系統名生産コロニー引佐引佐 SPFマウス大原引佐春野引佐春野引佐春野 Slc:ddY I28 Slc:ICR I57 A/JJmsSlc O35 AKITA/Slc I22 AKR/NSlc H34 BALB/cCrSlc I34 H34 I24 H24 検査日 4/14, 4/29 4/6, 4

(1)

A/JJmsSlc AKITA/Slc AKR/NSlc

引佐引佐大原引佐春野引佐春野引佐春野

I28 I57 O35 I22 H34 I34 H34 I24 H24

4/14 , 4/29 4/6 , 4/22 4/12 , 4/28 4/15 , 4/29 4/28 4/12 4/28 4/1 , 4/16 4/14 , 4/29 検査項目 6w , Re 6w , Re 6w , Re 6w , Re 6w , Re 7w 6w , Re 6w , Re 6w , Re Pseudomonas aeruginosa 毎月 ○ _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10 Citrobacter rodentium 毎月 ○ _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10 Salmonella spp. 毎月 ○ _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10 Salmonella typhimurium 毎月 □ _0/40 _0/20 _0/40 _0/20 _0/5 _0/5 _0/5 _0/10 _0/10 Pasteurella pneumotropica 毎月 ○ _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10 Corynebacterium kutscheri 毎月 ○ _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10 毎月 □ _0/40 _0/20 _0/40 _0/20 _0/5 _0/5 _0/5 _0/10 _0/10 Clostridium piliforme 毎月 ■ _0/40 _0/20 _0/40 _0/20 _0/5 _0/5 _0/5 _0/10 _0/10 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _0/10 _0/10 _0/10 _0/10 _* _0/5 _* _0/10 _* Helicobacter bilis 3ヶ月毎 ▲ _0/10 _0/10 _0/10 _0/10 _* _0/5 _* _0/10 _* Mycoplasma pulmonis 毎月 ○ _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10 毎月 ■ 0/40 0/20 0/40 0/20 0/5 0/5 0/5 0/10 0/10

Mouse hepatitis virus 毎月 ■ _0/40 _0/20 _0/40 _0/20 _0/5 _0/5 _0/5 _0/10 _0/10

Sendai virus 毎月 ■ _0/40 _0/20 _0/40 _0/20 _0/5 _0/5 _0/5 _0/10 _0/10

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/20 _0/10 _0/20 _0/10 _0/5 _0/5 _0/5 _0/10 _0/10

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Ectromelia virus 3ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Murine norovirus 12ヶ月毎 ▲ _* _* _* _* _* _* _* _* _*

Minute virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Pinworm 毎月 ● _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10

Intestinal protozoa 毎月 ● _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10

Ectoparasites 毎月 ● _0/50 _0/30 _0/50 _0/30 _0/5 _0/5 _0/5 _0/10 _0/10

Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* _* _*

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested 系統名

生産コロニー

検査日週齢

SPFマウス

(2)

BXSB/MpJJmsSlc-Yaa B10.A/SgSnSlc B10.BR/SgSnSlc B10.D2/nSnSlc B10.S/SgSlc C57BL/10SnSlc CBA/NSlc C3H/HeSlc 春野春野春野春野春野春野春野春野 H34 H32 H32 H32 H32 H32 H34 H24 4/5 4/8 4/1 4/1 4/26 4/1 4/5 4/29 検査項目 6w 6w , Re 6w , Re 6w , Re 6w , Re 6w , Re 6w , Re 6w , Re Pseudomonas aeruginosa 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Citrobacter rodentium 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Salmonella spp. 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Salmonella typhimurium 毎月 □ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Pasteurella pneumotropica 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Corynebacterium kutscheri 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 毎月 □ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Clostridium piliforme 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _* _* _* _* _* _* _* _* Helicobacter bilis 3ヶ月毎 ▲ _* _* _* _* _* _* _* _* Mycoplasma pulmonis 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 毎月 ■ 0/5 0/5 0/5 0/5 0/5 0/5 0/5 0/5

Mouse hepatitis virus 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Sendai virus 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _* _*

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _* _* _* _* _* _*

Ectromelia virus 3ヶ月毎 ■ _* _* _* _* _* _* _* _*

Murine norovirus 12ヶ月毎 ▲ _* _* _* _* _* _* _* _*

Minute virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _* _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* _* _* _* Pinworm 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Intestinal protozoa 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Ectoparasites 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* _* Note: 判定：異常なし

生産コロニー

検査日週齢

(3)

C3H/HeJYokSlc C3H/HeNSlc C57BL/6JHamSlc-ob C57BL/6JJmsSlc-lpr /lpr 春野春野引佐春野引佐春野春野春野 H34 H34 I34 H31 I32 H23 H34 H32 4/12 4/20 4/2 , 4/19 4/7 , 4/22 4/5 , 4/19 4/6 , 4/22 4/12 4/1 検査項目 6w , Re 6w , Re 7w , Re 6w , Re 6w , Re 6w , Re 6w , Re 8w Pseudomonas aeruginosa 毎月 ○ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Citrobacter rodentium 毎月 ○ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Salmonella spp. 毎月 ○ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Salmonella typhimurium 毎月 □ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Pasteurella pneumotropica 毎月 ○ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Corynebacterium kutscheri 毎月 ○ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 毎月 □ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Clostridium piliforme 毎月 ■ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _* _* _0/10 _* _0/10 _* _* _* Helicobacter bilis 3ヶ月毎 ▲ _* _* _0/10 _* _0/10 _* _* _* Mycoplasma pulmonis 毎月 ○ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 毎月 ■ 0/5 0/5 0/10 0/10 0/10 0/10 0/5 0/5

Sendai virus 毎月 ■ _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* _* _* _* Pinworm 毎月 ● _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Intestinal protozoa 毎月 ● _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Ectoparasites 毎月 ● _0/5 _0/5 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5 Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* _* 系統名

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested

C57BL/6NCrSlc C57BL/6JJmsSlc 生産コロニー

検査日週齢

(4)

DBA/1JJmsSlc DBA/2CrSlc HIGA/NscSlc MRL/MpJJmsSlc-lpr /lpr NC/NgaSlc SAMP1/SkuSlc SAMP8/TaSlc 春野春野大原春野春野春野春野 H31 H34 O3 H32 H32 H32 H32 4/13 4/5 4/16 4/8 4/1 4/26 4/19 検査項目 6w , Re 6w , Re Re 8w 6w , Re 6w , Re 6w , Re Pseudomonas aeruginosa 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Citrobacter rodentium 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Salmonella spp. 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Salmonella typhimurium 毎月 □ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Pasteurella pneumotropica 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Corynebacterium kutscheri 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 毎月 □ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Clostridium piliforme 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _* _* _0/5 _* _* _* _* Helicobacter bilis 3ヶ月毎 ▲ _* _* _0/5 _* _* _* _* Mycoplasma pulmonis 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 毎月 ■ 0/5 0/5 0/5 0/5 0/5 0/5 0/5

Mouse hepatitis virus 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Sendai virus 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _*

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _* _* _* _* _*

Ectromelia virus 3ヶ月毎 ■ _* _* _* _* _* _* _*

Murine norovirus 12ヶ月毎 ▲ _* _* _* _* _* _* _*

Minute virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _* _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* _* _* Pinworm 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Intestinal protozoa 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Ectoparasites 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* Note: MRL/MpJJmsSlc-lpr /lpr は、血清反応のみ同室のB10.A/SgSnSlcを用いております。 判定：異常なし週齢

生産コロニー

検査日

(5)

SAMP10/TaIdrSlc SAMR1/TaSlc 129X1/SvJJmsSlc B6D2F1/Slc B6C3F1/Slc CB6F1/Slc CD2F1/Slc NZBWF1/Slc 春野春野春野春野春野春野春野春野 H32 H32 H32 H24 H24 H24 H24 H34 4/26 4/19 4/8 4/7 4/7 4/22 4/14 4/12 検査項目 6w , Re 6w , Re 6w , Re 6w 6w 6w 6w 6w Pseudomonas aeruginosa 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Citrobacter rodentium 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Salmonella spp. 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Salmonella typhimurium 毎月 □ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Pasteurella pneumotropica 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Corynebacterium kutscheri 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 毎月 □ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Clostridium piliforme 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _* _* _* _* _* _* _* _* Helicobacter bilis 3ヶ月毎 ▲ _* _* _* _* _* _* _* _* Mycoplasma pulmonis 毎月 ○ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 毎月 ■ 0/5 0/5 0/5 0/5 0/5 0/5 0/5 0/5

Sendai virus 毎月 ■ _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* _* _* _* Pinworm 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Intestinal protozoa 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Ectoparasites 毎月 ● _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 _0/5 Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* _* 0/5 * H32 4/26 SPFマウス WBB6F1/Kit-KitW_/KitW-v_/Slc 春野生産コロニー検査日 * * 週齢 8w 系統名 0/5 0/5 * 0/5 0/5 * 0/5 0/5 0/5 0/5 0/5 0/5 0/5

* 0/5 0/5 * 0/5 * * 0/5 * * *

(6)

C57BL/6-Tg(CAG-EGFP) C57BL/6JJmsSlc-Tg(gpt delta) KSN/Slc 大原大原大原春野春野 O2 O2 O5 H35 H35 4/13 4/5 4/1 , 4/19 4/13 , 4/27 4/21 検査項目 Re Re 6w , Re 6w , Re 12w , 18w Pseudomonas aeruginosa 毎月 ○ _0/5 _0/3 _0/10 _0/12 _0/3 Citrobacter rodentium 毎月 ○ _0/5 _0/3 _0/10 _0/12 _0/3 Salmonella spp. 毎月 ○ _0/5 _0/3 _0/10 _0/12 _0/3 Salmonella typhimurium 毎月 □ _0/5 _0/3 _0/10 _0/12 _0/6 Pasteurella pneumotropica 毎月 _○ _0/5 _0/3 _0/10 _0/12 _0/3 Staphylococcus aureus 毎月 ○ －－ _0/10 _0/12 _0/3 Corynebacterium kutscheri 毎月 _○ _0/5 _0/3 _0/10 _0/12 _0/3 毎月 □ _0/5 _0/3 _0/10 _0/12 _0/6 Clostridium piliforme 毎月 ■ _0/5 _0/3 _0/10 _0/12 _0/6 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _0/5 _0/3 _0/10 _0/12 _0/3 Helicobacter bilis 3ヶ月毎 ▲ _0/5 _0/3 _0/10 _0/12 _0/3 Mycoplasma pulmonis 毎月 ○ _0/5 _0/3 _0/10 _0/12 _0/3 毎月 _■ _0/5 _0/3 _0/10 _0/12 _0/6

Mouse hepatitis virus 毎月 ■ _0/5 _0/3 _0/10 _0/12 _0/6

Sendai virus 毎月 ■ 0/5 0/3 0/10 0/12 0/6

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _* _* _*

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/5 _0/3 _0/10 _0/12 _0/6

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _* _* _*

Ectromelia virus 3ヶ月毎 ■ _* _* _* _* _*

Murine norovirus 12ヶ月毎 ▲ _* _* _* _* _*

Minute virus of mice 12ヶ月毎 ■ _* _* _* _* _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* Pinworm 毎月 ● _0/5 _0/3 _0/10 _0/12 _0/3 Intestinal protozoa 毎月 ● _0/5 _0/3 _0/10 _0/12 _0/3 Ectoparasites 毎月 _● _0/5 _0/3 _0/10 _0/12 _0/3 Pneumocystis murina 6ヶ月毎 ▲ －－ _* _* _* Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* Note: KSN/Slcは、血清反応のみ囮のBALB/cSlc-nu/+ または-+/+ を用いております。 判定：異常なし

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , * :Not tested , －:対象外

系統名 SPFマウス

BALB/cSlc-nu 生産コロニー

検査日週齢

(7)

Slc:Wistar/ST Slc:WsRC-Ws Slc:Zucker-fa

引佐春野引佐春野大原大原大原

I51 H21 I52 H21 O6 O6 O38

4/5 , 4/19 4/1 , 4/16 4/7 , 4/21 4/8 , 4/23 4/9 ,4/26 4/1 4/7 検査項目 6w , Re 6w , Re 6w , Re 6w , Re 6w , Re Re Re Pseudomonas aeruginosa 毎月 ○ _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5 Salmonella spp. 毎月 ○ _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5 Salmonella typhimurium 毎月 □ _0/20 _0/20 _0/20 _0/20 _0/20 _0/5 _0/5 Pasteurella pneumotropica 毎月 ○ _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5 Bordetella bronchiseptica 毎月 ○ _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5 Streptococcus pneumoniae 毎月 ○ _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5 Corynebacterium kutscheri 毎月 ○ _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5 毎月 □ _0/20 _0/20 _0/20 _0/20 _0/20 _0/5 _0/5 Clostridium piliforme 毎月 ■ _0/20 _0/20 _0/20 _0/20 _0/20 _0/5 _0/5 CAR bacillus 12ヶ月毎 ■ _* _0/10 _* _0/10 _0/10 _0/5 _* Helicobacter hepaticus 6ヶ月毎 ▲ _* _* _* _* _* _* _* Helicobacter bilis 6ヶ月毎 ▲ _* _* _* _* _* _* _* Mycoplasma pulmonis 毎月 ○ 0/40 0/20 0/40 0/20 0/40 0/5 0/5 毎月 ■ _0/20 _0/20 _0/20 _0/20 _0/20 _0/5 _0/5 Sialodacryoadenitis virus 毎月 ■ _0/20 _0/20 _0/20 _0/20 _0/20 _0/5 _0/5 Sendai virus 毎月 ■ _0/20 _0/20 _0/20 _0/20 _0/20 _0/5 _0/5 Hantavirus 3ヶ月毎 ■ _0/10 _0/10 _0/10 _0/10 _0/10 _0/5 _0/5

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _* _* _* _* _*

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _* _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* _* _*

Toolan's H-1 virus 12ヶ月毎 ■ _* _* _* _* _* _* _*

Kilham rat virus 12ヶ月毎 ■ _* _* _* _* _* _* _*

Pinworm 毎月 ● _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5

Intestinal protozoa 毎月 ● _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5

Ectoparasites 毎月 ● _0/40 _0/20 _0/40 _0/20 _0/40 _0/5 _0/5

Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _*

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested 系統名生産コロニー検査日週齢 Slc:SD Slc:Wistar SPFラット

(8)

Hos:Donryu ACI/NSlc BN/SsNSlc DA/Slc DIS/EisSlc DIR/EisSlc EHBR/EisSlc F344/NSlc GK/Slc

大原引佐大原大原引佐引佐引佐引佐引佐

O38 I36 O38 O38 I26 I26 I36 I36 I56

4/15 4/5 4/15 4/22 4/9 4/9 4/5 4/19 4/14 検査項目 6w Re Re Re Re Re Re 6w , Re Re Pseudomonas aeruginosa 毎月 ○ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Salmonella spp. 毎月 ○ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Salmonella typhimurium 毎月 □ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Pasteurella pneumotropica 毎月 ○ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Bordetella bronchiseptica 毎月 ○ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Streptococcus pneumoniae 毎月 ○ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Corynebacterium kutscheri 毎月 ○ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 毎月 □ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Clostridium piliforme 毎月 ■ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _* Helicobacter hepaticus 6ヶ月毎 ▲ _* _* _* _* _* _* _* _* _* Helicobacter bilis 6ヶ月毎 ▲ _* _* _* _* _* _* _* _* _* Mycoplasma pulmonis 毎月 ○ 0/5 0/3 0/5 0/5 0/3 0/3 0/3 0/5 0/3 毎月 ■ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Sialodacryoadenitis virus 毎月 ■ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Sendai virus 毎月 ■ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Hantavirus 3ヶ月毎 ■ _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3

Toolan's H-1 virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Kilham rat virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Pinworm 毎月 ● _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Intestinal protozoa 毎月 ● _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Ectoparasites 毎月 ● _0/5 _0/3 _0/5 _0/5 _0/3 _0/3 _0/3 _0/5 _0/3 Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* _* _* Note: 判定：異常なし生産コロニー検査日週齢

(9)

HWY/Slc KDP/Slc LEW/SsNSlc SHR/Izm SHR/NDmcr-cp SHRSP/Izm SHRSP5/Dmcr WKY/Izm WBN/KobSlc

引佐引佐引佐引佐引佐引佐引佐引佐大原

I56 I56 I36 I26 I26 I26 I26 I26 O38

4/14 4/28 4/13 , 4/26 4/2 4/2 4/26 4/16 4/9 / 検査項目 Re Re Re 6w , Re Re 7w , Re 6w , Re 6w , Re Pseudomonas aeruginosa 毎月 ○ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Salmonella spp. 毎月 ○ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Salmonella typhimurium 毎月 □ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Pasteurella pneumotropica 毎月 ○ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Bordetella bronchiseptica 毎月 ○ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Streptococcus pneumoniae 毎月 ○ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Corynebacterium kutscheri 毎月 ○ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* 毎月 □ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Clostridium piliforme 毎月 ■ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _* Helicobacter hepaticus 6ヶ月毎 ▲ _* _* _* _* _* _* _* _* _* Helicobacter bilis 6ヶ月毎 ▲ _* _* _* _* _* _* _* _* _* Mycoplasma pulmonis 毎月 ○ 0/3 0/3 0/10 0/3 0/3 0/3 0/3 0/3 * 毎月 ■ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Sialodacryoadenitis virus 毎月 ■ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Sendai virus 毎月 ■ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Hantavirus 3ヶ月毎 ■ _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _*

Toolan's H-1 virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Kilham rat virus 12ヶ月毎 ■ _* _* _* _* _* _* _* _* _*

Pinworm 毎月 ● _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Intestinal protozoa 毎月 ● _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Ectoparasites 毎月 ● _0/3 _0/3 _0/10 _0/3 _0/3 _0/3 _0/3 _0/3 _* Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* _* _* _* _* * 0/3 0/3 0/3 * * * * 0/3 0/3 * 0/3

0/3 0/3 0/3 0/3 0/3 * 0/3 0/3 0/3 0/3 * * Re 0/3 0/3 * 週齢系統名 WKAH/HkmSlc 生産コロニー検査日引佐 I56 4/6 SPFラット

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F344/NSlc-Tg (gpt delta) SD-Tg(CAG-EGFP) 大原大原 O2 O2 4/2 4/12 検査項目 4w , Re 4w , Re Pseudomonas aeruginosa 毎月 ○ _0/3 _0/5 Salmonella spp. 毎月 ○ _0/3 _0/5 Salmonella typhimurium 毎月 □ _0/3 _0/5 Pasteurella pneumotropica 毎月 ○ _0/3 _0/5 Bordetella bronchiseptica 毎月 ○ _0/3 _0/5 Streptococcus pneumoniae 毎月 ○ _0/3 _0/5 Corynebacterium kutscheri 毎月 ○ _0/3 _0/5 毎月 □ _0/3 _0/5 Clostridium piliforme 毎月 ■ _0/3 _0/5 CAR bacillus 12ヶ月毎 ■ _0/3 _0/5 Helicobacter hepaticus 6ヶ月毎 ▲ _* _* Helicobacter bilis 6ヶ月毎 ▲ _* _* Mycoplasma pulmonis 毎月 ○ 0/3 0/5 毎月 ■ _0/3 _0/5 Sialodacryoadenitis virus 毎月 ■ _0/3 _0/5 Sendai virus 毎月 ■ _0/3 _0/5 Hantavirus 3ヶ月毎 ■ _0/3 _0/5

Pneumonia virus of mice 12ヶ月毎 ■ _* _*

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _*

Reovirus type 3 12ヶ月毎 ■ _* _*

Toolan's H-1 virus 12ヶ月毎 ■ _* _*

Kilham rat virus 12ヶ月毎 ■ _* _*

Pinworm 毎月 ● _0/3 _0/5

Intestinal protozoa 毎月 ● _0/3 _0/5

Ectoparasites 毎月 ● _0/3 _0/5

Dermatophytes 6ヶ月毎 ○ _* _*

Note: 判定：異常なし

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested 週齢

生産コロニー系統名

検査日

(11)

SPFスナネズミ Slc:Syrian J2N-k MON/Jms/GbsSlc 大原大原引佐 O7 O7 I31 4/8 , 4/20 4/13 4/23 検査項目 10w , 8w , Re Re 検査項目 Re

Pseudomonas aeruginosa 毎月 ○ _0/10 _0/3 _{Pseudomonas aeruginosa} 毎月 ○ _0/5

Salmonella spp. 毎月 ○ _0/10 _0/3 _{Salmonella spp.} 毎月 ○ _0/5

Salmonella typhimurium 毎月 □ _0/10 _0/3 _{Salmonella typhimurium} 毎月 □ _0/5

Pasteurella pneumotropica 毎月 ○ _0/10 _0/3 _{Pasteurella pneumotropica} 毎月 ○ _0/5

Bordetella bronchiseptica 毎月 ○ _0/10 _0/3 _{Bordetella bronchiseptica} 毎月 ○ _0/5

Streptococcus pneumoniae 毎月 ○ _0/10 _0/3 _{Corynebacterium kutscheri} 毎月 ○ _0/5

Corynebacterium kutscheri 毎月 ○ _0/10 _0/3 毎月 □ _0/5

毎月 □ _0/10 _0/3 _{Clostridium piliforme} 毎月 ■ _0/5

Yersinia pseudotuberculosis 3ヶ月毎 ○ _0/10 _0/3 _{Helicobacter hepaticus} 6ヶ月毎 ▲ _*

Clostridium piliforme 毎月 ■ _0/10 _0/3 _{Helicobacter bilis} 6ヶ月毎 ▲ _*

Mycoplasma pulmonis 毎月 ○ _0/10 _0/3 _{Mycoplasma pulmonis} 毎月 ○ _0/5

毎月 ■ _0/10 _0/3 毎月 ■ _0/5

Sendai virus 毎月 ■ 0/10 0/3 Sendai virus 毎月 ■ 0/5

Hantavirus 3ヶ月毎 ■ _0/10 _0/3 _Pinworm 毎月 ● _0/5

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _{Intestinal protozoa} 毎月 ● _0/5

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/10 _0/3 _{Ectoparasites} 毎月 ● _0/5

Eimeria caviae 毎月 ● _0/10 _0/3 ○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) ,

Pinworm 毎月 ● _0/10 _0/3 ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , Re:退役動物 , * :Not tested

検査日週齢系統名生産コロニー検査日週齢系統名生産コロニー SPFハムスター

(12)

中伊豆中伊豆中伊豆中伊豆中伊豆

N12 N14 N43 N44 N43

4/8 , 4/27 4/6 , 4/20 4/8 , 4/27 4/6 , 4/20 4/1 , 4/16

検査項目 4w , Re 4w , Re 検査項目 10w , Re 10w , Re 10w , Re

Pseudomonas aeruginosa 毎月 ○ _0/20 _0/20 _{Salmonella spp.} 毎月 ○ _0/5 _0/5 _0/5

Salmonella spp. 毎月 ○ _0/20 _0/20 _{Salmonella typhimurium} 毎月 □ _0/5 _0/5 _0/5

Salmonella typhimurium 毎月 □ _0/20 _0/20 _{Pasteurella multocida} 毎月 ○ _0/5 _0/5 _0/5

Pasteurella pneumotropica 毎月 ○ _0/20 _0/20 _{Bordetella bronchiseptica} 毎月 ○ _0/5 _0/5 _0/5

Bordetella bronchiseptica 毎月 ○ _0/20 _0/20 毎月 □ _0/5 _0/5 _0/5

毎月 □ _0/20 _0/20 _{Clostridium piliforme} 毎月 ■ _0/5 _0/5 _0/5

Streptococcus zooepidemicus 毎月 ○ _0/20 _0/20 _{Mycoplasma pulmonis} 毎月 ○ _0/5 _0/5 _0/5

Streptococcus pneumoniae 毎月 ○ _0/20 _0/20 毎月 ■ _0/5 _0/5 _0/5

Yersinia pseudotuberculosis 3ヶ月毎 ○ _0/20 _0/20 _{Sendai virus} 毎月 ■ _0/5 _0/5 _0/5

Clostridium piliforme 毎月 ■ _0/20 _0/20 _{Eimeria spp.} 毎月 ● _0/5 _0/5 _0/5

Mycoplasma pulmonis 毎月 ○ _0/20 _0/20 _{Psoroptes cuniculi} 毎月 ● _0/5 _0/5 _0/5

毎月 ■ _0/20 _0/20 ○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) ,

Sendai virus 毎月 ■ 0/20 0/20 Re:退役動物

Eimeria caviae 毎月 ● _0/20 _0/20

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , Re:退役動物 , * :Not tested

Note: 判定：異常なし検査日検査日 0/5 0/5 0/5 0/5 0/5 0/5 0/5 0/5 10w , Re 4/13 , 4/28 週齢週齢 0/5 0/5 0/5 生産コロニー生産コロニー中伊豆 N44 系統名 SPFモルモット系統名 Slc:Hartley SPFウサギ Slc:NZW Slc:JW/CSK

(13)

Hos:HR-1 Hos:HR-1 SHR/Hos WKY/Hos Hos:OLETF Hos:LETO

星野試験動物飼育所星野試験動物飼育所星野試験動物飼育所星野試験動物飼育所星野試験動物飼育所星野試験動物飼育所

B棟 C棟 C棟 C棟 C棟 C棟

4/7 4/14 4/14 4/14 4/14 4/14

検査項目 Re Re 検査項目 Re Re Re Re

Pseudomonas aeruginosa 毎月 ○ _0/4 _0/4 _{Pseudomonas aeruginosa} 毎月 ○ _0/3 _0/2 _0/3 _0/2

Citrobacter rodentium 毎月 ○ _0/4 _0/4 _{Salmonella spp.} 毎月 ○ _0/3 _0/2 _0/3 _0/2

Salmonella spp. 毎月 ○ _0/4 _0/4 _{Salmonella typhimurium} 毎月 □ _0/3 _0/2 _0/3 _0/2

Salmonella typhimurium 毎月 □ _0/4 _0/4 _{Pasteurella pneumotropica} 毎月 ○ _0/3 _0/2 _0/3 _0/2

Pasteurella pneumotropica 毎月 ○ _0/4 _0/4 _{Bordetella bronchiseptica} 毎月 ○ _0/3 _0/2 _0/3 _0/2

Corynebacterium kutscheri 毎月 ○ _0/4 _0/4 _{Streptococcus pneumoniae} 毎月 ○ _0/3 _0/2 _0/3 _0/2

毎月 □ _0/4 _0/4 _{Corynebacterium kutscheri} 毎月 ○ _0/3 _0/2 _0/3 _0/2

Clostridium piliforme 毎月 ■ _0/4 _0/4 毎月 □ _0/3 _0/2 _0/3 _0/2

CAR bacillus 12ヶ月毎 ■ _* _* _{Clostridium piliforme} 毎月 ■ _0/3 _0/2 _0/3 _0/2

Helicobacter hepaticus 3ヶ月毎 ▲ _0/4 _0/4 _{CAR bacillus} 12ヶ月毎 ■ _0/3 _0/2 _0/3 _0/2

Helicobacter bilis 3ヶ月毎 ▲ _0/4 _0/4 _{Helicobacter hepaticus} 6ヶ月毎 ▲ _* _* _* _*

Mycoplasma pulmonis 毎月 ○ _0/4 _0/4 _{Helicobacter bilis} 6ヶ月毎 ▲ _* _* _* _*

毎月 ■ 0/4 0/4 Mycoplasma pulmonis 毎月 ○ 0/3 0/2 0/3 0/2

Mouse hepatitis virus 毎月 ■ _0/4 _0/4 毎月 ■ _0/3 _0/2 _0/3 _0/2

Sendai virus 毎月 ■ _0/4 _0/4 _{Sialodacryoadenitis virus} 毎月 ■ _0/3 _0/2 _0/3 _0/2

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _{Sendai virus} 毎月 ■ _0/3 _0/2 _0/3 _0/2

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/4 _0/4 _Hantavirus 3ヶ月毎 ■ _0/3 _0/2 _0/3 _0/2

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _{Pneumonia virus of mice} 12ヶ月毎 ■ _* _* _* _*

Ectromelia virus 3ヶ月毎 ■ _* _* _{Mouse adenovirus 1 (FL)} 3ヶ月毎 ■ _* _* _* _*

Murine norovirus 12ヶ月毎 ▲ _* _* Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _*

Minute virus of mice 12ヶ月毎 ■ _* _* _{Reovirus type 3} 12ヶ月毎 ■ _* _* _* _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _{Toolan's H-1 virus} 12ヶ月毎 ■ _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _{Kilham rat virus} 12ヶ月毎 ■ _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _Pinworm 毎月 ● _0/3 _0/2 _0/3 _0/2

Pinworm 毎月 ● _0/4 _0/4 _{Intestinal protozoa} 毎月 ● _0/3 _0/2 _0/3 _0/2

Intestinal protozoa 毎月 ● _0/4 _0/4 _{Ectoparasites} 毎月 ● _0/3 _0/2 _0/3 _0/2

Ectoparasites 毎月 ● _0/4 _0/4 _{Dermatophytes} 6ヶ月毎 ○ _* _* _* _* Dermatophytes 6ヶ月毎 ○ _* _* 生産コロニー検査日系統名系統名 SPFマウス SPFラット

週齢生産コロニー

検査日週齢

(14)

C57BLKS/JIar-m +/+Leprdb C57BLKS/JIar-+Leprdb_/+Leprdb Iar:IVCS TSOD TSNO 動物繁殖研究所動物繁殖研究所動物繁殖研究所動物繁殖研究所動物繁殖研究所 200-4 200-5 200-3 200-4 200-5 4/13 4/27 4/13 4/20 4/20 検査項目 9w 9w 10w 9w 9w Pseudomonas aeruginosa 毎月 ○ _0/5 _0/5 _0/3 _0/5 _0/3 Citrobacter rodentium 毎月 ○ _0/5 _0/5 _0/3 _0/5 _0/3 Salmonella spp. 毎月 ○ _0/5 _0/5 _0/3 _0/5 _0/3 Salmonella typhimurium 毎月 □ _0/5 _0/5 _0/3 _0/5 _0/3 Pasteurella pneumotropica 毎月 ○ _0/5 _0/5 _0/3 _0/5 _0/3 Corynebacterium kutscheri 毎月 ○ _0/5 _0/5 _0/3 _0/5 _0/3 毎月 □ _0/5 _0/5 _0/3 _0/5 _0/3 Clostridium piliforme 毎月 ■ _0/5 _0/5 _0/3 _0/5 _0/3 CAR bacillus 12ヶ月毎 ■ _* _* _* _* _* Helicobacter hepaticus 3ヶ月毎 ▲ _0/5 _0/5 _0/3 _0/5 _0/3 Helicobacter bilis 3ヶ月毎 ▲ _0/5 _0/5 _0/3 _0/5 _0/3 Mycoplasma pulmonis 毎月 ○ _0/5 _0/5 _0/3 _0/5 _0/3 毎月 ■ 0/5 0/5 0/3 0/5 0/3

Mouse hepatitis virus 毎月 ■ _0/5 _0/5 _0/3 _0/5 _0/3

Sendai virus 毎月 ■ _0/5 _0/5 _0/3 _0/5 _0/3

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _* _* _*

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/5 _0/5 _0/3 _0/5 _0/3

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _* _* _*

Ectromelia virus 3ヶ月毎 ■ _* _* _* _* _*

Murine norovirus 12ヶ月毎 ▲ _* _* _* _* _*

Minute virus of mice 12ヶ月毎 ■ _* _* _* _* _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _* _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _* _* _*

Reovirus type 3 12ヶ月毎 ■ _* _* _* _* _* Pinworm 毎月 ● _0/5 _0/5 _0/3 _0/5 _0/3 Intestinal protozoa 毎月 ● _0/5 _0/5 _0/3 _0/5 _0/3 Ectoparasites 毎月 ● _0/5 _0/5 _0/3 _0/5 _0/3 Dermatophytes 6ヶ月毎 ○ _* _* _* _* _* Note: 判定：異常なし SPFマウス生産コロニー検査日週齢系統名

(15)

Iar:Long-Evans Iar:Wistar-Imamichi 動物繁殖研究所動物繁殖研究所 103 103 4/6 , 4/20 4/13 , 4/27 検査項目 6w , Re 6w , Re Pseudomonas aeruginosa 毎月 ○ _0/20 _0/20 Salmonella spp. 毎月 ○ _0/20 _0/20 Salmonella typhimurium 毎月 □ _0/20 _0/20 Pasteurella pneumotropica 毎月 ○ _0/20 _0/20 Bordetella bronchiseptica 毎月 ○ _0/20 _0/20 Streptococcus pneumoniae 毎月 ○ _0/20 _0/20 Corynebacterium kutscheri 毎月 ○ _0/20 _0/20 毎月 □ _0/20 _0/20 Clostridium piliforme 毎月 ■ _0/20 _0/20 CAR bacillus 12ヶ月毎 ■ _* _* Helicobacter hepaticus 6ヶ月毎 ▲ _* _* Helicobacter bilis 6ヶ月毎 ▲ _* _* Mycoplasma pulmonis 毎月 ○ 0/20 0/20 毎月 ■ _0/20 _0/20 Sialodacryoadenitis virus 毎月 ■ _0/20 _0/20 Sendai virus 毎月 ■ _0/20 _0/20 Hantavirus 3ヶ月毎 ■ _0/10 _0/10

Pneumonia virus of mice 12ヶ月毎 ■ _* _*

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _*

Reovirus type 3 12ヶ月毎 ■ _* _*

Toolan's H-1 virus 12ヶ月毎 ■ _* _*

Kilham rat virus 12ヶ月毎 ■ _* _*

Pinworm 毎月 ● _0/20 _0/20

系統名

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested 生産コロニー

検査日週齢

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SPFラット

CBA/CaOlaHsd C.B-17/IcrHsd-Prkdcscid RccHan®:WIST

春野春野引佐

H32 H35 I56

4/8 4/6 4/21

検査項目 6w , Re 9w , 15w 検査項目 3w , Re

Pseudomonas aeruginosa 毎月 ○ _0/5 _0/4 _{Pseudomonas aeruginosa} 毎月 ○ _0/10

Citrobacter rodentium 毎月 ○ _0/5 _0/4 _{Salmonella spp.} 毎月 ○ _0/10

Salmonella spp. 毎月 ○ _0/5 _0/4 _{Salmonella typhimurium} 毎月 □ _0/10

Salmonella typhimurium 毎月 □ _0/5 _0/8 _{Pasteurella pneumotropica} 毎月 ○ _0/10

Pasteurella pneumotropica 毎月 _○ _0/5 _0/4 _{Bordetella bronchiseptica} 毎月 _○ _0/10

Staphylococcus aureus 毎月 ○ － _0/4 _{Streptococcus pneumoniae} 毎月 ○ _0/10

Corynebacterium kutscheri 毎月 _○ _0/5 _0/4 _{Corynebacterium kutscheri} 毎月 _○ _0/10

毎月 □ _0/5 _0/8 毎月 □ _0/10

Clostridium piliforme 毎月 ■ _0/5 _0/8 _{Clostridium piliforme} 毎月 ■ _0/10

CAR bacillus 12ヶ月毎 ■ _* _* _{CAR bacillus} 12ヶ月毎 ■ _*

Helicobacter hepaticus 3ヶ月毎 ▲ _* _0/4 _{Helicobacter hepaticus} 6ヶ月毎 ▲ _*

Helicobacter bilis 3ヶ月毎 ▲ _* _0/4 _{Helicobacter bilis} 6ヶ月毎 ▲ _*

Mycoplasma pulmonis 毎月 ○ _0/5 _0/4 _{Mycoplasma pulmonis} 毎月 ○ _0/10

毎月 _■ _0/5 _0/8 毎月 _■ _0/10

Mouse hepatitis virus 毎月 ■ _0/5 _0/8 _{Sialodacryoadenitis virus} 毎月 ■ _0/10

Sendai virus 毎月 ■ 0/5 0/8 Sendai virus 毎月 ■ 0/10

Pneumonia virus of mice 12ヶ月毎 ■ _* _* _Hantavirus 3ヶ月毎 ■ _0/5

Lymphocytic choriomeningitis virus 3ヶ月毎 ■ _0/5 _0/8 _{Pneumonia virus of mice} 12ヶ月毎 ■ _*

Mouse adenovirus 1 (FL) 3ヶ月毎 ■ _* _* _{Mouse adenovirus 1 (FL)} 3ヶ月毎 ■ _*

Ectromelia virus 3ヶ月毎 ■ _* _* _{Theiler's murine encephalomyelitis virus}12ヶ月毎 ■ _*

Murine norovirus 12ヶ月毎 ▲ _* _* _{Reovirus type 3} 12ヶ月毎 ■ _*

Minute virus of mice 12ヶ月毎 ■ _* _* _{Toolan's H-1 virus} 12ヶ月毎 ■ _*

Epizootic diarrhea of infant mice virus 12ヶ月毎 ■ _* _* _{Kilham rat virus} 12ヶ月毎 ■ _*

Theiler's murine encephalomyelitis virus 12ヶ月毎 ■ _* _* _Pinworm 毎月 ● _0/10

Reovirus type 3 12ヶ月毎 ■ _* _* _{Intestinal protozoa} 毎月 ● _0/10

Pinworm 毎月 ● _0/5 _0/4 _{Ectoparasites} 毎月 ● _0/10

Intestinal protozoa 毎月 ● _0/5 _0/4 _{Dermatophytes} 6ヶ月毎 ○ _*

Ectoparasites 毎月 _● _0/5 _0/4

Pneumocystis murina 6ヶ月毎 ▲ － _*

Note:C.B-17/IcrHsd-Prkdcscidは、血清反応のみ囮のBALB/cSlc-nu /+または-+/+ を用いております。 判定：異常なし

系統名系統名

○:培養検査 , ●:寄生虫検査 , □:血清反応(Aggl.) , ■:血清反応(ELISA or IFA) , ▲:PCR , Re:退役動物 , * :Not tested , －:対象外検査日週齢生産コロニー週齢検査日 SPFマウス生産コロニー

系統名生産コロニー 引佐引佐 SPFマウス大原引佐春野引佐春野引佐春野 Slc:ddY I28 Slc:ICR I57 A/JJmsSlc O35 AKITA/Slc I22 AKR/NSlc H34 BALB/cCrSlc I34 H34 I24 H24 検査日 4/14, 4/29 4/6, 4

系統名生産コロニー引佐引佐 SPFマウス大原引佐春野引佐春野引佐春野 Slc:ddY I28 Slc:ICR I57 A/JJmsSlc O35 AKITA/Slc I22 AKR/NSlc H34 BALB/cCrSlc I34 H34 I24 H24 検査日 4/14, 4/29 4/6, 4