子宮内膜症患者の月経随伴症状と QOL に関する研究－子宮内膜症の早期発見に向けて－

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(1)qÿĊþķĆŌ. -!7. ç óë´ e * Ĉ Œ e Į õ eÇZ°ÖÒ eÇZ*ĩc e ĵ Î . Æ. §. Ì. . . ~ŕþķŖ ċ 7 ¯Â 26 ° 3 Ö 5 Ò eīuċ 4 Ûċ 1 őı¶Ě þķĀĉĆþķ¦Ë ¢oġø¾Ě*ÖĒōdøð& )ŋ;Āĉ ŗ¢oġø*ÓØûĪ)$ŗ Menstrual symptoms and quality of life of endometriosis patientsśtowards early detection of endometriosis. ÌÇśôÏlÔŕ\ŖÌÇśà_ăŕxŖ. ĵ Î ¤ Þ \Þś«îłÌÇx\ÞśáŅĹ½ÌÇx\Þśąó±ėpÌÇ.

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(7) Ö Ö Ē)ŋ;ģª@HGOTKÃ*Èß Āĉ 1 9 3 *ēÝ?ļ2ñåĞ(°Ŕ©*¼ ¢oġø*ÓØûĪ)#(;ģª@HGOTK?Øü) Ñ%;ģª@HGOTKÃ? Èß ģª@HGOTKÃ+Ę{Ìĝ*ĳć% Ñ<;¼Ìĝ*Ŏ2 Ìĝâŋ7ě* Øm´İÐ*İ*Ŏ)tòzÝü(jmÆ§)ñ&Ğ&ę; }úâŋ?İ; Ŏ)+Ã?Å}¬7þķ¬.*¡ĭü(¿?Èi;&%`Ć÷¾*üā(İÐ7èú ?§&)Ė;%=

(8) ēĵ aºy^ì<;¢oġø*ÓØûĪ)$a*ĀĉēÝéò<;&?Ø¹ $; ÚĀĉ%Èß ¢oġø*ÓØûĪ* 5*ģª@HGOTKÃ*×z¼?Ô9) ; 5*vĴÞ):đ4»ĩ¼; . Abstract Objective: Endometriosis is a disease with pain and infertility as main symptoms. With the women’s lifestyles changing in recent years, the incidence of endometriosis is on the increase and the Quality of Life (QOL) of.

(9) qÿĊþķĆŌ. endometriosis patient has been declining. We carried out the following three studies to investigate menstrual symptoms, risk factors and actual QOL of endometriosis patients. Based on one results, we proposed the means of detection of endometriosis. Study 1: A questionnaire survey was given to 330 endometriosis patients and 194 healthy women. Menstrual symptoms were severe in endometriosis patients compared to healthy women and their risk of endometriosis was also higher. It took the patients an average of 11 years to be clinically diagnosed from the time they recognized the pain. Study 2: The SF-8 Health Survey acute form was used to investigate the Health Related QOL (HRQOL) of 154 endometriosis patients and 193 healthy women. The HRQOL of the endometriosis patients was markedly lower compared to the healthy women. The more severe the menstrual symptoms of the patients were, the lower their HRQOL scores. The following four symptoms affected the Physical Component Summary (PCS) scores of the patients: “pain medication does not work”, “lower abdominal pain and backache persist even after the menstrual period”, “hypermenorrhea“ and “deep anal pain during menstrual period”. The following two symptoms affected the Mental Component Summary (MCS) scores: “lower abdominal pain and backache persist even after the menstrual period” and “pain medication does not work”. Study 3: Menstrual blood loss for one cycle of 160 healthy women, between the ages of 19 and 39 years, was measured. They were also given a questionnaire survey to obtain their menstruation information, self-awareness of menstrual blood loss and pain symptoms. The data for 133 women with regular menstrual cycles (menstrual cycle between 25 to 38 days) was analyzed. The average age of menarche was 12.2 years, average duration of menstrual period was 5.4 days, average menstrual cycle was 29.5 days and average total menstrual blood loss of one cycle was 77.4 g. With regard to menstrual blood loss, 3.0% of participants had hypomenorrhea (≤20g), 88.7% had normal menorrhea (>20g and <140g) and 8.3% had hypermenorrhea (≥140g). Actual measured menstrual blood loss did not match self-awareness in 26.5% of the participants. In regards to the relationship between menstrual blood loss and symptoms of pain during menstruation, the total menstrual blood loss for those with backaches was on average 84.6 g and it was significantly more than those without backaches whose total menstrual blood loss was on average 67.5 g. Proposal for a Menstruation Self-Assessment Handbook: Based on the results of this study, we proposed a self-assessment handbook so that women of childbearing age can regularly do a self-assessment for early detection of endometriosis. The self-assessment handbook could be used in the sex education curriculum of the Japanese compulsory education system and in history taking at periodical health examination at schools and workplaces. We expected that the handbook has been used effectively as a public health guidance tool. Bringing the handbook to medical visits and providing objective information to doctors and nurses could lead to accurate diagnosis and treatment of gynecological disorders. Conclusion: We hope that the results of this study will be used for the early detection of endometriosis, the incidence of which is expected to rise in the future. A prospective study is needed to determine the effectiveness the self-assessment handbook proposed in this study for early detection of endometriosis.

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子宮内膜症患者の月経随伴症状と QOL に関する研究 －子宮内膜症の早期発見に向けて－

子宮内膜症患者の月経随伴症状と QOL に関する研究－子宮内膜症の早期発見に向けて－