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The patient was a 74-year-old female with a recurrence of invasive breast cancer in the wall of her left chest

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Breast Cancer Recurrence in the Chest Wall Successfully Treated with TS-1

Maya FUKUYO, Yasuteru YOSHINAGA, Yasuko HAGIO and Akinori IWASAKI

Department of Thoracic, Breast endocrine and Pediatric Surgery, Faculty of Medicine, Fukuoka University

Abstract：Both clinical efficacy and the quality of life (QOL) should be taken into consideration when treating eld- erly patients with recurrent breast cancer. The oral combined fluoropyrimidine, TS-1 (tegafur, gimeracil, and oteracil), is a novel anticancer drug. The patient was a 74-year-old female with a recurrence of invasive breast cancer in the wall of her left chest. She had undergone a radical mastectomy 27 years previously to treat left breast cancer. We diag- nosed the recurrence as a triple-negative cancer by core needle biopsy and treated her with 4 courses of oral TS-1 alone, and the tumor clinically disappeared. The only adverse event observed during TS-1 therapy was Grade 2 general fatigue, but there was no decline in the patient's QOL. We therefore consider TS-1 to be a feasible antitumor agent for metastatic or recurrent breast cancer that can prevent a decrease in the QOL, thus making it especially suitable for elderly patients.

Key words： Breast cancer, Recurrence, TS-1, Chest wall tumor, Elderly patient

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