[PDF] Top 20 株主通信 2015年3月期（2014年度） 第62期｜[財務情報] IR資料ライブラリー｜＜株主・投資家の皆さまへ＞ IR情報｜NIPRO－ニプロ株式会社－ 「その技術は、人のために。」
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Crucial Role of Extracellular Signal-regulated Kinase Pathway in Reactive Oxygen Species-mediated Endothelin-1 Gene Expression Induced by Endothelin-1 in Rat Cardiac Fibroblasts.
... Abstract Endothelin-1 (ET-1) has been implicated in fibroblast ...the role of endogenous ET-1 in ET-1–stimulated fibroblast proliferation and to investigate ... 完全なドキュメントを参照
1
Role of reactive oxygen species-sensitive extracellular signal-regulated kinase pathway in angiotensin II-induced endothelin-1 gene expression in vascular endothelial cells
... ET-1 gene was induced with Ang II, which was inhibited with Ang II type 1 receptor antagonist ...inhibited by irbesartan and several antioxidants, and antioxidants also suppressed Ang ... 完全なドキュメントを参照
2
Role of reactive oxygen species-sensitive extracellular signal-regulated kinase pathway in angiotensin II-induced endothelin-1 gene expression in vascular endothelial cells.
... ET-1 gene was induced with Ang II, which was inhibited with Ang II type 1 receptor antagonist ( ...inhibited by irbesartan and several antioxidants, and antioxidants also suppressed Ang ... 完全なドキュメントを参照
9
Uric acid activates extracellular signal-regulated kinases and thereafter endothelin-1 expression in rat cardiac fibroblasts.
... levels of uric acid may have a causal role in hypertension and cardiovascular ...effect of uric acid on cardiac cells remains ...effect of uric acid in rat ... 完全なドキュメントを参照
Inhibition of angiotensin II induced endothelin-1 gene expression by 17-beta-oestradiol in rat cardiac fibroblasts.
... II) induced cell proliferation and to identify the putative underlying signalling pathways in rat cardiac ...Cultured rat cardiac fibroblasts were preincubated with E2 ... 完全なドキュメントを参照
1
Inhibition of angiotensin II induced endothelin-1 gene expression by 17-beta-oestradiol in rat cardiac fibroblasts.
... The effect of E(2) on Ang II induced NADPH oxidase activity, reactive oxygen species (ROS) formation, and extracellular signal regulated kinase (ERK) phosphorylation were tested to elu[r] ... 完全なドキュメントを参照
1
17β-estradiol downregulates angiotensin-II-induced endothelin-1 gene expression in rat aortic smooth muscle cells
... ET-1 gene expression were examined. The effect of E2 on Ang-II-induced extracellular signal-regulated kinase (ERK) phosphorylation was tested to elucidate ... 完全なドキュメントを参照
Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells.
... endothelin-1 gene expression were examined. The intracellular mechanism of resveratrol in cellular proliferation and endothelin-1 gene expression was ... 完全なドキュメントを参照
2
Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells
... ET-1 gene expression and ERK ...ET-1 expression. Co-transfection of dominant negative mutant of Ras, Raf and MEK1 attenuated the Ang II-increased ET-1 ... 完全なドキュメントを参照
Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells
... II-induced extracellular signal-regulated kinase (ERK) phosphorylation were performed to elucidate the redox-sensitive pathway in proliferation and ET-1 gene ... 完全なドキュメントを参照
Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells.
... ET-1 gene expression was ...II-induced extracellular signal-regulated kinase (ERK) phosphorylation were performed to elucidate the redox-sensitive pathway ... 完全なドキュメントを参照
2
Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hyptertrophy
... The effects of antioxidant pretreatment on ET-1- mduced cardiac hypertrophy and mitogen-activated protein kinase (MAPKs) phosphorylation were studied to elucidate the redox- sensitive [r] ... 完全なドキュメントを参照
2
Reactive Oxygen Species Generation Is Involved in Epidermal Growth Factor Receptor Transactivation through The Transient Oxidization of SHP-2 in Endothelin-1 Signaling Pathway in Rat Cardiac Fibroblasts.
... Detection of the oxidization levels of PTP by using modified malachite green-PTP ...principle of modified malachite green-PTP ...harvested in lysis buffer containing ...ROS in ... 完全なドキュメントを参照
3
Reactive Oxygen Species Generation Is Involved in Epidermal Growth Factor Receptor Transactivation through The Transient Oxidization of SHP-2 in Endothelin-1 Signaling Pathway in Rat Cardiac Fibroblasts.
... Abstract Endothelin-1 (ET-1)is implicated in fibroblast proliferation ,which results in cardiac ...Both reactive oxygen species (ROS) generation and ... 完全なドキュメントを参照
7
The antioxidative effect of propofol on angiotensin II-induced cell proliferation and endothelin-1 gene expression in rat cardiac fibroblasts.
... effects of the pretreatment of cardiac fibroblasts with propofol for 30 min followed by exposure to Ang II for 24 h resulted in a significant decrease in Ang-II-increased ... 完全なドキュメントを参照
1
Nitric Oxide Inhibits Endothelin-1-Induced Cardiomyocyte Hypertrophy through cGMP-mediated Suppression of Extracellular-Signal Regulated Kinase Phosphorylation
... the role of these free radicals in the development of cardiac hypertrophy remains ...unclear. In this study, we investigate NO modulation of cellular signaling in ... 完全なドキュメントを参照
3
Tetramethylpyrazine downregulates angiotensin II-induced endothelin-1 gene expression in vascular endothelin cells
... ET-1 gene expression, as revealed by nothern blotting and a promoter activity ...increase in intracellular reactive oxygen species (ROS), as measured by the ... 完全なドキュメントを参照
9
Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts.
... important role in cardiac remodeling and fibrosis. Cardiac fibroblast is the cell type known to proliferate during cardiac fibrosis and to produce the excess matrix proteins ... 完全なドキュメントを参照
10
Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts.
... important role in cardiac remodeling and fibrosis. Cardiac fibroblast is the cell type known to proliferate during cardiac fibrosis and to produce the excess matrix proteins ... 完全なドキュメントを参照
1
Inhibition of cyclic strain-induced endothelin-1 gene expression by resveratrol
... found in grapes and is among the major constituents of wine thought to have a cardioprotective ...effect. Endothelin-1 (ET-1) is a potent vasopressor synthesized by endothelial ... 完全なドキュメントを参照
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