I am especially grateful to my major advisor, Dr. Naotaka Ishiguro, the professor of Laboratory of Food and Environmental Hygiene, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, for his mentoring during this journey. I would also like to thank my vice advisor, Dr. Yasuo Inoshima, the associate professor of Laboratory of Food and Environmental hygiene, Department of Veterinary medicine, Faculty of Applied Biological Sciences, Gifu University, for his advice and support in my academic activities. My appreciation is extended to all the Lab mates and students at Laboratory of Food and Environmental hygiene who were indispensible and provided excellent technical support which made this work possible.
My appreciation is extended to the other major advisory supervisors, Dr.
Hidefumi Furuoka, Laboratory of Pathological Science, Department of Veterinary Medical Science, Obihiro University of Agriculture and Veterinary Medicine, Dr.
Masanobu Goryo, Department of Veterinary Pathology, Faculty of Agriculture, Iwate University, Dr. Makoto Shibutani, Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, and Dr. Tokuma Yanai, Laboratory of Veterinary Pathology, Department of Veterinary Sciences, Faculty of Applied Biological Sciences, Gifu University, for their cooperation and constructive comments which improved this work.
In completion of my graduate school career, I would like to express sincere gratefulness and appreciation to the many people helping me along the way. I would like to thank my Egyptian mentors, Prof. Dr. Hosny A. Abdelrahman, Prof. Dr. Makram A. Yassein, Prof. Dr. Ali M. Ahmad and Prof. Dr. Hideki Hayashidani for all of their teachings, and guidance along my research journey from the beginning till the completion of my project. Furthermore, I would like to thank them for always pushing me to achieve my best.
This work was supported in part by grants from the Ministry of Education, Culture, Sports, Science, and Technology, and the Ministry of Health, Labour and Welfare of Japan. This work was also supported in part by a grant from the Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science.
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Finally, I want to thank my family members, especially my wife, for the support they have provided me throughout my graduate school career. To my mother and the soul of my father, I am eternally grateful for their support. I would like to thank them for everything they sacrificed to leave our home country of Egypt to this country, which ultimately provided me with this opportunity to succeed and become the person I am today.
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