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Magnetic resonance imaging evaluation of the labrum to predict acetabular development in developmental dysplasia of the hip<Abstract of dissertation>

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Nagoya City University Academic Repository

学 位 の 種 類 博士 (医学) 報 告 番 号 甲第1596号 学 位 記 番 号 第1134号 氏 名 白井 康裕 授 与 年 月 日 平成 29 年 8 月 31 日 学位論文の題名

Magnetic resonance imaging evaluation of the labrum to predict acetabular development in developmental dysplasia of the hip

(MRI の関節唇評価による発育性股関節形成不全における臼蓋発育の予測)

Medicine.Vol.96:2: P. e7013, 2017

論文審査担当者 主査: 芝本 雄太

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Magnetic resonance imaging evaluation of the labrum to predict acetabular

development in developmental dysplasia of the hip

Abstract

Background: It is often difficult to make a judgment in patients with residual hip

dysplasia (RHD) after the initial treatment of developmental dysplasia of the hip. On the other hand, more attention has been paid to the role of the acetabular labrum recently. Therefore, we designed a retrospective cohort study of patients with residual hip dysplasia (RHD) who underwent magnetic resonance imaging (MRI). The objective of this study was to investigate an association between the MRI appearance of the labrum and the natural history of RHD.

Methods: We retrospectively investigated 45 hips of 40 patients who underwent MRI at

about 3 and 4 years of age for RHD and were conservatively followed up with until 6 years of age or older. We evaluated the extent of eversion with a new method that measures the β angle (MRI β angle) using landmarks of the Graf method on MRI T2*-weighted images. The outcome measure was the Severin classification at the final follow-up. We compared the radiographic and MRI parameters at approximately 3 and 4 years of age between the good and poor outcome groups.

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Results: Although there was a significant difference in the center-edge (CE) angle,

there was no significant difference in the acetabular index and the ratio of the presence of femoral head necrosis and the break in Shenton line between the good and poor groups. The MRI β angle was significantly greater in the poor outcome group than in the normal and good outcome groups. The cut-off value of the MRI β angle to differentiate the good and poor outcome groups was 65°, and its specificity and sensitivity were 92% and 53%, respectively.

Conclusions: There was labral eversion on MRI scans in patients with RHD.

Acetabular development before adolescence was poorer with greater labral eversion on MRI scans. The specificity for poor acetabular development was high when the MRI β angle was 65° or more. The MRI β angle has the potential to predict acetabular

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