Evaluation of the oxygen demand of the high-intensity exercise using hypoxia and hyperoxia gas.

᣽↝ᚸ̖‒

Evaluation of the oxygen demand of the high-intensity exercise using hypoxia and hyperoxia gas.

ఀ⸨ ᬛᘧ Tomonori Ito

㸦ឡ▱ᏛἨ▷ᮇ኱Ꮫᗂඣᩍ⫱Ꮫ⛉㸧

ᢒ 㘓

㐠ື᫬ࡢ㓟⣲㟂せ㔞࡜㓟⣲ᦤྲྀ㔞ࡢᕪศ࠿ࡽồࡵࡓ㓟⣲೉ࡣ↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡢฟຊࢆ♧ࡍࡶࡢ

࡛࠶ࡾࠊࡇࡢ᭱኱್ࡣ↓㓟⣲ᛶ⬟ຊࡢᣦᶆ࡜࡞ࡿࠋᮏ◊✲ࡣ␗࡞ࡿ㓟⣲⃰ᗘ⎔ቃୗ࡟࠾ࡅࡿ㐠ື୰ࡢ࢞

ࢫ஺᥮ㅖ㔞ࢆゎᯒࡋࠊ㓟⣲㟂せ㔞ࡢホ౯࡟ࡘ࠸᳨࡚ウࡋࡓࠋప㓟⣲(14.6%)ࠊ㏻ᖖ኱Ẽ(20.9%)ཬࡧ㧗㓟

⣲(38.5%)ࡢ᮲௳ୗ࡟࠾࠸࡚ࠊ

6

ศ㛫ẖࡢ

6

ẁ㝵ࢫࢸࢵࣉ㈇Ⲵ㐠ືࢆᐇ᪋ࡋࡓࠋྛ᮲௳㛫࡟࠾࠸࡚ᐃᖖ≧

ែ࡜ᛮࢃࢀࡿྛࢫࢸࢵࣉ᭱⤊

2

ศ㛫ࡢ㓟⣲ᦤྲྀ㔞࡟ᕪࡣㄆࡵࡽࢀ࡞࠿ࡗࡓࠋᚰᢿᩘ࡜᥮Ẽ㔞ࡣ྾Ẽࡢ㓟

⣲⃰ᗘࡢቑຍ࡟క࠸ࠊప࠸್࡜࡞ࡿഴྥࢆ♧ࡋࡓࠋࡋࡓࡀࡗ࡚ࠊ㓟⣲⃰ᗘࢆ㧗ࡵࡿࡇ࡜࡟ࡼࡾࠊ⏕య࡟

࡜ࡗ࡚㈇ᢸࡢᑡ࡞࠸ᐜ᫆࡞㐠ືࡀྍ⬟࡟࡞ࡿࡇ࡜ࡀ♧၀ࡉࢀࡓࠋࡲࡓࠊᐃᖖ≧ែୗࡢ㓟⣲ᦤྲྀ㔞ࢆ㓟⣲

㟂せ㔞࡜ࡋ

Power㸫V

㸬

O

2㛵ಀ࠿ࡽ㓟⣲㟂せ㔞ࡢ㏆ఝᘧࢆồࡵࡓࠋࡑࡢ⤖ᯝࠊ┤⥺ᅇᖐࡼࡾࡶ஧ḟከ㡯ᘧ ࡢ᭤⥺ᅇᖐࡢ࡯࠺ࡀ⢭ᗘࡢ㧗࠸㏆ఝ࡜࡞ࡿࡇ࡜ࡀ♧၀ࡉࢀࡓࠋຍ࠼࡚ࠊV㸬

O

2

max

ࢆ㉺࠼ࡿ㧗ᙉᗘ㐠ື᫬

ࡢ㓟⣲㟂せ㔞ࡣࡇࢀࡲ࡛ࡢᐃᖖୗ┤⥺ᅇᖐ࡟ࡼࡿ ᐃࡼࡾࡶ㧗࠸್࡛࠶ࡿ࡜ࡇ࡜ࡀ♧၀ࡉࢀࡓࠋ

࣮࣮࢟࣡ࢻ

㓟⣲㟂せ㔞 oxygen demandࠊ㧗㓟⣲ hyperoxiaࠊ᭤⥺ᅇᖐ curvilinear regression

┠ ḟ

1 ⥴ゝ 2 ᪉ἲ 3 ⤖ᯝ 4 ⪃ᐹ 5 ࡲ࡜ࡵ

1

⥴ゝ

పᙉᗘࡢ㐠ື࡟࠾࠸࡚ࡣࠊ࢚ࢿࣝࢠ࣮ฟຊ࡟ᚲ せ࡞㓟⣲㟂せ㔞2GHPDQG࡜㓟⣲ᦤྲྀ㔞9㸬

2ࡀ

➼ࡋࡃࠊᐃᖖ≧ែVWHDG\VWDWHࡀ⥔ᣢ࡛ࡁࡿࠋ ࡇࢀ࡟ࡼࡾ᭷㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡢ౪⤥ࡔࡅ࡛㐠ື

ࡀ⥅⥆࡛ࡁࡿࠋ)LJ

㧗ᙉᗘࡢ㐠ື࡟࠾࠸࡚ࡣ㓟⣲㟂せ㔞࡟ᑐࡋ࡚㓟

⣲ᦤྲྀ㔞ࡀ୙㊊ࡋ᭷㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡢ౪⤥ࡔࡅ

࡛ࡣ⿵࠼࡞࠸ࠋࡑࡇ࡛↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡀືဨ

ࡉࢀࡿࠋ

ࡇࡢ↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡣࠊ࢔ࢹࣀࢩࣥ୕ࣜࣥ

㓟$73ཬࡧࢡࣞ࢔ࢳࣥ⇥㓟3&Uࡢศゎ࡟ࡼࡗ࡚

ᚓࡽࢀࡿ㠀ங㓟ᛶᶵᵓ࡜ࠊ㓟⣲ࢆ౑ࢃࡎ࡟ࢢࣜࢥ

࣮ࢤࣥཬࡧࢢࣝࢥ࣮ࢫࡀங㓟࡟ࡲ࡛ศゎࡍࡿ㐣⛬

࡛ᚓࡽࢀࡿங㓟ᛶᶵᵓ࡟ࡼࡗ࡚౪⤥ࡉࢀࡿࠋణࡋࠊ ࡇࡢங㓟ࡢ㐣ᗘ࡞⵳✚ࡣ⑂ປࢆᣍࡁࠊ㐠ື⥅⥆ࡢ ไ㝈ᅉᏊ࡜࡞ࡿࠋ㧗ᙉᗘࡢ㐠ືࡀ㛗ࡃ⥆࠿࡞࠸ࡢ ࡣࡇࡢࡓࡵ࡛࠶ࡿࠋ

↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡣ㓟⣲ࡀ↓ࡃ࡚ࡶ࢚ࢿࣝࢠ

࣮ࢆⓎ᥹࡛ࡁࡿࡀࠊࡑࡢᐜ㔞ࢆᅇ᚟ࡉࡏࡿࡓࡵ࡟

ࡣ㓟⣲ࡀᚲせ࡜࡞ࡿ ࠋࡘࡲࡾࠊ㐠ື୰࡟୙㊊ࡋ ࡓ㓟⣲ࡢ㔞࡛࠶ࡿ㓟⣲೉(O2

deficit)ࡣ㐠ືᚋ࡟㓟

⣲ ㈇ മ

(O

2

debt)

࡜ ࡋ ࡚ ㏉ ῭ ࡍ ࡿ ࡇ ࡜ ࡟ ࡞ ࡿ ࠋ

(Fig.2) 㐠ືᚋࡢ㓟⣲ᦤྲྀ㔞ࡀᏳ㟼᫬ࡼࡾࡶ㧗࠸

≧ែࡀ⥆ࡃࡢࡣࡇࡢⅭ࡛࠶ࡾࠊ㐠ືᚋࡢ㓟⣲㈇മ 㔞ࡢ್࠿ࡽ↓㓟⣲ᛶసᴗ⬟ຊࢆホ౯ࡍࡿࡇ࡜ࡀ࡛

ࡁࡿࠋࡋ࠿ࡋ࡞ࡀࡽࠊ㓟⣲㈇മ࡜㓟⣲೉ࡣᚲࡎࡋ

ࡶ➼ࡋࡃ࡞࠸ࠋ㓟⣲㈇മࡣ㓟⣲೉㏉῭ࡢ௚࡟ࠊ௦ ㅰஹ㐍࡞࡝ࡢせᅉࡀྵࡲࢀ࡚࠾ࡾࠊ㐠ືᚋࡢ㐣๫

࡞㓟⣲ᦤྲྀ㔞࡜࡞ࡗ࡚࠸ࡿࠋࡑࡇ࡛ࠊ㐠ື୰ࡢ㓟

⣲୙㊊ࡢᣦᶆࢆ㓟⣲೉࡛ホ౯ࡍࡿ᪉ἲࡀ⏝࠸ࡽࢀ

ࡿࡼ࠺࡟࡞ࡗࡓ⁵⁾⁶⁾ࠋ

㓟⣲೉ࡣ↓㓟⣲ᛶ⬟ຊࡢᣦᶆ࡜ࡋ࡚ࠊࡲࡓ㓟⣲

ᦤྲྀ㔞ࡣ᭷㓟⣲ᛶ⬟ຊࡢᣦᶆ࡜ࡋ࡚ࠊඹ࡟㐠ື⬟

ຊ࡜ᐦ᥋࡞㛵ಀࡀ࠶ࡿࠋࡇࢀࡽࡢ᭱኱್࡛࠶ࡿ᭱

኱㓟⣲೉ࡸ᭱኱㓟⣲ᦤྲྀ㔞ࡀ㧗࠸࡜࠸࠺ࡇ࡜ࡣࠊ

࢚ࢿࣝࢠ࣮ㄽⓗ࡟ࣃࣇ࢛࣮࣐ࣥࢫ࡬┤᥋ᙳ㡪ࡍࡿࠋ

㏆ᖺࠊ㐠ື᫬ࡢ㓟⣲㟂せ㔞࡜㓟⣲ᦤྲྀ㔞ࡢᕪ࠿

ࡽ㓟⣲೉ࢆồࡵࠊࡑࡢ᭱኱್࠿ࡽ↓㓟⣲ᛶసᴗ⬟

ຊ(Anaerobic capacity)ࡀホ౯ࡉࢀࡿࡼ࠺࡟࡞ࡗ

࡚ࡁࡓ ³⁾⁵⁾ࠋࡋ࠿ࡋ࡞ࡀࡽࠊࡇࡢ᪉ἲࡢၥ㢟Ⅼࡣࠊ 㓟⣲㟂せ㔞ࢆṇ☜࡟ぢ✚ࡶࡿࡇ࡜࡟࠶ࡿࠋࡇࢀࡲ

⣲ᦤྲྀ㔞(V㸬

O

2

)࡜ࡢ㛵ಀࢆ┤⥺ᅇᖐࡋࠊᐃᖖ≧ែࢆ

㉺࠼ࡿ㧗࠸㐠ືᙉᗘࡢ㓟⣲㟂せ㔞ࢆồࡵ࡚ࡁࡓ ²⁾ࠋ

(Fig.3)

ࡑࡇ࡛ᮏ◊✲࡛ࡣࠊప㓟⣲ࠊ㧗㓟⣲ࠊ㏻ᖖ኱Ẽ

࢞ࢫ྾ධୗ࡟࠾ࡅࡿከẁ㝵ࢫࢸࢵࣉ㐠ື᫬ࡢ

V

㸬

O

2

ཬࡧ࢞ࢫ஺᥮ㅖ㔞ࢆゎᯒࡋࠊ㧗ᙉᗘ㐠ື᫬ࡢ㓟⣲

㟂せ㔞ࡢホ౯࡟ࡘ࠸᳨࡚ウࡋࡓࠋ

2

᪉ἲ

2.1

⿕㦂⪅

⿕㦂⪅ࡣ೺ᗣ࡞ᡂே⏨Ꮚ㸵ྡ࡜ࡋࠊࡑࡢ㌟యⓗ

≉ᚩࢆ

Table 1

࡟♧ࡋࡓࠋ⿕㦂⪅࡟ࡣ஦๓࡟ᮏ◊

✲ࡢ┠ⓗ࡜ ᐃෆᐜཬࡧࡑࡢ༴㝤ᛶ࡟ࡘ࠸࡚ࡢㄝ

᫂ࢆ⾜࠸ࠊᮏேࡢពᛮ࡟ࡼࡾ࠸ࡘ࡛ࡶ ᐃࢆ୰Ṇ

࡛ࡁࡿࡇ࡜ࡢ☜ㄆࢆࡋࠊᮏᐇ㦂ཧຍࡢྠពࢆᚓࡓࠋ

2.2

 ᐃ᪉ἲ

ᐇ 㦂 ࡣ 㟁 ☢ ࣈ ࣞ ࣮ ࢟ ᆺ ⮬ ㌿ ㌴ ࢚ ࣝ ࢦ ࣓ ࣮ ࢱ ࣮

&RPEL$HURELNHࢆᨵⰋࡋࠊࡑࡢࢺࣝࢡཬࡧ

ࣃ࣮࣡ࢆ࣐࢖ࢡࣟࢥࣥࣆ࣮ࣗࢱ࣮࠿ࡽ⮬ືไᚚ࡛

ࡁࡿࡼ࠺࡞⿦⨨ࢆ⏝࠸ࡓࠋ࢚ࣝࢦ࣓࣮ࢱ࣮࡛ࡢ 㐠ືࡣࠊᅇ㌿ᩘࡀኚ໬ࡋ࡚ࡶࡑࢀ࡟ᛂࡌ࡚ࢺࣝࢡ

7DEOH㸯⿕㦂⪅ࡢ㌟యⓗ≉ᚩQ

$JH \U s

+HLJKW FP s :HLJKW NJ s 㹔㹍PD[ POPLQ s

POPLQNJs 9DOXHVDUHPHDQVs6'

㹔㹍

Time

㓟⣲㟂せ㔞 㓟⣲ᦤྲྀ㔞 㓟⣲೉

㓟⣲㈇മ 㐠ື୰ࡢ

㓟⣲ᦤྲྀ㔞

)LJ㧗ᙉᗘ㐠ື᫬ࡢ㓟⣲㟂せ㔞2GHPDQG

࡜㓟⣲ᦤྲྀ㔞2XSWDNH

㹔㹍

Time

㓟⣲㟂せ㔞 㓟⣲ᦤྲྀ㔞 ᐃᖖ≧ែ VWHDG\VWDWH

㐠ື୰ࡢ㓟⣲ᦤྲྀ㔞

㻲㼕㼓㻚㻝㻚పᙉᗘ㐠ື᫬䛾㓟⣲㟂せ㔞㻔㻻_㻞㼐㼑㼙㼍㼚㼐㻕 䛸㓟⣲ᦤྲྀ㔞㻔㻻_㻞㼡㼜㼠㼍㼗㼑㻕

㹔㹍

㹎㹭㹵㹣㹰

VWHDG\VWDWH

㹔㹍2max

䠛

)LJ㐠ື᫬ࡢ㓟⣲㟂せ㔞㹍GHPDQGࡢ᥎ᐃ

࡟ไᚚࡋࡓࡀࠊࡑࢀ࡛ࡶ⿕㦂⪅࡟ࡣ࣌ࢲࣝᅇ㌿ᩘ

ࢆᖖ࡟ USP ࡟ಖࡘࡇ࡜ࢆせồࡋࡓࠋ

ᮏᐇ㦂࡟ඛ❧ࡕࠊ20Watt/min ࡢࣛࣥࣉ㈇Ⲵ㐠

ືࢆ᭱኱ດຊ࡛⾜࠸ࠊ᭱኱㓟⣲ᦤྲྀ㔞(V㸬

O

2

max)ࢆ

 ᐃࡋࡓࠋ

(Table1) ᑦࠊࡇࡢ᫬ࡢ᭱኱㐠ື᫬ࡢᙉ

ᗘ(Power)ࡣ

278.0s31.4Watt

࡛࠶ࡗࡓࠋ ᮏᐇ㦂ࡣୗグ࡟♧ࡋࡓ㸱ࡘࡢ⎔ቃ᮲௳ୗ࡟࠾࠸

࡚ᐇ᪋ࡋࡓࠋ

⎔ቃ᮲௳㸸ձప 㓟 ⣲ (Hypoxia :14.6%)

ղ㏻ᖖ኱Ẽ (Normoxia :20.9%)

ճ㧗 㓟 ⣲ (Hyperoxia:38.5%) ప㓟⣲ཬࡧ㧗㓟⣲࢞ࢫ᮲௳ࡢ ᐃࡣࠊ࢞ࢫ࣎ࣥ

࣋࠿ࡽ౪⤥ࡉࢀࡓ࢞ࢫࢆỈ୰࡟㏻ࡋຍ‵ࡋࡓࡶࡢ

ࢆࢲࢢࣛࢫࣂࢵࢡ࡟㞟ࡵࠊࡑࡇ࠿ࡽ࣐ࢫࢡ࡬⧅ࡄ ᪉ᘧ࡛⾜ࡗࡓࠋ

㓟⣲࣎ࣥ࣋Ѝຍ‵ЍࢲࢢࣛࢫࣂࢵࢡЍ࣐ࢫࢡ

ࡑࢀࡒࢀࡢ᮲௳ୗ࡟࠾࠸࡚

0Watt

࠿ࡽ㸴ศẖ࡟

30

ཪࡣ

40Watt

ࡎࡘ₞ቑࡍࡿࢫࢸࢵࣉ㈇Ⲵ㐠ືࢆ

6

ẁ㝵ᐇ᪋ࡋࡓࠋ(Fig.4) ࡇࡢ㛫ࡢ࢞ࢫ஺᥮ㅖ㔞

ࢆ࣑࢟ࢩࣥࢢࢳࣕࣥࣂ࣮ἲ࡟ࡼࡾࠊ

20

⛊㛫㝸࡛㐃

⥆ⓗ࡟ ᐃࡍࡿ࡜ඹ࡟ࠊᚰᢿᩘࢆྠ᫬࡟ ᐃࡋࡓࠋ

ྛࢫࢸࢵࣉ࡟࠾࠸࡚ᐃᖖ≧ែ࡟㐩ࡋ࡚࠸ࡿ࡜ᛮࢃ

ࢀࡿ᭱ᚋࡢ

2

ศ㛫ࡢࢹ࣮ࢱࢆゎᯒࡋࡓࠋ

3

㸬⤖ᯝ

᭱ ⤊ 㸴 ẁ 㝵 ࡢ ㈇ Ⲵ ᙉ ᗘ ࡣ

V

㸬

O

2

max

ࡢ

82.1

s

7.7%࡟┦ᙜࡍࡿ㈇Ⲵᙉᗘ࡛࠶ࡗࡓࠋ㧗㓟⣲ཬࡧ㏻

ᖖ኱Ẽୗ࡟࠾࠸࡚ࡣ

7

ྡ඲ဨࡢ⿕㦂⪅ࡀࡇࡢ

6

ẁ 㝵ࡢ㐠ືࢆ᏶஢ࡍࡿࡇ࡜ࡀ࡛ࡁࡓࡀࠊప㓟⣲ୗ࡟

࠾࠸࡚ࡣ㸱ྡࡢ⿕㦂⪅ࡀ᭱ᚋࡢ

6

ศ㛫ࡢ㐠ືࢆ㐙

⾜ࡍࡿࡇ࡜ࡀ࡛ࡁ࡞࠿ࡗࡓࠋ

ከẁ㝵ࢫࢸࢵࣉ㈇Ⲵ㐠ື୰ࡢ㓟⣲ᦤྲྀ㔞ࡢ୍౛

ࢆ

Fig.5

࡟♧ࡋࡓࠋྛࢫࢸࢵࣉ࡟࠾࠸࡚㈇Ⲵᙉᗘ

ࡢᛴ⃭࡞ቑຍ࡟ᑐࡋࠊ㓟⣲ᦤྲྀ㔞ࡣᚎࠎ࡟ቑຍࡋ

୍ᐃ್࡟཰᮰ࡋ࡚࠸ࡃࠋࡇࢀࡽࡢྛࢫࢸࢵࣉ㸴ศ 㛫ࡢ㐠ືࢆ㐙⾜࡛ࡁࡓ᭱⤊ࡢ㸰ศ㛫ࡢ㓟⣲ᦤྲྀ㔞 ࡢ್ࢆࠊᐃᖖ≧ែୗ࡟࠾ࡅࡿ㓟⣲㟂せ㔞࡜ࡋ࡚ゎ ᯒࡋࡓࠋ㧗㓟⣲ࠊ㏻ᖖ኱Ẽཬࡧప㓟⣲᮲௳ୗ࡟࠾

ࡅࡿྛࢫࢸࢵࣉࡢ㈇Ⲵ㔞࡟ᑐࡍࡿ᭱⤊

2

ศ㛫ࡢ㓟

⣲ᦤྲྀ㔞ࡢ୍౛ࢆ

Fig.6

࡟♧ࡋࡓࠋࡲࡓࠊࡇࡢ

Power㸫V

㸬

O

2㛵ಀࢆ┤⥺ᅇᖐ࡛㏆ఝࡋࡓࠋ ࡇࢀࡽࡢࢹ࣮ࢱࢆᇶ࡟ྛ᮲௳ୗ࡟࠾ࡅࡿ㓟⣲ᦤ

ྲྀ㔞ࢆࡲ࡜ࡵࡓࡶࡢࢆ

Fig.7

࡟♧ࡋࡓࠋప㓟⣲ࠊ

㏻ᖖ኱Ẽཬࡧ㧗㓟⣲࢞ࢫ྾ධୗࡢ᮲௳㛫࡟ࡘ࠸࡚

ࡣࠊ࠸ࡎࢀࡢᙉᗘ࡟࠾࠸࡚ࡶ㓟⣲ᦤྲྀ㔞ࡢ᭷ព࡞

ᕪࡣㄆࡵࡽࢀ࡞࠿ࡗࡓࠋ

㻜 㻡㻜㻜 㻝㻜㻜㻜 㻝㻡㻜㻜 㻞㻜㻜㻜 㻞㻡㻜㻜

㻜 㻠㻜 㻤㻜 㻝㻞㻜 㻝㻢㻜 㻞㻜㻜

㼂㻻㻞㻔㼙㼘㻛㼙㼕㼚㻕

㻼䡋䡓䡁䡎㻔㼣㼍㼠㼠㻕

㻴㼥㼜㼑㼞㼛㼤㼕㼍 㻺㼛㼞㼙㼛㼤㼕㼍 㻴㼥㼜㼛㼤㼕㼍

)LJ㧗㓟⣲ࠊ኱Ẽࠊప㓟⣲ࡢྛ᮲௳ୗ࡟࠾ࡅࡿ

ྛ䝇䝔䝑䝥᭱⤊䠎ศ㛫䛾㓟⣲ᦤྲྀ㔞䛸䛭䛾┤⥺ᅇᖐ䛾୍౛

Power

7LPHPLQ 3URWRFRO

㼙㼡㼘㼠㼕㻌㼟㼠㼑㼜㻌㼑㼤㼑㼞㼏㼕㼟㼑㻌 㻟㻜㼛㼞㻠㻜㻌㼣㼍㼠㼠㻌㻛㻌㻢㻌㼙㼕㼚

㻲㼕㼓㻚㻠㻚⮬㌿㌴䜶䝹䝂䝯䞊䝍䞊䛻䛚䛡䜛ᐇ㦂䛾㐠ື㈇Ⲵᵝᘧ 䠄ྛ䝇䝔䝑䝥䛷䛾᭱ᚋ䛾䠎ศ㛫䜢ᇶ♏䝕䞊䝍䛸䛧䛶ゎᯒ䛧䛯䠅

0 500 1000 1500 2000 2500

㻜 㻢 㻝㻞 㻝㻤 㻞㻠 㻟㻜 㻟㻢

㹔㹍PLPLQ

Time(min)

Multi step 40watt/6min Hyperoxia

Sub. M

)LJከẁ㝵㈇Ⲵ㐠ື୰ࡢ㓟⣲ᦤྲྀ㔞ࡢ୍౛

0 500 1000 1500 2000 2500

㻜 㻢 㻝㻞 㻝㻤 㻞㻠 㻟㻜 㻟㻢

㹔㹍PLPLQ

Time(min)

Multi step 40watt/6min Hyperoxia

Sub. M

)LJከẁ㝵㈇Ⲵ㐠ື୰ࡢ㓟⣲ᦤྲྀ㔞ࡢ୍౛

ḟ࡟ࠊྛࢫࢸࢵࣉࡢ㓟⣲ᦤྲྀ㔞࠿ࡽ㸯ࡘ๓ࡢࢫ ࢸࢵࣉࡢ㓟⣲ᦤྲྀ㔞࡜ࡢᕪࢆồࡵࡿࡇ࡜࡟ࡼࡾࠊ 㸯 ࢫ ࢸ ࢵ ࣉ ẖ ࡢ 㓟 ⣲ ᦤ ྲྀ 㔞 ࡢ ቑ ຍ 㔞 ࢆ ồ ࡵ ࡓ ࠋ

(Fig.8) ࡇࡢ್ࡣቑຍࡋࡓ௙஦⋡(Power) 30

ཪࡣ

40Watt

ศ࡟┦ᙜࡍࡿ㓟⣲ᦤྲྀ㔞ࢆ♧ࡍࡶࡢ࡛࠶

ࡿࠋྠࡌ௙஦⋡ࡢຍ⟬࡟ᑐࡋ࡚ࠊ㓟⣲ᦤྲྀ㔞ࡢቑ ຍศࡣྠࡌ࡛ࡣ࡞ࡃࠊ㈇Ⲵᙉᗘ࡟ẚ౛ࡋ࡚ቑຍࡋ

࡚࠸ࡗࡓࠋࡇࡢࡇ࡜ࡣࠊFig.6 ࡛♧ࡋࡓ

Power㸫 V

㸬

O

2㛵ಀ࡟࠾࠸࡚ࠊ┤⥺ⓗ࡞ẚ౛㛵ಀࡼࡾࡶ᭤⥺

ⓗ࡞㛵ಀࡀᙉ࠸ࡇ࡜ࢆព࿡ࡍࡿࠋ

ࡑࡇ࡛ࠊ㈇Ⲵᙉᗘ࡜㓟⣲ᦤྲྀ㔞(Power㸫V㸬

O

2

)㛵

ಀ࡟ࡘ࠸࡚ࠊᅇᖐ┤⥺ཬࡧᅇᖐ᭤⥺ࡢ㏆ఝᘧ࡜┦

㛵ಀᩘࢆồࡵࠊ

Fig.9

࡟♧ࡋࡓࠋ᭤⥺ᅇᖐࡣ஧ḟᘧ

ࢆ⏝࠸ࡓࠋ

Ϩ: ϩZ ϪZ ϫZ ϬZ ϭZ

VO2(ml/min)

䠬䡋䡓䡁䡎

+\SR[LD 1RUPR[LD +\SHUR[LD ^QV

)LJྛ᮲௳ୗ࡛ࡢ㓟⣲ᦤྲྀ㔞㸦ప㓟⣲ୗ࡛ࡣ㸱ྡࡀ㸳ẁ㝵ࡢ㐠ືࢆ⤊஢

࡛ࡁ࡞࠿ࡗࡓࠋࡲࡓࠊྛ᮲௳ୗ㛫࡛ࡢ᭷ព࡞ᕪࡣㄆࡵࡽࢀ࡞࠿ࡗࡓࠋ㸧

0 100 200 300 400 500 600

Ϩ-ϩ ϩ-Ϫ Ϫ-ϫ ϫ-Ϭ Ϭ-ϭ

VO2(ml/min)

Power30,40Wattࡢຍ⟬

Hypoxia Normoxia Hyperoxia

)LJྛࢫࢸࢵࣉ㛫ࡢ㓟⣲ᦤྲྀࡢቑຍ㔞㸬

㸦㈇Ⲵᙉᗘࡢቑຍ࡟క࠸ࠊྠࡌ௙஦㔞ࡢຍ⟬࡟ᑐࡋ࡚ࡶ㓟⣲ᦤྲྀ㔞ࡀቑຍࡋࡓ㸧

ྛࢫࢸࢵࣉ㛫࡛᭷ព࡟ቑຍࡋࡓ

ࡑࡋ࡚ࡇࡢ┦㛵ಀᩘࢆẚ㍑ࡋࠊFig.10࡟♧ࡋ ࡓࠋ┦㛵ಀᩘࡣ

Hypoxia Normoxia Hyperoxia

ࡢ㡰࡟┤⥺ᅇᖐ

0.9951s0.0031ࠊ0.9923s 0.0032ࠊ0.9913s0.0047ࠊ᭤⥺ᅇᖐ 0.9996s 0.0002ࠊ0.9994s0.0005ࠊ0.9995s0.0007

࡛

࠶ࡗࡓࠋࡇࢀࡣ

6

Ⅼࡢᅇᖐ࡛࠶ࡾࠊ୧⪅ඹ࡟㧗

࠸┦㛵ಀᩘࡢ್࡟࡞ࡿࡀࠊ㸱᮲௳ୗඹ࡟ࠊ᭤⥺

ᅇᖐࡣ᭷ព࡟㧗࠸್ࢆ♧ࡋࡓࠋ

Power㸫V

㸬

O

2㛵ಀࢆᇶ࡟┤⥺ᅇᖐ࡜᭤⥺ᅇᖐࢆ

ࡲ࡜ࡵࡓࡶࡢࡀ

Fig.11

࡛࠶ࡿࠋᶓ㍈ࡣ㈇Ⲵᙉᗘ

࡛࠶ࡿࡀࠊV㸬

O

2

max

࡟┦ᙜࡍࡿ㓟⣲ᦤྲྀ㔞ࡢᙉ

ᗘࢆ

100%࡜ࡋ࡚ゎᯒࡋࡓࠋྛࢫࢸࢵࣉࡢ㓟⣲ᦤ

ྲྀ㔞ࡣ

Fig.7

࡛♧ࡋࡓࡼ࠺࡟ప㓟⣲ࠊ㏻ᖖ኱Ẽཬ

ࡧ㧘㓟⣲ୗ࡟࠾࠸࡚᭷ព࡞ᕪࡣㄆࡵࡽࢀ࡞࠸ࠋࡇ

ࢀࢆ┤⥺ཪࡣ᭤⥺ࡢ㏆ఝᘧ࡛ᅇᖐࡍࡿ࡜ࠊ㧘ᙉᗘ

࡟࡞ࡿ࡟ࡘࢀ࡚ᕪࡀ኱ࡁࡃ㛤࠸࡚࠸ࡃࠋ

㼥㻌㻩㻌㻜㻚㻜㻞㻝㻢㻌㼤^㻞㻗㻌㻣㻚㻟㻥㻠㻌㼤㻌㻗㻌㻠㻢㻤㻚㻣㻌 㻾^㻞㻩㻌㻜㻚㻥㻥㻥㻞㻌

㼥㻌㻩㻌㻝㻜㻚㻣㻤㻤㼤㻌㻗㻌㻠㻜㻞㻚㻝 㻾^㻞㻩㻌㻜㻚㻥㻥㻜㻢

92POPLQ

3㹭㹵㹣㹰ZDWW 㻴㼥㼜㼛㼤㼕㼍

+\SR[LD

஧ḟ᭤⥺ᅇᖐ 6XE㻚㼀㻚㻵 ┤⥺ᅇᖐ

㼥㻌㻩㻌㻜㻚㻜㻝㻤㻡㻌㼤^㻞㻗㻌㻣㻚㻤㻞㻤㻌㼤㻌㻗㻌㻠㻤㻤㻚㻞㻌 㻾^㻞㻩㻌㻜㻚㻥㻥㻥㻥㻌

㼥㻌㻩㻌㻝㻝㻚㻠㻡㻢㼤㻌㻗㻌㻟㻥㻟㻚㻠 㻾^㻞㻩㻌㻜㻚㻥㻥㻝㻡

92POPLQ

3㹭㹵㹣㹰ZDWW 㻺㼛㼞㼙㼛㼤㼕㼍

1RUPR[LD

஧ḟ᭤⥺ᅇᖐ

┤⥺ᅇᖐ

㼥㻌㻩㻌㻜㻚㻜㻞㻡㻥㻌㼤^㻞㻗㻌㻢㻚㻟㻣㻢㻌㼤㻌㻗㻌㻠㻥㻝㻚㻝㻌 㻾^㻞㻩㻌㻜㻚㻥㻥㻥㻞㻌

㼥㻌㻩㻌㻝㻝㻚㻠㻠㻤㼤㻌㻗㻌㻟㻡㻤㻚㻡 㻾^㻞㻩㻌㻜㻚㻥㻤㻞㻤

92POPLQ

3㹭㹵㹣㹰ZDWW 㻴㼥㼜㼑㼞㼛㼤㼕㼍

+\SHUR[LD

஧ḟ᭤⥺ᅇᖐ

┤⥺ᅇᖐ

Fig.9.௙஦⋡࡟ᑐࡍࡿ㓟⣲ᦤྲྀ㔞㛵ಀࡢ┤⥺ཬࡧ

஧ḟ᭤⥺ᅇᖐࡢ୍౛

+\SR[LD 1RUPR[LD +\SHUR[LD

㹰

┤⥺ᅇᖐ ஧ḟ᭤⥺ᅇᖐ

䓊䠆䠆䓎 䓊䠆䠆䓎 䓊䠆䠆䓎

㻖㻖㻦䠬䠘㻜㻚㻜㻝 )LJ௙஦⋡㸫㓟⣲ᦤྲྀ㔞㛵ಀ࡟࠾ࡅࡿ㏆ఝᘧࠊ

┤⥺ᅇᖐཬࡧ஧ḟ᭤⥺ᅇᖐࡢ┦㛵ಀᩘࡢẚ㍑

92POPLQ

3RZHU92PD[

䠬䡋䡓䡁䡎㻙㼂㻻㻞 㛵ಀ

㻴㼥㼜㼛㼤㼕㼍 㻺㼛㼞㼙㼛㼤㼕㼍 㻴㼥㼜㼑㼞㼛㼤㼕㼍 ከ㡯ᘧ 㻔㻴㼥㼜㼛㼤㼕㼍㻕

⥺ᙧ 㻔㻴㼥㼜㼛㼤㼕㼍㻕 ከ㡯ᘧ 㻔㻺㼛㼞㼙㼛㼤㼕㼍㻕

⥺ᙧ 㻔㻺㼛㼞㼙㼛㼤㼕㼍㻕 ከ㡯ᘧ 㻔㻴㼥㼜㼑㼞㼛㼤㼕㼍㻕

⥺ᙧ 㻔㻴㼥㼜㼑㼞㼛㼤㼕㼍㻕

)LJప㓟⣲ࠊ኱Ẽࠊ㧗㓟⣲᮲௳ୗ࡟࠾ࡅࡿ

3RZHU㸫92㛵ಀࡢ┤⥺ᅇᖐ࡜஧ḟ᭤⥺ᅇᖐ

஧ḟ᭤⥺ᅇᖐ

┤⥺ᅇᖐ

㏻ᖖ኱Ẽୗࢆ౛࡜ࡋ࡚ࠊ┤⥺ᅇᖐཬࡧ᭤⥺ᅇᖐ ࡢ ㏆ ఝ ᘧ ࠿ ࡽ ồ ࡵ ࡓ 㐠 ື ᫬ ࡢ 㓟 ⣲ 㟂 せ 㔞 ࡢ ್ ࢆ

Fig.12

࡟♧ࡋࡓࠋ

V

㸬

O

2

max

࡟┦ᙜࡍࡿ㈇Ⲵᙉᗘ

(100%)

࡛ ࡣ ᭤ ⥺ ᅇᖐ ࠿ࡽ ồ ࡵࡓ 㓟⣲ 㟂 せ㔞 ࡣ┤

⥺ᅇᖐ࠿ࡽồࡵࡓ್ࡼࡾ

373s148ml/minࠊ 12.7%

㧗ࡃ࡞ࡗࡓࠋࡲࡓࠊV㸬

O

2

max

ࡢ

150%࡟┦ᙜࡍࡿ

ᙉᗘ࡟࠾࠸࡚ࡣࠊ1286s359ml/minࠊ30.4%㧗࠸

್࡜࡞ࡗࡓࠋ

Fig. 13

࡟ࢫࢸࢵࣉ㈇Ⲵ㐠ື୰ࡢᚰᢿᩘࢆ♧ࡋ

ࡓࠋప㓟⣲ࠊ㏻ᖖ኱Ẽࠊ㧘㓟⣲ࡢ㡰࡟ᚰᢿᩘࡣ᭷

ព࡟ప࠸್࡜࡞ࡗࡓࠋ5 ࢫࢸࢵࣉ┠࡛ࡢᚰᢿᩘࡣ ప㓟⣲

168.0s13.4ࠊ㏻ᖖ኱Ẽ 155.4s12.2ࠊ㧘㓟

⣲

147.2s12.9ࠊ᭱⤊ 6

ࢫࢸࢵࣉ࡛ࡣ㏻ᖖ኱Ẽ

177.8s13.4ࠊ㧘㓟⣲ 170.4s13.2(bpm)࡛࠶ࡗࡓࠋ

Fig.14

࡟ࢫࢸࢵࣉ㈇Ⲵ㐠ື୰ࡢ᥮Ẽ㔞ࢆ♧ࡋࡓࠋ

2

ࢫࢸࢵࣉ௨㝆࡟ࡘ࠸࡚ࠊప㓟⣲᮲௳ࡣ௚࡟ẚ࡭

࡚᥮Ẽ㔞ࡀ᭷ព࡟㧗࠸್࡟࡞ࡗࡓࠋ5 ࢫࢸࢵࣉ┠

࡛ࡢ᥮Ẽ㔞ࡣప㓟⣲

69.1s8.8ࠊ㏻ᖖ኱Ẽ 55.1s 4.4ࠊ㧘㓟⣲ 54.4s5.8(l/min)࡛࠶ࡗࡓࠋ㏻ᖖ኱Ẽ

࡜㧘㓟⣲᮲௳ୗ࡟࠾࠸࡚ࡣࡑࢀࡒࢀࡢࢫࢸࢵࣉ࡟

࠾࠸࡚ࠊ᥮Ẽ㔞࡟᭷ព࡞ᕪࡣㄆࡵࡽࢀ࡞࠿ࡗࡓࠋ ࡋ࠿ࡋ࡞ࡀࡽࠊ᭱⤊

6

ࢫࢸࢵࣉ࡛ࡣ㏻ᖖ኱Ẽ

78.1

s9.9ࠊ㧘㓟⣲

73.7s11.7(l/min)࡜ࠊ᭷ពࡣ♧ࡉࢀ

࡞࠿ࡗࡓࡀࠊ᭷ពᕪࡢ༴㝤⋡

p

ࡣ

0.07

࡜ࡑࡢഴ

ྥࢆ♧ࡋࡓࠋ

㹔㹍POPLQ

㹎㹭㹵㹣㹰㸣92PD[

䠫㻞䡀䡁䡉䠽䡊䡀

஧ḟ᭤⥺ᅇᖐ

┤⥺ᅇᖐ

ᕪศ _㻖㻖

㻖㻖 㻖㻖

㻖㻖 㻖

㻖㻖

)LJ┤⥺ᅇᖐཬࡧ஧ḟ᭤⥺ᅇᖐࢆ⏝࠸ࡓ㐠ື᫬ࡢ㓟⣲㟂せ㔞ࡢẚ㍑

㸦㹔㹍PD[Ⓨ᥹᫬ࡢ㈇Ⲵࢆ㉺࠼ࡿ㐠ື࡛ࡣ኱ࡁ࡞ᕪ࡜࡞ࡿ㸧 Normoxia

䊠㻔㻜㼃㻕 䊡㻔㻟㻜㻘㻠㻜㼣㻕 䊢㻔㻢㻜㻘㻤㻜㼣㻕 䊣㻔㻥㻜㻘㻝㻞㻜㼣㻕 䊤㻔㻝㻞㻜㻘㻝㻢㻜㼣㻕 䊥㻔㻝㻡㻜㻘㻞㻜㻜㼣㻕

ᚰᢿᩘ㹆㹐(㹠㹮㹫)

䠬䡋䡓䡁䡎 㻴㼥㼜㼛㼤㼕㼍 㻺㼛㼞㼙㼛㼤㼕㼍 㻴㼥㼜㼑㼞㼛㼤㼕㼍

䓊㻙㻙 㻖 㻙㻙䓎

䓊㻙㻙 㻖㻖㻌㻙㻙䓎

䓊㻙㻙 㻖 㻙㻙䓎 䓊㻙㻙 㻖 㻙㻙䓎

䓊㻙㻙 㻖㻖㻌㻙㻙䓎 䓊㻖㻖䓎

䓊㻌㻖 䓎

䓊㻖㻖䓎

䓊㻖㻖䓎

䓊㻌㻖 䓎

㻖㻌㻦㻌㼜㻨㻜㻚㻜㻡 䓊㻌㻖 䓎

n=5

4

⪃ᐹ

㐠ືࢆ㛤ጞࡋࡓࡾ㐠ືᙉᗘࡀቑຍࡋࡓࡾࡍࡿ࡜

᪂ࡓ࡞࢚ࢿࣝࢠ࣮ࡀᚲせ࡜࡞ࡿࠋࡇࡢ㟂せ࡟ᑐࡋ

࡚ࠊ⏕య࡛ࡣ࿧྾ᚠ⎔ᶵ⬟ࡀᛂ⟅ࡋࠊ㐜ࢀ࡞ࡀࡽ

ࡶ㓟⣲ᦤྲྀ㔞ࡣቑຍࡍࡿ³⁾ࠋࡇࡢ㓟⣲㟂せ㔞࡜㓟

⣲ᦤྲྀ㔞ࡀ➼ࡋࡃ࡞ࢀࡤᐃᖖ≧ែࡀ⥔ᣢ࡛ࡁࠊ᭷

㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡢ౪⤥࡟ࡼࡗ࡚㐠ືࡀ⥆ࡅࡽࢀ

ࡿࠋ

㧗ᙉᗘࡢ㐠ື࡟࠾࠸࡚ࡣ㓟⣲㟂せ㔞࡟ᑐࡋ㓟⣲

ᦤྲྀ㔞ࡀ㊊ࡽࡎࠊ↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡀືဨࡉࢀ

ࡿࠋࡇࡢ↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡣᐜ㔞࡟ไ㝈ࡀ࠶

ࡾࠊࡇࢀࢆ౑࠸ᯝࡓࡍࡼ࠺࡞᭱኱㓟⣲೉࡟㐩ࡍࡿ

࡜ࡇࡢࣞ࣋ࣝࡢ㐠ືᙉᗘࡀ⥔ᣢ࡛ࡁ࡞ࡃ࡞ࡿ⁴⁾ࠋ ࢚ࢿࣝࢠ࣮ㄽⓗ࡟ࡣࠊ᭱኱ດຊࡢ㐠ື࡛ࡣࠊ᭷

㓟⣲ᛶ⬟ຊ࡜↓㓟⣲ᛶ⬟ຊࡢ୧᪉ࡀᚲせ࡜࡞ࡿࠋ

᭷㓟⣲ᛶ⬟ຊࡢᣦᶆ࡛࠶ࡿ㓟⣲ᦤྲྀ㔞ࡣ᫬㛫ᙜࡓ

ࡾࡢ್࡛࠶ࡾࠊ༢఩ࡣ

ml/min(/kg)࡛࠶ࡿࠋ↓㓟⣲

ᛶ⬟ຊࡢᣦᶆ࡛࠶ࡿ㓟⣲೉ࡸ㓟⣲㈇മࡣ㸯ᅇࡢᐜ 㔞࡛࠶ࡾࠊ༢఩ࡣ

ml(/kg)࡛࠶ࡿࠋࡋࡓࡀࡗ࡚ࠊ㛗

㊥㞳㉮ࡢࡼ࠺࡟㛗࠸᫬㛫ࡢ㐠ື࡛ࡣࠊ᭷㓟⣲ᛶ⬟

ຊࡢ㈉⊩ᗘࡣ኱ࡁࡃ࡞ࡿࠋ㛗㊥㞳㉮⪅ࡢ᭱኱㓟⣲

ᦤྲྀ㔞ࡀ㧗࠸ࡇ࡜ࡣࠊࡼࡃ▱ࡽࢀࡓࡇ࡜࡛࠶ࡿࠋ

㏫࡟▷᫬㛫ࡢ㐠ື࡛ࡣࠊ↓㓟⣲ᛶ⬟ຊࡢ㈉⊩ᗘࡀ

኱ࡁࡃ࡞ࡿࠋణࡋࠊ࠿࡞ࡾ▷࠸ᩘ⛊⛬ࡢ㐠ື࡟࡞

ࡿ࡜ࠊ↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࢆ඲࡚౑࠸ᯝࡓࡉࡎ࡟

㐠ືࡀ⤊஢ࡍࡿࡓࡵࠊ୧⪅ࡢ࢚ࢿࣝࢠ࣮⬟ຊࡣไ 㝈ᅉᏊ࡟࡞ࡽ࡞࠸ࠋ

ࡇࡢ↓㓟⣲ᛶ⬟ຊࡢᣦᶆ࡛࠶ࡿ㓟⣲೉ࢆ ᐃࡍ

ࡿ࡟ࡣࠊ㐠ື୰ࡢ㓟⣲㟂せࢆṇ☜࡟ぢ✚ࡶࡿᚲせ ࡀ࠶ࡿࠋ᭱኱㓟⣲೉ࡢ ᐃ࡟ࡣࠊV

㸬

O

2

max

Ⓨ᥹᫬

ࢆ㉺࠼ࡿ㧗࠸ᙉᗘ࡛ࡢ㓟⣲㟂せ㔞ࡢ᥎ᐃ್ࡀᚲせ

࡜࡞ࡿࠋ

ᮏ◊✲࡛ࡣࠊ␗࡞ࡿ㓟⣲⃰ᗘࢆ྾Ẽ࡜ࡋࠊ᭱኱

௨ୗࡢࢫࢸࢵࣉ㈇Ⲵ㐠ືࢆ⾜࠸ࠊࡑࡢᐃᖖ≧ែ࡛

ࡢ㓟⣲ᦤྲྀ㔞ཬࡧ࢞ࢫ஺᥮ㅖ㔞ࢆ ᐃࡋࡓࠋ୍⯡

࡟ࠊప㓟⣲⎔ቃୗ࡟࠾࠸࡚ࡣ㓟⣲ᦤྲྀ⬟ຊࡀᢚไ ࡉࢀࠊᣢஂⓗࣃࣇ࢛࣮࣐ࣥࢫࡣపୗࡍࡿࠋ㏫࡟㧗 㓟⣲⎔ቃୗ࡛ࡣ㓟⣲౪⤥ࡀᐜ᫆࡟࡞ࡾࠊ㧗࠸ࣞ࣋

ࣝࡢᐃᖖ㐠ືࡀྍ⬟࡟࡞ࡿ࡜⪃࠼ࡽࢀࡿࠋࡋ࠿ࡋ

࡞ࡀࡽࠊᮏᐇ㦂࡛ࡢ㓟⣲ᦤྲྀ㔞ࡣప㓟⣲ཬࡧ㧗㓟

⣲ ྾ ධ ࡟ ࠾ ࠸ ࡚ ᕪ ࡀ ㄆ ࡵ ࡽ ࢀ ࡞ ࠿ ࡗ ࡓ ࠋ(Fig.7) 㸴ẁ㝵┠ࡢ㈇Ⲵᙉᗘ࡛ࡣࠊప㓟⣲ୗ࡟࠾࠸࡚ࡣ㐠

ືࡀ⥅⥆࡛ࡁ࡞ࡃ࡞ࡾᕪࡀ࡛ࡁࡓࡶࡢࡢࠊ㧗㓟⣲

ୗ࡛ࡣ㓟⣲ᦤྲྀ㔞ࡣ᭷ព࡟㧗࠸್࡟ࡣ࡞ࡽ࡞࠿ࡗ ࡓࠋ

ࡘࡲࡾࠊྠࡌ㈇Ⲵᙉᗘ࡟࠾࠸࡚ࡣྠࡌ࢚ࢿࣝࢠ

࣮ࡀᚲせ࡜࡞ࡾࠊᐃᖖ≧ែࡀ⥔ᣢࡉࢀ࡚࠸ࢀࡤྠ

ࡌ㓟⣲㟂せ㔞࡟ᑐࡍࡿ㓟⣲ᦤྲྀ㔞ࡣྠࡌ࡟࡞ࡿࢃ

ࡅ࡛࠶ࡿࠋ௬࡟ࠊ㧗㓟⣲ࢆ౑࠺ࡇ࡜࡛᭦࡟㧗࠸ᙉ ᗘ࡛ࡢᐃᖖ≧ែࡢ㓟⣲ᦤྲྀ㔞ࡀ ᐃ࡛ࡁࢀࡤࠊ᪂ ࡓ࡞ホ౯ࢆຍ࠼ࡿࡇ࡜ࡀ࡛ࡁࡿࠋ௒ᚋࡢㄢ㢟࡛࠶

ࡿࠋ

Fig13.ཬࡧ Fig.14

࡛♧ࡋࡓࡼ࠺࡟ࠊᚰᢿᩘཬࡧ

᥮Ẽ㔞ࡢ࿧྾ᚠ⎔⣔ࡢ್ࡣ྾Ẽࡢ㓟⣲⃰ᗘ㛫࡟࠾

࠸࡚ᕪࡀㄆࡵࡽࢀࡓࠋࡇࢀࡣప㓟⣲࡟ẚ࡭㧗㓟⣲

䊠㻔㻜㼃㻕 䊡㻔㻟㻜㻘㻠㻜㼣㻕 䊢㻔㻢㻜㻘㻤㻜㼣㻕 䊣㻔㻥㻜㻘㻝㻞㻜㼣㻕 䊤㻔㻝㻞㻜㻘㻝㻢㻜㼣㻕 䊥㻔㻝㻡㻜㻘㻞㻜㻜㼣㻕

᥮Ẽ㔞9(OPLQ

㻴㼥㼜㼛㼤㼕㼍 㻺㼛㼞㼙㼛㼤㼕㼍 㻴㼥㼜㼑㼞㼛㼤㼕㼍

Fig.14.ప㓟⣲ࠊ኱Ẽࠊ㧗㓟⣲᮲௳ୗ࡛ࡢ᥮Ẽ㔞

䓊㻌㻖 䓎

䓊㻙㻙㻖㻖㻙㻙䓎

䓊㻙㻙 㻖 㻙㻙䓎

䓊㻙㻙㻖㻖㻙㻙䓎 䓊㻖㻖䓎

䓊㻖㻖䓎

䓊㻖㻖䓎

㻖㻌㻦㻌㼜㻨㻜㻚㻜㻡 㻖㻖㻌㻦㻌㼜㻨㻜㻚㻜㻝

n=7

⎔ቃୗࡢ᪉ࡀ⏕య࡟㈇ᢸࡢᑡ࡞࠸≧ែ࡛㐠ືࡀᐇ

᪋࡛ࡁࡿࡇ࡜ࢆព࿡ࡍࡿࠋ

ࡇࡢ㐠ື࡟ᚲせ࡞࢚ࢿࣝࢠ࣮ࡣࠊ⮬㌿㌴࢚ࣝࢦ

࣓࣮ࢱ࣮࡟௙஦ࢆฟຊࡉࡏࡿእⓗ࡞௙஦㔞࡜యࢆ

ື࠿ࡍෆⓗ௙஦㔞ࠊࡑࢀ࡟ຍ࠼ᚰ➽ࡸ࿧྾➽ࢆά

ືࡉࡏࡿ⏕⌮ⓗ࡞௙஦㔞ࡢ⥲㔞࡛࠶ࡾࠊ㓟⣲㟂せ 㔞࡛࠶ࡿࠋ

Fig.7

࡛♧ࡋࡓࡼ࠺࡟㓟⣲㟂せ㔞ࡣྠࡌ

࡛ࠊ⏕⌮ⓗ࡞௙஦࡟ᕪࡀ࠶ࡿ࡜ࡍࡿ࡜

Power

࡛⾲

ࡋࡓ≀⌮ⓗ࡞௙஦ࡢࡓࡵࡢ㓟⣲㟂せ㔞࡟ᕪࡀ࡛ࡁ

࡚ࡋࡲ࠺ࠋ㧗㓟⣲ୗࡢ᪉ࡀప㓟⣲ୗࡼࡾࡶ㓟⣲ᦤ

ྲྀ㔞ࡀከ࠸ࡇ࡜࡟࡞ࡿࠋヲ⣽࡞ྫྷ࿡ࡀᚲせ࡛࠶ࡾࠊ

௒ᚋࡢㄢ㢟࡛࠶ࡿࠋ

௬ㄝ࡜ࡋ࡚ࠊ⏕యࡣ࠸ࡘ࡛ࡶ㓟⣲㟂せ㔞࡜ྠ㔞 ࡢ㓟⣲ࢆᦤྲྀࡍࡿࡼ࠺࡟࿧྾ᚠ⎔ᶵ⬟ࢆ↓⌮࡟ஹ 㐍ࡉࡏࡿࡢ࡛࠶ࢁ࠺࠿ࠋ᭷㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࡔࡅ

࡟㢗ࡽࡎࠊ↓㓟⣲ᛶ࢚ࢿࣝࢠ࣮ࢆືဨࡋ࡚ࠊ㐠ື

ᚋ࡟㓟⣲ࢆ㏉῭ࡋࡓ᪉ࡀ⏕య࡟࡜ࡗ࡚㈇ᢸ࡟࡞ࡽ

࡞࠸࡛ࡣ࡞࠸࠿ࠋ㧗࠸㐠ືᙉᗘ࡟࠾࠸࡚

V

㸬

O

2ࡀ⦆

ࡸ࠿࡟ቑ኱ࡍࡿ

slow component

ࡢၥ㢟ࡶࡇࡢࡇ

࡜࡜㛵㐃ࡀ῝࠸࡜⪃࠼ࡽࢀࡿࠋ

㓟⣲㟂せ㔞ࡢ㏆ఝᘧࡢࡓࡵࡢ

Power㸫V

㸬

O

2㛵ಀ ࡢ ᐃ᪉ἲ࡟ࡘ࠸࡚ࠊMedbo⁵⁾ࡽࡢ᪉ἲ࡛ࡣ

V

㸬

O

2

maxࡢ 40㹼90%࡟┦ᙜࡍࡿᙉᗘࡢࢫࢸࢵࣉ

㈇Ⲵࢆ ࠿ࡽ ᅇࡑࢀࡒࢀ ศ㛫ࢆ⾜࠸┤⥺ᅇ ᖐࡋ࡚࠸ࡿࠋᮏᐇ㦂࡛ࡣ ศ㛫ẖ࡟₞ቑࡍࡿ ẁ 㝵ࢫࢸࢵࣉ㈇Ⲵࢆ⏝࠸ࡓࠋ ᅇࡢ ᐃ࡟࡚㏆ఝᘧ ࡀồࡵࡽࢀࡿ฼Ⅼࡀ࠶ࡗࡓࠋྛࢫࢸࢵࣉࡢ᫬㛫ࠊ ከẁ㝵ࢫࢸࢵࣉࡢ᪉ᘧࡢ㐪࠸ࢆ᳨ウࡋ࡚࠸ࡁࡓ

࠸ࠋ

Fig.8

࡛♧ࡋࡓࡼ࠺࡟ྠࡌ௙஦⋡ࡢຍ⟬࡟ᑐࡋ

࡚ࠊ㓟⣲ᦤྲྀ㔞ࡢቑຍศࡣྠࡌ࡛ࡣ࡞ࡃࠊ㈇Ⲵᙉ ᗘ࡟ẚ౛ࡋ࡚ቑຍࡋ࡚࠸ࡗࡓࠋࡇࢀࡣ㐠ືᙉᗘࡀ 㧗࠸࡯࠺ࡀ࢚ࢿࣝࢠ࣮ࡢࢥࢫࢺࡀ࠿࠿ࡿ࡜࠸࠺ࡇ

࡜࡟࡞ࡿࠋࡇࡢࢹ࣮ࢱࢆ᰿ᣐ࡟

Power㸫V

㸬

O

2㛵ಀ

ࢆ஧ḟ᭤⥺࡛㏆ఝࡋࠊ⢭ᗘࡢ㧗࠸㓟⣲㟂せ㔞ࡢ᥎ ᐃ᪉ἲࢆᚓࡽࢀࡓࡇ࡜ࡣព⩏ࡢ࠶ࡿࡇ࡜࡛࠶ࡗ ࡓࠋ(Fig.9,10,11,)

ࡇࡢ᭤⥺ᅇᖐࡢ㏆ఝᘧ࡛ồࡵࡓ㓟⣲㟂せ㔞ࡣ┤

⥺ᅇᖐ࡟ẚ࡭࡚ࠊV㸬

O

2

max

ࡢ

125

ཬࡧ

150%┦ᙜ

ࡍࡿ㈇Ⲵᙉᗘ࡟࠾࠸࡚ࡣࠊ

21.4

ཬࡧ

30.4㸣㧗ࡃ᥎

ᐃࡉࢀࡓࠋࡇࢀࡽࡢࡇ࡜࠿ࡽࠊ㓟⣲㟂せ㔞ࡢホ౯ ᪉ἲ࡟࠾࠸࡚

Power㸫V

㸬

O

2㛵ಀࢆぢ┤ࡍᚲせࡀ࠶

ࡿ࡜⪃࠼ࡽࢀࡿࠋ

5

ࡲ࡜ࡵ

࣭ᮏ◊✲࡛ࡣࠊከẁ㝵ࢫࢸࢵࣉ㈇Ⲵ㐠ື࡟࠾ࡅࡿ

Power㸫V

㸬

O

2 㛵ಀ࡟ཬࡰࡍప㓟⣲ཬࡧ㧗㓟⣲࢞

ࢫ྾ධࡢᙳ㡪࡜㧗ᙉᗘ㐠ື᫬ࡢ㓟⣲㟂せ㔞ࡢホ ౯࡟ࡘ࠸᳨࡚ウࡋࡓࠋ

࣭㸴ศ㛫ࡢྛࢫࢸࢵࣉ㈇Ⲵ㐠ືࡢ᭱⤊㸰ศ㛫ࡢ㓟

⣲ᦤྲྀ㔞ࡣࠊ྾Ẽࡢ㓟⣲⃰ᗘࡢ㐪࠸࡟ࡼࡿᕪࡣ ㄆࡵࡽࢀ࡞࠿ࡗࡓࠋ

࣭ᚰᢿᩘ࡜᥮Ẽ㔞ࡣ྾Ẽࡢ㓟⣲⃰ᗘࡢቑຍ࡟క࠸ࠊ ప࠸್࡜࡞ࡿഴྥࢆࡋࠊ⏕య࡜ࡗ࡚㈇ᢸࡢᑡ࡞

࠸ᐜ᫆࡞㐠ືࡀྍ⬟࡟࡞ࡿࡇ࡜ࡀ♧၀ࡉࢀࡓࠋ

࣭Power㸫V㸬

O

2 㛵ಀࡣ஧ḟከ㡯ᘧࡢ㏆ఝࢆ⏝࠸ࡓ

᭤⥺ᅇᖐ࡟ࡼࡾࠊ㧗⢭ᗘࡢ㓟⣲㟂せ㔞ࡢ ᐃࡀ

ྍ⬟࡜࡞ࡗࡓࠋ

࣭V㸬

O

2

max

ࢆ㉺࠼ࡿ㧗ᙉᗘ㐠ື᫬ࡢ㓟⣲㟂せ㔞ࡣ ࡇࢀࡲ࡛ࡢᐃᖖୗ┤⥺ᅇᖐ࡟ࡼࡿ᥎ᐃ್ࡼࡾࡶ

㧗࠸್࡛࠶ࡿ࡜⪃࠼ࡽࢀࡿࠋ

ㅰ㎡

ᮏ◊✲ࡢᐇ᪋࡟㝿ࡋࠊከ኱࡞ࡿࡈᑾຊ࡜ࡈᣦᑟ

ࢆ㡬ࡁࡲࡋࡓ㇏ᶫᢏ⾡⛉Ꮫ኱Ꮫྡ㄃ᩍᤵࡢᏳ⏣ዲ

ᩥඛ⏕࡟ࠊᚰࡼࡾឤㅰ⏦ࡋୖࡆࡲࡍࠋ

ᘬ⏝ᩥ⊩

1) DAVID C. POOLE :Role of exercising muscle in slow component of V

㸬

O

2

. Med.Sci.Sports Exerc. 1335- 1340 (1994)

2) GREEN,S.and B.T.DAWSON : The oxygen uptake- power regression in cyclists and untrained men implications for the accumulated oxygen deficit.

Eur.J.Appl.Phyiol. 70:351-359 (1995)

3)

ఀ⸨ᬛᘧࠊᑠ㔝㝯ࠊᏳ⏣ዲᩥ㸸ࣛࣥࣉ㈇Ⲵ㐠ືࢆ⏝࠸

ࡓ࢔ࢿࣟࣅࢵࢡ࢟ࣕࣃࢩࢸ࢕࣮᥎ᐃἲࡢ᳨ウ㸬యຊ⛉

Ꮫ Vol.45 NO.6,688 (1996)

4)

ఀ⸨ᬛᘧࠊᏳ⏣ዲᩥ㸸᭱኱㐠ືᚋࡢఇᜥ᫬㛫࡜↓㓟⣲

࢚ ࢿ ࣝ ࢠ ࣮ ࡢ ᅇ ᚟ 㐣 ⛬ 㸬 ឡ ▱ Ꮫ Ἠ ኱ Ꮫ 㺃 ▷ ᮇ ኱ Ꮫ ⣖ せ,No.47:7-14 (2012)

5) MEDBO,J.I.,et al : Anaerobic capacity determined by maximal accumulated O

㸰

deficit.

J.Appl.Physiol. 64(1):50-60 (1988)

6) MEDBO,J.I.and I.TABATA : Relative importance of

aerobic and anerobic energy release during short-

7)

Ᏻ⏣ዲᩥࠊ⏣ᮧᡂ᫛ࠊすᒸᑗ㍤㸸 ࣐࢖ࢡࣟࢥࣥࣆ࣮ࣗ

ࢱࢆ⏝࠸ࡓ⮬ືไᚚᆺ⮬㌿㌴࢚ࣝࢦ࣓࣮ࢱࡢ㛤Ⓨ㸬㇏

ᶫ ᢏ ⾡ ⛉ Ꮫ ኱ Ꮫ ே ᩥ ♫ ఍ ᕤ Ꮫ ⣔ ⣖ せ

,12:130-141 (1990)

ཧ⪃ᩥ⊩

BARSTOW,T.J.:Characterization of VO

㸰

kinetics during heavy exercise. Med.Sci.Sports Exerc.

26(11):1327-1334 (1994)

Eves N. D., Petersen S. R., Jones R. L.: The effect of hyperoxia on submaximal exercise with the self containde breathing apparatus. Ergonomics 45, 840- 849 (2002)

Grataloup O., Prieur F., Busso T., Castells J., Favier F.

B., Denis C., Benoit H.: Effect of hyperoxia on Maximal O

2

uptake in exercise-induced arterial hypoxaemic subjects. Eur J Appl Physiol 94:641-645 (2005) GREEN,S.and B.T.DAWSON : Measurement of Anaerobic Capacities in Humans. Sports Medicine 15(5):312-327 (1993)

GREEN,S., D.BISHOP, and D.JENKINS : Effect of end-point cadence on the maximal work-time relationship. Eur.J.Appl.Phyiol. 71:559-561 (1995)

GREEN,S., B.T.DAWSON, C.GOODMAN,and M.F.CAREY : Anaerbic ATP production and accumulated O

㸰

deficit in cyclists. Med.Sci.Sports Exerc. 28(3):315-321 (1996)

GREEN,S.and B.T.DAWSON : Methodological effects on the VO

㸰

-power regression and the accumulated O

㸰

deficit. Med.Sci.Sports Exerc.28(3):392-397 (1996) JERZY,A.ZOLADZ,et al: Non-linear relationship between O

㸰

uptake and power output at high

intensities of exercise in humans. J.Physiol. 488(1):211- 217 (1995)

MEDBO,J.I.and S.BURGERS : Effect of training on the anaerobic capacity. Med.Sci.Sports Exerc.

22(4):501-507 (1990

᳃೺୍ࠊྜྷᒸ฼㈉ࠊⓑᯇᏹ㍜ࠊⱉᒣ㟹ࠊᑿ⦩㈉㸸᭷㓟⣲ᛶ

⬟ຊࡢ┦㐪ࡀ Wingate test ࡟࠾ࡅࡿ࢚ࢿࣝࢠ࣮౪⤥ẚ࡟

ཬࡰࡍᙳ㡪㸬యຊ⛉Ꮫ

60(5), 503-510 (2011)

᳃೺୍ࠊྜྷᒸ฼㈉ࠊⱉᒣ㟹ࠊᑿ⦩㈉㸸▷㊥㞳㉮⪅࡟࠾ࡅࡿ

↓ 㓟 ⣲ ᛶ ⬟ ຊ ࠾ ࡼ ࡧ ㉮ ࣃ ࣇ ࢛ ࣮ ࣐ ࣥ ࢫ ホ ౯ ࡜ ࡋ ࡚ ࡢ

Wingate test

ࡢ᭷⏝ᛶ㸬యຊ⛉Ꮫ

60(5), 503-510 (2011)

㛗⏣᭸ᶞࠊᑠ಴⿱ྖࠊᙧᮏ㟼ኵࠊෆ⸨ஂኈ㸸␗࡞ࡿప㓟⣲

57(6), 818(2008)

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2

uptake and work capacity. Scand J Med Sci Sports 13:339-358 (2003)

ᑠᕝ๛ྖࠊᯘᜨႹࠊ㘠಴㈼἞ࠊすಖᓅ㸸పᅽ⎔ቃୗ࡟࠾ࡅ

ࡿ▷᫬㛫㧗ᙉᗘ㐠ື᫬ࡢࣃࣇ࢛࣮࣐ࣥࢫ࠾ࡼࡧ࿧྾௦ㅰ ᛂ⟅㸬యຊ⛉Ꮫ

52(6), 725, (2003)

OHIRAR, Y. and TABATA, I.

㸸

Muscle Metabolism during Exercise : Anaerobic Threshold Does Not Exist.

Applied Human Science 11(3), 319-323(1992) Peltonen J. E., Tikkanen H.O., Rusko H. K. : Cardiorespiratory responses to exercise in acute hypoxia, hyperoxia and normoxia. Eur J Appl Physiol 85,82-88 (2001)

POOLE,D.C. : Role of exercising muscle in slow component of VO

㸰

. Med.Sci.Sports Exerc. 26(11): 1335- 1340 (1994)

POOLE,D.C., T.J.BARSTOW, G.A.GAESSER, W.T.WILLIS, and B.J.WHIPP : VO

㸰

slow component physiological and function significance. Med.Sci.Sports Exerc.26(11):1354-1358 (1994)

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ⓑ஭♸௓ࠊ㘠಴㈼἞㸸࣮ࣟ࢖ࣥࢢ᫬ࡢ㓟⣲㟂せ㔞ࡢ᥎ᐃ᪉ ἲ࡟㛵ࡍࡿ᳨ウ㸬య⫱ ᐃホ౯◊✲

15(0),11-23 (2016)

ⓑᮌ㥴భࠊᑿ⦩㈉ࠊᮌ㉺Ύಙ㸸▷᫬㛫㧗ᙉᗘ㐠ື࡟࠾ࡅ

ࡿ㐠ືᙉᗘ࡜࢚ࢿࣝࢠ࣮౪⤥ẚ⋡࡜ࡢ㛵ಀ㸬య⫱Ꮫ◊✲

63,433-440 (2018)

TABATA. I., et al: Effects of moderate-intensity endurance and high-intensity intermittent training on anaerobic capacity and VO

㸰

max. Med.Sci.Sports Exerc.

28(10):1327-1330 (1996)

TAKAISHI,T., T.ONO,and Y.YASUDA: Relationship between muscle fatigue and oxygen uptake during cycle ergometer exercise with different ramp slope

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㧗ᓥ┤அࠊᖹᕝ࿴ᩥ㸸1ศ㛫ࡢ㧗ᙉᗘ㐠ື཯᚟᫬ࡢ࢚ࢿࣝ

ࢠ࣮௦ㅰࡢ᳨ウ㸬ி㒔Ꮫᅬ኱Ꮫ೺ᗣ་⒪Ꮫ㒊⣖せ

3,1-6, 3- 28 (2018)

WALSH M.L. and BANISTER E.W.: The influence of

inspired oxygen on the oxygen uptake response to ramp exercise. Eur.J.Appl.Phyiol. 72:71-75 (1995)

WHIPP,B.J. : The slow component of O

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uptake kinetics during heavy exercise. Med.Sci.Sports Exerc.

26(11):1319-1326 (1994)

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& Neurobiology 153:92-106 (2006)

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26(11):1347-1354 (1994)

YAMAMOTO,M. and H.KANEHISA : Dynamics of anaerobic and aerobic energy supplies during sustained high intensity exercise on cycle ergometer.

Eur.J.Appl.Phyiol. 71:320-325 (1995)

㸦ཎ✏ཷ⌮ᖺ᭶᪥

2018

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10

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11

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