• 検索結果がありません。

構造生物学研究室 Structural Biology

N/A
N/A
Protected

Academic year: 2021

シェア "構造生物学研究室 Structural Biology"

Copied!
1
0
0

読み込み中.... (全文を見る)

全文

(1)

構造生物学研究室

Structural Biology

教 授 水口 峰之 Mineyuki Mizuguchi 准教授 帯田 孝之 Takayuki Obita 講 師(前)篠田 裕之 Hiroyuki Shinoda

◆ 原 著

1) Umetsu Y., Aizawa T., Muto K., Yamamoto H., Kamiya M., Kumaki Y., Mizuguchi M., Demura M., Hayakawa Y., and Kawano K. : The C-terminal elongation of growth-blocking peptide enhances its biological activity and membrane binding affinity. J.

Biol. Chem., 284: 29625-29634, 2009.

2) Takahashi M., Mizuguchi M., Shinoda H., Aizawa T., Demura M., Okazawa H., and Kawano K. : Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain. Biochim. Biophys. Acta - Proteins and Proteomics, 1804: 1500-1507, 2010.

3) Miyata M., Sato T., Mizuguchi M., Nakamura T., Ikemizu S., Nabeshima Y., Susuki S., Suwa Y., Morioka H., Ando Y., Suico M.

A., Shuto T., Koga T., Yamagata Y., and Kai H. : Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding. Biochemistry, 49: 114-123, 2010.

4) Kamiya M., Oyauchi K., Sato Y., Yokoyama T., Wang M., Aizawa T., Kumaki Y., Mizuguchi M., Imai K., Demura M., Suzuki K., and Kawano K. : Structure-activity relationship of a novel pentapeptide with cancer cell growth-inhibitory activity. J. Pept.

Sci., 16: 242-248, 2010.

5) Iwai M., Yoshida H., Obara M., Horimoto E., Nakamura K., Takizawa T., Kurata T., Mizuguchi M., Daikoku T., and Shiraki K. : Widespread circulation of echovirus type 13 demonstrated by increased seroprevalence in Toyama, Japan between 2000 and 2003. Clin. Vaccine Immunol., 17: 764-770, 2010.

◆ 総 説

1) 水口峰之,岡澤 均:天然変性タンパク質PQBP-1の揺らぎと生体機能.メディカルバイオ10月号別冊 揺らぎと 生体機能,44-48,2010.

◆ 学会報告

1) Yokoyama T., Nabeshima Y., Hosoya T., Ohara T., Kurihara K., Kusaka K., Mizuguchi M., Tanaka I., and Niimura N. : Preliminary neutron crystallographic study and X-ray structural analysis of mutant transthyretin. 日本生物物理学会,2010, 9, 20-22,仙台.

2) Kodera N., Mori T., Mizuno S., Mizuguchi M., Aizawa S., Ando T. : Direct visualization of intrinsically disordered proteins PQBP-1 and FliK using high-speed force microscopy. 日本生物物理学会,2010, 9, 20-22,仙台.

3) 小島理恵子,帯田孝之,Samson R. Y., Bell S. D., Williams R. L., 水口峰之:新規ESCRT関連タンパク質CdvAの構造 基盤研究.第32回生体膜と薬物の相互作用シンポジウム,2010, 11, 29-30,富山.

4) 櫛引崇弘,神谷昌克,相沢智康,熊木康裕,菊川峰志,水口峰之,出村 誠,川畑俊一郎,河野敬一:抗菌ペプチ TPとリポ多糖の相互作用解析.第32回生体膜と薬物の相互作用シンポジウム,2010, 11, 29-30,富山.

5) 小島理恵子,帯田孝之,Samson R. Y., Bell S. D., Williams R. L., 水口峰之:細胞分裂を担う新たな古細菌ESCRTタン パク質CdvAの構造的基盤研究.第33回日本分子生物学会 第83回日本生化学会大会 合同大会,2010, 12, 7-10,

神戸.

◆ その他

1) 水口峰之:トランスサイレチンの立体構造変化とアミロイド病.水和ナノ構造研究会.2010, 9, 6,静岡県賀茂郡.

2) Obita T. : Structural Studies of the interaction between Vps4 and ESCRT-III.Kobe University Global COE Program on Integrative Membrane Biology 4th Workshop, 2010, 7, 15-16, Awaji. (Invited lecture)

参照

関連したドキュメント

Calcula- tion result of RMSD, B-factor and binding free energy suggests that wild type HA has much structural stabil- ity, which contributes to binding affinity with Fab frag-

Northern blot analysis using 5’ portion of the chicken DDB1 cDNA as a probe detected a single transcript of ~ 4.3 kb in chicken DT40 cells as well as in human HeLa cells

The present results also provide in situ hybridization evidence that at least chief cells and possibly both chief cells and sustentacular cells of the carotid body express NGF mRNA..

To this aim, we propose to use categories of fractions of a fundamental category with respect to suitably chosen sytems of morphisms and to investigate quotient categories of those

Standard domino tableaux have already been considered by many authors [33], [6], [34], [8], [1], but, to the best of our knowledge, the expression of the

The edges terminating in a correspond to the generators, i.e., the south-west cor- ners of the respective Ferrers diagram, whereas the edges originating in a correspond to the

The reactions chosen to represent the extrinsic coagulation pathway, the generation of phospholipid binding sites due to platelet activation, the influence of thrombin on Factor

We recall here the de®nition of some basic elements of the (punctured) mapping class group, the Dehn twists, the semitwists and the braid twists, which play an important.. role in