抗糖鎖抗体
Carbohydrate chains are called the third life chain
following the protein and the nucleic acid and are one of
the most important issues in the post genome research.
Tokyo Chemical Industry Co. LTD. (TCI) supports
glycoscience research by providing useful
anti-carbohydrate chain antibodies.
Most carbohydrate chains attach to lipids or proteins
and occur in the form of glycoproteins or glycolipids
(N-glycan, O-glycan, proteoglycans and others).
Carbohydrate chains are known to be expressed on brain,
nerve, cancer, and endothelial cells. Some carbohydrate
chains are known to relate to diseases (e.g., cancer,
Alzheimer's disease, Guillain-Barré syndrome, Lysosome
syndrome such as Fabry disease, gangliosidosis),
differentiation and development (iPS/ES cells).
Antibodies are proteins which are one of the
components of the immune system. The specificity of
antibodies is likened to the interaction between a key and
a keyhole. Antibodies are useful reagents for research in
many scientific disciplines including life science and
diagnostic reagents.
Anti-carbohydrate antibodies can recognize glycolipids
or glycoproteins. TCI mainly produces antibodies against
glycolipids; ganglio series, globo series, lacto series, and
neo-lacto series.
These antibodies can be used for immunohistochemistry,
cell-staining, inhibition assay for cell adhesion, flow
cytometry, ELISA, TLC-immunostaining and other methods.
TCI antibodies are very useful tools for analyzing the
expression of carbohydrate chains and their functions.
Labeled anti-carbohydrate chain antibodies will also be
available soon.
ELISA, Cell ELISA Western blotting
TLC-immunostaining
糖鎖は，生命第3の鎖としてその生物機能が重要視され，ポ ストゲノム研究の一端を担う領域として注目されています。
TCIでは，ポストゲノム時代の糖鎖研究に有用な抗糖鎖抗体で お客様の研究をサポート致します。
多くの糖鎖は，脂質やタンパク質などに結合し，糖脂質あ るいは糖タンパク質（N型，O型，プロテオグリカンなど）と して存在しています。糖鎖は，脳，神経，癌細胞，血管内皮細 胞などに存在することが知られており，iPS/ES細胞，癌，ア ルツハイマー，ギランバレー症候群，ファブリー病やガングリ オシドーシスなどのリソソーム病などの疾患，発生，分化など で重要な役割を担うと考えられ，その重要性が注目されていま す。
抗体は，免疫系を構成するタンパク質で，対応する抗原と鍵 と鍵穴の関係のように高い特異性で結合します。抗体は，その 高い特異性から生命科学の研究や診断薬の検出系として活用さ れています。
抗糖鎖抗体は，糖脂質，糖タンパク質などの糖鎖を特異的 に認識できる抗体です。東京化成工業では，抗糖鎖抗体の中で もガングリオ系，グロボ系，ラクト系，ネオラクト系などの糖 脂質に関連する抗体を中心に品揃えしています。東京化成工業 の抗糖鎖抗体は，細胞，組織，生体試料での糖鎖（抗原）の局 在，疾患や発生，分化過程での糖鎖の変化などを調べるツール として有用で，組織染色，細胞染色，細胞接着阻害研究，フ ローサイトメトリー，ELISA，TLC免疫染色などの幅広い用 途でご使用いただけます。
また，各種標識した抗糖鎖抗体の製品化も予定していま す。
Anti-Glyco Antibodies
New
A2586 Anti-Gb
3 Monoclonal Antibody
(Culture Supernatant) Price on request
New
A2507 Anti-GD
1a Monoclonal Antibody 1vial New
A2508 Anti-GD
1b Monoclonal Antibody 1vial New
A2580 Anti-GD
3 Monoclonal Antibody Price on request New
A2579 Anti-GD
3 Monoclonal Antibody (Culture Supernatant)
Price on request New
A2505 Anti-GM
1 Monoclonal Antibody 1vial New
A2506 Anti-Gb
3 Monoclonal Antibody Price on request New
Anti-Glyco Antibodies- ①
A2575 Anti-GM
2 Monoclonal Antibody
(Culture Supernatant) Price on request
New
A2582 Anti-GM
3 Monoclonal Antibody Price on request New
A2581 Anti-GM
3 Monoclonal Antibody (Culture Supernatant)
Price on request New
A2578 Anti-Lewis X Monoclonal Antibody Price on request New
A2577 Anti-Lewis X Monoclonal Antibody (Culture Supernatant)
Price on request New
A2510 Anti-Lewis Y Monoclonal Antibody Price on request New
A2576 Anti-GM
2 Monoclonal Antibody Price on request New
Anti-Glyco Antibodies- ②
A2509 Anti-Sialyl Lewis A Monoclonal
Antibody (2D3) 1vial
New
A2584 Anti-Sialyl Lewis A Monoclonal
Antibody (1H4) Price on request
New
A2583 Anti-Sialyl Lewis A Monoclonal Antibody (1H4)
(Culture Supernatant)
Price on request New
A2587 Anti-Lewis Y Monoclonal Antibody
(Culture Supernatant) Price on request
New
Anti-Glyco Antibodies- ③
G0407 Goat Anti-Mouse IgG HRP Conjugate Price on request New
G0406 Goat Anti-Mouse IgG FITC Conjugate Price on request
New
