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Study on the Effects of Cognitive Behavioral Therapy for Patients with Schizophrenia

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―  19  ―

Study on the Effects of Cognitive Behavioral Therapy for Patients with Schizophrenia

Kei M

ATSUSHIMA

, Koji O

GOMORI

, Kentaro T

ANAKA

, Rika Y

ANO

, Keiichiro T

AKATA

 and Ryoji N

ISHIMURA

Department of Psychiatry, Faculty of Medicine, Fukuoka University

Abstract:Many studies have previously addressed cognitive behavioral therapy(CBT)for pa- tients with schizophrenia in foreign countries, but there have so far been few studies on the ef- fects of CBT for schizophrenia in Japan. This study was conducted to verify the effects of CBT  on  patients  with  schizophrenia  in  Japan. Twelve  patients  with  schizophrenia  were  selected  as  subjects. The subjects were divided into 2 groups of 6 patients. One group had therapeutic in- tervention  of  CBT(CBT  group),  and  another  group  had  treatmentasusual(control  group) 

for 5 weeks. The following 10 assessments were used for the evaluation. 1)Positive and Nega- tive Symptom Scale(PANSS), 2)Schedule for Assessment of Insight(SAI), 3)the Calgary De- pression  Scale  for  Schizophrenia(CDSS), 4)Event  Related  Potential  P300, 5)Wisconsin  Card  Sorting Test, 6)subtests concerned with attention and concentrations in the Wechsler Memory  ScaleRevised, 7)Word  Fluency  Test, 8)Trail  Making  Test, 9)Stroop  Test,  and 10)WHO  QOL26. These assessments were conducted before and after intervention and the changes before  and after intervention in assessments were compared between the 2 groups. No significant dif- ference was detected between the groups with respect to any background index. No significant  difference  was  detected  between  the  groups  with  respect  to  any  assessment  before  the  intervention. The  betweengroup  comparison  of  change  after  intervention  in  each  assessment  showed  some  significant  differences. The  CBT  group  showed  a  significant  decrease  in  the  subscale of PANSS score in comparison to the control group. The CBT group showed a signifi- cant increase in scores in the insight into mental symptoms, a subscale of SAI, and the total SAI,  in comparison to the control group. The CBT group showed a significant decrease in the CDSS  score in comparison to the control group. The CBT group showed a significant increase in the  average  score  of  QOL  in  the  physical  aspect  subtest  in  comparison  to  the  control  group. CBT  was suggested to improve symptoms, insight into disease, depression and QOL in patients with  schizophrenia.

Key  words:Cognitive  behavioral  therapy,  Schizophrenia,  Psychoeducation,  Social  skills  training, Neurocognitive function, Psychological test

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