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A Failure to Confirm the Effectiveness of a Brief Group Psychoeducational Program for Mothers of Children with High-functioning Pervasive Developmental Disorders : A Randomized Controlled Pilot Trial<Abstract of dissertation>

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Nagoya City University Academic Repository

学 位 の 種 類 博士 (医学) 報 告 番 号 甲第1433号 学 位 記 番 号 第1038号 氏 名 鈴木 真佐子 授 与 年 月 日 平成 26 年 3 月 25 日 学位論文の題名

A Failure to Confirm the Effectiveness of a Brief Group Psychoeducational Program for Mothers of Children with High-functioning Pervasive Developmental Disorders: A Randomized Controlled Pilot Trial

(高機能広汎性発達障害児の母親の精神的支援のための短期家族心理教育 の有用性の検証:無作為化比較試験)

Neuropsychiatric Disease and Treatment,2014 (In Press)

論文審査担当者 主査: 齋藤 伸治

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A Failure to Confirm the Effectiveness of a Brief Group Psychoeducational Program for Mothers of Children with High-functioning Pervasive Developmental Disorders: A Randomized Controlled Pilot Trial

M. Suzuki1), A. Yamada1), N. Watanabe1), F. Katsuki2), M. Imaeda3), Y. Mitsuda4), K. Otaki5),

T. Nishiyama6), T. Akechi1), T. A. Furukawa7)

1) Nagoya City University Graduate School of Medical Sciences, Department of Psychiatry

2) Nagoya City University School of Nursing, Department of Psychiatric and Mental Health Nursing

3) Nagoya City University Graduate School of Medical Sciences, Department of Neonatology and Pediatrics 4) Toyokawa Sakura Hospital

5) Kazuo Mental Clinic

6) Nagoya City University Graduate School of Medical Sciences, Department of Public Health

7) Kyoto University Graduate School of Medicine / School of Public Health, Department of Health Promotion and Human Behavior

Objective: The purpose of this trial is to examine the effectiveness of group psychoeducational psychotherapy aimed at alleviating the psychological distress of mothers with the children of high-functioning pervasive developmental disorders (HFPDD) and improving the behaviors of the children with disorder traits, in a randomized controlled trial.

Methods: Mothers of preschool outpatients with HFPDD were randomly assigned either to

biweekly, seven weeks psychoeducational intervention added to treatment as usual (TAU) or to TAU alone. We evaluated maternal mental health, caregiver burden, maternal quality of life and aberrant behavior of children at baseline (week 0), at the end of intervention (week 7) and at week 21 after randomization. We tested group effects with interaction between the intervention and the evaluation points.

Results: The GHQ-28 score at week 21 was significantly higher in the GP+TAU group as compared to that in the TAU-alone group, indicating a greater improvement in the TAU-alone than that of the GP +TAU. There was no evidence that GP+TAU led to a greater improvement of the maternal mental health than TAU-alone at week 7. Similarly, no evidence was obtained to indicate that GP + TAU led to a reduction in the ABC or ZBI scores by week 7 or 21. The adjusted scores for the RF (role emotional) and MH (mental health) subscales of the SF-36 at week 21 were also significantly lower in the GP+TAU group, indicating a similar tendency to that of the change of the GHQ-28 score at week 21. Conclusion: The psychoeducational program did not alleviate the maternal distress, aberrant behaviors of the children, or the caregiver burden.

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