ナス科植物が産生する抗菌物質を輸送するトランスポーターを発見－ 農作物の病害防除技術への応用に期待 －

2

: ^-

8

Nb-ABCG1/2 19

27.5 ^-

9 - 2

- 1

2 - -

2

2 9

9 2

Nb- ABCG1/2

A

- 2 9

A -

2 1 2

28 4 22 The

Plant Cell ⁹

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EA

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R')S

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R')EMP@I Q BQ S

IPP MVA

pathway

DMAPP FPP 1. ^%6&

2. '"61

3. 76

6

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OH

HO

2

- 2

2 _Nb-

ABCG1/2

2 2 1 A

2 1 2 9

: Phytophthora infestans

4 1

1 1 19

2

A _/

800 ^{- 2 2}

-

27.5 US ⁹

-

- 1

2

- 1

Nicotiana benthamiana ^-

A

3,000

A ₈₂ 2

2

2 9 _{, 3}

A

 A2-189

2 A -

A 9

FPP 2 ^{1 9} 2 ^{A 9}

2 2 9 ₃

9

Nb-ABCG1/2 Nb-ABCG1/2 ²

3 ⁹

A - 2 1 A

5-epi-Aristolochene ^Farnesyl pyrophosphate (FPP)

J GOP0 9ACN CoA

Acetoacetyl-CoA

Hydroxymethyl glutaryl-CoA (HMG-CoA) Acetyl-CoA thiolase

HMG synthase

HMG reductase

Mevalonic acid 5-phosphate

Mevalonic acid 5-pyrophosphate

Isopentenyl pyrophosphate (IPP)

Dimethylallyl pyrophosphate FPP synthase

EA synthase EA dihydroxylase

MV decarboxylase

 

Nb-ABCG1/2

')6EM P@IQBQ _{20 µm}

<H>?;QN

#%

?L=:K'

<H>?;QN

'

JGOP0$*_: 2-3584

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/6F@!284

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?L=:K' Nb-ABCG2a-GFP

@DOQN

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76

6

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OH

HO

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R')S R')EMP@I Q BQ S

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6 .6

')6

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6+,

3

2 _FPP

2 ⁹ 2

Nb-ABCG1/2 ⁹

2 9 _{: GFP} A _Nb-

ABCG1/2^{2 A -}

1 1 _{2 EA}

synthase EA dihydroxylase, 2 Nb-ABCG1/2

2 2 9

1 _Nb-ABCG1/2

-

-A 1 2

9

: The Plant Cell

: Shibata, Y., Ojika, M., Sugiyama, A., Yazaki, K., Jones, D.A., Kawakita, K., and Takemoto, D. : The full-size ABCG transporters Nb-ABCG1 and Nb-ABCG2 function in pre- and post-invasion defense against Phytophthora infestans in Nicotiana benthamiana. DOI: 10.1105/tpc.15.00721