Metformin prevents liver tumorigenesis induced by highfat diet in C57Bl6 Mice

Recently, it was reported that ketoconazole, which is a well-known inhibitor of CYP3A4, potently inhibits the morphine glucuronosyltransferase activity catalyzed by recombinant UGT2B7

Gemcitabine induced CXCL8 mRNA expression (data not shown) and CXCL8 protein expression in pancreatic cancer cells in xenografted tumor tissues (Figure 4A).. We

induced CXCL8 mRNA expression (data not shown) and CXCL8 protein expression in pancreatic cancer cells in xenografted tumor tissues (Fig.. We next administered anti-CXCL8 antibody

Methods: Organ-specific IR in the liver (hepatic glucose production (HGP)6 fasting plasma insulin (FPI) and suppression of HGP by insulin [%HGP]), skeletal muscle

Pim-3, a proto-oncogene with serine ⁄ threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates Bad to block Bad-mediated apoptosis in

In progressive kidney fibrosis induced by a ureteral ligation in mice, CD45- and type I collagen-dual positive fibrocytes (CD45 + /ColI + ) infiltrated the interstitium, especially

In summary, we described an elderly woman without pre- existing renal dysfunction who developed severe hyper- magnesemia after oral ingestion of a massive Mg-containing cathartic.

We measured blood levels of adiponectin in SeP knockout mice fed a high sucrose, high fat diet to examine whether SeP was related to the development of hypoadiponectinemia induced