つくばリポジトリ JCBN 61 3
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Gemcitabine induced CXCL8 mRNA expression (data not shown) and CXCL8 protein expression in pancreatic cancer cells in xenografted tumor tissues (Figure 4A).. We
Accordingly, our results showed that kahweol acetate and cafestol inhibited the proliferation and migration of both ACHN and Caki-1 cells, with their synergistic effects apparent
Character- ization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue. IGFBP-4 is an inhibitor of canonical Wnt signalling
Memory CD4+ T cells were able to respond to a pair of anti-CD2 mAbs (anti-T112 and anti-T113) to proliferate even in the absence of monocytes, whereas any proliferative re-
(14) Similarly, as observed on other members of Pim family, (15,16) we demonstrated that aberrantly expressed Pim-3 can inactivate a pro-apoptotic BH3-only Bcl-2-like molecule,
To determine the promoter activities of 5 ′ -flanking region of the human Pim-3 gene, we subcloned various deleted 5 ′ -flanking regions of the human Pim-3 gene into a
Pim-3, a proto-oncogene with serine ⁄ threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates Bad to block Bad-mediated apoptosis in
Here, cell surface localization of MT1-MMP and activation of MMP-2 were clearly induced in mesothelioma cells even when expression of integrin 1 was substantially abolished..