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The antiplatelet activity of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, is mediated through inhibition of phospholipase C.
... to the inhiother hand, rutaecarpine (50 and 100 mM) dose- bition of phospholipase C activity, leading to redependently inhibited the increase in intracellular duce ... 完全なドキュメントを参照
The antiplatelet activity of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, is mediated through inhibition of phospholipase C.
... study, the mechanism involved in the anti- affect nitrate production in collagen (10 mg/ml)-platelet activity of rutaecarpine in human platelet induced human platelet ...On the ... 完全なドキュメントを参照
The antiplatelet activity of rutaecarpine, an alkaloid isolated from evodia rutaecarpa, is mediated through inhibition of phospholipase C.
... It is concluded that the antiplatelet activity of rutaecarpine may possibly be due to the inhibition of phospholipase C activity, leading to reduce phosphoinositide breakdown, followed[r] ... 完全なドキュメントを参照
2
Cardiovascular Pharmacological Actions of Rutaecarpine, a Quinazolinocarboline Alkaloid Isolated From Evodia rutaecarpa
... Therefore, rutaecarpine induced an endothelium/NO-depen- dent vasodilatation in rat aorta precontracted by ...by the removal of extracellular Ca 2 þ in the ...by rutaecarpine ... 完全なドキュメントを参照
1
Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from evodia rutaecarpa. Eur.
... In addition, rutaecarpine (40-200 microM) did not significantly affect cyclic AMP and cyclic GMP levels in human washed platelets, whereas it significantly inhibited thromboxane B2 for[r] ... 完全なドキュメントを参照
3
α-Naphthoflavone, a Potent Antiplatelet Flavonoid, Is Mediated through Inhibition of Phospholipase C Activity and Stimulation of Cyclic GMP Formation
... (1) α-NF may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown, protein kinase C activation, and thromboxane A2 formation, thereby leading[r] ... 完全なドキュメントを参照
4
Alteration of the pharmacokinetics of the theophylline by rutaecarpine, an alkaloid of the medical herb Evodia rutaecarpa, inrats
... Abstract Rutaecarpine is the main active alkaloid present in the medicinal herb, Evodia rutaecarpa [Tetradium ...ruticarpum]. The cytochrome P450 (CYP) 1A2 ... 完全なドキュメントを参照
1
alpha-Naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
... (1) alpha-NF may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown, protein kinase C activation, and thromboxane A(2) formation, thereby l[r] ... 完全なドキュメントを参照
2
Alpha-naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
... alpha-NF (5 and 10 microM) inhibited intracellular Ca(2+) mobilization, phosphoinositide breakdown, and thromboxane A(2) formation stimulated by collagen (1 microg/mL) in human platele[r] ... 完全なドキュメントを参照
Alpha-naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
... (1) alpha-NF may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown, protein kinase C activation, and thromboxane A(2) formation, thereby l[r] ... 完全なドキュメントを参照
Alternation of the pharmacokinetics of theophyline by rutaecarpine, an alkaloid of the medical herb Evodia rutaecarpa, in rats.
... EROD activity. In the lungs, EROD activity was elevated from an undetectable to a detectable level by ...parameters of theophylline were determined using a microdialysis sampling ... 完全なドキュメントを参照
Alternation of the pharmacokinetics of theophyline by rutaecarpine, an alkaloid of the medical herb Evodia rutaecarpa, in rats.
... evaluate the pharmacokinetic interaction of theophylline with rutaecarpine, the effects of rutaecarpine on CYP1A2 activity and theophylline pharmacokinetics were ... 完全なドキュメントを参照
The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.
... Furthermore, TMPZ concentration (50 and 200m M)- and time (15 and 30 min)-dependently triggered endothelial- type constitutive nitric oxide synthase (ecNOS) protein expr[r] ... 完全なドキュメントを参照
The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.
... Furthermore, TMPZ concentration (50 and 200m M)- and time (15 and 30 min)-dependently triggered endothelial- type constitutive nitric oxide synthase (ecNOS) protein expression in huma[r] ... 完全なドキュメントを参照
The Antiplatelet activity of ketamine is mediated through suppression of phosphoinositide breakdown and an increase in cyclic GMP.
... In this study, Escherichia coli LPS dose-dependently (100-500 μg/ ml) and time- dependently (10-60 min) inhibited platelet aggregation in human and rabbit platelets stimulated by agonis[r] ... 完全なドキュメントを参照
The Antiplatelet activity of ketamine is mediated through suppression of phosphoinositide breakdown and an increase in cyclic GMP.
... coli LPS may be involved in the activation of a nitric oxide/cyclic GMP pathway in platelets, resulting in inhibition of platelet aggregation. Therefore, LPS-mediated alteration of pla[r] ... 完全なドキュメントを参照
The antiplatelet activity of PMC, a potent a-tocopherol analogue, is mediated through inhibition of cyclooxygenase. Br.
... inhibited the intracellular Ca2+ mobilization, whereas it did not inhibit phosphoinositide breakdown in human platelets stimulated by ...On the other hand, PMC (25 and 100μM) did not increase the ... 完全なドキュメントを参照
The antiplatelet activity of PMC, a potent a-tocopherol analogue, is mediated through inhibition of cyclooxygenase. Br.
... inhibited the intracellular Ca2+ mobilization, whereas it did not inhibit phosphoinositide breakdown in human platelets stimulated by ...On the other hand, PMC (25 and 100μM) did not increase the ... 完全なドキュメントを参照
Antiplatelet activity of Staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway
... In this study, Gram-positive Staphylococcus aureus lipoteichoic acid (LTA) dose dependently (0.1-1.0 microg/mL) and time dependently (10-60 min) inhibited platelet aggregation in human[r] ... 完全なドキュメントを参照
2
Antiplatelet activity of staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway
... Sheu JR;Hsiao G;Lee CR;Chang WC;Lee LW;Su CH and Lin CH Abstract In this study, Gram-positive Staphylococcus aureus ence Ltd. All rights reserved. lipoteichoic acid (LTA) dose dependently (0.1–1.0 mg/mL) and time ... 完全なドキュメントを参照
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