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The Antiplatelet activity of ketamine is mediated through suppression of phosphoinositide breakdown and an increase in cyclic GMP.
... In this study, Escherichia coli LPS dose-dependently (100-500 μg/ ml) and time- dependently (10-60 min) inhibited platelet aggregation in human and rabbit platelets stimulated by agonis[r] ... 完全なドキュメントを参照
The Antiplatelet activity of ketamine is mediated through suppression of phosphoinositide breakdown and an increase in cyclic GMP.
... coli LPS may be involved in the activation of a nitric oxide/cyclic GMP pathway in platelets, resulting in inhibition of platelet aggregation. Therefore, LPS-mediated alteration of pla[r] ... 完全なドキュメントを参照
The antiplatelet activity of PMC, a potent a-tocopherol analogue, is mediated through inhibition of cyclooxygenase. Br.
... (collagen and ADP).PMC also dose-dependently inhibited the intracellular Ca2+ mobilization, whereas it did not inhibit phosphoinositide breakdown in human platelets stimulated by ...(10 ... 完全なドキュメントを参照
The antiplatelet activity of PMC, a potent a-tocopherol analogue, is mediated through inhibition of cyclooxygenase. Br.
... (collagen and ADP).PMC also dose-dependently inhibited the intracellular Ca2+ mobilization, whereas it did not inhibit phosphoinositide breakdown in human platelets stimulated by ...(10 ... 完全なドキュメントを参照
α-Naphthoflavone, a Potent Antiplatelet Flavonoid, Is Mediated through Inhibition of Phospholipase C Activity and Stimulation of Cyclic GMP Formation
... (1) α-NF may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown, protein kinase C activation, and thromboxane A2 formation, thereby leading[r] ... 完全なドキュメントを参照
4
alpha-Naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
... (1) alpha-NF may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown, protein kinase C activation, and thromboxane A(2) formation, thereby l[r] ... 完全なドキュメントを参照
2
Alpha-naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
... alpha-NF (5 and 10 microM) inhibited intracellular Ca(2+) mobilization, phosphoinositide breakdown, and thromboxane A(2) formation stimulated by collagen (1 microg/mL) in human platele[r] ... 完全なドキュメントを参照
Alpha-naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
... (1) alpha-NF may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown, protein kinase C activation, and thromboxane A(2) formation, thereby l[r] ... 完全なドキュメントを参照
The antiplatelet activity of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, is mediated through inhibition of phospholipase C.
... to the inhiother hand, rutaecarpine (50 and 100 mM) dose- bition of phospholipase C activity, leading to redependently inhibited the increase in intracellular duce ... 完全なドキュメントを参照
Mechanisms of antiplatelet and antithrombotic activity of midazolam in invitro and in vivo studies
... Midazolam is widely used as a sedative and anesthetic induction agent. The aim of this study was to systematically examine the inhibitory mechanisms of midazolam in ... 完全なドキュメントを参照
1
Mechanisms of antiplatelet and antithrombotic activity of midazolam in in vitro and in vivo studies
... Midazolam is widely used as a sedative and anesthetic induction agent. The aim of this study was to systematically examine the inhibitory mechanisms of midazolam in ... 完全なドキュメントを参照
1
The antiplatelet activity of Escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway.
... In this study, Escherichia coli LPS dose-dependently (100-500 μg/ ml) and time- dependently (10-60 min) inhibited platelet aggregation in human and rabbit platelets stimulated by agonis[r] ... 完全なドキュメントを参照
The antiplatelet activity of escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway.
... microg/ml) and time-dependently (10-60 min) inhibited platelet aggregation in human and rabbit platelets stimulated by ...inhibited the intracellular Ca2+ mobilization in human ... 完全なドキュメントを参照
2
Antiplatelet activity of caffeic acid phenethyl ester is mediated through a cyclic GMP-dependent pathway in human platelets.
... The present study reports a novel and potent antiplatelet agent, CAPE, which involved in the following inhibitory pathways: CAPE increases cyclic GMP/VASP Ser157 phosphorylation, and s[r] ... 完全なドキュメントを参照
3
Antiplatelet activity of Staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway
... In this study, Gram-positive Staphylococcus aureus lipoteichoic acid (LTA) dose dependently (0.1-1.0 microg/mL) and time dependently (10-60 min) inhibited platelet aggregation in human[r] ... 完全なドキュメントを参照
2
Antiplatelet activity of staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway
... CH and Lin CH Abstract In this study, Gram-positive Staphylococcus aureus ence ...mg/mL) and time dependently (10–60 min) inhib- Key Words: Gram-positive bacteria; LTA; Platelet aggreited platelet ... 完全なドキュメントを参照
Antiplatelet activity of staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway
... CH and Lin CH Abstract In this study, Gram-positive Staphylococcus aureus ence ...mg/mL) and time dependently (10–60 min) inhib- Key Words: Gram-positive bacteria; LTA; Platelet aggreited platelet ... 完全なドキュメントを参照
Antiplatelet Activity of Staphylococcus aureus Lipoteichoic Acid Is Mediated Through a Cyclic AMP Pathway
... In this study, Gram-positive Staphylococcus aureus lipoteichoic acid (LTA) dose dependently (0.1-1.0 microg/mL) and time dependently (10-60 min) inhibited platelet aggregation in human[r] ... 完全なドキュメントを参照
9
The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.
... Furthermore, TMPZ concentration (50 and 200m M)- and time (15 and 30 min)-dependently triggered endothelial- type constitutive nitric oxide synthase (ecNOS) protein expr[r] ... 完全なドキュメントを参照
The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.
... Furthermore, TMPZ concentration (50 and 200m M)- and time (15 and 30 min)-dependently triggered endothelial- type constitutive nitric oxide synthase (ecNOS) protein expression in huma[r] ... 完全なドキュメントを参照
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