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Antithrombotic effect of PMC, a potent alpha- tocopherol analogue on platelet plug formation in vivo.
... Abstract Platelet thrombi formation was induced by irradiation of mesenteric venules with filtered light in mice pretreated intravenously with fluorescein ...sodium. PMC (2, 2, 5, 7, ... 完全なドキュメントを参照
Antithrombotic effect of PMC, a potent alpha-tocopherol analogue on platelet plug formation in vivo.
... Abstract Platelet thrombi formation was induced by irradiation of mesenteric venules with filtered light in mice pretreated intravenously with fluorescein ...sodium. PMC (2, 2, 5, 7, ... 完全なドキュメントを参照
Antithrombotic effect of PMC, a potent a-tocopherol analogue on platelet plug formation
... Platelet thrombi formation was induced by irradiation of mesenteric venules with filtered light in mice pretreated intravenously with fluorescein sodium.. PMC (2, 2, 5, 7,.[r] ... 完全なドキュメントを参照
2
Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments.
... metallothionein may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown and thromboxane A2 formation, thereby leading to inhibition of intra[r] ... 完全なドキュメントを参照
2
Morphine-potentiated platelet aggregation in in vivo and platelet plug formation in in vivo experiments.
... We concluded that morphine may exert its potentiation in platelet aggregation by binding to alpha(2)-adrenoceptors in human platelets, with a resulting inhibition of adenylate cyclase,[r] ... 完全なドキュメントを参照
10
Morphine-potentiated platelet aggregation in in vitro and platelet plug formation in in vivo experiments
... Morphine concentration depen- dently (0.6, 1, and 5 gM) potentiated platelet aggregation and the ATP release reaction stimulated by agonists (i.e., collagen and U46619) in wa[r] ... 完全なドキュメントを参照
19
Morphine-potentiated platelet aggregation in in vitro and platelet plug formation in in vivo experiments
... pathways in platelets remain ...influence of morphine on washed human platelets. In this study, washed human platelet suspensions were used for in vitro ...Furthermore, ... 完全なドキュメントを参照
10
The antiplatelet activity of PMC, a potent a-tocopherol analogue, is mediated through inhibition of cyclooxygenase. Br.
... breakdown in human platelets stimulated by collagen.PMC (10 and 25μM) significantly inhibited collagen-stimulated thromboxane A2 (TxA2) formation in human ...platelets. On the ... 完全なドキュメントを参照
The antiplatelet activity of PMC, a potent a-tocopherol analogue, is mediated through inhibition of cyclooxygenase. Br.
... breakdown in human platelets stimulated by collagen.PMC (10 and 25μM) significantly inhibited collagen-stimulated thromboxane A2 (TxA2) formation in human ...platelets. On the ... 完全なドキュメントを参照
Comparison of the relative activities of a-tocopherol and PMC on platelet aggregation and antioxidative activity.
... (DPH). PMC is about 6-times more potent than alpha-tocopherol on this ...activity of PMC was investigated using two in vitro models. PMC inhibited ... 完全なドキュメントを参照
2
Comparison of the relative activities of a-tocopherol and pmc on platelet aggregation and antioxidative activity.
... Abstract In this study, PMC (2,2,5,7,8-pentamethyl-6-hydroxychromane), a potent antioxidant derived from alpha-tocopherol, dose-dependently inhibited agonist- induced ... 完全なドキュメントを参照
Comparison of the relative activities of a-tocopherol and pmc on platelet aggregation and antioxidative activity.
... The concentration of PMC resulting in a decrease of 0.20 in the absorbance of DPPH was about 12.1+/-3.6 microM, was comparable in potency to alpha-tocopherol, butylated hydroxytoluence[r] ... 完全なドキュメントを参照
Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia-reperfusion: reduced neutrophil activation and anti-oxidant actions
... most potent analogue of α-tocopherol for ...has potent free radical-scavenging activity. In the present study, PMC significantly attenuated middle cerebral artery ... 完全なドキュメントを参照
3
Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia-reperfusion: reduced neutrophil activation and anti-oxidant actions.
... most potent analogue of α-tocopherol for ...has potent free radical-scavenging activity. In the present study, PMC significantly attenuated middle cerebral artery ... 完全なドキュメントを参照
1
Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation
... These results indicate that the antiplatelet activity of lycopene may involve the following pathways: (1) Lycopene may inhibit the activation of phospholipase C, followed by inhibition[r] ... 完全なドキュメントを参照
3
Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation.
... diseases. In this study, we evaluated the inhibition of thrombus forma- tion by lycopene in vivo and found that lycopene sig- nificantly prevented platelet-plug ...formed ... 完全なドキュメントを参照
1
Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation.
... These results indicate that the antiplatelet activity of lycopene may involve the following pathways: (1) Lycopene may inhibit the activation of phospholipase C, followed by inhibition[r] ... 完全なドキュメントを参照
2
Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation.
... These results indicate that the antiplatelet activity of lycopene may involve the following pathways: (1) Lycopene may inhibit the activation of phospholipase C, followed by inhibitio[r] ... 完全なドキュメントを参照
Antithrombotic effects of tetramethylpyrazine in in vivo experiments
... Continuous infusion of TMPZ (1 μg/g per min) for 10 minutes also significantly increased the bleeding time approximately 1.6-fold, and the bleeding time returned to baseline within 60 [r] ... 完全なドキュメントを参照
2
Antithrombotic effects of magnesium sulfate in in vivo experiments.
... Abstract In this study, magnesium sulfate was effective in reducing the mortality of adenosine diphosphate—induced acute pulmonary thromboembolism in mice, when it was administered ... 完全なドキュメントを参照
2
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