Distinct promoter usage of mdm2 gene in human breast cancer

Second, it was revealed that ADAR1-mediated RNA editing positively regulates DHFR expression in human breast cancer-derived MCF-7 cells by destroying miR- 25-3p and miR-125a-3p

(24) Similarly, T26 inhibited both Pim-3 kinase activity in a cell-free system and in vitro cell proliferation of human pancreatic cancer cell lines at micromo- lar

reported that gemcitabine-mediated apoptosis is caspase- dependent in pancreatic cancers; Jones et al [14] showed that gemcitabine-induced apoptosis is achieved through the

Gene expression levels and promoter usage of NR4A family NGFIB, NURR1, NOR1, NR5A1 and CYP11B2 in human cardiovascular and adrenal tissues.. a mRNA expression levels

Although mouse NS was included in the leukaemia stem cell gene signature, NS expression levels were not significantly different among AML patient clusters in our study (data

As it is involved in cell growth, IER3 expression has been examined in several human tumors, including pancreatic carcinoma, ovarian carcinoma, breast cancer, and

To determine the promoter activities of 5 ′ -flanking region of the human Pim-3 gene, we subcloned various deleted 5 ′ -flanking regions of the human Pim-3 gene into a

Pim-3, a proto-oncogene with serine ⁄ threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates Bad to block Bad-mediated apoptosis in