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分子神経生物学研究室 Molecular Neurobiology

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分子神経生物学研究室

Molecular Neurobiology

准教授    田渕 明子    Akiko Tabuchi 助 教    伊原 大輔    Daisuke Ihara

◆ 原 著

1) Kikuchi K*, Ihara D, Fukuchi M, Tanabe H, Ishibashi Y, Tsujii J, Tsuda M, Kaneda M, Sakagami H, Okuno H, Bito H, Yamazaki Y, Ishikawa M, Tabuchi A. Involvement of SRF coactivator MKL2 in BDNF-mediated activation of the synaptic activity-responsive element in the Arc gene. J Neurochem. 2019 Jan; 148(2): 204-18. doi: 10.1111/jnc.14596.

2) Fukuchi M, Okuno Y, Nakayama H, Nakano A, Mori H, Mitazaki S, Nakano Y, Toume K, Jo M, Takasaki I, Watanabe K, Shibahara N, Komatsu K, Tabuchi A, Tsuda M. Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice. Sci Rep. 2019 Aug ; 9(1): 11833. doi: 10.1038/s41598-019- 48361-4.

◆ 学会報告

1) Daisuke Ihara, Hiroki Tanabe, Shinnosuke Kato, Shiori Imanishi, Aya Kosaka Hiroyuki Sakagami, Akiko Tabuchi. SRF 写コアクチベーターMRTFBの神経活動依存的核移行制御.Neuro2019; 2019 Jul 25-28; 新潟.(ポスター) 2) 伊原大輔,田邉広樹,今西詩織,小坂彩,佐野友香里,阪上洋行,加藤真之佑,田渕明子.シナプスに存

在する転写活性化因子MRTFBの神経活動依存的な核移行と遺伝子発現制御機構に関する解析.日本薬学会北陸 支部第131回例会;2019 Nov 17;金沢.

3) Daisuke Ihara, Yuya Yamazaki, Natsumi Satou, Mamoru Fukuchi, Masaaki Tsuda, Akiko Tabuchi. Functional analysis of gene mutation of SRF coactivator MRTFB which was found in a patient with autism spectrum disorders. Toyama Forum for Academic Summit on "Dynamic Brain"; 2019 Dec 16-17;富山.(ポスター)

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