[PDF] Top 20 株主通信 2011年3月期（2010年度） 第58期 以前｜[財務情報] IR資料ライブラリー｜＜株主・投資家の皆さまへ＞ IR情報｜NIPRO－ニプロ株式会社－ 「その技術は、人のために。」
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Cytochrome P450-dependent monooxygenase system and anesthetics.
... The cytochrome P450-dependent monooxygenases constitute the primary enzyme system responsible for the oxidative metabolism of a variety of xenobiotics and endogenous compounds ... 完全なドキュメントを参照
1
Induction and inhibition of cytochrome P450-dependent monooxygenase in hamster tissues by ethanol.
... hepatic and extrahepatic monooxygenases were determined in the present ...increased cytochrome P-450 (P-450) content and monooxygenase activities towards aniline, ... 完全なドキュメントを参照
1
Induction and suppression of renal and hepatic cytochrome P450-dependent monooxygenase by acute and chronic streptozotocin diabeties in hamsters.
... FP and Ueng TH 摘要 Abstract The acute and chronic effects of streptozotocin diabetes on kidney and liver microsomal monooxygenases were studied using hamsters 2 days and 6 weeks following ... 完全なドキュメントを参照
2
Human cytochrome P450 monooxygenase system is suppressed by propofol. 1995; 74: 558-562.
... We have studied the effect of propofol on the cytochrome P450-dependent mono-oxygenase system in human liver microsomes by assaying mono-oxygenase activities toward specific cytochrome [r] ... 完全なドキュメントを参照
4
Metabolic characteristics and enflurane defluorination of cytochrome P450-dependent monooxygenases in human hepatocellular carcinoma.
... 2B1, and 2E1 were evaluated in vitro by reacting with the specific marker substrates benzo(a)pyrene, benzphetamine and aniline, respectively, in the generating incubation ...tissues and tissues from ... 完全なドキュメントを参照
2
Difference between in vivo and in vitro effects of propofol on defluorination and metabolic activities of hamster hepatic cytochrome P450-dependent monooxygenases.
... vivo and in vitro effects of propofol on cytochrome P450-dependent monooxygenase activities in hamster liver ...induce cytochrome P450 ...the ... 完全なドキュメントを参照
4
Propofol inhibis renal cytochrome P450 activity and enflurane defluorination in vitro in hamsters.
... binding and affecting its drug ...sufentanil and alfentanil in the liver may be inhibited by ...rat and in our human liver model demonstrated that interference in oxidative metabo- lism by propofol ... 完全なドキュメントを参照
10
Propofol inhibis renal cytochrome P450 activity and enflurane defluorination in vitro in hamsters.
... erythromycin and pentoxyresorufin, for cytochrome P450 2E1 , 1A1, 3A4 and 2B1 , ...aniline and benzo(a)pyrene hydroxylase within kidney microsomes was related to propofol ... 完全なドキュメントを参照
2
Induction of cytochrome P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5
... O-deethylation, and 7-ethoxycoumarin O-deethylation activities of S9 ...to P450s 1A1 and ...induced P450s 1A1 and 1B1 mRNA levels in CL5 ...on P450 ... 完全なドキュメントを参照
1
Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene
... The monooxygenase system is consisted of a mul- tiplicity of P450 hemoproteins, a flavoprotein NADPH-cytochrome P450 reductase, and phos- ...the P450 ... 完全なドキュメントを参照
1
Induction of cytochrome P450 1A1 and 1B1 in human lung adenocarcinoma CL5 cells by frying-meat emission particulate.
... The effect of airborne frying-meat emission particulate (FMEP) on cytochrome P450 (P450)-dependent monooxygenase was determined using human lung adenocarcinoma cell line CL5 treated wit[r] ... 完全なドキュメントを参照
1
cytochrome P450
... 入不含維生素 C 的純化飼料，再分別添加 300ppm 維生素 C 作為 F300、D300 組 的飼料，餵養剛離乳之雄性天竺鼠，共為期 17 週。結果顯示，炸油組(D300)生 長及攝食效率較差，血漿及肝腎組織中維生素 C 含量均明顯低於 F300 組，而肝、 腎組織中 TBARS(Thiobarbituric acid reactive substances)含量較高。餵食炸油之天 竺鼠肝中 ... 完全なドキュメントを参照
Physiological and pathophysiological regulation of cytochrome P450.
... Approaches and systems used to address these questions included conditional gene knockouts in mice, primary hepatocyte cultures, immunofluorescence imaging of cells, and cell lines sta[r] ... 完全なドキュメントを参照
1
Induction of cytochrome P450-dependent monooxygenases in hamster tissues by fasting.
... kidney, and lung monooxygenases were studied using hamsters starved for 4 ...microsomal cytochrome P450 content and NADPH-cytochrome P450 reductase activity in ... 完全なドキュメントを参照
3
Developing and evaluating the HRM technique for identifying cytochrome P450 2D6 polymorphisms
... populations, and we found eight genetic variants including one novel polymorphism, six alleles, and ten ...N and *41 alleles, all of which decrease the activity of CYP2D6, occur among the Chinese ... 完全なドキュメントを参照
12
Potential Risk of Mulberry-Drug Interaction: Modulation on P-glycoprotein and Cytochrome P450 3A
... kidney and liver in transplant patients, have been reported because patients combined the use of CSP with P-gp or CYP 3A4 inducers, such as St John's Wort (26) ...of P-gp and/or CYP ... 完全なドキュメントを参照
2
The role of cytochrome P450 in herb-drug interactions.
... Polymorphic P450 regulation and expression and environmental exposure are the main causes of variability in human response to xenobiotic modulatory ...physicians and pharmacists are ... 完全なドキュメントを参照
1
Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response
... week) and anxiolytics (lorazepam 1–2 mg per day) for severe ...4 and 8 and sent to a central laboratory for analy- ses of S-CIT and its metabolites, and for DNA ...dosage and ... 完全なドキュメントを参照
27
Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma
... (BPN) and 2,7-bis( 1H -indol-2-yl)ethynyl-1,8-naphthyridine (BIN) adopting daad relays of proton donors ( d ) and acceptors ( a ) form multiple hydrogen-bonding complexes with various monosaccharides that ... 完全なドキュメントを参照
2
Cytochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers
... positive and HBsAg-negative controls Ninety-eight percent of the study subjects reported that their father and mother had the same ethnic ...HBsAg-positive and HBsAg-negative control subjects by ... 完全なドキュメントを参照
2
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