠊࠊࠊIIIࠊIࠊࠊIࠊ IIIࠊࠊࠊࠊIIIࠊIࠊࠊࠊIIIࠊIࠊࠊࠊ IIIIࠊࠊࠊࠊIIIࠊIࠊࠊIࠊ IIIࠊࠊࠊࠊIIII㸧㸧㸧㸧

⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡣࠊἪங୰࡛ࡶ㛗᪥ᮇ࡛࿘ᮇⓗ࡞ኚ໬ࢆ♧ࡋࡓࠋ

㸳㸳

㸳㸳㸫㸱㸫㸱㸫㸵㸫㸱㸫㸱㸫㸵㸫㸱㸫㸱㸫㸵㸫㸱㸫㸱㸫㸵㸬࢖ࣥࣄࣅࣥ㸦㸬࢖ࣥࣄࣅࣥ㸦㸬࢖ࣥࣄࣅࣥ㸦㸬࢖ࣥࣄࣅࣥ㸦)LJ)LJ)LJJ)LJ JJJࠊࠊࠊࠊJJJࠊJࠊࠊࠊJJJࠊJࠊࠊJࠊ JJJࠊࠊࠊࠊJJJࠊJࠊࠊࠊJJJࠊJࠊࠊࠊ JJJJࠊࠊࠊࠊJJJࠊJࠊࠊJࠊ JJJ㸧㸧㸧㸧

⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡣࠊศፔ๓࠿ࡽୖ᪼ࡋࡓศፔᚋ᤼༸࡟ྥࡅ࡚ࣆ࣮ࢡࢆ♧

ࡍኚ໬ࢆ♧ࡋࡓࠋἪங୰࡛ࡶ㛗᪥ᮇ࡟࿘ᮇⓗ࡞᤼༸࡟కࡗ࡚᤼༸๓࡟ୖ᪼ࡍࡿ

ኚ໬ࢆ♧ࡋࡓࠋࡇࡢ㸳㸫㸱㸫㸱㸬Ἢஙᮇ㸦)LJࠊࠊࠊࠊ㸧ࡢ ศἪኚ໬ࡣࠊἪஙᮇዷፎࡢሙྜ࡟ࡶྠᵝ࡛࠶ࡗࡓࠋ

㸳㸫㸱㸫㸳㸫㸱㸫

㸳㸫㸱㸫㸳㸫㸱㸫㸬ὶ⏘ᚋࡢ࣍ࣝࣔࣥศἪኚ໬㸦㸬ὶ⏘ᚋࡢ࣍ࣝࣔࣥศἪኚ໬㸦㸬ὶ⏘ᚋࡢ࣍ࣝࣔࣥศἪኚ໬㸦㸬ὶ⏘ᚋࡢ࣍ࣝࣔࣥศἪኚ໬㸦)LJ)LJ)LJ)LJ ࠊࠊࠊࠊ㸧㸧㸧㸧

࣐࢘ 1R ࡣࠊศፔᚋ᤼༸࡛✀㞝㤿࡜஺㓄ࡋ࡚ཷ⫾ࡋἪஙᮇዷፎ୰ࡢ ᭶࡟

ዷፎ ᪥࡛ὶ⏘ࡋࡓࠋ

⩣ᖺࡢ ᭶࡟✀㞝㤿࡜஺㓄ࡋ࡚ཷ⫾ࡋṇᖖ࡟ศፔࡋࡓࠋ

⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡣࠊὶ⏘ᚋࡢ▷᪥ᮇ࡟ࡣࠊప್࡛⤒㐣ࡋࠊḟᖺࡢ㛗᪥ᮇ

࡟ୖ᪼ࢆ♧ࡋࡓࡀୖ᪼ࡋࡓࣞ࣋ࣝࡣࠊ๓ᖺ࡟ẚ࡭࡚ప࠿ࡗࡓࠋ⾑୰ /+ ⃰ᗘࡣࠊ ᭶࡟ὶ⏘ᚋ ᭶ࡲ࡛ ᅇࡢ࿘ᮇⓗࢧ࣮ࢪࡀㄆࡵࡽࢀࠊ ᭶ࡲ࡛ᇶᗏ್ࢆ⥔ᣢ ࡋࠊ ᭶ࡢ᤼༸࡛ཷ⫾ࡋࡓࠋ⾑୰ )6+ ⃰ᗘࡣࠊὶ⏘ᚋࡶ࿘ᮇⓗ࡞ศἪࢆ♧ࡋࡓࠋ

⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊὶ⏘ᚋࡶ࿘ᮇⓗศἪࢆ♧ࡋࡓࡀࠊ ᭶࠿ࡽ ᭶

ࡲ࡛ࡣࠊ㧗್ࡢࡲࡲ⤒㐣ࡋࡓࠋ⾑୰ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘࡣࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸ

ࣟࣥ⃰ᗘ࡜ྠᵝࡢኚ໬ࢆ♧ࡋࡓࠋ⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡣࠊὶ⏘ᚋ⩣ᖺࡢ

ཷ⫾ࡲ࡛ᇶᗏ್࡛⤒㐣ࡋࡓࠋ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡣࠊὶ⏘ᚋࡶᇶᗏ್ࢆ⥔ᣢࡋ

࡚ࠊศፔ๓ᚋ࡟ㄆࡵࡽࢀࡿୖ᪼ࡣ࡞࠿ࡗࡓࠋ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊప್࡟పୗ

ࡋࠊ ᭶௨㝆ࡣࠊ෌ࡧ࿘ᮇⓗኚ໬ࢆ♧ࡋࡓࠋ

࣐࢘ 1R ࡣࠊศፔᚋ᤼༸࡛✀㞝㤿࡜஺㓄ࡋࡓࡀཷ⫾ࡏࡎ ᖺ㛫✵⫾ࡢࡲࡲ

Ἢஙᮇࢆ⤒࡚ࠊ

⩣ᖺ ᭶࡟ཷ⫾ࡋࡓࡀࠊ ᭶ዷፎ ࣨ᭶࡛ὶ⏘ࡋࠊ ෌ࡧ ᖺ㛫✵

⫾࡛⤒㐣ࡋࡓ౛࡛࠶ࡿࠋ⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡣࠊ ᭶࡟ὶ⏘ᚋ

᭶ࡲ࡛ୖ᪼ࡋ ࡓࡀࠊ

ࣆ࣮ࢡࣞ࣋ࣝࡣࠊ ๓ᅇࡢṇᖖศፔ࡜ẚ㍑ࡍࡿ࡜ప࠸್࡛࠶ࡗࡓࠋ ᭶࠿ࡽ

⩣ᖺࡢ ᭶ࡲ࡛ᇶᗏ್࡛⤒㐣ࡋࠊ㛗᪥ᮇ࡟ࡶ᫂ࡽ࠿࡞ୖ᪼ࡣㄆࡵࡽࢀ࡞࠿ࡗࡓࠋ

⾑୰ /+ ⃰ᗘࡣࠊ ᭶࡟ὶ⏘ᚋ ᭶ࡲ࡛࿘ᮇⓗࢧ࣮ࢪࡀㄆࡵࡽࢀࡓࡀࠊ ᭶࠿

ࡽ ᭶ࡲ࡛ᇶᗏ್ࢆ⥔ᣢࡋࠊ ᭶࠿ࡽ෌ࡧ࿘ᮇⓗ࡞ศἪࢆ♧ࡋࡓࠋ⾑୰ )6+ ⃰ᗘ ࡣࠊὶ⏘ᚋࡶࣆ࣮ࢡࣞ࣋ࣝ࡟ᕪࡣ࠶ࡿࡀ࿘ᮇⓗ࡞ศἪࢆ♧ࡋࡓࠋ⾑୰ࣉࣟࢪ࢙

ࢫࢸࣟࣥ⃰ᗘࡣࠊὶ⏘ᚋࡶ࿘ᮇⓗศἪࢆ♧ࡋࡓࡀࠊ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ㧗್

ࡢࡲࡲ⤒㐣ࡋࠊ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊᇶᗏ್ࢆ♧ࡋࠊ᤼༸ࡢ೵Ṇࡀ㉳ࡇࡗࡓࡀ

᭶௨㝆ࡣࠊ෌ࡧ࿘ᮇⓗኚ໬ࢆ♧ࡋࡓࠋ⾑୰ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘࡣࠊ⾑୰ࣉࣟࢪ

࢙ࢫࢸࣟࣥ⃰ᗘ࡜ྠᵝࡢኚ໬ࢆ♧ࡋࡓࠋ⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡣࠊ

ὶ⏘ᚋ

ᅇࡢୖ᪼ࡀㄆࡵࡽࢀࡓࡀࠊ ᭶࠿ࡽ ᭶ࡲ࡛ᇶᗏ್࡛⤒㐣ࡋࡓࠋ⾑୰࢖ࣥࣄࣅࣥ

⃰ᗘࡣࠊὶ⏘ᚋࡶࣆ࣮ࢡࣞ࣋ࣝ࡟ᕪࡣ࠶ࡿࡀࠊ ᭶ࡲ࡛࿘ᮇⓗኚ໬ࢆ♧ࡋࠊ

᭶࡜ ᭶ࡣࠊపୗࡋࡓࠋ

㸳㸫㸱㸫㸳㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜ࢸࢫࢺࢫࢸࣟࣥࡢศἪࣃࢱ࣮ࣥࡢẚ㍑

㸳㸫㸱㸫㸳㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜ࢸࢫࢺࢫࢸࣟࣥࡢศἪࣃࢱ࣮ࣥࡢẚ㍑)LJ)LJ)LJ)LJ

$%$%$%$%

㠀ዷፎ㤿

㸦࣐࢘ 1R㸧ࡢ ᖺ㛫ࡢ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘ ࡢኚ໬ࢆ )LJ$ ࡟ࠊዷፎ㤿㸦࣐࢘ 1R㸧ࡢ ᅇࡢዷፎᮇࡢ⾑୰ࣉࣟࢪ࢙ࢫ ࢸࣟࣥ࡜ࢸࢫࢺࢫࢸࣟࣥ⃰ᗘࡢኚ໬ࢆ )LJ% ࡟♧ࡋࡓࠋ㠀ዷፎᮇ࡛ࡶዷፎ ᮇ࡛ࡶࠊࣉࣟࢪ࢙ࢫࢸࣟࣥࡢୖ᪼࡜పୗࡢኚ໬࡜ࢸࢫࢺࢫࢸࣟࣥࡢୖ᪼࡜పୗ

ࡢኚ໬ࡣᖹ⾜ࡋࡓࠋ┦㛵ಀᩘࡣࡑࢀࡒࢀࠊU 3ࠊU 3࡛

࠶ࡗࡓࠋ

㸳㸫㸱㸫㸴㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝࡢศἪࣃࢱ࣮ࣥࡢẚ㍑

)LJ )LJ

)LJ)LJ

㠀ዷፎ㤿㸦࣐࢘ 1R㸧ࡢ ᖺ㛫ࡢ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜

ࣝ⃰ᗘࡢኚ໬ࢆ )LJ ࡟♧ࡋࡓࠋ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡀୖ᪼ࡋࡓ᫬

࡟ࠊ⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡣపୗࡍࡿኚ໬ࡀㄆࡵࡽࢀࡓࠋ┦㛵ಀᩘࡣࠊ U 3࡛࠶ࡗࡓࠋࡲࡓࠊ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝ

⃰ᗘࡀప್ࢆ♧ࡍ ᭶࠿ࡽ ᭶ࡲ࡛ࡣࠊ᤼༸ࡀ೵Ṇࡋࡓ࡜᥎ᐹࡉࢀࡓࠋ

㸳㸫㸱㸫㸵㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢖ࣥࣄࣅࣥࡢศἪࣃࢱ࣮ࣥࡢẚ㍑

㸳㸫㸱㸫㸵㸬ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢖ࣥࣄࣅࣥࡢศἪࣃࢱ࣮ࣥࡢẚ㍑)LJ)LJ)LJ)LJ

㠀ዷፎ㤿

㸦࣐࢘ 1R㸧ࡢ ᖺ㛫ࡢ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢖ࣥࣄࣅࣥ⃰ᗘࡢ ኚ໬ࢆ )LJ࡟♧ࡋࡓࠋ ᭶࠿ࡽ ᭶ࡢࣉࣟࢪ࢙ࢫࢸࣟࣥࡀ࿘ᮇⓗ࡞ኚ໬

ࢆ♧ࡋࡓ᫬ᮇ࡛ࡣࠊࣉࣟࢪ࢙ࢫࢸࣟࣥࡀୖ᪼ࡋࡓ᫬࡟ࠊ࢖ࣥࣄࣅࣥࡣపୗࡋࠊ

㏫࡟ࠊࣉࣟࢪ࢙ࢫࢸࣟࣥࡀపୗࡋࡓ᫬࡟ࠊ࢖ࣥࣄࣅࣥࡣୖ᪼ࡋࡓࠋ┦㛵ಀᩘࡣ

U 3࡛࠶ࡗࡓࠋ

ࣉࣟࢪ࢙ࢫࢸࣟࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝࡣࠊ㏫ࡢศἪࣃࢱ࣮ࣥࢆ♧ࡋࡓࠋ

㸳㸫㸱㸫㸶㸬࢖ࣥࣄࣅࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝࡢศἪࣃࢱ࣮ࣥࡢẚ㍑

㸳㸫㸱㸫㸶㸬࢖ࣥࣄࣅࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝࡢศἪࣃࢱ࣮ࣥࡢẚ㍑)LJ)LJ)LJ)LJ

㠀ዷፎ㤿

㸦࣐࢘ 1R㸧ࡢ ᖺ㛫ࡢ⾑୰࢖ࣥࣄࣅࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡢ ኚ໬ࢆ )LJ ࡟♧ࡋࡓࠋ⾑୰࢖ࣥࣄࣅࣥ࡜࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡢኚ໬ࡣࠊ

⾑୰࢚ࢫࢺࣛࢪ࣮࢜ࣝ⃰ᗘࡀୖ᪼ࡋࡓ᫬࡟ࠊ⾑୰࢖ࣥࣄࣅࣥ⃰ᗘࡶୖ᪼ࡋࠊ࢚

ࢫࢺࣛࢪ࣮࢜ࣝࡀపୗࡋࡓ᫬࡟ࠊ࢖ࣥࣄࣅࣥࡣపୗࡍࡿᖹ⾜㛵ಀࢆ♧ࡋࡓࠋ

࡞࠾ࠊ┦㛵ಀᩘࡣ U 3࡛࠶ࡗࡓ

㸳㸫㸲㸬⪃ᐹ 㸳㸫㸲㸬⪃ᐹ㸳㸫㸲㸬⪃ᐹ 㸳㸫㸲㸬⪃ᐹ

㸳㸫㸲㸫㸯㸬㞤ࢧࣛࣈࣞࢵࢻࡢ⏕Ṫᶵ⬟ࡢᖺ࿘ᮇ 㸳㸫㸲㸫㸯㸬㞤ࢧࣛࣈࣞࢵࢻࡢ⏕Ṫᶵ⬟ࡢᖺ࿘ᮇ 㸳㸫㸲㸫㸯㸬㞤ࢧࣛࣈࣞࢵࢻࡢ⏕Ṫᶵ⬟ࡢᖺ࿘ᮇ 㸳㸫㸲㸫㸯㸬㞤ࢧࣛࣈࣞࢵࢻࡢ⏕Ṫᶵ⬟ࡢᖺ࿘ᮇ

ᮏ◊✲࡛ࡣࠊ໭ᾏ㐨࡛㣫⫱ࡉࢀ࡚࠸ࡿ 㢌ࡢ㞤ࢧࣛࣈࣞࢵࢻ⦾Ṫ∷㤿࠿ࡽ⣙

ᖺ㛫࡟ࢃࡓࡗ࡚᥇⾑ࡋ࡚ࠊ ✀㢮ࡢ⏕Ṫ㛵㐃࣍ࣝࣔࣥࢆ ᐃࡍࡿࡇ࡜࡟ࡼࡾࠊ 㞤࣐࢘ࡢ ᖺ㛫ࡢどᗋୗ㒊࣭ୗᆶయ࣭༸ᕢᶵ⬟ࡢᖺ࿘ᮇⓗኚ໬ࢆ᫂ࡽ࠿࡟ࡍࡿ

࡜ඹ࡟ࠊ᏶඲⏕Ṫ࿘ᮇ࡟࠾ࡅࡿྛ✀࣍ࣝࣔࣥࡢศἪኚ໬ࢆ᫂ࡽ࠿࡟ࡋࡓࠋ

⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࡣࠊ᫂░࡞Ꮨ⠇ኚ໬ࢆ♧ࡋࡓࠋ༶ࡕࠊ᪥㛗᫬㛫ࡀ㛗࠸

Ꮨ⠇࡟ࡣ㧗ࡃࠊ᪥㛗᫬㛫ࡀ▷࠸Ꮨ⠇࡟ࡣప࠸್ࢆ♧ࡋࡓࠋ-RKQVRQ ࡽࡣࠊ ࢫࢱࣥࢲ࣮ࢻࣈࣞࢵࢻ✀ࡢ㞤࣐࢘ࢆ⏝࠸࡚⾑୰ࣉࣟࣛࢡࢳࣥ⃰ᗘࢆ ᐃࡋࠊᮏ

◊✲࡜㢮ఝࡋࡓᖺ࿘ᮇࡢ࠶ࡿࡇ࡜ࢆሗ࿌ࡋ࡚࠸ࡿࠋ

⾑୰ /+⃰ᗘࡣࠊ㛗᪥ᮇ࡟⧞ࡾ㏉ࡉࢀࡿ᤼༸࡟కࡗ࡚࿘ᮇⓗ࡞ୖ᪼࡜పୗࡀㄆ

ࡵࡽࢀࡓࠋࡲࡓࠊ▷᪥ᮇ࡟ࡣࠊ⾑୰ /+⃰ᗘࡣᇶᗏࣞ࣋ࣝࡢࡲࡲ⥔ᣢࡉࢀࠊ᤼༸

ࡀ೵Ṇࡍࡿ஦ᐇࡀ☜ㄆࡉࢀࡓࠋࡋ࠿ࡋࠊ▷᪥ᮇ࡟࠾ࡅࡿ⾑୰ /+⃰ᗘࡢపୗ࡜᤼

༸೵Ṇᮇ㛫ࡣࠊ࣐࢘ࡢಶయ࡟ࡼࡗ࡚㐪࠸ࡀ࠶ࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋ/+ ศἪ

࡟㛵ࡋ࡚ࡣࠊ༸⬊Ⓨ⫱࡟ࡼࡿ࢚ࢫࢺࣛࢪ࣮࢜ࣝࡢศἪୖ᪼࡟ࡼࡿṇࡢࣇ࢕࣮ࢻ

ࣂࢵࢡ࡟ࡼࡾࠊどᗋୗ㒊࠿ࡽ࢟ࢫ࣌ࣉࢳࣥࡢศἪࢆಁ㐍ࡋ࡚ࠊ*Q5+ ࡢศἪࢆಁ

㐍ࡋࠊ⤖ᯝ࡜ࡋ࡚ୗᆶయ࠿ࡽࡢ /+ ࡢࢧ࣮ࢪ≧ศἪࡀಁ㐍ࡉࢀ᤼༸ࢆಁࡍࡇ࡜ࡀ

▱ࡽࢀ࡚࠸ࡿ㸦=HHVKDQHWDO㸧ࠋ㞤࣐࡛࢘ࡣࠊ᤼༸ᚋࡶ⾑୰ /+⃰ᗘࡣࠊ

㹼 ᪥ࡣ㧗࠸್ࢆ⥔ᣢࡋࠊ㯤యᙧᡂ࡟ࡼࡾ⏘⏕ࡉࢀࡿࣉࣟࢪ࢙ࢫࢸࣟࣥ࡟ࡼࡾ

ᢚไࡉࢀ࡚పୗࡍࡿࠋ㞤࣐࢘ࡣࠊ௚ࡢ့ஙື≀࡜␗࡞ࡾࠊ/+ ࢧ࣮ࢪࡀ 㐌㛫⛬

ᗘ㛗ࡃᣢ⥆ࡍࡿࡓࡵࠊᮏ◊✲ࡢࡼ࠺࡞ 㐌㛫㝸࡛ࡢ᥇⾑࡛ࡶࠊୖ᪼࡜పୗࢆ☜

ㄆࡍࡿࡇ࡜ࡀྍ⬟࡛࠶ࡗࡓࠋ

⾑୰ )6+ ⃰ᗘࡶ㛗᪥ᮇ࡟ศἪࡀஹ㐍ࡍࡿഴྥࢆ♧ࡍࡇ࡜ࡀุ᫂ࡋࡓࠋ⾑୰ )6+

⃰ᗘࡣࠊⓎ᝟࿘ᮇ୰ࡣࠊ㯤యᮇ࡟ୖ᪼ࡋ࡚ࠊ㯤యᮇ୰࡟༸⬊ࢆⓎ⫱ࡉࡏࡿࠊᡤ

ㅝ༸⬊Ⓨ⫱Ἴࡢฟ⌧ࢆಁ㐍ࡍࡿࠋࡑࡢᚋࠊ༸⬊࠿ࡽศἪࡉࢀࡿ࢖ࣥࣄࣅࣥ࡟ࡼ

ࡾ )6+ ศἪࡀᢚไࡉࢀ࡚⾑୰ )6+ ⃰ᗘࡀపୗࡍࡿࡀࠊ࢖ࣥࣄࣅࣥ⏕⏘ࡢపୗ࡟

కࡗ࡚෌ࡧୖ᪼ࡋࠊୖ᪼࡜పୗࢆ⧞ࡾ㏉ࡍࠋ⾑୰ࣉࣟࢪ࢙ࢫࢸࣟࣥ⃰ᗘࡣࠊ᤼

༸ᚋ࡟㯤యࡢᙧᡂ࡜ඹ࡟ୖ᪼ࢆ♧ࡋࠊ㈇ࡢࣇ࢕࣮ࢻࣂࢵࢡ࡜ࡋ࡚ࠊ/+ ࡢศἪࢆ

ドキュメント内サラブレット種雌馬の生殖周期各ステージにおける内分泌調節機構に関する研究 (ページ 53-67)