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別紙4

研究成果の刊行に関する一覧表

雑誌

  発表者氏名   論文タイトル名   発表誌名   巻号   ページ   出版年 Terracina KP,

Aoyagi T, Huan g W, Nagahash i M, Yamada A, Aoki K, Tak abe K.

Development of a metastatic murine colon cancer model.

J Surg Res in press

Narumi K, Miy akawa R, Ueda R, Hashimoto H, Yamamoto Y, Yoshida T, Aoki K.

Pro-inflammatory pr oteins S100A8/S100A 9 activate natural ki ller cells via Interact ion with a receptor of advanced glycatio n endproduct.

J Immunol 194 5539-5548 2015

Hashimoto H, Ueda R, Narum i K, Heike Y, Y oshida T, Aoki K.

Type I IFN gene del ivery suppresses reg ulatory T cells withi n tumors.

Cancer Gene

Ther 21 532-541 2014

Yamamoto Y, H iraoka N, Goto N, Rin Y, Miur a K, Narumi K, Uchida H, Tag awa M, Aoki K.

A targeting ligand e nhances infectivity a nd cytotoxicity of an oncolytic adenovirus in human pancreati c cancer tissues.

J Control Re

lease 192 284-293 2014

Inagawa Y, Ya mada K, Yuga wa Y, Ohno S, Hiraoka N, Esa ki M, Shibata T, Aoki K, Say a Y, Kiyono T.

A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.

Carcinogenes

is 35 1840-1846 2014

Yamamoto Y, G oto N, Miura K, Narumi K, Ohnami S, Ush ida H, Miura Y, Yamamoto M, Aoki K.

Development of a no vel efficient method to construct an aden

ovirus library displa ying random peptide s on the fiber knob.

Mol Pharma

ceutics 11 1069-1074 2014

(2)

37 Aida K, Miyaka

wa R, Suzuki K, Narumi K, Udagawa T, Ya mamoto Y, Chi karaishi T, Yos hida T, Aoki K.

Suppression of Tregs by anti-GITR antib ody enhances the an titumor immunity of IFN-α gene therapy for pancreatic cance r.

Cancer Sci 105 159-167 2014

Takagi-kimura M, Yamano T, Tagawa M, Ku bo S.

Oncolytic virotherapy for osteosarcoma us ing midkine promote r-regulated adenovir uses.

Cancer Gene

Ther 21 126-132 2014

Tagawa M, Shi rane K, Yu L, Sato T, Furuka wa S, Mizuguch i H, Kuji R, Ka wamura K, Tak ahashi N, Kato K, Hayakawa S, Sawada S, F urukawa K.

Enhanced expression

of the

β4-galactosyltransfer ase 2 gene impairs mammalian tumor growth.

Cancer Gene

Ther 21 219-227 2014

Fukamachi T, I keda S, Saito H, Tagawa M, Kobayashi H.

Expression of acidosi s-dependent genes in human cancer nest s.

Mol Clin On

col 2 1160-1166 2014

Suzuki T, Kaw amura K, Li Q, Okamoto S, T ada Y, Tatsumi K, Shimada H, Hiroshima K, Y amaguchi N, T agawa M.

Mesenchymal stem c ells are efficiently tr ansduced with adeno viruses bearing type 35-derived fibers and the transduced cells with the IL-28A ge ne produces cytotoxic ity to lung carcinom a cells co-cultured.

BMC Cancer 14 713 2014

Okamoto S, Jia ng Y, Kawamur a k, Shingyoji M, Tada Y, Sek ine I, Takiguchi Y, Tatsumi K, Kobayashi H, Shimada H, Hi roshima K, Tag awa M.

Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.

Cell Death a

nd Disease 5 e1517 2014

(3)

38 Zhong B, Ma

G, Sato A, Shi mozato O, Liu H, Li Q, Shing yoji M, Tada Y, Tatsumi K, Sh imada H, Hiros hima K, Tagaw a M.

Fas Ligand DNA En hances a Vaccination Effect by Coadminis tered DNA Encoding a Tumor Antigen t hrough Augmenting Production of Antibo dy against the Tumo r Antigen.

J Immunol

Res Vol.2015 743828 2015

Li Q, Sato A, S himozato O, Shi ngyoji M, Tada Y, Tatsumi K, Shimada H, Hir oshima K, Taga wa M.

Administration of D NA encoding the int erleukin-27 gene aug ments anti-tumor res ponses through non- adaptive immunity.

Scand J Im

munol in press

Ma G, Zhong B,Okamoto S, J iang Y, Kawam ura K, Liu H, Li Q, Shingyoji M, Sekine I, Ta da Y, Tatsumi K, Shimada H, Hiroshima K, T agawa M.

A combinatory use of adenoviruses expres sing melanoma differ entiation-associated g ene-7 and replication -competent adenoviru ses produces synergi stic effects on pancre atic carcinoma cells.

Tumor Biol in press

Shimizu K, Sak urai F, Tomita K, Nagamoto Y, Nakamura SI, Katayama K, T achibana M, Ka wabata K, Mizu guchi H.

Suppression of leaky expression of adeno virus genes by insert ion of microRNA-targ eted sequences in th e replication-incompe tent adenovirus vecto r genome.

Mol Ther M ethods Clin Dev

1 14035 2014

Hemmi M, Tac hibana M, Tsuz uki S, Shoji M, Sakurai F, Ka wabata K, Kobi yama K, Ishii KJ, Akira S, M izuguchi H.

The early activation of CD8+ T cells is d ependent on type I I FN signaling followi ng intramuscular va ccination of adenovir us vector.

Biomed Res

Int Vol.2014 158128 2014

Miyagawa Y, M arino P, Verlen gia G, Uchida H, Goins WF, Yokota S,Geller DA, Yoshida O, Mester J, Co hen JB, Glorios o JC.

Herpes simplex viral -vector design for eff icient transduction of nonneuronal cells w ithout cytotoxicity.

PNAS 112 E1632-164

1 2015

(4)

39 Nishii Y, Yama

guchi M, Kimur a Y, Hasegawa T, Aburatani H, Uchida H, Hir ata K, Sakuma Y.

A newly developed a nti-Mucin 13 monocl onal antibody targets pancreatic ductal ad enocarcinoma cells.

Int J Oncol 46 1781-1787 2015

Mazzacurati L, Marzulli M, Rei nhart B, Miyag awa Y, Uchida H, Goins WF, L i A, Kaur B, C aligiuri M, Crip e T, Chiocca N, Amankulor N, Cohen JB, Glori oso JC, Grandi P.

Use of miRNA respo nse sequences to blo ck off-target replicati on and increase the safety of an unatten uated, glioblastoma-t argeted oncolytic HS V.

Mol Ther 23 99-107 2014

Yamaguchi M, Nishii Y, Naka mura K, Aoki H, Hirai S, Uch ida H, Sakuma Y, Hamada H.

Development of a se nsitive screening met hod for selecting mo noclonal antibodies t o be internalized by cells.

Biochem Bio phys Res Co mmun

454 600-603 2014

Okazaki Y, Wa ng Y, Tanaka H, Mizuno M, Nakamura K, K ajiyama H, Kan o H, Uchida K, Kikkawa F, H ori M, Toyokuni S.

Direct exposure of n on-equilibrium atmos pheric pressure plas ma confers simultan eous oxidative and u ltraviolet modificatio ns in biomolecules.

J Clin Bioch

em Nutr Vol.55 207-215 2014

Torii K, Yamad a S, Nakamura K, Tanaka H, Kajiyama H, T anahashi K, Iw ata N, Kanda M, Kobayashi D, Tanaka C, F ujii T, Nakaya ma G, Koike M, Sugimoto H, Nomoto S, Nat sume A, Fujiwa ra M, Mizuno M, Hori M, Say a H, Kodera Y.

Effectiveness of plas ma treatment on ga stric cancer cells.

Gastric Canc

er 2014

Publish on line

(5)

40 Cao D, Kishida

S, Huang P, Mu P, Tsubota S, Mizuno M, Kadomatsu K.

A new tumorsphere culture condition res tores potentials of se lf-renewal and metas tasis of primary neu roblastoma in a mou se neuroblastoma mo del.

PLoS One 9(1) e86813 2014

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