50
⾲
⾲7 ≟✀య᱁ูࡢᖹᆒᑑࡢẚ㍑࠾ࡼࡧ୍⯡࢘ࣝࢥࢡࢯ᳨ࣥᐃ⤖ᯝ
᭱ᑠ್ ᖺ㱋୰ኸ
್䠄ṓ䠅 ್᭱
㻿 㻣㻜㻜㻝 㻿㻹 㻜㻚㻜㻜㻢 㻖 㻜㻚㻤 㻝㻠㻚㻜 㻞㻠㻚㻜 㻹 㻞㻤㻟㻢 㻹㻸 㻨㻜㻚㻜㻜㻝 㻖 㻜㻚㻜 㻝㻠㻚㻜 㻞㻞㻚㻜 㻸 㻞㻣㻠㻢 㻿㻸 㻨㻜㻚㻜㻜㻝 㻖 㻝㻚㻜 㻝㻞㻚㻜 㻞㻜㻚㻜
Ṛ䚷ஸ䚷䚷䚷䚷ᖺ䚷䚷㱋
య᱁ ㄪᰝ㢌ᩘ 㼃㼕㼘㼏㼛㼤㼚᳨ᐃ䠄㻼
51
⥲ ⥲ᣓ
➨1❶࡛ࡣ, ᒱ㜧┴ෆࡢື≀㝔ࡽ⌮Ꮫᩍᐊ᳨ᰝ౫㢗ࡀ࠶ࡗࡓ8ᖺ㛫ࡢ≟⭘⒆
ࢆᇶ≟✀ู⭘⒆ࡢⓎ⏕≧ἣࢆゎᯒࡋ, ᖹᡂ23ᖺᗘࡢࢾࡢ㣫⫱㢌ᩘㄪᰝࢆẕᩘࡋ
࡚⢒⭘⒆Ⓨ⏕⋡ࢆᚋྥࡁồࡵࡓࠋ≟✀ูࡢⰋᛶ࣭ᝏᛶ⭘⒆ẚ⋡ࡣ, ᑠᆺ≟࡛Ⰻᛶ⭘⒆ࡢ ẚ⋡ࡀ㧗࠸ഴྥࡀㄆࡵࡽࢀࡓࠋ⭘⒆Ⓨ⏕㒊࣭⣔⤫ศ㢮࡛ࡣ, ⓶࠾ࡼࡧ࿘㎶⤌⧊ࡢ⭘⒆ ࡀ᭱ከ࡛ࢦ࣮ࣝࢹࣥࡀከࡃ, ࢲࢵࢡࢫ࣮ࣚࢡࢩࣕࡣᑡ࡞ࡗࡓࠋ⥆࠸࡚, ᾘჾ⣔⭘⒆, ங⭢⭘⒆ࡀከࡃ, ᑠᆺ≟࡛ࡣங⭢⭘⒆ࡢⓎ⏕⋡ࡀ㧗ࡃ, ୰ᆺ࣭ᆺ≟࡛Ⓨ⏕⋡ࡀపࡗࡓࠋ
≟㣫⫱㢌ᩘࡣ, 㞧✀, ࢲࢵࢡࢫ, ᰘ≟, ࣉ࣮ࢻࣝ࠾ࡼࡧࢳ࣡࣡ࡢࡼ࠺ẚ㍑ⓗᑠᆺ≟✀
ࡢேẼࡀ㧗ࡃ, ࣛࣈࣛࢻ࣮ࣝ, ࢦ࣮ࣝࢹࣥ࡞ࡢᆺ≟✀ࡣᑡ࡞࠸ẚ⋡࡞ࡗࡓࠋ≟✀ẖ ࡢ⢒⭘⒆Ⓨ⏕⋡ࡣ, ᰘ≟, ࣉ࣮ࢻࣝ, ࢳ࣡࣡, ࣏࣓ࣛࢽࣥ࠾ࡼࡧ㞧✀࡛ࡣపࡃ, ࣛ
ࣈࣛࢻ࣮ࣝ, ࢥ࣮ࢠ࣮, ࣅ࣮ࢢࣝ, ࢦ࣮ࣝࢹࣥ, ࢩ࢙ࣝࢸ, ࣐ࣝࢳ࣮ࢬ࠾ࡼࡧࣂ࣮
ࢽ࣮ࢬ࡛ࡣ㧗ࡗࡓࠋ⢒ᝏᛶ⭘⒆Ⓨ⏕⋡ࡣ, ᰘ≟, ࣉ࣮ࢻࣝ, ࢳ࣡࣡, 㞧✀࡛ࡣపࡃ,
ࣛࣈࣛࢻ࣮ࣝ, ࢥ࣮ࢠ࣮, ࣅ࣮ࢢࣝ, ࢦ࣮ࣝࢹࣥ, ࢩ࢙ࣝࢸ࠾ࡼࡧࣂ࣮ࢽ࣮ࢬ࡛ࡣ㧗
ࡗࡓࠋ
➨2❶࡛ࡣ, ᒱ㜧┴࡛ࡢ≟⭘⒆Ⓩ㘓ไᗘࢆ❧ࡕୖࡆ, ࢾࡢ⭘⒆Ⓨ⏕⋡ࢆྵࡵࡓ⭘⒆ ࡢⓎ⏕≧ἣࢆ๓ྥࡁㄪᰝศᯒࡋࡓࠋᖹᡂ25ᖺᗘࡢ≟㣫⫱㢌ᩘ㛵ࡍࡿヲ⣽ሗࢆᚓࡿࡓ
ࡵ, ┴ෆ42ᕷ⏫ᮧࣥࢣ࣮ࢺㄪᰝࢆ⾜࠸, ᒱ㜧┴⋇་ᖌᡤᒓࡢື≀㝔ᖹᡂ25 ᖺᗘࡢ⭘⒆Ⓨ⏕ࡢᒆฟ⚊ࡼࡿሗᥦ౪ࢆ౫㢗ࡋࡓࠋᅇࡋࡓᒆฟ⚊ࡢグ㍕ෆᐜࡽ
⭘⒆ࡢᖺ㱋ẚ㍑, ⭘⒆ࡢⰋᛶ࣭ᝏᛶẚ⋡, ⢒⭘⒆Ⓨ⏕⋡࠾ࡼࡧ⢒ᝏᛶ⭘⒆Ⓨ⏕⋡ࢆ⟬
ฟࡋࡓࠋ㣫⫱≟ࡢ≟✀ᵓᡂࡣ, 㞧✀, ࢲࢵࢡࢫ࠾ࡼࡧᰘ≟ࡢ3≟✀࡛㣫⫱≟✀ࡢ⣙༙ᩘࢆ
༨ࡵ, ࣉ࣮ࢻࣝ, ࢳ࣡࣡⥆ࡁ, య᱁ู࡛ࡣ, 㞧✀ࢆ㝖ࡃᑠᆺ≟ࡀ⣙43%, ୰ᆺ≟ࡣ
⣙18%, ᆺ≟ࡣ5%ᮍ‶࡞ࡾ, ᑠᆺ≟ࡢẚ⋡ࡀ㧗ࡗࡓࠋᖺ㱋ᵓᡂࡣ㞤㞝ඹ8ṓࡀ
᭱ከ࡛9ṓ௨ୖ࡛ࡣῶᑡࡋ, 15ṓ௨ୖࡣయࡢ8%࡛࠶ࡗࡓࠋᖹᡂ17ᖺࢆࣆ࣮ࢡࢾ
ࡢ㣫⫱㢌ᩘࡑࡢࡶࡢࡀᖺࠎῶᑡࡋ࡚࠸ࡿᐇែࡀ᫂ࡽ࡞ࡗࡓࠋ≟✀యࡢ⭘⒆Ⓨ⏕ᖹᆒ
52
ᖺ㱋ࡣ10.5ṓ, 㞝10.6ṓ, 㞤10.5ṓ㞤㞝㛫ࡢ᭷ពᕪࡣㄆࡵࡽࢀ࡞ࡗࡓࠋ≟✀య ࡢⰋᛶ⭘⒆ࡢẚ⋡ࡣ47.7%, ࢥ࣮ࢠ࣮, ࣂ࣮ࢽ࣮ࢬ, ࢦ࣮ࣝࢹࣥ࠾ࡼࡧࣛࣈࣛࢻ࣮࡛ࣝ
ࡣ≟✀యࡢẚ⋡ࡼࡾ᭷ព㸦p<0.05㸧ᝏᛶ⭘⒆ࡢẚ⋡ࡀ㧗ࡗࡓࠋ᥎ᐃ⢒⭘⒆Ⓨ⏕⋡࠾
ࡼࡧ᥎ᐃ⢒ᝏᛶ⭘⒆Ⓨ⏕⋡ࡣ, ≟✀య࡛ࡣ1.5%࠾ࡼࡧ0.6%࡛࠶ࡗࡓࠋ
ཌ⏕ປാ┬බ⾲ࡢᒱ㜧┴RV㢌ᩘ㸦Ⓩ㘓㢌ᩘ㸧ࡣ, ᖹᡂ23ᖺᗘ110,434㢌㸦138,939 㢌㸧ᖹᡂ25ᖺᗘ106,752㢌㸦134,783㢌㸧࡛⣙3%ࡢῶᑡࡀㄆࡵࡽࢀ࡚࠸ࡿࠋ➨1❶ࡢ ᖹᡂ23ᖺᗘࡢ㣫⫱㢌ᩘ㸦76,316㢌㸧➨2❶ࡢᖹᡂ25ᖺᗘࡢ㣫⫱㢌ᩘ㸦83,204㢌㸧ࢆ
ẚ㍑ࡍࡿᖹᡂ25ᖺᗘࡢ᪉ࡀ⣙9%ቑຍࡋ࡚࠸ࡿࡀ, ࡇࢀࡣ, ༠ຊࢆ౫㢗ࡋࡓᕷ⏫ᮧ
ࡽࡢࣥࢣ࣮ࢺᅇ⋡ࡀྥୖࡋࡓࡓࡵ࡛, 㣫⫱㢌ᩘࡀቑຍࡋࡓࡇ࡛ࡣ࡞࠸⪃࠼࡚࠸
ࡿࠋ୍᪉࡛, ≟✀ẖࡢ㣫⫱ẚ⋡ࡣㄪᰝᖺᗘࡼࡿኚືᖜࡣ2%ᮍ‶࡛࠶ࡾ, 㣫⫱⋡ࡢࡁ
࡞ኚືࡣㄆࡵࡽࢀࡎ, ࣥࢣ࣮ࢺᅇ⋡ࡢᙳ㡪ࢆཷࡅࡃ࠸⪃࠼ࡿࠋ
⭘⒆デ᩿⥲ᩘࡣ, ᖹᡂ23ᖺᗘᖹᡂ25ᖺᗘࡁ࡞㐪࠸ࡣ࡞ࡗࡓࡶࡢࡢ, ≟✀ู
ࡢデ᩿ᩘ࡛ࡣࡁ࡞ᕪࡀ⏕ࡌࡓࠋ⭘⒆ࡢ㞟✚᪉ἲࡀ␗࡞ࡿࡓࡵྠ୍ᇶ‽࡛ẚ㍑ࡣ࡛
ࡁ࡞࠸ࡀ, ேẼ≟✀ࡢ㣫⫱㢌ᩘࡢኚືࡶࡋࡃࡣᖺ㱋ศᕸࡼࡿᙳ㡪ࡀ⪃࠼ࡽࢀࡿࠋJKCබ
⾲ࡢࢹ࣮ࢱ࡛ࡣ, ከࡃࡢ≟✀࡛Ⓩ㘓㢌ᩘࡀῶᑡࡋ࡚࠸ࡿ୰࡛ࢲࢵࢡࢫ, ࣉ࣮ࢻࣝ࠾ࡼࡧ ࢳ࣡࣡࡞≉ᐃࡢᮇᛴቑࡋࡓ≟✀ࡀ࠶ࡿࡓࡵ㸪≉ᐃࡢ≟✀ࡢὶ⾜ᖺ㱋ศᕸࡢ᥎⛣
ࡼࡾ⭘⒆ዲⓎ≟✀ࡀኚࡋ, ⭘⒆Ⓨ⏕ᩘࡀከ࠸ࡓࡵᏳ᫆ዲⓎ≟✀᥎ ࡋ࡚ࡋࡲ࠺
༴㝤ᛶࡀ⪃࠼ࡽࢀࡿࠋ
⭘⒆デ᩿ࡢᙳ㡪࡛⭘⒆Ⓨ⏕⋡ࡶഹ࡞ኚືࡀㄆࡵࡽࢀࡓࠋከࡃࡢ≟✀࡛ࡣኚືᖜࡀ1%
ᮍ‶࡛࠶ࡾ, 㣫⫱㢌ᩘ࠾ࡼࡧ⭘⒆ᩘࡢቑῶࡢᙳ㡪⪃࠼ࡽࢀࡿࡀ, ࢲࢵࢡࢫ, ࢦ࣮
ࣝࢹࣥ࠾ࡼࡧࣃࢢࡢࡳኚືᖜࡀ1%௨ୖ࡞ࡗࡓࠋࢦ࣮ࣝࢹ࡛ࣥࡣ㣫⫱⋡⭘⒆ᩘࡀඹ
ῶᑡࡋ࡚࠸ࡿࡇࡽ⭘⒆ዲⓎᖺ㱋ࢆ㐣ࡂࡓࡓࡵ⪃࠼ࡽࢀࡿࠋࢲࢵࢡࢫࡣ, Ⓨ⏕⋡ࡀ పࡗࡓࡶ㛵ࢃࡽࡎഹ2ᖺ࡛㧗ࡃ࡞ࡗ࡚࠾ࡾ, ⭘⒆ዲⓎᖺ㱋ࡢࢾࡀቑຍࡋࡓྍ⬟ᛶ ࡀ࠶ࡾᚋࡢືྥࢆほᐹࡍࡿᚲせࡀ࠶ࡿ⪃࠼ࡿࠋࣃࢢࡘ࠸࡚ࡣ, Ⓩ㘓ᩘ, 㣫⫱⋡࠾ࡼ
ࡧ⭘⒆ᩘඹኚࡀ࡞࠸ࡶ㛵ࢃࡽࡎⓎ⏕⋡ࡀቑຍࡋࡓཎᅉࡣ࡛᫂࠶ࡾ, ⥅⥆ㄪ
53
ᰝࢆࡍࡿᚲせࡀ࠶ࡿ⪃࠼ࡿࠋ」ᩘᖺᗘࡢㄪᰝࡼࡾ, ≉ᐃࡢ≟✀࡛⢒⭘⒆Ⓨ⏕⋡ࡢኚື
ࡀㄆࡵࡽࢀࡓࡇࡼࡾ, ⭘⒆ዲⓎᖺ㱋ࢆᖹᆒᑑ㛵㐃ࡅ࡚⪃࠼ࡿᚲせᛶࡀ᫂ࡽ
࡞ࡗࡓࠋ
➨1❶࠾ࡼࡧ➨2❶ࡢ⤖ᯝࡽ, ≟✀ẖࡢᖺ㱋ศᕸ, ≟✀ẖࡢᖹᆒᑑ➼ࡢ㐪࠸ࡼࡿ
⭘⒆Ⓨ⏕ᖺ㱋ࡢ㐪࠸࡞ࡀ᪂ࡓ࡞᳨ウㄢ㢟࡞ࡗࡓࠋ➨3❶࡛ࡣ, ⊂⮬ྡྂᒇᕷࡢᩪሙ ࡢ༠ຊࢆᚓ࡚㣫⫱≟ࡢ≟✀ẖࡢṚஸᖺ㱋ࢆㄪᰝࡋ, ≟✀ẖࡢ⏕Ꮡ᭤⥺ᖹᆒᑑ㸦ᖺ㱋୰
ኸ್㸧ࢆ⟬ฟࡍࡿࡇࡼࡾ, ≟✀ẖࡢ⭘⒆Ⓨ⏕ᖺ㱋ࡢ㛵㐃ࢆศᯒࡋࡓࠋ64ᖺ
ࡽᖹᡂ5ᖺࡢ5ᖺ㛫ㄌ⏕ࡋࡓᛮࢃࢀࡿ17,786㢌ศࡢࢹ࣮ࢱࢆ⏝࠸࡚⏕Ꮡ᭤⥺ᖹᆒᑑ
㸦ᖺ㱋୰ኸ್㸧ࢆ⟬ฟࡋࡓࠋ≟✀య࠾ࡼࡧ≟✀ẖࡢ⏕Ꮡศᯒࢆ⾜ࡗࡓ⤖ᯝ, ᰘ≟, ࢲ
ࢵࢡࢫ, ࣮ࣚࢡࢩࣕ, ࣉ࣮ࢻࣝ࠾ࡼࡧ㞧✀ࡢ5≟✀ࡣ᭷ព(p<0.05)⏕Ꮡ㛫ࡀ㛗࠸ഴྥ
ࢆ♧ࡋ, ࣅ࣮ࢢࣝ, ࢩࣗࢼ࢘ࢨ࣮, ⛅⏣≟, ࣃࢢ, ࢩ࢙ࣝࢸ, ࢦ࣮ࣝࢹࣥ, ࢟ࣕࣂ
ࣜ, ࢩ࣭࣋ࣜࣥࣁࢫ࣮࢟, ࢪ࣮࣐࣭ࣕࣥࢩ࢙ࣃ࣮ࢻ, ࢢ࣮ࣞࢺ࣭ࣆࣞࢽ࣮ࢬ,࠾ࡼࡧ ࡑࡢࡢ11≟✀ࡣ᭷ព(p<0.05)⏕Ꮡ㛫ࡀ▷࠸ഴྥࢆ♧ࡋࡓࠋయ᱁ูࡢ⤖ᯝࡣ, ᑠᆺ≟
୰ᆺ≟ࡣࡶᖺ㱋୰ኸ್ࡀྠࡌ࡛⏕Ꮡ᭤⥺ࡢ㌶㊧ࡀ㏆ఝ࡞ࡗࡓࡀ, ᆺ≟ࡢࡳᖺ 㱋୰ኸ್ࡶపࡃ, ᫂ࡽୗഃࡢ㌶㊧ࢆᥥࡁ᭷ព (p<0.05) Ṛஸᖺ㱋ࡀప࠸ഴྥࢆ♧
ࡋࡓࠋ
≟✀ẖ࠾ࡼࡧయ᱁ูࡢ⏕Ꮡศᯒ⤖ᯝࡼࡾ, ᑠᆺ≟୰ᆺ≟ࡣࡶᖺ㱋୰ኸ್ࡀྠ
ࡌ࡛⏕Ꮡ᭤⥺ࡢ㌶㊧ࡀ㏆ఝ࡞ࡗࡓࡀ, ᆺ≟ࡢࡳᖺ㱋୰ኸ್ࡶపࡃ, ᫂ࡽୗഃࡢ
㌶㊧ࢆᥥࡁ᭷ព (p<0.05) Ṛஸᖺ㱋ࡀప࠸ഴྥࢆ♧ࡋࡓࠋᅇࡢ⏕Ꮡศᯒ࡛ࡣ, Ṛஸ ཎᅉࡢศᯒࡣᐇࡋ࡚࠸࡞࠸ࡀ, ⱥᅜ࡛ࡢㄪᰝ⤖ᯝ(2)ࡼࡿ, ≟✀యࡢṚஸཎᅉࡢ 27%㸦ᖹᆒ㸧ࡀᝏᛶ⭘⒆ࡼࡿࡶࡢ࡛࠶ࡾ, ࢥ࣮ࢠ࣮ , ࣅ࣮ࢢࣝ, ࣇࣞࣥࢳ, ࢦ࣮ࣝࢹ
ࣥ, ࣛࣈࣛࢻ࣮ࣝ࠾ࡼࡧࣂ࣮ࢽ࣮ࢬ࡞ࡣᝏᛶ⭘⒆ࡼࡿṚஸཎᅉࡀ28.4%㹼45.7%ᝏ ᛶ⭘⒆ࡢࣁࣜࢫࢡ≟✀࡛࠶ࡿࡇࡀ᫂ࡽ࡞ࡗ࡚࠸ࡿࠋྠᵝ, ᮏ◊✲⤖ᯝࡽࡶᑠ ᆺ࣭୰ᆺ≟ẚᆺ≟࡛ࡣᝏᛶ⭘⒆ẚ⋡ࡀ㧗࠸ഴྥࢆ♧ࡋ࡚࠾ࡾ, Ṛஸཎᅉ⧅ࡀࡿ
⪃࠼ࡽࢀࡿࠋᾏእࡢㄪᰝ⤖ᯝࡣ, ᮏ◊✲ࡣ≟✀ࡀ␗࡞ࡾᆺ≟✀ࡀከࡃࡢẚ⋡ࢆ༨ࡵ࡚
54
࠸ࡿࡀ, ᑠᆺ≟✀࡛ࡣࢩ࣮ࢬ࣮ , ࢲࢵࢡࢫࡶྵࡲࢀ࡚࠾ࡾ, ࡇࡢ≟✀ࡢṚஸཎᅉࡋ
࡚ࡢᝏᛶ⭘⒆ẚ⋡ࡣ14.5%㹼16.7%ࡢ≟✀ࡼࡾ᫂ࡽప࠸ (2) ࠋᮏ◊✲⤖ᯝࡽࡶ
⭘⒆Ⓨ⏕⋡ࡣᑠᆺ≟࡛పࡃ, ᆺ≟࡛㧗࠸ഴྥࡀ࠶ࡿࡇࢆࡅ࡚࠾ࡾ≟✀ᵓᡂࢆ⪃
៖ࡋࡓ⭘⒆Ⓨ⏕⋡ࡢㄪᰝࡢ㔜せᛶࢆㄆ㆑ࡍࡿࡇࡀ࡛ࡁࡓࠋ
ᅇ, ᫂ࡽ࡞ࡗࡓ⭘⒆Ⓨ⏕ᖹᆒᖺ㱋ࡣ, 10.4ṓࡽ10.5ṓ࡛࠶ࡿࡀ, ≟✀ẖࡢ⭘
⒆Ⓨ⏕ᖺ㱋ᖹᆒᑑࡢ┦㛵ࡣㄆࡵࡽࢀ࡞ࡗࡓࠋ⫧‶⣽⬊⭘ࡢ᭱ከᖺ㱋ࡣ6.1ṓࡽ8.0 ṓ (24) , ங⭢⭘⒆ࡢయ᱁ูᖺ㱋ศᕸࡣᑠᆺ≟9.53s2.98ṓ, ୰ᆺ≟9.39s2.98ṓ,
ᆺ≟9.07s2.67ṓ࡞ࡢሗ࿌ (44) ࡀ࠶ࡿࠋ୍᪉, 㦵⭘⒆㛵ࡋ࡚ࡣ, Ⓨ⏕ᖺ㱋ࡢ୰ኸ
್ࡀࣜࢵࢩ࣭ࣗ࢘ࣝࣇࣁ࢘ࣥࢻ5.5ṓ, ࣮ࣞ࢜ࣥ࣋ࣝ࢞7.2ṓ, ࢽ࣮ࣗࣇࣥࢻࣛࣥ
ࢻ8.8ṓ, ࣛࣈࣛࢻ࣮ࣝ11.6ṓ≟✀ᖺ㱋ᕪࢆㄆࡵࡿሗ࿌ (4) ࡶ࠶ࡿࠋᾏእࡢሗ࿌࡛
ࡣ, ⭘⒆Ⓨ⏕ᖺ㱋ࡔࡅ࡛࡞ࡃᖹᆒᑑ㸦Ṛஸ୰ኸ್㸧ࡶᮏ◊✲ࡢࢹ࣮ࢱࡣ࠸ࡃࡘ␗
࡞ࡗ࡚࠾ࡾ (2, 36) , ≟✀ࡸయ᱁ࡔࡅ࡛࡞ࡃ, Ⓨ⏕⭘⒆ࡢ✀㢮ࡸ㣫⫱⎔ቃ࡞ࡢせᅉ࡞
ࡶ⪃៖ࡋ᳨࡚ドࡍࡿᚲせࡀ࠶ࡿ⪃࠼ࡿࠋ
⌧ᅾࡢ㣫⫱≟ࡢᖺ㱋ᵓᡂࡣ㞤㞝ඹ8ṓࡽ9ṓࡀࣆ࣮ࢡ࡛࠶ࡾᚋࡣ㧗㱋క࠸
㣫⫱㢌ᩘࡢῶᑡࡀᠱᛕࡉࢀ࡚࠸ࡿࠋ⌧Ⅼ࡛ࡣ15ṓ௨ୖࡢ㣫⫱≟ࡣయࡢ8%࡛࠶ࡿࡀ
ᚋࡣὶ⾜ࡢ≟✀ࡢኚࡸ㣫⫱⎔ቃ་⒪࣭ᝈண㜵ᢏ⾡ࡢ㐍Ṍࡼࡾࢾࡢᖹᆒᑑࡸ
ᖺ㱋ᵓᡂࡀኚࡍࡿ⪃࠼ࡽࢀࡿࠋ⢒⭘⒆Ⓨ⏕⋡ࡢㄪᰝ࠾ࡼࡧ㣫⫱≟ࡢṚஸᖺ㱋ㄪᰝࢆ⾜
ࡗࡓ⤖ᯝ, ୍⯡ⓗබ⾲ࡉࢀࡓࡾ, ⾜ᨻ➼ಖ⟶ࡉࢀࡓࡾࡋ࡚࠸ࡿධᡭྍ⬟࡞ࢹ࣮ࢱࡔ ࡅ࡛ࡣṇ☜࡞⭘⒆Ⓨ⏕⋡ࡢ⟬ฟࡣᅔ㞴࡛࠶ࡿ⪃࠼ࡿࠋᅇࡢࡼ࠺࡞ㄪᰝࡣ, ᚋࡢ EBVM (Evidence Based Veterinary Medicine) ᚲࡎᚲせ࡞ࡿ⪃࠼ࡿࠋᾏእࢹ࣮ࢱࡔ ࡅ࡛ࡣ༑ศ࡛࠶ࡿࡓࡵ, ᡃᅜ⊂⮬ࡢࢹ࣮ࢱࡣࢾࡀࢇᑐ⟇㔜せ࡛࠶ࡿࠋ㣫⫱≟ࡢ㣫⫱
≧ἣࡢࢹ࣮ࢱࡔࡅ࡛ࡣ࡞ࡃ, ᑗ᮶ⓗࡣᝈࡢࢹ࣮ࢱࡸ⒪᪉ἲ⤒㐣࡞ࡶࢹ࣮ࢱ࣋
࣮ࢫࡍࡿࡇ࡛, ⒪ࡢ࢚ࣅࢹࣥࢫࢆ✚ࡳୖࡆࡿࡇࡀ࡛ࡁᚋࡢ⒪᪉㔪ࢆ᳨ウࡍ
ࡿୖ࡛ࡢཧ⪃࡞ࡿ⪃࠼ࡿࠋ
55
ㅰ ㅰ㎡
ᮏ✏ࢆ⤊࠼ࡿ࠶ࡓࡾ, ࡈᣦᑟࡈ㠴᧡ࢆ㈷ࡾࡲࡋࡓᮏ◊✲⛉ࡢᑿᖾႹᩍᤵ, ᳃ᓫ ᩍᤵ῝⏒ࡢㅰពࢆ⾲ࡋࡲࡍࠋㄽᩥࡢᰯ㜀ࡈຓゝࢆ㈷ࡾࡲࡋࡓᮏ◊✲⛉⋇་⌮Ꮫ◊✲
ᐊࡢᰗᚨ☻ᩍᤵ, 㓇ὒᶞᩍᤵ㸪ᮾி㎰ᕤᏛ⋇་⮫ᗋ⌮Ꮫ◊✲ᐊࡢ⏫⏣Ⓩᩍᤵ, ᖏᗈ␆⏘Ꮫ⮫ᗋ⋇་Ꮫ◊✲㒊㛛కື≀⋇་⒪ศ㔝ࡢᐑཎ㑻ᩍᤵ, ᒾᡭᏛ⋇་እ
⛉Ꮫ◊✲ᐊࡢᏱሯ㞝ḟᩍᤵ῝ㅰ࠸ࡓࡋࡲࡍࠋ
≟⭘⒆Ⓩ㘓ไᗘࡈ༠ຊࢆ࠸ࡓࡔ࠸ࡓᒱ㜧┴⋇་ᖌ࠾ࡼࡧ㛤ᴗື≀㝔ࡢඛ⏕᪉῝
ㅰࡍࡿࡶ, ḟᖺᗘ௨㝆ࡶࡼࡾ୍ᒙࡢࡈ༠ຊࢆ࠸ࡓࡔࡅࡿࡼ࠺㔜ࡡ࡚࠾㢪࠸⏦ࡋୖ
ࡆࡲࡍࠋᏛⓗ࡞⤫ィ࣭ゎᯒᡭἲ㛵ࡋ࡚, ࡈᣦᑟ࠸ࡓࡔ࠸ࡓᮾி㎰ᕤᏛ⋇་බ⾗⾨⏕
Ꮫ◊✲ᐊࡢᯘ㇂⚽ᶞᩍᤵ࠾ࡼࡧື≀⾨⏕◊✲ᡤࡢᒣᮏஂ༤ኈ῝ㅰ࠸ࡓࡋࡲࡍࠋ㣫⫱
≟ࡢ㣫⫱㢌ᩘࣥࢣ࣮ࢺ࠾ࡼࡧ⭘⒆Ⓩ㘓ࢹ࣮ࢱࡢ㞟✚ࢆ࠾ᡭఏ࠸࠸ࡓࡔ࠸ࡓᒱ㜧Ꮫ⋇་
ศᏊែᏛ◊✲ᐊࡢᆏ⏣᫂⨾ࡉࢇឤㅰ࠸ࡓࡋࡲࡍࠋ
ࡲࡓ, ㈗㔜࡞✚ࢹ࣮ࢱࢆᥦ౪࠸ࡓࡔ࠸ࡓ, ᐀ᩍἲே࣭㛗ᴦᑎື≀㟋ᅬࡢஂ႐Ύእఫ⫋
࠾ࡼࡧ㟋ᅬ㛵ಀ⪅ࡢⓙᵝ῝ㅰ࠸ࡓࡋࡲࡍࠋ
56
せ せ᪨
㏆ᖺ, ⏕ά⎔ቃࡸឤᰁண㜵ࡢ㐍Ṍࡼࡾ㣫⫱≟ࡢᑑࡀᘏࡧࡓࡇక࠸, ⭘⒆ᛶ
ᝈࡢⓎ⏕ࡶከࡃ࡞ࡗ࡚ࡁࡓࠋࣄࢺ࡛ࡣ, ᅜໃㄪᰝ࡞ࡢᇶ♏ࢹ࣮ࢱࢆᇶྛ✀ᝈࡢ
Ꮫ◊✲࡞ࡀ㐍ࢇ࡛࠾ࡾ, ࣄࢺࡢࡀࢇⓏ㘓ࡶࡀࢇண㜵ࢆࡍࡿୖ࡛㔜せ࡞ᙺࢆᢸࡗ࡚࠸
ࡿࡀ, ᡃᅜ࠾ࡅࡿࢾࡢࡀࢇⓎ⏕≧ἣ㛵ࡋ࡚ࡣ, ≟✀ูࡢヲ⣽࡞ሗ࿌ࡣぢᙜࡓࡽࡎ,
≟✀ูࡢ⭘⒆Ⓨ⏕⋡ࡶ᫂ࡽ࡛ࡣ࡞࠸ࠋࡑࡢ⌮⏤ࡋ࡚ࡣ, ᪥ᮏᅜෆ࡛ࡣࢾࡢఫẸ⚊ࡸ
ᡞ⡠ࡀᏑᅾࡋ࡞࠸ࡓࡵ, ṇ☜࡞㣫⫱㢌ᩘࡀࢃࡗ࡚࠸࡞࠸Ⅼ࠶ࡿࠋṇ☜࡞㣫⫱㢌ᩘࡀᢕ ᥱ࡛ࡁ࡞ࡅࢀࡤ, ṇ☜࡞Ꮫⓗㄪᰝࡢ⤖ᯝࢆᐈほⓗホ౯ࡍࡿࡇࡣᅔ㞴࡛࠶ࡾ, క
ື≀࡛࠶ࡿࢾࡢຠᯝⓗ࡞ࡀࢇᑐ⟇ࢆᐇࡍࡿୖ࡛ࡢࡁ࡞㞀ᐖ࡞ࡿࠋ
ࡑࡇ࡛, ➨1❶࡛ࡣ, ᒱ㜧Ꮫ⋇་⌮Ꮫᩍᐊデ᳨᩿ᰝ౫㢗ࡢ࠶ࡗࡓ8ᖺ㛫ࡢ≟⭘⒆
ࢆᇶ≟✀ẖࡢ⭘⒆ูⓎ⏕≧ἣࢆᚋྥࡁㄪᰝศᯒࡋ, ᒱ㜧┴ୗ࠾ࡅࡿᖹᡂ23ᖺ ᗘࡢࢾࡢ㣫⫱≧ἣㄪᰝࡽ≟✀ูࡢ⢒⭘⒆Ⓨ⏕⋡ࢆồࡵࡓࠋ⭘⒆Ⓨ⏕ᖺ㱋ࢆゎᯒࡋࡓ
ࡇࢁ, 㞝࡛ࡣ10.4±2.98ṓ, 㞤࡛ࡣ10.4±2.83ṓ࡞ࡾ㞤㞝࡛ࡢ᭷ពᕪࡣ࡞ࡗࡓࠋ≟✀
యࡢᝏᛶ⭘⒆ࡢẚ⋡ࡣ57.5%࡞ࡾ, ≟✀ูⰋᛶ࣭ᝏᛶ⭘⒆ࡢẚ⋡ࢆศᯒࡍࡿ, ᑠᆺ
≟࡛Ⰻᛶ⭘⒆ࡢẚ⋡ࡀ㧗࠸ഴྥࡀㄆࡵࡽࢀࡓࠋ⭘⒆Ⓨ⏕㒊ࡣከ࠸㡰⓶⣔24.4%, ᾘ
ჾ⣔18.1%, ங⭢⭘⒆17.8%࡞ࡾ, ≉ᑠᆺ≟࡛ࡣங⭢⭘⒆ࡢⓎ⏕⋡ࡀ㧗࠸ഴྥࡀ
ぢࡽࢀࡓࠋࡲࡓ, ≟✀ẖࡢ⢒⭘⒆Ⓨ⏕⋡ࢆồࡵࡓ⤖ᯝ, ࢲࢵࢡࢫ:0.7%, ᰘ≟:0.5%, ࣉ
࣮ࢻࣝ:0.2%, ࢳ࣡࣡:0.3%, ࣏࣓ࣛࢽࣥ:0.1%࠾ࡼࡧ㞧✀:0.6%ࡣపࡃ㸦p<0.05㸧, ࣛ
ࣈࣛࢻ࣮ࣝ:2.6%, ࢩ࣮ࢬ࣮:1.5%, ࢥ࣮ࢠ࣮:3.0%, ࣃࣆࣚࣥ:1.3%, ࣅ࣮ࢢࣝ:2.3%,
࣮ࣚࢡࢩࣕ:1.5%, ࢦ࣮ࣝࢹࣥ:4.3%, ࢩࣗࢼ࢘ࢨ࣮:1.5%, ࢩ࢙ࣝࢸ:2.5%, ࣐ࣝࢳ࣮
ࢬ:2.0%, ࣃࢢ:2.1%࠾ࡼࡧࣂ࣮ࢽ࣮ࢬ:7.9%ࡣ㧗࠸⤖ᯝ࡞ࡗࡓ㸦p<0.05㸧ࠋྠᵝ⢒ᝏ ᛶ⭘⒆Ⓨ⏕⋡ࡣ, ᰘ≟: 0.3%, ࣉ࣮ࢻࣝ: 0.0%, ࢳ࣡࣡: 0.2%, ࣏࣓ࣛࢽࣥ: 0.1%࠾ࡼ
ࡧ㞧✀: 0.4%ࡣపࡃ㸦p<0.05㸧, ࣛࣈࣛࢻ࣮ࣝ: 1.9%, ࢥ࣮ࢠ࣮: 2.1%, ࣅ࣮ࢢࣝ: 1.8%,
57
ࢦ࣮ࣝࢹࣥ: 2.8%, ࢩ࢙ࣝࢸ: 1.7%, ࠾ࡼࡧࣂ࣮ࢽ࣮ࢬ: 6.4%ࡣ㧗࠸⤖ᯝ࡞ࡗࡓ 㸦p<0.05㸧ࠋ
➨2❶࡛ࡣ, 㣫⫱≟ࡢ⭘⒆Ꮫ◊✲ࡢ➨୍Ṍࡋ࡚, ᒱ㜧┴࡛ࡢ≟⭘⒆Ⓩ㘓ไᗘࢆ❧
ࡕୖࡆ, ࢾࡢ⢒⭘⒆Ⓨ⏕⋡ࢆྵࡵࡓ⭘⒆ࡢⓎ⏕≧ἣࢆ๓ྥࡁㄪᰝศᯒࡋࡓࠋᒱ㜧┴ෆ ࡢື≀㝔ࡢ33.6%ࡽ⭘⒆ࡢᒆฟࡀ࠶ࡾ, ☜ᐃデ᩿ࡋࡓ670㢌࡛ゎᯒࢆ⾜ࡗࡓࠋ┴ෆࡢ 㣫⫱㢌ᩘ⭘⒆ᩘࢆ⿵ṇࡋ, ≟✀ẖࡢ⢒㸦ᝏᛶ㸧⭘⒆Ⓨ⏕⋡ࢆ⟬ฟࡋࡓࠋ㣫⫱≟ࡢ≟
✀ᵓᡂࡣ, 㞧✀㸸22.6%, ࢲࢵࢡࢫ㸸13.5%࠾ࡼࡧᰘ≟㸸12.2%ࡢ3≟✀࡛㣫⫱≟✀ࡢ⣙༙
ᩘࢆ༨ࡵ, ᖺ㱋ᵓᡂࡣ㞤㞝ඹ8ṓࢆࣆ࣮ࢡࡋ, 9ṓࢆ㐣ࡂࡿ㡭ࡽῶᑡࡋጞࡵ, 15 ṓ௨ୖࡢ㣫⫱≟ࡣయࡢ8%࡛࠶ࡾ, 㣫⫱≟ࡢᖹᆒᖺ㱋ࡣ8.39ṓ࡛㞤㞝ඹྠࡌ࡛࠶ࡗࡓࠋ
≟✀యࡢ⢒㸦ᝏᛶ㸧⭘⒆Ⓨ⏕⋡ࡣ2.6%㸦1.0%㸧࡞ࡗࡓࠋ⢒㸦ᝏᛶ㸧⭘⒆Ⓨ⏕⋡ࡀ᭷ព 㸦p<0.05㸧㧗࠸≟✀ࡣ, ࢩ࣮ࢬ࣮㸸4.2%, ࢲࢵࢡࢫ㸸4.3%㸦2.2%㸧, ࣃࢢ㸸7.9%㸦3.5%㸧, ࢥ࣮ࢠ࣮㸸5.6%㸦3.7%㸧, ࣇࣞࣥࢳ㸸5.5%, ࣅ࣮ࢢࣝ㸸3.8%㸦2.4%㸧, ࣂ࣮ࢽ࣮ࢬ㸸13.1%
㸦11.5%㸧, ࢦ࣮ࣝࢹࣥ㸸5.1%㸦4.0%㸧࠾ࡼࡧࣛࣈࣛࢻ࣮ࣝ㸸5.7%㸦4.1%㸧࡛࠶ࡗࡓࠋⓎ
⏕⋡ࡀప࠸≟✀ࡣࢳ࣡࣡㸸0.9%㸦0.5%㸧ࣉ࣮ࢻࣝ㸸1.9%࠾ࡼࡧᰘ≟㸸1.1%㸦0.4%㸧࡛࠶
ࡾ, ᆺ≟࡛ࡣ⢒㸦ᝏᛶ㸧⭘⒆Ⓨ⏕⋡ࡀ㧗࠸ഴྥࡀࡳࡽࢀࡓࠋ
➨3❶࡛ࡣ, Ꮫ◊✲ࡸ⭘⒆ண㜵◊✲ࡢ㊊ࡾࡋ࡚ྡྂᒇᕷࡢᩪሙࡢ༠ຊࢆᚓ࡚㣫
⫱≟ࡢ≟✀ẖࡢṚஸᖺ㱋ࡽ, ≟✀ẖ࠾ࡼࡧయ᱁ูࡢᖹᆒᑑ㸦ᖺ㱋୰ኸ್㸧ࢆ⟬ฟࡋࡓࠋ
60ᖺࡽᖹᡂ25ᖺࡢ㣫⫱≟ࡢⅆⴿグ㘓81,065㢌ࡽ≟✀࠾ࡼࡧṚஸᖺ㱋Ṛஸ᪥
ࡀ᫂ࡽ࡞ࡶࡢࡢࡳࢆᢳฟࡋ, 64ᖺࡽᖹᡂ5ᖺࡢ5ᖺ㛫ㄌ⏕ࡋࡓ17,786㢌ศࡢ ࢹ࣮ࢱࢆ⏝࠸࡚ゎᯒࢆ⾜࠸, ᪥ᖖࡢ⮫ᗋ⌧ሙ࡛ゝࢃࢀ࡚࠸ࡿࠕᑠᆺ≟ࡣᑑࡀ㛗ࡃ, ᆺ
≟ࡣᑑࡀ▷࠸ࠋࠖࡇࡢ᰿ᣐ࡞ࡿࡼ࠺࡞㣫⫱≟ࡢᖹᆒᑑࡢᣦᶆࢆㄪᰝࡋࡓࠋ≟✀
య࠾ࡼࡧ≟✀ẖࡢ⏕Ꮡศᯒࢆ⾜ࡗࡓ⤖ᯝ, ≟✀యࡢᖺ㱋୰ኸ್ࡣ13.0ṓ࡞ࡾ, ᰘ
≟㸸15.0ṓ, ࢲࢵࢡࢫ㸸15.0ṓ, ࣮ࣚࢡࢩࣕ㸸14.0ṓ, ࣉ࣮ࢻࣝ㸸14.0ṓ࠾ࡼࡧ㞧✀㸸 14.0ṓࡢ5≟✀ࡣ᭷ព(p<0.05)Ṛஸᖺ㱋ࡀ㧗࠸ഴྥࢆ♧ࡋ, ࣅ࣮ࢢࣝ㸸13.0ṓ, ࢩࣗ
ࢼ࢘ࢨ࣮㸸12.3ṓ, ⛅⏣≟㸸13.0ṓ, ࣃࢢ㸸13.0ṓ, ࢩ࢙ࣝࢸ㸸12.0ṓ, ࢦ࣮ࣝࢹࣥ㸸
58
12.0ṓ, ࢟ࣕࣂࣜ㸸12.0ṓ, ࢩ࣭࣋ࣜࣥࣁࢫ࣮࢟㸸12.0ṓ, ࢪ࣮࣐࣭ࣕࣥࢩ࢙ࣃ࣮
ࢻ㸸11.0ṓ, ࢢ࣮ࣞࢺ࣭ࣆࣞࢽ࣮ࢬ㸸11.0ṓ࠾ࡼࡧࡑࡢ㸸12.0ṓࡢ11≟✀ࡣ᭷ព(p<0.05)
Ṛஸᖺ㱋ࡀప࠸ഴྥࢆ♧ࡋࡓࠋయ᱁ูࡢ⤖ᯝࡣ, ᑠᆺ≟୰ᆺ≟ࡣࡶᖺ㱋୰ኸ್
ࡀྠࡌ࡛⏕Ꮡ᭤⥺ࡢ㌶㊧ࡀ㏆ఝ࡞ࡗࡓࡀ, ᆺ≟ࡢࡳᖺ㱋୰ኸ್ࡶపࡃ, ᫂ࡽୗ
ഃࡢ㌶㊧ࢆᥥࡁ᭷ព(p<0.05)Ṛஸᖺ㱋ࡀప࠸ഴྥࢆ♧ࡋࡓࠋ⭘⒆Ⓨ⏕ᖹᆒᖺ㱋ࡣ, 10.4 ṓࡽ10.5ṓ࡛࠶ࡿࡀ, ≟✀ẖࡢ⭘⒆Ⓨ⏕ᖺ㱋࠾ࡼࡧᖹᆒᑑࡢ┦㛵ࡣㄆࡵࡽࢀ࡞ࡗ ࡓࡓࡵ, ≟✀ࡸయ᱁ࡔࡅ࡛࡞ࡃ, Ⓨ⏕⭘⒆ࡢ✀㢮ࡸ㣫⫱⎔ቃ࡞ࡢせᅉ࡞ࡶ⪃៖ࡋ࡚
᳨ドࡍࡿᚲせࡀ࠶ࡿ⪃࠼ࡿࠋ
ᅇ⾜ࡗࡓㄪᰝ◊✲ࡣ, ᚋࡢEBVM (Evidence Based Veterinary Medicine) ᭷⏝
࡞ࡿ⪃࠼ࡿࠋᾏእࢹ࣮ࢱࡔࡅ࡛ࡣ༑ศ࡛࠶ࡾ, ᡃࡀᅜ⊂⮬ࡢࢹ࣮ࢱࡣࢾࡀࢇᑐ⟇
㔜せ࡛࠶ࡿࠋ㣫⫱≟ࡢ㣫⫱≧ἣࡢࢹ࣮ࢱࡔࡅ࡛ࡣ࡞ࡃ, ᑗ᮶ⓗࡣᝈࡢࢹ࣮ࢱࡸ⒪
᪉ἲ⤒㐣࡞ࡶࢹ࣮ࢱ࣮࣋ࢫࡍࡿࡇ࡛, ⒪ࡢ࢚ࣅࢹࣥࢫࢆ✚ࡳୖࡆࡿࡇࡀ࡛
ࡁᚋࡢ⒪᪉㔪ࢆ᳨ウࡍࡿୖ࡛ࡢཧ⪃࡞ࡿ⪃࠼ࡿࠋ
59
ⱥ ⱥᩥせ᪨
In recent years, the development of various diseases in companion animals has risen as their life expectancy has been extended. Among these diseases, cancer in dogs is particularly intractable. Because there are no accurate data on the number of domestic dogs in Japan, there have been no detailed reports on the current state of cancer in dogs in Japan; thus, the incidence of tumors is unknown. Without population data or epidemiological studies, effective management of cancer in dogs in Japan, which are companion animals, is challenging.
We aimed to investigate the status of tumor development in dogs by breed based on 8 years of tumor cases (2005–2012) for which the Department of Veterinary Pathology of the Gifu University received a request for diagnostic examination. We also calculated the crude incidence rate of tumors in dogs by breed based on the results of the survey in 2011 in Gifu prefecture. An age analysis of all samples revealed that the mean age (±
S.D.) at which a tumor developed was 10.4 ± 2.98 years in male dogs and 10.4 ± 2.83 years in female dogs, with no significant difference between males and females. The percentage of malignant tumors in all dogs was 57.5%. Analysis of the ratio of benign to malignant tumors by breed revealed that smaller dogs tended to have a higher ratio of benign tumors. The most common (24.4%) site of tumor development in all dogs was the skin and surrounding tissues. Gastrointestinal tumors were the second most common (18.1%), followed closely by breast tumors (17.8%). There was a tendency for a higher incidence of breast tumors among the smaller dog breeds than in the
medium-to-large dog breeds. We then identified the crude incidence of all tumors (malignant tumors) by breed. Significantly lower rates (p <0.05) were found in the following breeds: Dachshund (DAX) at 0.7%, Shiba (SIB) at 0.5% (0.3%), poodle (PD) at
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0.2% (0.0%), Chihuahua (CW) at 0.3% (0.2%), Pomeranian (POM) at 0.1% (0.1%), and mixed breeds (MIX) at 0.6% (0.4%). The incidence was significantly higher (p < 0.05) in Labrador retriever (LR) at 2.6% (1.9%), Shih Tzu (SZ) at 1.5%, Welsh corgi (CG) at 3.0% (2.1%), Papillion (PAP) at 1.3%, Beagle (BG) at 2.3% (1.8%), Yorkshire terrier (YT) at 1.5%, Golden retriever (GR) at 4.3% (2.8%), Schnauzer (SCH) at 1.5%, Shetland sheepdog (SSD) at 2.5% (1.7%), Maltese dog (MAR) at 2.0%, pug (PG) at 2.1% and Bernese mountain dog (BMD) at 7.9% (6.4%).
Data from a survey of tumor reports from 33.6% of the animal hospitals in Gifu Prefecture, obtained between April 2013 and March 2014, were analyzed for
epidemiologic features, histologically diagnosed tumors, and crude incidence of tumors in domestic dogs (731 diagnostic cases). We adjusted the number of domestic dogs and tumor cases by the response rate to the questionnaire. Among this population, three breeds comprised about half of all family dogs: MIX (22.6%), DAX (13.5%), and SIB (12.2%). The average age of domestic dogs was 8.39 years, which began to decline from age 9 onwards, with dogs aged 15 years or older comprising only 8% of the whole population. The crude incidence of all tumors (malignant tumors) across all breeds was 1.5% (0.6%). In the following breeds, the crude incidence of all tumors (malignant tumors) was significantly higher (p <0.05): DAX, 2.6% (1.3%); SZ, 2.4%; SCH, 2.5%
(1.4%); PG, 3.8% (1.9%); CG, 3.3% (2.2%); BG, 2.2% (1.4%); FB, 3.2% (1.3%); SSD, 3.2%;
LR, 3.2% (2.5%); GR, 2.7% (2.2%); and BMD, 8.2% (7.1%). In other breeds, the crude incidence of all tumors (malignant tumors) was significantly lower (p <0.05): PD, 1.1%
(0.3%); CW, 0.5% (0.3%); POM, 0.9%; SIB, 0.7% (0.3%); and MIX, 1.0% (0.6%).
In order to gain information that could guide future epidemiologic and cancer
prevention studies, we collected data on the deaths of every domestic dog interred at a pet cemetery in Nagoya City. Date of death, age at death, and breed type were
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extracted from the cremation records of 81,065 dogs, and used to calculate a survival curve and longevity for each breed for the period 1985 through 2013. We then analyzed the data for 17,786 dogs born in the 5-year period from 1989 through 1993. The median age at death of all dog breeds was 13.0 years. The five breeds that lived longest were SIB and DAX at 15.0 years, and YT, PD, and MIX at 14.0 years. Both small breeds and medium breeds had a tendency toward long life (14.0 years). By contrast, the following breeds had a shorter-lived tendency: BG, Akita and PG (13.0 years); SCH (12.3 years);
SSD, GR, CK, and Siberian husky (12.0 years); German shepherd and Great Pyrenees (11.0 years); and all other breeds and large breeds 12.0 (years). The mean age at which a tumor developed in all breeds was 10.4–10.5 years, with no correlation between this age and median age of longevity. It is likely that the breeding environment, breed physique, and tumor type all factor into a dog’s life expectancy.
We revealed insufficient only by overseas data, and our country's original data are important to dog cancer measures. We consider that useful, it serve as a reference by compiling data and disease data of the breeding situation of the domestic dog,
treatment strategy or course into a database. Finally, the results of our investigation will aid in the future expansion and practice of Evidence Based Veterinary Medicine (EBVM) in Japan.
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ཧ ཧ⪃ᩥ⊩
(1)Abadie,J.,Hédan,B.,Cadieu,E.,DeBrito,C.,Devauchelle,P.,Bourgain,C.,Parker,H.G.,V aysse,A.,Margaritte-Jeannin,P.,Galibert,F.,Ostrander,E.A. and André,C. (2009).
Epidemiology, pathology, and genetics of histiocytic sarcoma in the Bernese Mountain dog Breed. J. Hered. 100, S19-S27.
(2) Adams,V.J.,Evans,K.M.,Sampson,J. and Wood,J.L.N.(2010). Methods and mortality results of a health survey of purebred dogs in the UK. J.Small Anim.Pract.51,512-524.
(3) Alessandro,D.C.,Benjamino,P.,Gionata,D.V. and Tommaso,I.(2014). Onco-epidemiology of domestic animals and targeted therapeutic attempts: perspectives on human oncology.
J.Cancer.Res.Clin.Oncol.140,1807-1814.
(4) Anfinsen,K.P.,Grotmol,T.,Bruland,O.S.and Jonasdottir,T.J.(2011). Breed-specific incidence rate of canine primary bone tumors- A population based survey of dogs in Norwey. Can.J.Vet.Res.75,209-215㸬
(5) Bonnett,B.N.,Egenvall,A.,Hedhammar,A. and Olson,P.(2005). Mortality in over 350,000 insured Swedish dogs from 1995-2000:I.Breed-, gender-, age- and cause-specific rates.
Acta.Vet.Scand.46,105-120.
(6) BrØnden,L.B.,Eriksen,T. and Kristensen,A.T.(2009). Oral malignant melanomas and other head and neck neoplasms in Danish dogs - data from the Danish Veterinary Cancer Registry.Acta.Vet.Scand.51,54.
(7) BrØnden,L.B.,Nielsen,S.S.,Toft,N.A. and Kristensen,T. (2010). Data from the Danish Veterinary Cancer Registry on the occurrence and distribution of neoplasms in dogs in Denmark.Vet.Rec.166,586-590.
(8) BrØnden,L.B.,Eriksen,T. and Kristensen,A.T. (2010). Mast cell tumors and other skin neoplasia in Danish dogs - data from the Danish Veterinary Cancer Registry.
Acta.Vet.Scand.52,6.
(9) Dobson,J.M.,Samuel,S.,Milstein,H.,Rogers,K. and Wood,J.L.N. (2002). Canine neoplasia in the UK: estimates of incidence rates from a population of insured dogs. J.Small Anim.Pract.43, 240-246.
(10) Dobson, J.M. (2013). Breed-predispositions to cancer in pedigree dogs. ISRN Vet. Sci.
941275.
(11) Dorn,C.R. and Priester,W.A. Epidemiology. pp. 27-52. In: Veterinary Cancer Medicine, 2nd. (Theilen, G.H. and Madewell, B.R. eds.), Lea & Fibiger, Philadelphia.1.
(12) Egenvall,A.,Nødtvedt,A. and von Euler H. (2007). Bone tumors in a population of 400,000 insured Swedish dogs up to 10 y of age: incidence and survival.
Can.J.Vet.Res.71,292-299.
63
(13) Fleming,J.M.,Creevy and Promislow,D.E. (2011). Mortality in North American dogs from 1984 to 2004 : Aninvestigation into age-, size-, and breed-related causes of death.
J.Vet.Internal. Med.25,187-198.
(14) Gaillard,J.M.,Festa-Bianchet,M.,Delorme,D. and Jorgenson,J.(2000). Body mass and individual fitness in female ungulates: bigger is not always better.
Proc.Biol.Sci.267,471-47.
(15) Greer,K.A.,Hughes,L.M. and Masternak,M.M.(2011). Connecting serum IGF-1, body size, and age in the domestic dog. Age.33,475-483.
(16)Grüntzig,K.,Graf,R.,Hässig,M.,Welle,M.,Meier,D.,Lott,G.,Erni,D.,Schenker,N.S.,Gusce tti,F.,Boo,G.,Axhausen,K.,Fabrikant,S.,Folkers,G. and Pospischil,A.(2015). The Swiss canine cancer registry: a retrospective study on the occurrence of tumours in dogs in Switzerland from 1955 to 2008. J.Comp.Pathol.152,161-171.
(17) Hart,B.L.,Hart,L.A.,Thigpen,A.P. and Willits,N.H.(2014). Long-term health effects of neutering dogs: comparison of Labrador Retrievers with Golden Retrievers. 9(7):e102241.
(online), (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096726/), (accessed 2015-10-21)
(18) Hayashidani,H.,Omi,Y.,Ogawa,M. and Fukutomi,K.(1988). Epidemiological Studies on the Expectation of life for Dogs Computed from Animal Cemetery Records.
Jpn.J.Vet.Sci.50,1003-1008.
(19) Herzog,H.A.,Bentley,R.A. and Hahn,M.W. (2004). Random drift and large shifts in popularity of dog breeds. Proc.Biol.Sci.271,353-356.
(20)
ᮾᑦᘯ (2008). ⡿ᅜࡀࢇⓏ㘓ࢆ⏝ࡋࡓデ⒪ࡢ㉁ྥୖάື, ⒴Ꮫ⒪ἲ.
35,1445-1449.
(21)
᪥ᒣ⯅ᙪ, ὠ⇃⚽᫂, ⰼᙬ, ⸨ᮏఀ୕㑻, ྂᕝὒ, ᒾỌ๛ (1994). ᆅᇦࡀࢇⓏ㘓Ꮫ
◊✲,⒴ࡢ⮫ᗋ. 40,123-127.
(22)Itoh,T.,Uchida,K.,Ishikawa,K.,Kushima,K.,Kushima,E.,Tamada,H.,Moritake,T.,Nakao ,H. and Shii,H. (2005). Clinicopathological Survey of 101 Canine Mammary Gland Tumors: Differences between Small-Breed Dogs and Others. J.Vet.Med.Sci. 67, 345-347.
(23) Kraus,C., Pavard, S and Promislow, D.E. (2013). The size-life span trade-off decomposed: why large dogs die young, Am Nat, 181, 492-505.
(24) Leidinger,E.F.,Freeman,K.,Kirtz,G.,Hooijberg,E.H. and Sick,K. (2014). Breed related odds ratio and anatomic distribution of canine mast cell tumours in Austria.
Retrospective study of cases in the years 2000-2010.Tierarztl Prax Ausg K Kleintiere Heimtiere.42,367-373.
(25) Llewellyn,A.(2014). Pedigree dog health survey. Vet.J.202,471-476.
(26) Jitpean,S.,Hagman,R.,Ström,H.B.,Höglund,O.V.,Pettersson,A and Egenvall,A. (2012).
Breed variations in the incidence of pyometra and mammary tumours in Swedish dogs.
Reprod.Domest.Anim.47,347-350.
64
(27) MacVean, D.W., Monlux, A.W., Anderson, P.S.Jr., Silberg, S.L. and Roszel, J.F. (1978).
Frequency of canine and feline tumors in a defined population. Vet. Pathol. 15, 700-715.
(28)Merlo,D.F.,Rossi,L.,Pellegrino,C.,Ceppi,M.,Cardellino,U.,Capurro,C.,Ratto,A.,Sambucc o,P.L.,Sestito,V.,Tanara,G. and Bocchini,V. (2008). Cancer Incidence in Pet Dogs : Findings of the Animal Tumor Registry of Genoa, Italy. J.Vet.Intern.Med.22,976-984.
(29) Moe,L. (2001). Population-based incidence of mammary tumors in some dog breeds.
J.Reprod.Fertil.Suppl.57,439-443.
(30) Morris,J. and Dobson,J. (2001). Introduction pp.2-3. In: Small Animal Oncology, (Morris, J. and Dobson, J. eds.), Blackwell Science, Oxford.
(31) Nødtvedt,A.,Berke,O.,Bonnett,B.N. and Brønden,L. (2011). Current status of canine cancer registration - report from an international workshop. Vet.Comp.Oncol.10,95-101.
(32) Nødtvedt,A.,Gamlem,H.,Gunnes,G.,Grotmol,T.,Indrebø,A. and Moe,L. (2010). Breed differences in the proportional morbidity of testicular tumors and distribution of histopathologic types in a population-based canine cancer registry.
Vet.Comp.Oncol.9,45-54.
(33) Ostrander,E.A. (2012). Franklin H. Epstein Lecture. Both ends of the leash--the human links to good dogs with bad genes. N.Engl. J.Med.367,636-646.
(34) Patronek G, Waters DJ and Glickman LT. (1997). Compalative longevity of pet dogs and humans: implications for gerontology reseach., The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 52, B171-B178.
(35) Pelander,L.,Ljungvall,.I,Egenvall,A.,Syme,H.,Elliott,J. and Häggström,J. (2014).
Incidence of and mortality from kidney disease in over 600,000 insured Swedish dogs.
Vet.Rec.23,597-598.
(36) Proschowsky,H.F.,Rugbjerg,H.and Ersboll,A.K. (2003). Mortality of purebred and mixed-breed dogs in Denmark. Prev.Vet.Med.58,63㹼74
(37) Ricardo,U and Noel,S. (2005). Diet, nutrition, and the life-course approach to cancer prevention. J.Nutr.135,2934S-2945S.
(38) Selman,C.,Nussey,D.H. and Monaghan,P. (2013). Ageing: it's a dog's life.
Curr.Biol.23,451-453.
(39)
ᓥᮧ㯞Ꮚ. (2012). ᐙᗞ࠺ࡪࡘ་⒪࠾ࡅࡿಖ㝤㔠ᨭᡶ࠸ࢹ࣮ࢱࡢά⏝. ⋇་Ꮫ㞧ㄅ.
16, 67-73.
(40) Sutter,N.B.,Bustamante,C.D.,Chase,K.,Gray,M.M.,Zhao,K.,
Zhu,L.,Padhukasahasram,B.,Karlins,E.,Davis,S.,Jones,P.G.,Quignon,P.,Johnson,G.S.,P arker,H.G.,Fretwell,N.,Mosher,D.S.,Lawler,D.F.,Satyaraj,E.,Nordborg,M.,Lark,K.G.,Wa yne,R.K. and Ostrander,E.A. (2007). A single IGF1 allele is a major determinant of small size in dogs. Science.316,112-115.