Variation of pH and DK Values of Solution of Ingredient in Blood by r-Ray Irradiation

Vol. 20 (1983) i!i~*$JJjFrjJijJf~iYTif$G

I Materials I

Variation of pH and DK Values of Solution of Ingredient in Blood by r-Ray Irradiation

Isao

OGURA,

Masamichi

EGASHIRA,

Masao Y

AMAGUCHI*

and Shosaku

KINOSHITA **

(Received September 26, 1983)

KEYWORDS

DK (Dielectric constant). 'Y-Ray. Urea, Uric acid, Lactic acid. Fibrinogen, Globlin.

As a means of an examination on an agency of radiant rays to the living body, some of ingredient in blood were irradiated with 'Y-ray come from 60CO. A trial was practiced if pH and DK values fit in a dosimeter from a comparison of a dose and a varied amount. As the reagents, urea uric acid, lactic acid, fibrinogen. a-, (3- and 'Y-globlin were placed to the service of irradiation.

These solutions were irradiated to lO^Z, 10^3, 10^4, 10^5, 10⁶ and 10⁷R (dose rate lO^zR .. 2 x lO^Z, 10³ and 10⁴R .. 2.44 X 10^4, 10^5, 10⁶ and 10⁷R .. 5.8 x 10⁶R/h). The pH and DK values of these original and irradi- ated solution were measured and those values were showed in Table I and Fig. 1 and 2. pH indi- cated the large values at the start, but it became to the small values according to the increase of dose.

In contrast with this, DK pointed to the small values in the first place, but after that those took the large one according to the increase of dose. From these results, it seemed to be possible that the radiant dose was estimated from the change of DK values of these reagent's solution.

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102 103 104 105 106 107 R Fig. 1 Change of pH of Components in Blood

by Irradiation of 60CO 'Y-Ray

1; ,8-Globulin 2; a-Globulin 3; Fibrinogen 4; ry-GlobuIin 5; Vrea 6; Uric Acid 7; Lactic Acid

*

Wakayama Medical College

**

Radiation Center of Osaka Prefecture

65

60

55

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_{102 103 104 105 106 107R}

Fig. 2 Change of DK Values of Components in Blood by Irradiation of 60CO 'Y-Ray 1; Lactic Acid 2; ry-Globulin 3; V ric Acid 4; Urea 5; (3-Globulin 6; Fibrinogen 7; a-·Globulin

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OGURA etc: Variation of pH and DK Values of Solution of Ingredient in Blood by 'Y-Ray Irradiation

Table 1 Change of pH and DK Values of Solution by 'Y-Irradiation

~-

^Dose

^{0 10}

²

¹⁽⁾³

_I

^{1Q4 10}

^{5 I}

¹⁰

⁶

I

10

⁷R ---

---

'"

^'-~ Dose Rate

"

-,'-..,- ---~

Sample ~ pH DK

2X 10

²

2.44X1Q4 5.8X 10

⁶ Rlh

pH

5.18 5.73 5.64 5.64 5.40 5.10 4.49

Urea DK

52.44 51.28 51.12 52.44 55.00 62.06 58.09

pH

4.30 4.29 4.28 4.30 4.30 4.28 4.16

Uric acid DK

53.51 51.53 52.09 52.72 52.87 62.31 61.87

pH

3.98 4.20 4.23 4.15 3.95 3.94 3.79

Lactic acid

DK

51. 79 51.87 53.71 54.81 55.51 59.73 63.26

pH

5.08 5.45 5.50 5.63 5.29 5.01 4.93

Fibri-nogen DK

51.69 52.29 53.04 52.39 51.56 56.20 58.23

pH

5.36 5.90 5.67 5.87 5.49 5.04 4.55

a-Globulin DK

52.85 50.43 51.82 51.32 51.93 52.54 57.67

pH

5.75 5.75 5.77 6.06 5.50 5.30 4.60

,8-Globulin DK

50.45 51.95 53.63 52.93 54.13 52.91 56.65

I

pH

I

5.00 5.65 5.53 5.93 5.44 5.50 4.68

'Y-Globulin DK

53.49 53.11 52.67 53.46 57.43 59.54 62.19

Acknowlegement The authors want to express the appreciation tor the use of a part of the found from Japan Private School Promotion Foundation.

Reference

P. Neta, R. W. Fessenden, R. H. Schuler, J. Phys. Chern, 75,

1654(1971)

C. Lagercrantz, ibid., 75,

1654 (1971)

Y. Hashimoto etc., Radiochemistry and Health physics (Japanese) (Hirokawashoten)

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