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民族薬物研究センター Research Center for Ethnomedicine

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民族薬物研究センター

Research Center for Ethnomedicine

国際共同研究分野

Division of International Cooperative Research

客員教授 Rungpetch C. Sakulbumrungsil(Ph.D)

客員教授(前) Jun Yin(Ph.D)

客員教授 Nguyen Minh Khoi(Ph.D)

客員教授 Du Jinhang (Ph.D)

◆ 研究概要

目覚ましい発展を遂げた現代西洋医学においても治療に難渋する疾患が多く,天然物を活用した伝統医学に関する研究 成果や臨床効果に期待が寄せられている.伝統医学に関わる研究を高い水準で維持・発展させるためには,最新の研究方 法論や天然物に関する情報交換が必要である.和漢医薬学総合研究所は天然物の研究を発展させるために,3カ国・4 関との間に国際協力拠点(ICC)を形成するとともに,8カ国・17機関と部局間協定を締結している.

そこで,民族薬物研究センター国際共同研究分野は,各国の大学及び研究機関の研究者と連携して,伝統医学と現代医 学を融合した国際共同研究を促進することを目的に,1)タイ・チュラロンコン大学薬学部や中国・北京大学医学部薬学 院との国際協力拠点を通した国際共同研究の推進,2)大学間や部局間協定締結機関とのジョイントシンポジウム,学生 交流を通した国際共同研究の維持・発展を図っている.

◆ 原 著

1) Tangcharoensathien V, Sommanustweechai A, Chanthong B, Sumpradit N, Sakulbumrungsil R, Jaroenpoj S, Sermsinsiri V;

Thai SAC Working Group. Surveillance of antimicrobial consumption: methodological review for systems development in Thailand. J Glob Health. 2017 Jun; 7(1): 010307. doi: 10.7189/jogh.07.010307. Review. PubMed PMID: 28702173; PubMed Central PMCID: PMC5502706.2017年未掲載分)

2) Zhai J, Zhang F, Gao S, Chen L, Feng G, Yin J, Chen W. Schisandra chinensis extract decreases chloroacetaldehyde production in rats and attenuates cyclophosphamide toxicity in liver, kidney and brain. J Ethnopharmacol. 2018 Jan 10; 210: 223-31. doi:

10.1016/j.jep.2017.08.020. Epub 2017 Aug 15. PubMed PMID: 28821392.

3) Zhou J, Song Z, Han M, Yu B, Lv G, Han N, Liu Z, Yin J. Evaluation of the antithrombotic activity of Zhi-Xiong Capsules, a Traditional Chinese Medicinal formula, via the pathway of anti-coagulation, anti-platelet activation and anti-fibrinolysis.

Biomed Pharmacother. 2018 Jan; 97: 1622-31. doi: 10.1016/j.biopha.2017.11.135.

4) Ha DT, Long PT, Hien TT, Tuan DT, An NTT, Khoi NM, Van Oanh H, Hung TM. Anti-inflammatory effect of oligostilbenoids from Vitis heyneana in LPS-stimulated RAW 264.7 macrophages via suppressing the NF-κB activation. Chem Cent J. 2018 Feb 13; 12(1): 14. doi: 10.1186/s13065-018-0386-5. PubMed PMID: 29442202; PubMed Central PMCID: PMC5811415.

5) Chang S, Yang Z, Han N, Liu Z, Yin J. The antithrombotic, anticoagulant activity and toxicity research of ambinine, an alkaloid from the tuber of Corydalis ambigua var. amurensis. Regul Toxicol Pharmacol. 2018 Mar 7. pii: S0273-2300(18)30067-9. doi:

10.1016/j.yrtph.2018.03.004. [Epub ahead of print]

6) Ngoc TM, Phuong NTT, Khoi NM, Park S, Kwak HJ, Nhiem NX, Trang BTT, Tai BH, Song JH, Ko HJ, Kim SH. A new naphthoquinone analogue and antiviral constituents from the root of Rhinacanthus nasutus. Nat Prod Res. 2018 Mar 21: 1-7.

doi: 10.1080/14786419.2018.1452004. [Epub ahead of print] PubMed PMID: 29561167.

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