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Department of Microbiology and Infectious Diseases, Toho University

School of Medicine

* Department of Laboratory Medicine, Toho University Omori Medical Center

NAOKIWATANABEand MASAAKISHINAGAWA Department of Clinical Laboratory

Medicine, Division of Laboratory Diagnosis, Sapporo Medical University

School of Medicine

MINORUYASUJIMA

Department of Laboratory Medicine, Hirosaki University Graduate

School of Medicine

AKIRASUWABEand MAKIKOKURODA* Department of Laboratory Medicine,

Iwate Medical University School of Medicine

* Department of Central Clinical Laboratories, Iwate Medical University

Hospital

MITSUOKAKUand MIHOKITAGAWA Department of Infection Control and

Laboratory Diagnostics, Tohoku University Graduate School of Medicine

KEIJIKANEMITSUand YUJIIMAFUKU

Department of Clinical Laboratory Medicine, Fukushima Medical University

MASAMIMURAKAMIand SACHIEYOMODA* Department of Clinical Laboratory Medicine, Gunma University Graduate

School of Medicine

* Clinical Laboratory Center,

TOSHIYUKIYAMADA Department of Clinical Laboratory Medicine, Jichi Medical University,

School of Medicine

FUMIONOMURA

Division of Laboratory Medicine, Chiba University Hospital

HARUSHIGEKANNO

Department of Internal Medicine, Takane Hospital

SHIGEFUMIMAESAKIand GIICHIHASHIKITA* Department of Infectious Disease &

Infection Control, Saitama Medical School

* Department of Laboratory Medicine, Saitama Medical School

SHIGEMIKONDOand SHIGEKIMISAWA* Department of Clinical Pathology, Juntendo University School of Medicine

* Department of Clinical Laboratory, Juntendo University Hospital

HAJIMEHORIUCHIand YOKOTAZAWA

Clinical Laboratory, NTT Medical Center, Tokyo

HIDEKINAKASHIMAand HIROMUTAKEMURA

Department of Microbiology, St. Marianna University School of Medicine

MASAHIKOOKADAand YOSHINORIHORIKAWA*

Division of Clinical Preventive Medicine, Niigata University

* Clinical Laboratory Division, Niigata

MASATOMAEKAWAand OSANORINAGURA* Department of Laboratory Medicine,

Hamamatsu University School of Medicine

* Hamamatsu University School of Medicine University Hospital, Clinical

Laboratory Department of Laboratory Medicine

TETSUYAYAGIand HISASHIBABA

Department of Infectious Diseases, Nagoya University Hospital

SHIOMIISHIGO

Clinical Laboratory, Ogaki Municipal Hospital

NAOHISAFUJITAand TOSHIAKIKOMORI* Department of Infection Control and Laboratory Medicine, Kyoto Prefectural

University of Medicine

* Department of Clinical Laboratory, Kyoto Prefectural University of Medicine

SATOSHIICHIYAMA

Department of Clinical Laboratory Medicine, Kyoto University Graduate

School of Medicine

KIYOHARUYAMANAKAand YOKOMURATA Division of Clinical Laboratory,

Otemae Hospital

SHUJIMATSUOand HISASHIKOHNO

Department of Clinical Pathology, Tenri Hospital

SEIJIKAWANOand SHOHIROKINOSHITA

Clinical Laboratory, Kobe University Hospital

TOMOHIKOTAMINATOand KIYOSHI

NEGAYAMA

Department of Clinical Laboratory, Kagawa University Hospital

MITSUHARUMURASEand HITOSHI

MIYAMOTO

Division of Medical Technology, Ehime University Hospital

NOBUCHIKAKUSANOand MOTOKONOSE Department of Central Clinical Laboratory, Okayama University Hospital

MICHIYAYOKOZAKIand HIDEYUKIITAHA* Division of Clinical Laboratory Medicine,

Hiroshima University Hospital

* Department of Clinical Laboratory Medicine, Hiroshima University Hospital

AKIRAMATSUNAGAand HISAEYOSHIMURA

Clinical Laboratory, Fukuoka University Hospital

SHIGERUKOHNO, KATSUNORI

YANAGIHARA* and JUNICHIMATSUDA* Second Department of Internal Medicine,

Nagasaki University Hospital

* Department of Laboratory Medicine, Nagasaki University Hospital

TETSUNORISAIKAWAand KAZUFUMI HIRAMATSU

Clinical Laboratory Center, Oita University Hospital

The antibacterial activity of meropenem (MEPM) and other parenteral antibiotics against clini-cal isolates of 2655 strains including 810 strains of positive bacteria, 1635 strains of Gram-negative bacteria, and 210 strains of anaerobic bacteria obtained from 30 medical institutions during 2009 was examined. The results were as follows;

1. MEPM was more active than the other carbapenem antibiotics tested against Gram-nega-tive bacteria, especially against enterobacteriaceae and Haemophilus influenzae. MEPM was also active against most of the species tested in Gram-positive and anaerobic bacteria, except for multi-drug resistant strains including methicillin-resistant Staphylococcus aureus(MRSA).

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