全文
数理生物学演習
第６回 ランダムな現象：
遺伝的浮動，ライト-フィッシャーモデル
1
野下 浩司（Noshita, Koji）
!
理学研究院 数理生物学研究室
発展
2
Kimura & Ohta, 1969, Genetics
突然変異固定までの平均待ち時間
再現したい図
（ただし課題では集団サイズが異なる）
• Kimura, M., Ohta, T. (1969). The Average Number of Generations until Fixation of a Mutant Gene in a Finite Population. Genetics 61(3), 763-71. https://www.ncbi.nlm.nih.gov/pubmed/17248440
それぞれの曲線は
に基づく．
T(p) = − 1
p {2N(1 − p)loge(1 − p)}
各点は の初期値に応じて
計算された待ち時間 の平均値 p
T
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