• 検索結果がありません。

神経症傾向,外向性と連続刺激への聴覚誘発電位

N/A
N/A
Protected

Academic year: 2021

シェア "神経症傾向,外向性と連続刺激への聴覚誘発電位"

Copied!
8
0
0

読み込み中.... (全文を見る)

全文

(1)Title. 神経症傾向,外向性と連続刺激への聴覚誘発電位. Author(s). 田中, 豪一; 新岡, 正; 萩野, 悦子; 津村, 直子; 荒島, 真一郎. Citation. 北海道教育大学紀要. 第二部. C, 家庭・養護・体育編, 48(1): 43-49. Issue Date. 1997-08. URL. http://s-ir.sap.hokkyodai.ac.jp/dspace/handle/123456789/2015. Rights. Hokkaido University of Education.

(2) . 平成9年8月 Au主犯s t ,1997. 北海道教育大学紀要 (第2部C) 第4 8巻 第1号 i ion (Sec ion nc)VO . I ty ofEducat t JournalofHokkaido Univers ‐48 . , NO. Neurot icisnl Extraversion and the Audi tory Evoked ,. Potent ial s to. a. st i lnulus Train. Gohichi TANAKA Tadashi NI IOKA* Etsuko HAGIN0 Na oko TSUMURA, , , , r ichi 1頭A and Shin- rO ARAS日1 Depan I Hea l l l iver ヒ r nentofSchoo th i i ty ofEducat ege s on Sapporo ,Sapporo Co , Hokkaido Un , Sappor。001 *Depar i i ine G d IEardhSc i tロ Schoo lofEnv i ido Uni i taIM【 t ty l entofEnず ron qmen ron ed c r a 1 menta e a u ence s ver , , Hokka , Sapporo060. 神経症傾向, 外向性と連続刺激への聴覚誘発電位 田中 豪-・新岡. 正*・萩野 悦子・津村 直子・荒島真一郎 北海道教育大学札幌校養護教育学科. Abstract. Audi iaI tory evoked potent i 9 23 Sto a st 工 エ ーulus bain wererecordedin28femalesdldents ‐ ,aged l years‐. The st imulus train was cons isted of 3 repet S S3 wi i ive tones (S1 imulus t th l s interst , 2 ,. inte lat ively long intertrain inte th a re ) wi lat ionships between short lval term changes of s lval ‐ ‐ Re icism were determined‐ responses, extraversion and neurot. High‐neurot ici sm subjects showed more. ion ofN 「 1latency f ic i leint reduct rom S1tO S2 ロ]anlow‐neurot sm ones rovertsshowedsho貴er P2 , whi 1atencyto slandS2 せlanextraverts tsindicatethatthefunct ionsinvolvedintheshort term ‐ . Theresul latency changes of audi tory evoked potent ial iated wiロ ]せl s were assoc e biologicalbasis underlying ic i i neurot ty trai t s ln and extraversion as a personal ‐. lntroduct ion. Cons iderableevidencessuggestthatcerebralevoked potent ial )are 値ecentralcorrelates s(EPS ofpsychopathologicalstates(1 ‐ ,2). Wim regardtotheanxiety EP1atecomponent s havebeenfound ,. l ierin associat ion wi to occur ear th 値epathologicalanxietyinpsychoneuros i 3) iveef fectsof s( ‐ Sedat ianxiety dnlgs has show「n to reduce 値e ampl i ant tudes and to len淳hen 値e latenc ies of EP 1ate ) i lat components(4 tytrai ingtotheanxiety havebeeninvest tsre igated ‐ ontheotherhand,personal ,5 in normals us ing e lectroencephalography (EEG) and EP ,. measures ‐. Wi th regard tO Eysenck’ s. ici extraversion and neurot 6 sm ( ) inconsistent results have been often found in the literature (7‐11)‐. ,. one poss ible reason forsuch t he discrepanc・es mightbe the experimental paradigm, whichinteract. t h trait variables‐ VVe now wi. ions between i report h gh conrelat. (4 3). EP measures and personal i ty. vari ‐.

(3) . 44. in i i Goh iNI IOKA,Et i iTANAKA,Tadash ‐ rO ARASH1qA ch suko HAGIN0, Naoko TSUMURA,andSh ch. i iologicalbas i ty mediated the short‐term tsindicate thatthe phys s ofthe personal ables ‐ Theresul i thin a st lnulust rain. , changesofEPs Wi. M[ ethod. Twenty‐eightadul 9and23 years Wereselectedfrom a tfemalevolunteersbetweentheagesofl ic i i i ion(E) and neurot N)score sm( rextravers s ofthe sampleof82 undergraduatestudents on 山e bas ’scores Were scattered Widel on the two ley Personal i ty lnventory, so that subjects on the Mauds y lethe mean N score Was20 7 5(SD 12‐ 9( i ions SD ) ty dimens personal . . The mean E score Was 28 ‐ , Whi 28 1 lat ion between the E and N scores( icant Pearson7s corre ) 12 0 r=‐0 ) ;p>0 ‐ . ‐ ‐ , with no signif lt ime oflo i ion, wi imul i werelkHztone burst The audi th a r tory st seandfal s of9o ms durat i f lythrough earphones(Grason‐Stadler TDH 49P) mountedinc rcumaural muf s mspresentedbinaural , ’ i imulus ly measured Eachsubject ty ofst sthresholdforlkHz puretone wasprevious . Thentheintens iedin a sensation level i t l was determinedtot atthreshold and specif . ,60 dBSL ing a ial Short ) were exaIPined by present tory evoked potent term changes of audi s (AEPs ‐ ly long interval imul i Wi ive i ive train of st th relat t s between trains and then averaging AEPs repet i h h i i ionin a train‐ Thetrain cons i t sted ofthreetones rordinalpos accordingtothe ,andt eeac ser es. f4s(Fi th anintert rainintervalo ofthreetones was presented at a rate of one tone persecond g ‐ , wi 1 ) ‐ Af tached,the earphones were placed and a subject Wasseatedin a terthe electrodes were at losehereyes ingfor3 minutes ldedroom. Af terrest ructedtoc sound-proofedshie , , 値esubject Wasinst tendtot heseries ofthe tones‐ to avoid head and eyelr ーove]nents, andto at lobe using Ag/AgC1electrode EEG wasrecordedfrom Czlead referencedto a lef tear ‐ - lnter. 2ndS S2 imu lus ( } t imu l ( S3 ) 3r ds t ts ls imu l ( SI ) t us us. f Thesequenceo imulustone t s 4sec. n. n. r I. H . 日 . 日. lsec. l sec. sub tY j ec .T .. N1. SI. S2 S3. Fig‐ I. /. \ 政権 函dBSLt t s ,,nebur ,. 0. 1 0 0. 0 20. 3 00. 4 } 0 0 (mse c. lresponse Temporal structure o fthe s imulus train andtypi t ca i ivetones‐ t eerepet Waveformsto t加ビ. (44).

(4) . . i i i i i d せl to lmlus Tra n al stoa st l i i Neurot r raver s ona l l e Aud c s l n,Ext l y Evoked Potent. lect rodeimpedance was maintainedbelow 5 kQ e. 45. hon Koden EEG5109 The EEG wasamp l i f i ) ed(Ni. i l hi h tf tered atloo 日z( 3dB i l th af ter whichband-passedo5‐1000 日z(3dB dovm) wi ,thenfurther g -cut ion‐ The EEG data weresamP1ed at a rate of lof幻 before A/D convers down pointin 6 dB/octaverol. 500 points. ime 2 ms ing t ) for 512 sampl per s (. imulus l oo ms and ms epoch containing the pre‐st. f l ineaverages Werecomputed across l di k of i f imulus41 2 ms … - st post ,thenstored ona magnetc oppy s . lthesecond( irstst imul iinthetrain(SI S2 l 山ef ) imulus-by‐ imulus bytaking al ) 120trainsst st ,al ,and l ly f i AEps were digi tered by non‐phase tal i f icat ions ofcomponents lthet h i ) al rd(S3 ‐ Beforeident , t l f i t ormsby f ter :2o Hzlow pass for N1 component shi ,6 Hzlow pass for P2 componen ‐. Resul ts. i f icant i ies 甘l rough S1 to S3‐ There Were s Fig‐2 shows 廿l e changes in N1 and P2 1atenc g n n i ions tudes of Nl and P2 t ionsin N1 and P21atency underS2andS3condi reduct . Furthermore ,ampl le lchangesinlatenciesand ampl i ions ly reduced under S2 and S3condi t igni f icant ‐ Weres . Theparal tudesf rom S1to S2 werefoundto bethe abrupt ones. i iables and U EP ion coef f ic ients between t ty var Table l shows Pearson’s conr he personal elat. 1 9 5. 節. 1 ◎. 園. E 男. ^冨≧ } お忘亙. 1~. き. こ. 燈. 2. 1 8 5. 書. 9 0. 1 8 0. t imulus ts l s. t imulus 2nd s. imulus t 3r ds. i i t imulus Cond St ons. Fig .2. Changesin mean latencies and the i rstandard eronrs ▽dth F l h i l i i l l d i d i t t s lnuuscon ons e crcess owsthe N1latenciesand ‐ P i t コ t l 21 t squeres e aences ‐. (4 5).

(5) 46. G o h i c h i T A N A K A , T a d a s h i N I I O K A , E t s u k o H A G I N 0 N a o k o T S U M U R A a n d s h i n ‐i c h i r O A R A S H I I 虹 A , ,. T a bl e・ I. C o n re l a ti o n s b e t w e e n t h e P e r s o n a li t y v a r i a b l e s a n d 化 } e A E P. 1 a t e n c i e s i n 2 8 s u bj e c ts ‐. STIM ULUS CONDI TIONS VARIABLES. ls t. E ‐ SC O R E v s.. NI. LATENCY. N-SCORE. NI. LATENCY. vs.. ‐. u n d er. 0 .. 3. 3. 0 .. 0. 4. E ‐ SC OR E v s.. P2. LATEN CY. 0 .. 5. 1 **. P2. LATENCY. 0 .. 1. 5. vs.. each. s ti m Lu l u s. c o n d iti o n s‐. 2nd. * p < 0. 0 5 ,. T h ere. STIM ULUS. 0 .. 2. ‐. 0 .. 6 9 ***. 0 .. 4. 一. 0 .. 2. !. N‐SCORE. lp < 0. 1 0,. m easures. STIMULUS. 3r d. 8. * * p < 0. 0 1 ,. STIMULUS. 0 .. 1. 0. 0 .. 0. 2. 1 *. 0 .. 2. 1. 6. 0 .. 2. 9. ー. * * * p < 0. o o i,. s i g n i fi c a n t. N:28. c o r r e l a ti o n s. b et w e e n. e x t r a v e r s i o n a n d P 2 1 a t e n c i e s u n d e r S 1 (r = 0 ‐ 5 1 p < 0 . 0 1 ) a n d S 2 ( r = 0 4 1 p < 0 0 5 ) c o n d i ti o n s . , . . ,. T h a t is ,. w ere. P 2 1 a t e n c y f o u n d t o b e s h o rt e r i n in tr o v e rts t h a n n e g a ti v e c o r r e l a t i o n b e t w e e n n e u r o t i c i s m. p o s iti v e. l n a d d i ti o n t h e r e ,. e x t r a v e r t s‐. o n. 化 le o t h e r h a n d , せ l e r e w e r e. a. s i g r 立 fi c a n t. a n d N I 1 a t e n c y u n d e r S 2 c o n d i t i o n ( r = - 0 . 6 9 , p < 0 ‐ 0 0 1 )‐. o 値 e r w o r d s , H i g h - n e u r o t i c i s m s u b j e c t s s h o w e d t h e e a r li e r N 1 i n r e s p o n s e t o S 2 o n e s‐. w as. n o s i g n i fi c a n t c o r r e l a t i o n s. ln. 山 a n l o w ‐ n e u r o ti c i s m. b e t w e e n a m p li t u d e v a l u e s a n d d i e. p e r s o n a li t y v a r i a b l e s ‐ T h e m u l ti p l e r e g r e s s i o n a n a l y s e s w e r e a d a p t e d f o r f u r t h e r a n a l y s e s t o c o m b i n e d r e s p o n s e s t o s l a n d S 2, s i n c e r e s p o n s e s w e r e c h a n g e d a b r u p tl y fr o m w ere o bserve d v a ri a b l e s i n a. u n d e r S 3 c o n d i ti o n .. T he. S 1 t o S 2 a s m e n ti o n e d a b o v e a n d n o c o r r e l a ti o n s , th e s l a n d. resp o ns es to. s2. w er e e nter e d. a s in d e p e n d e nt. m u l ti p l e r e g r e s s i o n a n a l y s e s w i d i p e r s o n a li t y v a r i a b l e s a s d e p e n d e n t v a r i a b l e s ‐. F i g ‐ 3 s h o w s t h e r e l a ti o n b e t w e e n e s t i l n a t e d e x t r a v e r s i o n a n d t h e o b s e r v e d e x t r a v e r s i o n ‐ e s til n a t e d e x t r a v e r s i o n. w a s c a l c u l a t e d a c c o r d i n g d i e f o ll o w i n g 1 pー u l t i p l e r e g r e s s i o n e q u a t i o n ;. 50. -. ﹇ こ0 4 0. o . - …. の. し ① >. 丁. 閏. L. .. .. ・ ・. 州 3 0 × 国 ℃ ① 〉 r L の め. ・. .. ・・. U. ”. 山. ・. . . ・.. 20. ぬ ^. ・. ・. .. 10. 0. 1 0. 20. 3 0. 4 0. 5 0. ^. E : E s ti m a te d E x t r a v e r s i o n F i g. 3. R e l a ti o n s h i p b e t w e e n t h e e s t i m a t e d e x t r a v e r - sl o n a n d t h e o b s e r v e d e x t r a v e r si o n .. ( 46 ). T h e.

(6) . . in imul r i ionandt l i t i i to New「 al stoa st e コ l us Tra e Aud r raver s ot c sm,Ext l y Evoked Pot. ド ー ーのー U一 ー ①ー r Lo切口^ 7 ー ℃①> ー Z - 仁 UL-ゴ n Y”. ◎ 。. 47. ◎ ◎. ◎ ◎ ◎. ◎ ◎◎. ◎. ◎ . ◎. ◎ ◎. ◎ ◎◎. 0. ◎. 10. 20. 30. 40. 50. ^. imated Neuroticism N:Est. Fig .4. Relat ionship. between the est imated. nel lr-. i i ot c sm andthe obsel・red new「oticism‐. E=o 45×1+0 10 55X2‐158 ‐ ‐ ‐ f iple correlation coef icient R=0 t ) (mul ‐71 ,n=28 : P21atency to S2 where XI :P21atency to sl ; X2 ‐ Thi ion accountedfor50% variance in 伍e observed extravers ion. Thati sre s ≦ p ress ,in官overt ion of P2latency he extravert showed shorter P21atency to sl and s2 せlan d ‐ Therefore , せlereduct ike ly to beindePendent of せl 官○ ]m S1to S2 wasl e extraversion. Fig‐4 shows 口 i ic i t i ici lnated neurot ln and 口le observed neurot s snl e relation between est ‐ The i ic i lowing 窟ー iP1eregress ion equat ion; t est lnated neurot s ln was calculated according 七hefol ul. N=0 61X2十119 36 .51XI-0 ‐ ‐ ion coef iple correlat f icient R=0 t (mul ‐74 ,n=28) where XI : NI1atency to sl : NI1atency to S2 ; X2 . Thi ionaccountedfor55 % var ianceintheobsewed neurot ic i t wassuggested 仕l sregress sm‐ l at high‐neurot ic i ion of NI1atency f ici sm showed morereduct rom S1to S2 値anlow‐neurot sm.. Discusslon. The present exper imentshowedthe clear re lat ionships between neuroticism, extraversion and i AEP1atenciesinthest ter l iest i ・nulustrain paradignl ‐ ln changesofEPsinresponsestot ・nulus ‐ Short ic and consi train have beenreported,in wh i t コ h in a train have been found stentChanges wi ch systemat i ion ( 12‐14 th the latency of some late components accompanied by ampl tude reduct ) wi ‐ Several di f ferent funct ion could be involved in 廿l ese changes ‐ The N1 component in panicular occurred. (47).

(7) . 48. i iTANAKA,Tadash Goh iN工 1OKA,Et in i i ASHI I 頭A ch suko HAGIN0,Naoko TSUMURA,andsh ‐ ch ro AR ‐. ly ear l ive ier wi imul iby hab th repeated st ion has been supposed to i i 12 tuat ) progress on( ‐ Habituat ion ic i th extravers associate wi tcouldbeexpectedthattheshort term sm and anxiety(15) ‐ ‐ Soi ,neurot ial ionships between EPsand persona1 here1at i iab1es ty var s mediatedt changesofevoked potent . on ing a condi the other hand,introduc ioning st imulusl s before onset of an evoking st imulus brought t ionofN1and P21atencies 値anhabi ion( 16) tuat t about moreabruptreduct sshowed ‐ Thepresentresul ion in latenc ies of N1 and P2 so thati abrupt reduct t can not be due to the progressive change in habi ion‐ tuat lndividualdi f ferences along the neurot ic ism dimension have been accounted forbyindividual di f ferencesintheemot l ionallabi i ivat ion ofautonomicfunct ions( 6 ty,i ) ‐e ‐ ‐ However ,act ,thepsycho- iologicalresearch ofneurot icism,in whichautono iables were measured,havenotfoundthe ]micvar phys iologicalcorrelates ofneurot i ionthat日 ici t i imbicst t sm‐ Now,thepropos el ructuresshouldbethe phys biologicalbas i ion and neurot ici ic i ) sofextravers sm (17 rescentral measureofneurot sm instead ,requi. he autononlic responses ion in the ts demonstratedthatthe NIlatency reduct oft ‐ The presentresul imulustrain could be a proml ici st s・ng measure ofthe neurot sm. Thefactthatthe NIlatencyto S2 コ t ieneurot ic i ientchange wi imulustrainis thinthest andt sm were highly correlatedsuggeststhattrans ion ofcentral nervous system re involvedint ic levantto the neurot hefunct i sm‐ l f ferences along the extravers t has been proposed that individual di ion dimension may be f ferencesin ロコecort ical arousal ico- icularloop which modulatescort accounted f orbyindividualdi ret. i bi ion( 6 t ) andi nh ‐ lfshorter P21atencyinintrovertcan be explained byincreasedlevels ofconical lectrophys ivi iological measureofcort icalarousaL ty,P21atency maybea directe act. Andtherelat ion. betweenextravers ion and P21atencyisthoughtto be mediatedbythedi f ferentunder lying mechani sm f ici ion wasfound under S1 and s2condi ions hi t rom thatin neurot sm,becauset srelat . Somere lat ionships have beensuggestedbetween anxious stateand EPs and dielat ter may be , ing the anxious state of pat ient for the cl inical purpose‐ a promls.ng l r l etnod for evaluat. Present. l inical and pharmachological f indings to normal personal i ts extended c ial ty t ts resul rai ‐ Potent ludes explor ing the re lat ionship between anxious state and basic personal i ty trai t research i nc , and led analys i ion processing in neurot icindividual more detai s oftheinformat s ‐. References iologi i l 1) C ) calcorrelatesof mentald sorders(Kager . ‐Shagassetal ‐ . , Neurophys , Base ,1984. 2) C‐Shagas l l i 1978 ) seta o at . .Psych .13 ‐ ,Bi ,163( ine 3) A.J 1974 ) caI Medic -4 ‐Bond,D.C ‐Jamesand M. H.Lader . ,Psychologi ,364(. 4) A.L i i 1974 ) sand M. H. Lader,PsychologicaI Med ne c -Bond,D.C .Jame ‐ .4 ,374( H f K b l i k i d S i l; l t t t f C 1 i i I Pharmacology, Therapy and 5) V‐ M. He]丁ma.pn, ▽『 o ma n n a n n r n a o n o u c e a uma o n ca . . ,. 6). l 1981 toxi ) co ogy .19 . ,56( 日.J E k B l i i i i l i i l d n ty(Thomas s e c o o c ) s sofper sona ngf e y g alba ‐ ・ , ,Spr ,i967. 7) R‐D.Savage ia 1964 t ) .Psych ‐110 ‐1 . ,Br ,98( 丑 l l l 8) A. G1assand A.Broa( i i 1966 t t ) roenceph ur s ec n ophys o ‐c .Newr .21 ‐ ,E1 ,309( l 1969 9) A.Gale, M.ColesandJ ) aydon ‐B1 ‐j .Psycho .60 . ,Br ,209( P 10 )J R d Y M H L d G ▽ F B P h i 1971 t ) on g ‐ . ‐ ow・ .J ‐ syc a .119 . , . . a eran . . ent , r ,667( )J 11 R h l P h l i 8 9 1 2 2 0( 1 9 7 5 t J ) m u s c o s o s c o p p y y ‐ . . . , ‐ ,‐ ) R. Naatanen and T・Picton,Psychophysiology,24,375(1987) 12 .. (48).

(8) . 1 in i 1 imu i i i i Neurot tory Evoked Pot us Tra ent a stoa st raver S onandthe Aud c sm,Ext . 2(Karger ) 13 ) A.obman and M.Lader,Pro鱒ressin clmicalneurophysiology ‐ . ,1977 , Base ,vol 1979 iol ) la and T‐J. Teyler 14 ) A.L‐ Mege . .Psychol ‐93 .comp.Phys ,1154( ,J ’Gorman Biol P h l 2 5 7( 1 9 7 7 5 ) 15 )1 ○ G s c o - ., ‐ y , . - iol 1973 Neurophys E 1 h l i ) l t 16 ) R. A‐But n er e c r o e n c e c p . ‐35 . . ,337( , i iate analys ivar 17 )J caltheory sand psychologi . .(Academic Press , London,1973) ‐A‐Gray, Mult. (49). 49.

(9)

参照

関連したドキュメント

単発持続型直列飛石型 ︒今 対缶不l視知覚

|﹁ひとつむすびてはゆひ︐I︑して﹂

⑫ 亜急性硬化性全脳炎、⑬ ライソゾーム病、⑭ 副腎白質ジストロフィー、⑮ 脊髄 性筋萎縮症、⑯ 球脊髄性筋萎縮症、⑰

要旨 F

引火性液体 : 区分4 眼に対する重篤な損傷性/ : 区分2B 眼刺激性 警告 眼刺激 可燃性液体

安全性は日々 向上すべきもの との認識不足 安全性は日々 向上すべきもの との認識不足 安全性は日々 向上すべきもの との認識不足 他社の運転.

安全性は日々 向上すべきもの との認識不足 安全性は日々 向上すべきもの との認識不足 安全性は日々 向上すべきもの との認識不足 他社の運転.

必修 幼二種 単位 ディプロマポリシーとの関連性