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Multidisciplinary Translational Research Lab, Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan

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486 2020122 6

122 6 PCN 2020 6 1 486

Toward the establishment of neurophysiological indi- cators for neuropsychiatric disorders using transcra- nial magnetic stimulationevoked potentialsA sys- tematic review

Y. Noda

Multidisciplinary Translational Research Lab, Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan

TMS

TMS

TMS EEG TMSEEG

TMS

TMSEEG

2018 9

PubMed TMS ORtranscranial magnetic

stimulation ANDEEG OR electroencephalog NOTrTMS OR repetitive transcranial magnetic stimulationOR TBS ORtheta burst stimulation

ANDhealthy TMSEEG

TMSEEG

TMSEEG TMSEEG

Polygenic risk scores in schizophrenia with clinically significant copy number variants

S. Taniguchi , K. Ninomiya, I. Kushima, T. Saito, A. Shimasaki, T. Sakusabe, Y. Momozawa, M. Kubo, Y. Kamatani, N. Ozaki, M. Ikeda and N. Iwata

Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan

SCZ

PRS

CNV500 kb

CNV10 kb

SCZ PRS CNV

CGH SNP SCZ 724 1,178 PRS

CNV

CNV

SCZ PRS

American College of

Medical Genetics CNV

CNV

CNV SCZ 66

CNV SCZ 658

CNV

CNV PRS PRS

CNV

PRS 10 CNV

22q11.2 47,XXY 47,XXX SCZ

CNV PRS

CNV SCZ PRS

(3)
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(5)
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490 2020122 6

122 6 PCN 2020 6 1 490

PFC GABA Glu PRESS

pointresolved spectroscopy

jMRUI

1

HMRS

POA PFC GABA

GABA Glu

GABA BIS11

MoCA

Glu BIS11

MoCA

PFC GABA

Glu

1

HMRS in vivo

POA

Figure 1 Clusters showing differences in the local gyrification index LGI among the diagnostic groups.

Cortical statistical maps displaying an increased LGI ina schizophreniaSz patients compared with healthy controlsHC , bschizotypal disorderSzTypalpatients compared with HC, and

cSz patients compared with SzTypal patients. The maps are shown for the right and left hemi - spheres in lateral and medial views, respectively. The horizontal bars show Pvalues corrected for multiple comparisons.

p.73

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図

Figure 1 Clusters showing differences in the local gyrification index LGI among the diagnostic groups

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