[PDF] Top 20 2013年12月期 決算短信 決算短信 など | 大塚商会
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Cantharidin-Induced Cytotoxicity and Cyclooxygenase 2 Expression in Human Bladder Carcinoma Cell Line
... At a high dose (more 12.5 microM), cantharidin could stimulate T 24 cells to deplete a large number of ATP and induce secondary necrosis. In addition, cantharidin also stimulated COX 2[r] ... 完全なドキュメントを参照
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Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line
... The cytotoxicity of cantharidin was not significantly enhanced when T 24 cells were treated for a longer ...proteins and pro-caspase 3, Bcl-2 were significantly inhibited after ... 完全なドキュメントを参照
2
Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line
... used in clinical therapy, but is always accompanied by ...on bladder are attributed to its active principle: cantharidin. In the present study, we explored how cantharidin induces ... 完全なドキュメントを参照
2
Cantharidin-Induced Cytotoxicity and Cyclooxygenase 2 Expression in Human Bladder Carcinoma Cell Line
... At a high dose (more 12.5 microM), cantharidin could stimulate T 24 cells to deplete a large number of ATP and induce secondary necrosis. In addition, cantharidin also stimulated COX 2[r] ... 完全なドキュメントを参照
1
Tumor-Associated Macrophage-Induced Invasion and Angiogenesis of Human Basal Cell Carcinoma Cells by Cyclooxygenase-2 Induction
... 6,7 and Shiou-Hwa Jee 1,7 Tumor-associated macrophages (TAMs) and cyclooxygenase-2 (COX-2) are associated with invasion, angio- genesis, and poor prognosis in many ... 完全なドキュメントを参照
2
Cyclooxygenase-2 Overexpression in Human Basal Cell Carcinoma Cell Line Increases Antiapoptosis, Angiogenesis, and Tumorigenesis
... 0 and antisense 5 0 -AAC TTC TCC ACA ACC CTC TGC AC-3 0 ; VEGF-A: sense 5 0 -AGC TAC TGC CAT CCA ATC GC-3 0 and antisense 5 0 -GGG CGA ATC CAA TTC CAA GAG-3 0 ; platelet-derived growth factor: sense 5 0 - ... 完全なドキュメントを参照
1
Expression of Protein Kinase C α and the MZF-1 and Elk-1 Transcription Factors in Human Bladder Transitional Cell Carcinoma Cells
... Elk-1 and MZF-1 in the various differentiated urinary bladder transitional cell carcinoma (TCC) cells: 5637, BFTC905, TSGH8301, HT1376 and HT1197 ...potential in the five ... 完全なドキュメントを参照
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Effects of Ginkgo biloba extract on cell proliferation and cytotoxicity in human hepatocellular carcinoma cells.
... RESULTS: The results showed that EGb 761 (50-1 000 mg/L) significantly suppressed cell proliferation and increased LDH release (P<0.05) in HepG2 and Hep3B cells compared with the c[r] ... 完全なドキュメントを参照
Cantharidin induces DNA damage and inhibits DNA repair-associated protein expressions in TSGH8301 human bladder cancer cell.
... damage and condensation in TSGH8301 cells. To confirm CTD induced DNA damage in TSGH8301 cells which were evaluated by Comet assay, cells were exposed to 0 and 7,5 μM of CTD for 6, 24 ... 完全なドキュメントを参照
7
Suppressions of Migration and Invasion by Cantharidin in TSGH-8301 Human Bladder Carcinoma Cells through the Inhibitions of Matrix Metalloproteinase-2/-9 Signaling
... that cantharidin exerts an inhibitory effect on several essential steps of cancer cell metastasis, including cell adhesion, invasion, and migration via regulating the activities of ... 完全なドキュメントを参照
Cytotoxicity effects of cantharidin on the growth of normal and carcinoma cells
... The findings of damaged mitochondria in the cantharidin treated Hep 3B cells in this study suggest that cantharidin can induce acute and lethal toxic effects on Hep 3B cells by inhibit[r] ... 完全なドキュメントを参照
3
Effects of recombinant lysostaphin on cytotoxicity and interleukin-8 level in normal human epidermal keratinocytes cell line
... generation and secretion of IL-8 may provide a useful biomarker for determining skin irritants (Luster et ...production, and the regulation of inflammatory mediators in the skin will be of value ... 完全なドキュメントを参照
1
The Role of Functional Polymorphisms of Cyclooxygenase 2 in Renal Cell Carcinoma
... tumor, and the cancer cells did not respond well to radiotherapy or chemotherapy, but partially to targeted ...lacking and in an urgently need (21-23). In the present study, the association of ... 完全なドキュメントを参照
Cyr61 increases matrix metalloproteinase-3 expression and cell motility in human oral squamous cell carcinoma cells
... cells in recent years has identified various molecular pathways that are altered in different ...molecules in these ...barriers and overcome certain rules. Several discrete steps are ... 完全なドキュメントを参照
2
Pemetrexed downregulates ERCC1 expression and enhances cytotoxicity effected by resveratrol in human nonsmall cell lung cancer cells
... suppression and inhibits apoptosis, while overexpression of MEK1, which is directly upstream of both ERK1 and ERK2, enhances apopto- sis induced by resveratrol (Nguyen et ...increased ... 完全なドキュメントを参照
2
YC-1-induced cyclooxygenase-2 expression is mediated by cGMP-dependent activations of Ras, Akt, and NF-kB in human pulmonary epithelial cell
... YC-1-induced Akt activation was also inhibited by ODQ, KT-5823, manumycin A, and wortmannin. YC-1 caused the formation of an NF-kappaB-specific DNA-protein complex and an increase in ... 完全なドキュメントを参照
3
Apoptosis induced by uterine 24p3 protein in endometrial carcinoma cell line
... functions and reaction pathways of lipocalins in mammalian system were ...endometrial carcinoma cell line (RL95-2) was an experimental target for achieving the in vitro ... 完全なドキュメントを参照
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Cyclooxygenase 2 expression in pterygium.
... ticipated in this ...males and 39 females, with an age range of 50-83 years and an average age of ...patients and superior conjunctiva of 18 patients without pterygium and pinguecula ... 完全なドキュメントを参照
1
Subamolide B Isolated from Medicinal Plant Cinnamomum subavenium Induces Cytotoxicity in Human Cutaneous Squamous Cell Carcinoma Cells through Mitochondrial and CHOP-Dependent Cell Death Pathways
... the expression of BCL-2 family proteins was ...dose- and time-dependent reduction in the level of prosurvival BCL-2, whereas it barely modulates the levels of prosurvival BCL-xL or the ... 完全なドキュメントを参照
AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma
... involved in the CCL3 signaling ...A and compound C, antagonize CCL3-mediated cancer migration and MMP-2 expression, suggesting that AMPK activation is an obligatory event in ... 完全なドキュメントを参照
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