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標識反応後の精製なしに生体内微量分子の画像化を可能とする67/68Ga標識多価プローブの作製に関する研究

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Academic year: 2021

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Figure 1. A schematic illustration of radiometal-labeled probe. A biomolecule is conjugated  with a bifunctional chelator to produce a biomolecule chelator probe which called ligand
Figure 3. A conceptual illustration of the in situ molecular design of multivalent probes
Figure 5. Analysis of [ 67 Ga]Ga-(Hdpp) 3 . CAE radioactivity traces of (A) [ 67 Ga]Ga-(Hdpp) 3  and  (B)  [ 67 Ga]Ga-citrate
Figure 6. RP-HPLC UV (254 nm) traces of Ga-(PTSC-1) 2  (A) and Ga-(PTSC-2) 2  (B)  and radioactivity traces of [ 67 Ga]Ga-(PTSC-1) 2  (C) and [ 67 Ga]Ga-(PTSC-2) 2  (D)
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