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Serial EEG findings and the Clinical Aspects in patients with Panayiotopoulos and Gastaut Syndrome

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Serial EEG findings and the Clinical Aspects in patients with Panayiotopoulos and Gastaut Syndrome

Sawa   Y

ASUMOTO

, Takahito I

NOUE

, Yukiko I

HARA

, Takeshi K

ANAUMI

, Yuko T

OMONOH

, Takako F

UJITA

, Nobuya N

INOMIYA

, Rie K

ODAMA

, Noriko N

AKAMURA

,

Reimi T

URUSAWA

 and Shinichi H

IROSE

Department of Pediatrics, Faculty of Medicine, Fukuoka University

Abstract:The objective of this study was to evaluate both the EEG findings and the clinical as- pects  of  childhood  occipital  lobe  epilepsy,  Panayiotopoulos(P  type)and  Gastaut(G  type)

syndromes. A total of 30 subjects(P type 26, G type 4)were analyzed regarding their clinical  progress and the sequential EEG changes in the localization of their epileptic foci. 1) onset age,  for  P  type  it  was  4.2 years  while  for  G  type  it  was  8  years. 2)the  age  of  final  seizure  was  5.8  years  for P type, and 12 years for G type  3)the total number of P type seizures was 3 times,  while  G  type  seizures  frequently  occurred  either  daily  or  weekly. Though  treatment  was  not  necessary  for  44% of  the  P  type  patients,  the  G  type  patients  all  received  two  or  more  types  of  medication. In P type cases, the EEG foci in most patients demonstrated shifts in their location  and they became dominant in the frontal area during adolescence. On the other hand, the EEG  foci  in  the  G  type  cases  demonstrated  no  such  shift,  but  instead  tended  to  become  either  hemi- spherical  or  to  demonstrate  secondary  bilateral  synchrony. Moreover,  we  intend  to  study  the  optimal therapies for both types of childhood epilepsy in the future.

Key  words:Panayiotopoulos  syndrome,  Gastaut  Syndrome,  Visual  hallucination,  Auto-        nomic seizure

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