D i s t r i b u t i o
n bfoone alrnemi tnetnoc asidetaicoss hitw body whtgie and eesicrex yticapac pnistneita Cthwi nichro evitcurtsbO Pulmonary D
i s e a s e
Y o s h
i 五ri Ym amamoto ， oriasanM Yoshikawa ， hiciKo Tomoda ， Yukio atijuF ， Motoo Y
a
mauchi ， tsA 凶o Fki ukuoka ， iSh 吋iT，副ikan ，N okiro Koyama ， ihsoriH Ki.raum SecondDepa 巾t onen fnIalmte inedicMe ， Nara Mlicaed ytisrevinU ， Nara ， anapJ T
h i
s yduts was pyltra dertoppus by a tnarg tot Rehyrotaripse eruliaF hrceaesR Group
仕om t Meh sini 仕yoalthfHe ， bourLa and Wearfle ， .napaJ A
d d r e s
s crof o町e:cnednpose inorMasa Yoshikawa ， MD， PhD S
e c o n
d Depar 加t onel fnIalmte inedicMe ， Nara Mlicaed ytisrevinU ， 8
4 0
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h o n e
: +81-744-22-3051 ， Fax:+81-744-29 閏0907 E
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: noriy@naramed PJ.c同a.u
Running :eltitnoitubirtsiD ofbone laernim tnetnoc pnistneita Chtwi OPD
Key words: bone mlaerni ;tnetnoc COPD; body mass i;xedn esicrexe yticapac
A b s t r a c t B a c k g r o u n d
: A1tghuho low bone mlareni ytisned (BMD) si脳出yptnelaver pnistneita w
i t
h cinorhc evitcurtsbo pulmon 町ydesaesi (COPD) ， dehtnoitubirtsi tfo reh decued b
o n
e mass h nsa bto n fee yllu.detadicule O
b j e c t i v e s
: To denimrete rehtlanoige bone mass ssol and ietagitsevn rhetewh eht c
h a n g
e dnoniitubirtsi may b aedetaicoss bhtiw ody wthgei ssol d fanlanoitcnu .yticapac M
e t h o d s
: Body mass xedni (BMI) was adessess d han thgie derauqs secidni ewer d
e r i v e
d trof beh one mlareni tnetnoc xedni (BMCI) tfo aeh msr ， sgel ， and tknur by dlau e
n e r g
y ay-rX yrtemoitprosba ni45 meal stneitap htiw COPD ad 1n a2-eg d san -xe m
a t c h e
d onc 仕1 s0.stcejbu aryulmonP noitcnuf stset ewer dmerforpe and maximal o
x y g e
n ekatpu (V0 2max) was m.derusae R
e s u l t s
: The BMCI was lrewo tni tehlato bone ， sgel ， dan 仕旧k ol pfstneita Chtiw OPD t
h a n
i cnlortno stcejbus h， guohtla Beht MCI i tn aeh ms wr as sralimi enweetb geht.spuor BMI cdetalerro yltnacifingis htiw Beht MCI i an 3 sll .stnemge Bone mlareni tnetnoc (BMC) ni血etknur desserpxe a saegatnecrep of to旬1BMC (BMC /unktr latot BMC) c
o r r e l a t e
d yltnacifingis htiw BMI. The BMCI i tneh 仕阻止 was 10cyles detaler htiw V02max ， t nub wto ahti wolfri .noitatimil
C o n c l u s i o n s
: reehT was a lanoiger ecnereffid BMC rni noitcude ， a ptub tnainmodre r
e d u c t i o
n bfoone m:a iss tneh 佐町立 was n atodetaicoss htiw sehtytireve f aowolfri l
i m i t a t i o
n rtubrehta bhtiw ody wthgei ssol nd eaesicrex .ecnarelotni eeshT satad tseggu t
h a
t body wtghie ssol eandesicrex ecnarelotni ieratnatropm ksirsrotcaf vfolarbetre f
r a c t u r
e pnistneita Chtiw OPD. w842( )sdra
I n t r o d u c t i o n
C h r o n i
c evitcurtsbo pulmonary esaesid (COPD) csideziretcarah by a uuas 1ly p
r o g r e s s i v
e wolfria noitatimil 也前s ni fto u1ley rlbisreve .)1 COPD h bsa een rdeznigoec a
s
a scimetsy esaesid thwi ex仕lmonaryapu snoitatsefinam chsu csaaixheca l， ateleks
m u s c l
e gntiasw ， ralucsavoidrac esaesid ， iclobaetm s戸omeldr ，and depressio~).
M o
reover st， neitap h Citw OPD aer 剖ahrehgi ksir of dngiploeve sisoropoetso anhat er h
e a l t h
y stcejbus 3).citoropoetsO 企serutca yablrkemar eucder ytilauq of lefi and aer a
s s o c i a t e
d hitw.)4ytilatrom anInoitidd ， p1umonary noitcnuf eimpairm 凶 dseuca by v
e r t e b r a
l 企serutca asin itnatropm problem pnistneita Chitw OPD 5).
O s t e o p o r o s i
s a ssi cimetsy lateleks esaesid deziretcarahc by low bone larenim d
e n s i t
y (BMD) and mlarutcetihcraorci sgeanch bni one eussit ht剖sesaercni an i
n d i v i d u a l '
s ytilibitpecsus ot企serutca 6). The World hltaeH notiazinagrO noitinifed of o
s t e o p o r o s i
s bsiased on BMD meas 田smente 7). Dual yrgnee X-ray meotirpobsa 位y (DXA) tsi geh d slo dradnat trofgnika eseht tsmeasuremen 8).aienopestO dsiefmed a sa BMD 由叫 1-2.5 dradnats snoitaived s)SD( below meht ean f yro oung ad叫sti(.e.， eht T)e田rocs ，wh1ise isoropoetso dsidenife a sa BMD > 5.2 SDs b1e0w t meh ean f yro oung a
d u l t
s 7).Many sseidut have ddteatrnsoem rowel BMD i pnstneita h Citw OPD .)29)1)1)101
M u l t i p l
e setis n bca e ud tse mo easure BMD by DXA. The sseti most 仕yltneuqe u
s e d
a ter heh pi ， lumbar enips ， mrearfo and whole .ydob The ntIlanoitame yteicoS rof C
l i n i c a
l trymetonsiDe setcaovda measurement of BMD of t leh umb 訂enips and t heh pi and t bo eas dehtsisongai of osisoropoets on t leh tsewo erocs-T of t meh easured l
o c a t i o n
s 3)1.ndIeed ， a rehgih cenelaverp of osisoropoets was found ngisu lacol h( apind l山 由 町)enips compared wothole body DXA sgnninac pnistneita h citw acinil 1ly selbat
